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Are there sex-based disparities in cataract surgery?

International journal of Ophthalmology(English edition) 2024年第1期17卷 137-143页

作者： matthew d.geiger Anne m.Lynch Alan g.Palestine Nathan C.grove karen L.Christopher richard s.davidson michael j.Taravella Naresh mandava jennifer L.Patnaik department of Ophthalmology University of Colorado School of MedicineAuroraCO 80045USA

AIm:To investigate sex-based differences in the occurrence of intra-operative and post-operative complications and associated visual outcom.s following cataract ***:This was a retrospective study of patients who had phacoemulsification cataract surgery at the University of Colorado school of *** collected included the patient’s health history,ocular comorbidities,operative and post-operative complications,and the post-operative best corrected visual acuity(BCVA).The data were analyzed using univariate and multivariable logistic regression with generalized estimating equations to account for the correlation of some patients having two eyes included in the ***:A total of 11977 eyes from 7253 patients were included in the *** comorbidities differed by sex,with males having significantly higher percentages of traumatic cataracts(males 0.7%vs females 0.1%),prior ocular surgery(6.7%vs 5.5%),and mature cataracts(2.8%vs 1.9%).Conversely,females had significantly higher rates of pseudoexfoliation(2.0%vs 3.2%).In unadjusted analysis,males had higher rates of posterior capsular rupture(0.8%vs 0.4%)and vitreous loss(1.0%vs 0.6%),but this difference was not significant after adjustment for *** had a significantly increased risk of post-operative retinal detachment,but in multivariable analysis this was no longer *** were significantly less likely to undergo post-operative neodymium-doped yttrium aluminum garnet(Nd:YAg)laser capsulotomy for posterior capsule opacification(Or=0.8,95%CI=0.7-0.9,P=0.0005).The BCVA was slightly worse for males pre-operatively;but post-operatively,both sexes exhibited similar visual acuity of snellen equivalent 20/***:The study finds that in a cohort of patients presenting for cataract surgery,sex differences exist in pre-operative comorbidities and surgical characteristics that contribute to higher rates of some complications for ***,observed surgical complicatio

关键词： cataract surgery sex-based disparity phacoemulsification outcom.s

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Li_(6)gd(BO_(3))_(3)晶体生长及热性能

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硅酸盐学报 2024年第5期52卷 1589-1596页

作者：任伊扬王鹏马云峰张明荣张春生徐家跃上海应用技术大学材料科学与工程学院上海201418 福建理工大学材料科学与工程学院福州350118 北京玻璃研究院有限公司北京101111

Li_(6)gd(BO_(3))_(3)(LgBO)晶体具有优异的综合性能,是潜在的中子探测、激光和发光材料。但是,由于硼酸盐熔体粘度大、晶体易开裂,晶体生长非常困难。采用坩埚下降法生长出尺寸为φ20mm×30mm透明晶体,探讨了高黏度晶体的生长机理,研... 详细信息

Li_(6)gd(BO_(3))_(3)(LgBO)晶体具有优异的综合性能,是潜在的中子探测、激光和发光材料。但是,由于硼酸盐熔体粘度大、晶体易开裂,晶体生长非常困难。采用坩埚下降法生长出尺寸为φ20mm×30mm透明晶体,探讨了高黏度晶体的生长机理,研究了晶体的光谱和热物理性能。35℃下晶体比热容为0.898 j/(g·k),300℃时上升到1.18 j/(g·k);30℃下和方向热膨胀系数分别为12.768×10^(-6)k^(-1)和21.146×10^(-6)k^(-1),随温度升高表现出显著的各向异性;室温下其热导率分别为2.72 W/(m·k)和2.60 W/(m·k)。较大的比热容有利于LgBO晶体在高功率状态下稳定工作。

关键词：硼酸钆锂晶体坩埚下降法晶体生长热性能

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祁连山东段冷龙岭地区宁缠河3号冰川变化研究

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冰川冻土 2012年第5期34卷 1031-1036页

作者：刘宇硕秦翔张通张明杰杜文涛中国科学院寒区旱区环境与工程研究所冰冻圈科学国家重点实验室祁连山冰川与生态环境观测研究站甘肃兰州730000 兰州大学资源环境学院甘肃兰州730000 中国科学院寒区旱区环境与工程研究所冰冻圈科学国家重点实验室甘肃兰州730000

2009年7月对祁连山东段冷龙岭地区宁缠河3号冰川进行了野外考察,对冰川周围布设测量控制网,并利用gPs-rTk技术测量了冰川表面高程与面积、末端等信息,同时使用加拿大EkkO型探地雷达测量了冰川厚度.结合1972年航测1973年调绘出版的地形... 详细信息

2009年7月对祁连山东段冷龙岭地区宁缠河3号冰川进行了野外考察,对冰川周围布设测量控制网,并利用gPs-rTk技术测量了冰川表面高程与面积、末端等信息,同时使用加拿大EkkO型探地雷达测量了冰川厚度.结合1972年航测1973年调绘出版的地形图以及1995年与2009年两景Tm影像等资料,分析研究了宁缠河3号冰川自1972年以来的变化.结果表明:宁缠河3号冰川近37a以来萎缩严重,冰川末端退缩约6%,面积减小13.1%,冰川体积减少35.3%;冰川主要以减薄的形式在萎缩,冰川平均厚度由1972年的36.8m,减为2009年的27.4m.周边站点气象资料表明,该区域近几十年来出现不同程度的升温,是导致冰川快速萎缩的主要原因.

关键词：宁缠河3号冰川冰川变化冰川萎缩祁连山

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聚乙烯醇/聚乙烯亚胺基双网络导电复合水凝胶的制备及传感应用

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中国科学：化学 2024年第7期54卷 1107-1116页

作者：王子琦向楚阳钟彦庚辰刘明杰付如民周蕾谭帼馨广东工业大学轻工化工学院广州510006 华南理工大学材料科学与工程学院国家人体组织功能重建工程技术研究中心广州510006 广州医科大学附属第三医院脊柱外科广州510145

聚乙烯醇(PVA)基导电水凝胶在人体健康监测、软机器人、柔性可穿戴电子设备等领域的研究受到广泛关注.本工作将聚吡咯@聚多巴胺纳米粒子(PPy@PdA NPs)分散在聚乙烯醇(PVA)/聚乙烯亚胺(PEI)预凝胶溶液中,通过冻融循环法制备聚乙烯醇/聚... 详细信息

聚乙烯醇(PVA)基导电水凝胶在人体健康监测、软机器人、柔性可穿戴电子设备等领域的研究受到广泛关注.本工作将聚吡咯@聚多巴胺纳米粒子(PPy@PdA NPs)分散在聚乙烯醇(PVA)/聚乙烯亚胺(PEI)预凝胶溶液中,通过冻融循环法制备聚乙烯醇/聚乙烯亚胺/聚吡咯@聚多巴胺纳米粒子导电复合水凝胶(PPN).研究结果表明, PPN具有优秀的机械性能,其断裂应变为507%,最大拉伸强度为158.59 kPa,对于皮肤有着良好的黏附性能,黏附强度为21.49 kPa,PPN最大电导率为0.28 s/m,并且具有优秀的生物相容性,通过?r/r0-t曲线证明该水凝胶可以用于检测人体运动信号与信号输入. PPN水凝胶在柔性传感领域有着良好的应用前景.

关键词：水凝胶聚乙烯醇聚吡咯传感器

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A facile strategy for tuning the density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications

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Bio-design and manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.Beeren g.dos santos P.j.dijkstra C.mota j.Bauer H.Ferreira rui L.reis N.Neves s.Camarero-Espinosa m.B.Baker L.moroni department of Complex Tissue regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3B’s research group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVs/3B’s-PT government Associate Laboratory 4806-909 Braga/GuimarãesPortugal POLYmAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IkErBAsQUE Basque Foundation for Science48009 BilbaoSpain

melt extrusion-based additive manufacturing(mE-Am)is a prom.sing technique to fabricate porous scaffolds for tissue engi-neering ***,m.st synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell *** of biomolecules on polymeric surfaces of Am.scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface ***,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(PCL5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight PCL75k at different *** porous three-dimensional(3d)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight PCL *** a proof-of-concept test,we prepared films of three different m.ss ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).subsequently,a bone morphogenetic protein 2(BmP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human m.senchymal stromal cells(hmsCs)was *** two weeks of culturing in a basic medium,cells expressed higher levels of BmP receptor II(BmPrII)on films with the conjugated *** addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface *** together,these results emphasize that the density of surface peptides on cell differentiation m.st be considered at the cell-material ***,we have presented a viable strategy for mE-Am community that desires to tune the bulk and surface functionality via blending of(m

关键词： Additive manufacturing Blending surface functionalization surface density Click chem.stry Human

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Elucidating regulatory processes of intense physical activity by multi-omics analysis

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military medical research 2024年第4期11卷 479-499页

作者： Ernesto s.Nakayasu marina A.gritsenko Young-mo kim jennifer E.kyle kelly g.stratton Carrie d.Nicora Nathalie munoz kathleen m.Navarro daniel Claborne Yuqian gao karl k.Weitz Vanessa L.Paurus kent j.Bloodsworth kelsey A.Allen Lisa m.Bramer Fernando montes kathleen A.Clark grant Tietje justin Teeguarden kristin E.Burnum-johnson Biological sciences division Pacific Northwest National LaboratoryRichlandWA 99352USA Environmental and molecular sciences division Pacific Northwest National LaboratoryRichlandWA 99352USA Centers for disease Control and Prevention National Institute for Occupational Safety and HealthWestern States DivisionDenverCO 80204USA Computational Analytics division Pacific Northwest National LaboratoryRichlandWA 99352USA National security directorate Pacific Northwest National LaboratoryRichlandWA 99352USA Los Angeles County Fire department Los AngelesCA 90063USA Centers for disease Control and Prevention National Institute for Occupational Safety and HealthRespiratory Health DivisionMorgantownWV 26505USA Environmental and molecular Toxicology Oregon State UniversityCorvallisOR 97331USA

Background:Physiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations,such as firefighting,law enforcement,military,and sports.A better understanding of such processes can ultimately help improve human performance and prevent illnesses in the work ***:To study regulatory processes in intense physical activity simulating real-life conditions,we performed a multi-omics analysis of 3 biofluids(blood plasma,urine,and saliva)collected from 11 wildland firefighters before and after a 45 min,intense exercise *** profiles ***-exercise were compared by student’s t-test followed by pathway analysis and comparison between the different omics ***:Our multi-omics analysis identified and quantified 3835 proteins,730 lipids and 182 metabolites combining the 3 different types of *** blood plasma analysis revealed signatures of tissue damage and acute repair response accompanied by enhanced carbon metabolism to meet energy *** urine analysis showed a strong,concomitant regulation of 6 out of 8 identified proteins from the renin-angiotensin system.supporting increased excretion of catabolites,reabsorption of nutrients and maintenance of fluid *** saliva,we observed a decrease in 3 pro-inflammatory cytokines and an increase in 8 antimicrobial peptides.A systematic literature review identified 6 papers that support an altered susceptibility to respiratory ***:This study shows simultaneous regulatory signatures in biofluids indicative of homeostatic maintenance during intense physical activity with possible effects on increased infection susceptibility,suggesting that caution against respiratory diseases could benefit workers on highly physical demanding jobs.

关键词： multi-omics analysis Intense exercise Human performance Biofluids metabolism Immunity

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magnetic Topological dirac semimetal Transition driven by sOC in Eumg_(2)Bi_(2)

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Chinese Physics Letters 2024年第1期41卷 63-67页

作者：王佳萌钱浩吉姜琦乔山叶茂 state key Laboratory of Functional materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China Center of materials science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China research Center for Intelligent Chips and devices Zhejiang LabHangzhou 311121China Center for Transformative science ShanghaiTech UniversityShanghai 201210China school of Physical science and Technology ShanghaiTech UniversityShanghai 201210China shanghai synchrotron radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

magnetic topological semimetals have been at the forefront of condensed matter physics due to their ability to exhibit exotic transport *** the interplay between magnetic and topological orders in systems with broken time-reversal symmetry is crucial for realizing non-trivial quantum *** delve into the electronic structure of the rare-earth-based antiferromagnetic dirac semimetal Eumg_(2)Bi_(2) using first-principles calculations and angle-resolved photoem.ssion *** calculations reveal that the spin-orbit coupling(sOC)in Eumg_(2)Bi_(2) prompts an insulator to topological semimetal transition,with the dirac bands protected by crystal *** linearly dispersive states near the Fermi level,primarily originating from Bi 6p orbitals,are observed on both the(001)and(100)surfaces,confirming that Eumg_(2)Bi_(2) is a three-dimensional topological dirac *** research offers pivotal insights into the interplay between magnetism.sOC and topological phase transitions in spintronics applications.

关键词： spectroscopy topological dirac

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基于状态空间模型的激光再制造熔池温度控制系统

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表面工程与再制造 2024年第2期24卷 50-50页

作者： Yang g.-Z. Liu T.-m. song B.-X. jiang X.-Y. Wang Z.-s. Chen k.-Q. Liu W.-j. school of mechanical Engineering Shenyang University of Technology Shenyang China

激光再制造是用于再制造的一项重要技术,在航空航天、冶金、能源等领域应用广泛。然而,形状控制问题一直是制约其规模化和工业化应用的瓶颈。在激光再制造过程中,熔池温度是决定再制造件形状和性能稳定性的关键。基于此,本文提出了一种... 详细信息

激光再制造是用于再制造的一项重要技术,在航空航天、冶金、能源等领域应用广泛。然而,形状控制问题一直是制约其规模化和工业化应用的瓶颈。在激光再制造过程中,熔池温度是决定再制造件形状和性能稳定性的关键。基于此,本文提出了一种基于状态空间模型的激光再制造熔池温度实时在线控制方法,解决了控制机理模型难以建立和多变量约束的问题。

关键词：状态空间模型激光再制造熔池温度航空航天形状控制控制系统变量约束性能稳定性

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Phase composition,conductivity,and sensor properties of cerium-doped indium oxide

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Nano materials science 2024年第2期6卷 193-200页

作者： m.I.Ikim g.N.gerasimov V.F.gromov O.j.Ilegbusi L.I.Trakhtenberg N.N.semenov Federal research Center for Chemical Physics of rAs MoscowRussia University of Central Florida OrlandoFLUSA m.scow Institute of Physics and Technology(state University) DolgoprudnyMoscow RegionRussia Lomonosov m.scow state University MoscowRussia

The hydrothermal synthesis of In_(2)O_(3)and CeO_(2)–In_(2)O_(3)is investigated as well as the properties of sensor layers based on these *** the synthesis of In_(2)O_(3),intermediate products In(OH)_(3)and InOOH are formed,which are the precursors of stable cubic(c-In_(2)O_(3))and metastable rhombohedral(rh-In_(2)O_(3))phases,respectively.A transition from c-In_(2)O_(3)to rh-In_(2)O_(3)is observed with the addition of CeO_(2).The introduction of cerium into rh-In_(2)O_(3)results in a decrease in the sensor response to hydrogen,while it increases in composites based on c-In_(2)O_(3).The data on the sensor activity of the composites correlate with XPs results in which CeO_(2)causes a decrease in the concentrations of chem.sorbed oxygen and oxygen vacancies in rh-In_(2)O_(3).The reverse situation is observed in composites based on c-In_(2)O_(3).Compared to In_(2)O_(3)and CeO_(2)–In_(2)O_(3)obtained by other methods,the synthesized composites demonstrate maximum response to H_(2)at low temperatures by 70–100℃,and have short response time(0.2–0.5 s),short recovery time(6–7 s),and long-term.stability.A model is proposed for the dependence of sensitivity on the direction of electron transfer between In_(2)O_(3)and CeO_(2).

关键词： Cerium oxide Indium oxide Nanocomposite Hydrothermal method Cubic phase rhombohedral phase sensor response Conductivity Hydrogen response/recovery time

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不同速度运动状态中竞走运动员下肢动力学特征研究

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西安体育学院学报 2024年第4期41卷 533-543页

作者：张明军蒋秋艳汪红祥潘玮敏西安体育学院运动与健康科学学院西安710068 西安体育学院竞技体育学校西安710068 西安体育学院运动技术分析与技能评定国家体育总局重点实验室西安710068 兰州理工大学设计艺术学院兰州730000 体育智能装备关键技术陕西省高校工程研究中心西安710068

目的通过对中国竞走学校优秀运动员不同速度运动状态中下肢动力学特征的分析,为优化专项技术动作,减少运动损伤发生,强化竞走后备人才训练及竞技水平提高提供参考依据。方法选取中国竞走学校男、女一级及以上重点运动员各8名。依据目前... 详细信息

目的通过对中国竞走学校优秀运动员不同速度运动状态中下肢动力学特征的分析,为优化专项技术动作,减少运动损伤发生,强化竞走后备人才训练及竞技水平提高提供参考依据。方法选取中国竞走学校男、女一级及以上重点运动员各8名。依据目前青少年竞走运动员不同速度区间的划分,应用sONY dsC-rX10m4高速摄像机和kistler三维测力台同步采集运动员中、高速时下肢的地面反作用力、峰值力和下肢各关节反作用力等动力学数据,应用sImI运动解析软件和matlab软件进行计算,采用单因素方差分析对不同速度下的数据进行比较。结果男运动员高速和中速相比,足外侧地面反作用力峰值高速大于中速,且具有显著性差异(P0.05),髋、膝、踝关节水平和垂直方向峰值力均增加,其中髋、膝、踝关节水平方向峰值力增加幅度分别为22.9%、17.5%、20%,垂直方向峰值力增加幅度分别为2.0%、8.2%、2.7%;女运动员高速与中速相比,足外侧和水平前方向地面反作用力峰值高速大于中速,且具有显著性差异(P0.05),髋、膝、踝关节水平和垂直方向峰值力均增加,其中髋、膝、踝关节水平方向峰值力增加幅度分别为31.6%、26.8%、41.7%,垂直方向峰值力增加幅度分别为7.9%、12.8%、7.4%。结论竞走运动员不同速度运动状态下,男、女运动员在一个步态周期中的地面反作用力在不同方向均为高速大于中速,且均表现为垂直方向分力值最大,内外方向的分力最小,而水平方向制动力峰值均大于加速力峰值,此结果为日常训练加强足跟着地动作技术规范性,同时增加蹬地力量训练,提高下肢肌肉用力水平提供了有力证据;另一方面,男、女运动员髋、膝、踝各关节水平和垂直方向峰值力高速均大于中速,在足跟着地时膝关节和踝关节垂直方向受力较大,髋关节受力较小,而前脚掌蹬离地面时,髋部水平方向转动明显大于垂直方向摆动力度,因而青少年竞走运动员日常训练中需加强髋、膝、踝关节运动链的协同和补偿作用,准确掌握竞走技术动作的用力特点和顺序,对于提高其技术动作合理性和科学性,减少下肢损伤,提高运动表现和比赛成绩具有重要意义。

关键词：不同速度竞走运动员动作技术下肢动力学

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