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From prediction to prevention:machine learning revolutionizes hepatocellular carcinoma recurrence monitoring

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World Journal of Gastroenterology 2024年第7期30卷 631-635页

作者： mariana michelle Ramírez-mejía Nahum méndez-sánchez Plan of Combined studies in medicine Faculty of MedicineNational Autonomous University of MexicoDistrito Federal 04510Mexico Liver Research Unit Medica Sur Clinic&FoundationDistrito Federal 14050Mexico Faculty of medicine National Autonomous University of MexicoDistrito Federal 04510Mexico

In this editorial,we comment on the article by Zhang et al entitled Development of a machine learning-based model for predicting the risk of early postoperative recurrence of hepatocellular *** carcinoma(HCC),which is characterized by high incidence and mortality rates,remains a major global health challenge primarily due to the critical issue of postoperative *** recurrence,defined as recurrence that occurs within 2 years posttreatment,is linked to the hidden spread of the primary tumor and significantly impacts patient *** predictive factors,including both patient-and treatment-related factors,have limited predictive ability with respect to HCC *** integration of machine learning algorithms is fueled by the exponential growth of computational power and has revolutionized HCC *** study by Zhang et al demonstrated the use of a groundbreaking preoperative prediction model for early postoperative HCC *** persist,including sample size constraints,issues with handling data,and the need for further validation and *** study emphasizes the need for collaborative efforts,multicenter studies and comparative analyses to validate and refine the *** these challenges and exploring innovative approaches,such as multi-omics integration,will enhance personalized oncology *** study marks a significant stride toward precise,efficient,and personalized oncology practices,thus offering hope for improved patient outcom.s.in the field of HCC treatment.

关键词： Hepatocellular carcinoma Early recurrence machine learning XGBoost model Predictive precision medicine Clinical utility Personalized interventions

Does enhanced recovery after surgery programs improve clinical outcom.s.in liver cancer surgery?

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 255-258页

作者： Belinda sánchez-Pérez Josém Ramia Department of General Digestive and Transplantation SurgeryUniversity Regional HospitalMálaga 29010MálagaSpain Department of surgery Hospital General Universitario Dr.BalmisAlicante 03010Spain

Enhanced recovery after surgery(ERAs)programs have been widely applied in liver surgery since the publication of the first ERAs guidelines in 2016 and the new recommendations in *** surgery is usually performed in oncological patients(liver metastasis,hepatocellular carcinoma,cholangiocarcinoma,etc.),but the real impact of liver surgery ERAs programs in oncological outcom.s.is not clearly *** advantages of ERAs programs are:ERAs decreases postoperative complication rates and has been demonstrated a clear relationship between complications and oncological outcom.s.a better and faster posto-perative recovery should let oncologic teams begin chemotherapeutic regimens on time;prehabilitation and nutrition actions before surgery should also improve the performance status of the patients receiving ***,ERAs could be another way to improve our oncological *** will discuss the literature about liver surgery ERAs focusing on its oncological implications and future investigations projects.

关键词： Enhanced recovery after surgery programs Liver surgery Key components Long-term oncological outcomes Enhanced recovery after surgery compliance

Common coupled fixed point theorem for two pairs compatible and sub-sequentially continuous mapping

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Journal of Ocean Engineering and science 2024年第4期9卷 401-407页

作者： H.m.Abu-Donia mona s.Bakry H.A.Atia Omnia m.A.Khater Raghda A.m.Attia Department of mathematics Faculty of ScienceZagazig UniversityZagazigEgypt Department of mathematics Faculty of ScienceTanta UniversityTantaEgypt Department of Basic science Zagazig Higher Institute of Engineering and TechnologyZagazigEgypt Department of Basic science Higher Technological Institute 10th of Ramadan CityEl Sharqia 44634Egypt

This study establishes a common coupled fixed point for two pairs of compatible and sequentially continuous mappings in the intuitionistic fuzzy metric space that satisfy theφ-contractive *** basic definitions and theorems have been used from.s.me recent scientific papers about the binary operator,t-norm,t-conorm,intuitionistic fuzzy metric space,and compatible mapping for reaching to the paper’s purpose.

关键词： Intuitionistic fuzzy metric space φ-contractive mapping Compatible mappings Couple fixed point

C-phycocyanin shows neuroprotective effect against rotenone-induced Parkinson’s disease in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 279-287页

作者： Hritik Rathod Ritu m.s.ni Jigna s.shah Department of Pharmacology Institute of Pharmacy Nirma UniversityAhmedabadGujaratIndia

Objective:To investigate the neuroprotective effect of C-phycocyanin in a mouse model of rotenone-induced Parkinson’s ***:C-phycocyanin(50 mg/kg,i.p.,daily)was administered to rotenone(30 mg/kg,p.o.,daily)treated mice for 28 *** studies(Y-maze,rotarod,round beam walk,and wire-hang tests)were carried out to assess neurobehavioral *** and malondialdehyde were determined in both serum and striatal *** proteins(AKT,AmPK,NF-κB,BDNF,and alpha-synuclein)in the striatum were estimated using *** analyses(hematoxylin and eosin stainning as well as Nissl staining)were carried out to assess structural abnormalities in the ***:C-phycocyanin significantly increased BDNF levels and decreased alpha-synuclein *** also slightly upregulated AmPK and AKT levels without significant difference compared with the rotenone ***,rotenone-induced elevated oxidative stress and structural abnormalities in the striatum were markedly mitigated by ***:C-phycocyanin might have potential neuroprotective effects against Parkinson’s *** studies are warranted to verify its efficacy and to understand the molecular mechanisms behind the neuroprotective effects of C-phycocyanin in Parkinson’s disease.

关键词： Parkinson’s disease C-phycocyanin Alphasynuclein BDNF Oxidative stress Rotenone

A critical review towards the causes of the iron-based catalysts deactivation mechanisms in the selective oxidation of hydrogen sulfide to elemental sulfur from biogas

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Journal of Energy Chem.s.ry 2024年第3期90卷 388-411,I0010页

作者： m.s.afa Tarek Janaina s.santos Victor márquez mohammad Fereidooni mohammad Yazdanpanah supareak Praserthdam Piyasan Praserthdam Center of Excellence on Catalysis and Catalytic Reaction Engineering(CECC) Department of Chemical EngineeringFaculty of EngineeringChulalongkorn UniversityBangkok 10330Thailan High-Performance Computing Unit(CECC-HCU) Center of Excellence on Catalysis and Catalytic Reaction Engineering(CECC)Chulalongkorn UniversityBangkok 10330Thailand

Hydrogen sulfide(H_(2)s) not only presents significant environmental concerns but also induces severe corrosion in industrial equipment,even at low *** various technologies,the selective oxidation of hydrogen sulfide(sOH_(2)s) to elemental sulfur(s) has emerged as a sustainable and environmentally friendly *** to its unique properties,iron oxide has been extensively investigated as a catalyst for sOH_(2)s;however,rapid deactivation has remained a significant *** causes of iron oxide-based catalysts deactivation mechanisms in sOH_(2)s,including sulfur or sulfate deposition,the transformation of iron species,sintering and excessive oxygen vacancy formation,and active site loss,are thoroughly examined in this *** focusing on the deactivation mechanisms,this review aims to provide valuable insights into enhancing the stability and efficiency of iron-based catalysts for sOH_(2)s.

关键词： selective oxidation of H_(2)s Iron-based Catalysts mechanism of deactivation sulfur or sulfate deposition Transformation of iron species sintering sDG 7

Rare earth-doped mixed Ni-Cu-Zn ferrites as an effective photocatalytic agent for active degradation of Rhodamine B dye

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Journal of Rare Earths 2024年第3期42卷 488-496,I0003页

作者： swapnil A.Jadhav sandeep B.somvanshi sudarshan s.Gawali Kranti Zakde K.m.Jadhav Department of Physics Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad431004MaharashtraIndia school of materials Engineering Purdue UniversityWest Lafayette 47906USA University Department of Basic and Applied sciences MGM UniversityAurangabad431003MaharashtraIndia

In this study, a series of Gd^(3+)-doped mixed Ni-Cu-Zn ferrites with composition of Zn_(0.5)Ni_(0.3)Cu_(0.2)Fe_(2-x)Gd_(x)O_(4)(x = 0, 0.025, 0.05, 0.075, 0.1) was prepared using self-ignition sol-gel method. The prepared nanoparticles with an average size ranging from 22 to 26 nm.s.ow a single-phase cubic structure belonging to the spinel matrix. A rise in the Gd^(3+)concentration leads to an increase in crystallite size and lattice parameter. In Fourier transform infrared spectra, two main absorption bands belonging to the spinel structure are observed. The high-frequency bands(v_(1)) represent the tetrahedral complex, while the lowfrequency bands(v_(2)) signify the octahedral complex. The optical bandgap of the nanoferrites is found within the range of 2.91 to 2.41 eV, depending on their size. The magnetic characteristics of the material,such as saturation magnetization and coercivity are significantly altered with the concentration of Gd^(3+)in the solution. Using Rhodamine B(RhB) as a model organic pollutant, an in-depth investigation of the photocatalytic activity of the compounds was carried out. The present outcom.s.show that adding an adequate amount of Gd^(3+)significantly enhances the number of hydroxyl radicals produced by the ferrite,in turn, increasing the photocatalytic activity of the material. mechanism elucidated by scavenger studies reveals that ·OH and holes are the primary reactive radicals responsible for the degradation *** photocatalysts show an insignificant performance loss in five consecutive cycles. Thus, it is concluded that these photocatalysts are highly suitable for the remediation of dye-contaminated wastewater.

关键词： Gd^(3+)substitution spinel ferrite structural properties magnetic properties Photocatalysis Rare earths

Hybrid-Vlasov simulation of soft X-ray em.s.ions at the Earth’s dayside magnetospheric boundaries

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Earth and Planetary Physics 2024年第1期8卷 70-88页

作者： m.Grandin H.K.Connor s.Hoilijoki m.Battarbee Y.Pfau-Kempf U.Ganse K.Papadakis m.Palmroth Department of Physics University of HelsinkiHelsinkiFinland NAsA Goddard space Flight Center GreenbeltMD20771USA space and Earth Observation Centre Finnish Meteorological InstituteHelsinkiFinland

solar wind charge exchange produces em.s.ions in the soft X-ray energy range which can enable the study of near-Earth space regions such as the magnetopause,the magnetosheath and the polar cusps by remote sensing *** solar wind magnetosphere Ionosphere Link Explorer(smILE)and Lunar Environment heliospheric X-ray Imager(LEXI)m.s.ions aim to obtain soft Xray images of near-Earth space thanks to their soft X-ray Imager(sXI)*** earlier modeling works have already simulated soft X-ray images as might be obtained by smILE sXI during its m.s.ion,the numerical models used so far are all based on the magnetohydrodynamics description of the space *** investigate the possible signatures of ion-kinetic-scale processes in soft Xray images,we use for the first time a global hybrid-Vlasov simulation of the geospace from the Vlasiator *** simulation is driven by fast and tenuous solar wind conditions and purely southward interplanetary magnetic *** first produce global X-ray images of the dayside near-Earth space by placing a virtual imaging satellite at two different locations,providing meridional and equatorial *** then analyze regional features present in the images and show that they correspond to signatures in soft X-ray em.s.ions of mirrormode wave structures in the magnetosheath and flux transfer events(FTEs)at the *** results suggest that,although the time scales associated with the motion of those transient phenomena will likely be significantly smaller than the integration time of the smILE and LEXI imagers,mirror-mode structures and FTEs can cumulatively produce detectable signatures in the soft X-ray *** instance,a local increase by 30%in the proton density at the dayside magnetopause resulting from the transit of multiple FTEs leads to a 12%enhancement in the line-of-sight-and time-integrated soft X-ray em.s.ivity originating from this ***,a proton density increase by 14%in the magnetosheath

关键词： magnetosphere magnetosheath numerical simulation smILE LEXI soft X-ray em.s.ions hybrid-Vlasov model polar cusp flux transfer events mirror-mode waves

Effect of solidification cooling rate on microstructure and tribology characteristics of Zn-4si alloy

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International Journal of minerals,metallurgy and materials 2024年第2期31卷 362-373页

作者： F.Akbari m.Golkaram.s.Beyrami G.shirazi K.mantashloo R.Taghiabadi m.s.ghafi Yazdi I.Ansarian Department of metallurgy and material science Imam Khomeini International University(IKIU)Qazvin ***Iran

The main objective of this work was to modify the microstructure and enhance the tribological properties of a new Zn-4si al-loy through a high solidification cooling rate(sCR).According to the results,by increasing the sCR from 2.0 to 59.5℃/s the average size of primary si particles and that of the grains reduced from 76.1 and 3780μm to less than about 14.6 and 460μm,***-ing the sCR also enhanced the microstructural homogeneity,decreased the porosity content(by 50%),and increased the matrix hardness(by 36%).These microstructural changes enhanced the tribological *** instance,under the applied pressure of 0.5 mPa,an in-crease in the sCR from 2.0 to 59.5℃/s decreased the wear rate and the average friction coefficient of the alloy by 57%and 23%,*** wear mechanism was also changed from the severe delamination,adhesion,and abrasion in the slowly-cooled alloy to the mild tribolayer delamination/abrasion in the high-cooling-rate-solidified sample.

关键词： zinc-silicon alloy primary silicon solidification cooling rate tribology sliding wear

microalgae cultivation in photobioreactors: sustainable solutions for a greener future

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Green Chemical Engineering 2024年第4期5卷 418-439页

作者： shaikh Abdur Razzak Khairul Bahar K.m.Oajedul Islam Abdul Khaleel Haniffa mohammed Omar Faruque s.m.Zakir Hossain mohammad m.Hossain Chemical Engineering Department King Fahd University of Petroleum and Minerals Center for Refining and Advanced Chemicals King Fahd University of Petroleum & Minerals Department of Chemical Engineering University of Bahrain

microalgae cultivation in photobioreactors（PBRs） has emerged as a prom.s.ng and sustainable approach to address various environmental and energy challenges, offering a multitude of benefits across diverse *** developments in microalgae cultivation in photobioreactors have contributed substantially to the development and optimization of sustainable bioprocesses. This review presents a comprehensive analysis of recent innovations and breakthroughs in the field of microalgae cultivation, with a specific focus on their application in photobioreactors, aimed at paving the way for a greener future. This study in-depth examines the advantages of microalgae cultivation in photobioreactors, concentrating on its effectiveness in wastewater treatment, CO2bioremediation, and the production of biofuels and high-value products. The review evaluates the effects of light,solar irradiation, temperature, nitrogen and phosphorus concentrations in culture media, CO2concentrations, and pH on microalgae growth performance, including specific growth and biom.s. productivity. The study also examines open systems like unstirred ponds, raceway ponds, and circular ponds and closed systems like horizontal tubular, vertical bubble-column, airlift, flat panel, and plastic-bag photobioreactors, comparing their pros and cons. To optimize microalgae cultivation, key factors in photobioreactor design, including photosynthetic efficiencies, light/dark（L/D） cycles, CO2concentrations, m.s. transfer, hydrodynamics behavior, and p H, are extensively investigated. In addition, the review outlines recent developments in large-scale photobioreactors and highlights the challenges and opportunities associated with photobioreactor scale-up and design parameter optimization, including genetic engineering and economic feasibility. This article is a vital resource for researchers, engineers, and industry professionals seeking sustainable bioprocesses and the application of microalgae-based technol

关键词： microalgae biom.s. CO 2 biofixation Wastewater treatment Biofuel Photobioreactors