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Serum bile acid and unsaturated fatty acid profiles of non-alcoholic fatty liver disease in type 2 diabetic patients

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World Journal of Diabetes 2024年第5期15卷 898-913页

作者： Su-Su Feng Si-Jing Wang Lin Guo Pan-Pan ma Xiao-Long ye ming-Lin Pan Bo hang Jian-hua mao Antoine m Snijders Yi-Bing Lu Da-Fa Ding Department of Endocrinology The Second Affiliated Hospital of Nanjing Medical UniversityNanjing 210011Jiangsu ProvinceChina Biological Systems and Engineering Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720United States

BACKGROUND The understanding of bile acid(BA)and unsaturated fatty acid(UFA)profiles,as well as their dysregulation,remains elusive in individuals with type 2 diabetes mellitus(T2Dm)coexisting with non-alcoholic fatty liver disease(NAFLD).Investigating these metabolites could offer valuable insights into the pathophy-siology of NAFLD in *** To identify potential metabolite biomarkers capable of distinguishing between NAFLD and *** A training model was developed involving 399 participants,comprising 113 healthy controls(hCs),134 individuals with T2Dm without NAFLD,and 152 individuals with T2Dm and *** validation encompassed 172 *** patients were divided based on liver fibrosis *** analytical approach employed univariate testing,orthogonal partial least squares-discriminant analysis,logistic regression,receiver operating characteristic curve analysis,and decision curve analysis to pinpoint and assess the diagnostic value of serum *** Compared to hCs,both T2Dm and NAFLD groups exhibited diminished levels of specific *** UFAs,particular acids exhibited a positive correlation with NAFLD risk in T2Dm,while theω-6:ω-3 UFA ratio demonstrated a negative *** ofα-linolenic acid andγ-linolenic acid were linked to significant liver fibrosis in *** validation cohort substantiated the predictive efficacy of these biomarkers for assessing NAFLD risk in T2Dm *** This study underscores the connection between altered BA and UFA profiles and the presence of NAFLD in individuals with T2Dm,proposing their potential as biomarkers in the pathogenesis of NAFLD.

关键词： Bile acid Non-alcoholic fatty liver disease Type 2 diabetes mellitus Unsaturated fatty acid

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World Journal of Otorhinolaryngology-head and Neck Surgery 2024年第2期10卷 97-104页

作者： mihai A.Bentan Evan R.Reiter Richard m.Costanzo Daniel h.Coelho Department of Otolaryngology-head&Neck Surgery Virginia Commonwealth University School of MedicineRichmondVirginiaUSA

Objective:The aim of this study was to review findings from a large prospective national database of chemosensory disturbances associated with coronavirus disease 2019(COVID-19)*** Sources:The Virginia Commonwealth University Smell and Taste Center national database of COVID-19 chemosensory ***:A series of online surveys,first opened on April 10,2020,was made accessible nationwide to any adult with sudden chemosensory dysfunction since January *** received subsequent follow-up surveys 14 days,1 month,3 months,and 6 months after *** additional survey was sent to all participants on may 28,2022 to assess long-term *** pertaining to demographics,symptoms,comorbidities,treatments,and life impact was ***:Of 363 participants who reported complete smell recovery,51.2%recovered within 1 month,70%within 3 months,and 79%within 6 months,while 8.8%took over 1 year to completely *** all participants,7.5%had no smell *** predictors of recovery included agemale gender,and the presence of nasal *** predictors included difficulty breathing and prior head *** participants reported a decrease in quality of life and the presence of potential safety hazards associated with decreased smell ***:most subjects with COVID-19-related chemosensory dysfunction recover,with the majority noting complete recovery within weeks of *** aged over 40 years and female gender were associated with lower rates of recovery.A considerable number of participants reported significant impact on quality of life and safety.

关键词： anosmia COVID-19 smell

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基于扎根理论的乳制品安全综合治理机制政策分析

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食品科学 2024年第8期45卷 272-282页

作者：叶璟李艳南京财经大学管理科学与工程学院江苏南京210023 南京航空航天大学自动化学院江苏南京210016

为提高乳制品安全治理效能,从政策视角探究我国乳制品安全治理的发展脉络和作用机制是必要的。以2002—2021年乳制品政策文本为研究对象,运用扎根理论量化政策文本形成包括治理要素和治理行为的乳制品安全保障体系,并基于量化结果和社... 详细信息

为提高乳制品安全治理效能,从政策视角探究我国乳制品安全治理的发展脉络和作用机制是必要的。以2002—2021年乳制品政策文本为研究对象,运用扎根理论量化政策文本形成包括治理要素和治理行为的乳制品安全保障体系,并基于量化结果和社会网络分析对我国乳制品安全治理演化过程和作用机制进行深入探究。研究发现,我国乳制品安全治理经历了从政府强制监管、应急治理、政主企辅治理到社会共治治理模式的演变过程;整个演变过程体现了国家对治理行动者治理行为与方式的侧重,揭示了乳制品安全综合治理作用机制,治理行动者通过治理行为的相互配合共同作用于治理要素,并经治理要素将其治理作用体现在乳制品安全上,从而保障了乳制品质量安全。

关键词：乳制品安全演化分析政策文本扎根理论社会网络

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警告刺激对驾驶员接管性能的影响机理研究

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交通运输系统工程与信息 2024年第1期24卷 106-114页

作者：王丹林业天津科技大学机械工程学院天津300457

为研究不同模态警告刺激对接管性能的影响机理,本文重点关注在不同非驾驶相关任务和触发场景下,单一模态和双模态警告刺激对驾驶员的预警效果。搭建不同警告刺激下,驾驶员接管车辆控制权的台架试验,采集49名驾驶员的眼动数据与车辆数据... 详细信息

为研究不同模态警告刺激对接管性能的影响机理,本文重点关注在不同非驾驶相关任务和触发场景下,单一模态和双模态警告刺激对驾驶员的预警效果。搭建不同警告刺激下,驾驶员接管车辆控制权的台架试验,采集49名驾驶员的眼动数据与车辆数据,并开展显著性影响分析。研究结果表明,警告类型对接管时间和首次注视时间有显著影响,从事非驾驶相关任务对驾驶员的接管时间产生负面影响,双模态警告刺激的首次注视时间低于单一模态的首次注视时间。在视觉和触觉警告刺激下,非驾驶相关任务下的最大横向加速度为0.36 m·s^(-2),监控任务下为0.34 m·s^(-2),相对其他警告刺激,横向加速度最小,车辆接管更稳定,接管质量最高。双模态警告刺激的横摆角整体小于单一模态警告刺激,车辆更加稳定,而在单一模态警告刺激下,视觉警告刺激的最大横向加速度为0.45 m·s^(-2),相对其他警告刺激,横向加速度最大,接管绩效最差。不同模态警告刺激对接管方式无显著影响。双模态的警告刺激类型相较于单一模态而言,更加依赖于多种感官效果,提供更全面和更准确的警示信息,特别是与驾驶员身体接触的触觉振动警告方式。

关键词：智能交通警告刺激双因素方差分析人机接管眼动数据车辆动力学

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high-Efficiency Photo-Induced Charge Transfer for SERS Sensing in N-Doped 3D-Graphene on Si heterojunction

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Energy & Environmental materials 2024年第2期7卷 272-280页

作者： Guanglin Zhang Jie Sun Genwang Wei Shan Zhang Zhengyi he huijuan Wu Bingkun Wang Siwei Yang Guqiao Ding Zhiduo Liu Zhiwen Jin Caichao ye Gang Wang Department of microelectronic Science and Engineering School of Physical Science and Technology Ningbo University Department of Biochemistry and molecular Biology School of Basic Medical Sciences Shenzhen University Academy for Advanced Interdisciplinary Studies & Department of materials Science and Engineering Guangdong Provincial Key Laboratory of Computational Science and Material Design Southern University of Science and Technology State Key Laboratory of Functional materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Centre for Quantum Physics Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement (MOE) School of Physics Beijing Institute of Technology School of Physical Science and Technology & Key Laboratory for magnetism and magnetic materials of the ministry of Education Lanzhou University

Nitrogen-doped three-dimensional graphene（N-doped 3D-graphene） is a graphene derivative with excellent adsorption capacity, large specific surface area, high porosity, and optoelectronic properties. herein, N-doped 3Dgraphene/Si heterojunctions were grown in situ directly on silicon（Si）substrates via plasma-assisted chemical vapor deposition（PACVD）, which is promising for surface-enhanced Raman scattering（SERS） substrates candidates. Combined analyses of theoretical simulation, incorporating N atoms in 3D-graphene are beneficial to increase the electronic state density of the system and enhance the charge transfer between the substrate and the target molecules. The enhancement of the optical and electric fields benefits from the stronger light-matter interaction improved by the natural nano-resonator structure of N-doped 3D-graphene. The as-prepared SERS substrates based on N-doped 3D-graphene/Si heterojunctions achieve ultralow detection for various molecules: 10-8m for methylene blue（mB） and10-9m for crystal violet（CRV） with rhodamine（R6G） of 10-10m. In practical detected, 10-8m thiram was precisely detected in apple peel extract. The results indicate that N-doped 3D-graphene/Si heterojunctions based-SERS substrates have promising applications in low-concentration molecular detection and food safety.

关键词： charge transfer DFT simulation N-doped 3D-graphene SERS Thiram detection

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小细胞外囊泡及其携带的非编码RNA在非酒精性脂肪性肝病中的作用

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生物化学与生物物理进展 2024年第5期51卷 1054-1066页

作者：李想李晔昆明理工大学基础医学院昆明650500

小细胞外囊泡(small extracellular vesicles,sEVs)是由细胞分泌的一种细胞外囊泡,产生于多泡体,多泡体与质膜融合并释放到细胞外基质。由于小细胞外囊泡可以携带分子质量相对较小的核酸、蛋白质、脂质,能够执行细胞间物质传递、细胞间... 详细信息

小细胞外囊泡(small extracellular vesicles,sEVs)是由细胞分泌的一种细胞外囊泡,产生于多泡体,多泡体与质膜融合并释放到细胞外基质。由于小细胞外囊泡可以携带分子质量相对较小的核酸、蛋白质、脂质,能够执行细胞间物质传递、细胞间通讯等功能。因此,小细胞外囊泡及其携带的非编码RNA不仅参与细胞正常生理过程,也可以在多种疾病的发生发展过程中起重要作用。本文综述了小细胞外囊泡在非酒精性脂肪性肝病(NAFLD)中的作用,小细胞外囊泡及其携带的非编码RNA不仅有望成为NAFLD诊断的标志物,同时也具有治疗NAFLD的潜在作用,或能为治疗NAFLD提供新思路。

关键词：小细胞外囊泡非酒精性脂肪性肝病非编码RNA 微小RNA 长链非编码RNA 环状RNA

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mitochondrial Regulation of macrophages in Innate Immunity and Diverse Roles of macrophages During Cochlear Inflammation

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Neuroscience Bulletin 2024年第2期40卷 255-267页

作者： Yuan Zhang Fanglei ye Xiaolong Fu Shen Li Le Wang Yutian Chen hongmin Li Shaojuan hao Kun Zhao Qi Feng Peipei Li Department of Otology The First Afliated Hospital of Zhengzhou UniversityZhengzhou 450052China Shandong Provincial hospital Shandong First Medical UniversityJinan 250000China Department of Neurology The First Afliated Hospital of Zhengzhou UniversityZhengzhou 450052China The Department of Endovascular Surgery The First Afliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Integrated Traditional and Western Nephrology The First Afliated Hospital of Zhengzhou UniversityZhengzhou 450052China henan Province Research Center of Kidney Disease Zhengzhou 450052China

macrophages are essential components of the innate immune system and constitute a non-specific first line of host defense against pathogens and *** regulate macrophage activation and innate immune responses in various inflammatory diseases,including cochlear *** distribution,number,and morphological characteristics of cochlear macrophages change significantly across different inner ear regions under various pathological conditions,including noise exposure,ototoxicity,and age-related ***,the exact mechanism underlying the role of mitochondria in macrophages in auditory function remains ***,we summarize the major factors and mitochondrial signaling pathways(e.g.,metabolism,mitochondrial reactive oxygen species,mitochondrial DNA,and the inflammasome)that influence macrophage activation in the innate immune *** particular,we focus on the properties of cochlear macrophages,activated signaling pathways,and the secretion of inflammatory cytokines after acoustic *** hope this review will provide new perspectives and a basis for future research on cochlear inflammation.

关键词： macrophage mitochondria Innate immunity Cochlea Infammation

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Number of J/ψ events at BESIII

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Chinese Physics C 2022年第7期46卷 74-84页

作者： m.Ablikim m.N.Achasov P.Adlarson S.Ahmed m.Albrecht R.Aliberti A.Amoroso m.R.An Q.An X.h.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban K.Begzsuren N.Berger m.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere h.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.Chelkov G.Chen h.S.Chen m.L.Chen S.J.Chen X.R.Chen Y.B.Chen Z.J.Chen W.S.Cheng G.Cibinetto F.Cossio J.J.Cui X.F.Cu h.L.Dai J.P.Dai X.C.Dai A.Dbeyssi R.E.de Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori Y.Ding C.Dong J.Dong L.Y.Dong m.Y.Dong X.Dong S.X.Du P.Egorov Y.L.Fan J.Fang S.S.Fang Y.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.h.Feng m.Fritsch C.D.Fu Y.Gao Y.Gao I.Garzia P.T.Ge C.Geng E.m.Gersabeck A Gilman K.Goetzen L.Gong W.X.Gong W.Gradl m.Greco L.m.Gu m.h.Gu C..Y.Guan A.Q.Guo A.Q.Guo L.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.han W.Y.han X.Q.hao F.A.harris K.K.he K.L.he F.h.heinsius C.h.heinz Y.K.heng C.herold m.himmelreich T.holtmann G.Y.hou Y.R.hou Z.L.hou h.m.hu J.F.hu T.hu Y.hu G.S.huang L.Q.huang X.T.huang Y.P.huang Z.huang T.hussain N husken W.Ikegami Andersson W.Imoehl m.Irshad S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.L.Ji Y.Y.Ji h.B.Jiang X.S.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin m.Q.Jing T.Johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert m.Kavatsyuk B.C.Ke I.K.Keshk A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.B.Kolcu B.Kopf m.Kuemmel m.Kuessner A.Kupsc m.G.Kurth W.Kuhn J.J.Lane J.S.Lange P.Larin A.Lavania L.Lavezzi Z.h.Lei h.Leithoff m.Lellmann T.Lenz C.Li C.h.Li Cheng Li D.m.Li F.Li G.Li h.Li h.Li h.B.Li h.J.Li h.N.Li J.L.Li J.Q.Li J.S.Li Ke Li L.K.Li Lei Li P.R.Li S.Y.Li W.D.Li W.G.Li X.h.Li X.L.Li Xiaoyu Li Z.Y.Li h.Liang h.Liang h.Liang Y.F.Liang Y.T.Liang G.R.Liao L.Z.Liao J.Libby A.Limphirat C.X.Lin D.X.Lin T.Lin B.J.Liu C.X.Liu D.Liu F.h.Liu Fang Liu Feng Liu G.m.Liu h.m.Liu huanhuan Liu huihui Liu J.B.Liu J.L.Liu J.Y.Liu K.Liu K.Y.Liu Ke Liu L.Liu m.h.Liu P.L.Liu Q.Liu Q.Liu S.B.Liu T.Liu T.Liu W.m.Liu X.Liu Y.Liu Y.B.Liu Z.A.Liu Z.Q.Liu X.C.Lou F.X.Lu h.J.Lu J.D. Institute of high Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Camnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.Budker Institute of Nuclear Physies SBRAS(BINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China hangzhou Normal University Hangzhou 310036China helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University of Science and Technology Luoyang 471003China henan University of Technology Zhengzhou 450001China huangshan College Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati I-00044FrascatiItaly INFN Sezione di Perugia I-06100PerugiaItaly University of Perugia I-06100PerugiaItaly University of Ferrara I-44122FerraraItaly Institute of modern Physics Lanzhou 730000China Institute of Physies and Technology Peace Ave 54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-Liebig-Universitaet Giessen Ⅱ.Physikaliches InstitutHeinricH-Buff-Ring 16D-35392 GiessenGermany Lanzhou University Lnzhou 730000China Liaoning Normal University Dalian 116029China Liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing Univ

Using inclusive decays of J/ψ aprecise determination of the number of J/ψ events collected with the BESIII detector was *** the two data sets taken in 2009 and 2012,the numbers of J/ψ events were recalculated to be(224.0±1.3)×10^(6) and(1088.5±4.4)×10^(6),respectively;these numbers are in good agreement with the previous measurements. For the J/ψ sample taken in 2017-2019,the number of events was determined to be(8774.0±39.4)×10^(6).The total number of J/ψ events collected with the BESIII detector was determined to be(10087±44)×10^(6),where the uncertainty is dominated by systematic effects,and the statistical uncertainty is negligible.

关键词： number of J/ψevents BESIII detector inclusive J/ψdecays

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RNA barcode segments for SARS-CoV-2 identification from hCoVs and SARSr-CoV-2 lineages

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Virologica Sinica 2024年第1期39卷 156-168页

作者： Changqiao You Shuai Jiang Yunyun Ding Shunxing ye Xiaoxiao Zou hongming Zhang Zeqi Li Fenglin Chen Yongliang Li Xingyi Ge Xinhong Guo College of Biology Hunan UniversityChangsha410082China College of Bioscience and Biotechnology Hunan Agricultural UniversityChangsha410128China

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the pathogen responsible for coronavirus disease 2019(COVID-19),continues to evolve,giving rise to more variants and global *** research has demonstrated that barcode segments can effectively and cost-efficiently identify specific species within closely related *** this study,we designed and tested RNA barcode segments based on genetic evolutionary relationships to facilitate the efficient and accurate identification of SARS-CoV-2 from extensive virus samples,including human coronaviruses(hCoVs)and SARSr-CoV-2 *** sequences sourced from NCBI and GISAID were meticulously selected and curated to construct training sets,encompassing 1733 complete genome sequences of hCoVs and SARSr-CoV-2 *** genetic-level species testing,we validated the accuracy and reliability of the barcode segments for identifying ***,75 main and subordinate species-specific barcode segments for SARS-CoV-2,located in ORF1ab,S,E,ORF7a,and N coding sequences,were intercepted and screened based on single-nucleotide polymorphism sites and weighted ***-testing,these segments exhibited high recall rates(nearly 100%),specificity(almost 30%at the nucleotide level),and precision(100%)performance on *** were eventually visualized using one and two-dimensional combined barcodes and deposited in an online database(http://***/).The successful integration of barcoding technology in SARS-CoV-2 identification provides valuable insights for future studies involving complete genome sequence polymorphism ***,this cost-effective and efficient identification approach also provides valuable reference for future research endeavors related to virus surveillance.

关键词： RNA barcode segments SARS-CoV-2 variants and related lineages hCoVs Genetic tests Complete genome sequences

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Observation of the Y(4230)and a new structure in e^(+)e^(-)→K^(+)K^(-)J/Ψ

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Chinese Physics C 2022年第11期46卷 7-21页

作者： m.Ablikim m.N.Achasov P.Adlarson m.Albrecht R.Aliberti A.Amoroso m.R.An Q.An X.h.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban V.Batozskaya D.Becker K.Begzsuren N.Berger m.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere A.Brueggemann h.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.Chelkov C.Chen G.Chen h.S.Chen m.L.Chen S.J.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Z.J.Chen W.S.Cheng X.Chu G.Cibinetto F.Cossio J.J.Cui h.L.Dai J.P.Dai A.Dbeyssi R.Ede Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori Y.Ding J.Dong L.Y.Dong m.Y.Dong X.Dong S.X.Du P.Egorov Y.L.Fan J.Fang S.S.Fang W.X.Fang Y.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.h.Feng K Fischer m.Fritsch C.Fritzsch C.D.Fu h.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge C.Geng E.m.Gersabeck A Gilman K.Goetzen L.Gong W.X.Gong W.Gradl m.Greco m.h.Gu C.Y Guan A.Q.Guo L.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.han W.Y.han X.Q.hao F.A.harris K.K.he K.L.he F.h.heinsius C.h.heinz Y.K.heng C.herold m.himmelreich T.holtmann G.Y.hou Y.R.hou Z.L.hou h.m.hu J.F.hu T.hu Y.hu G.S.huang K.X.huang L.Q.huang L.Q.huang X.T.huang Y.P.huang Z.huang T.hussain N husken W.Imoehl m.Irshad J.Jackson S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.L.Ji Y.Y.Ji Z.K.Jia h.B.Jiang S.S.Jiang X.S.Jiang Y.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin m.Q.Jing T.Johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert m.Kavatsyuk B.C.Ke I.K.Keshk A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.B.Kolcu B.Kopf m.Kuemmel m.Kuessner A.Kupsc W.Kuhn J.J.Lane J.S.Lange P.Larin A.Lavania L.Lavezzi Z.h.Lei h.Leithoff m.Lellmann T.Lenz C.Li C.Li C.h.Li Cheng Li D.m.Li F.Li G.Li h.Li h.Li h.B.Li h.J.Li h.N.Li J.Q.Li J.S.Li J.W.Li Ke Li L.J Li L.K.Li Lei Li m.h.Li P.R.Li S.X.Li S.Y.Li T.Li W.D.Li W.G.Li X.h.Li X.L.Li Xiaoyu Li Z.Y.Li h.Liang h.Liang h.Liang Y.F.Liang Y.T.Liang G.R.Liao L.Z.Liao J.Libby A.Limphirat C.X.Lin D.X.Lin T.Lin B.J.Liu C.X.Liu D.Liu F.h.Liu Fang Liu Feng Liu G.m.Liu h.Liu h.m.Liu huanhuan Liu huihui Liu J.B.Liu J.L.Liu J.Y.Liu K.Liu K.Y.L Institute of high Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China hangzhou Normal University Hangzhou 310036China helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University of Science and Technology Luoyang 471003China henan University of Technology Zhengzhou 450001China huangshan College Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Institute of modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-Liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16

The cross sections of e^(+)e^(-)→K^(+)K^(-)J/Ψat center-of-mass energies from 4.127 to 4.600 GeV are measured based on 15.6 fb-1data collected with the BESⅢ detector operating at the BEPCⅡ storage *** resonant structures are observed in the line shape of the cross *** mass and width of the first structure are measured to be(4225.3±2.3±21.5)meV and(72.9±6.1±30.8)meV,*** are consistent with those of the established Y(4230).The second structure is observed for the first time with a statistical significance greater than 8σ,denoted as Y(4500).Its mass and width are determined to be(4484.7±13.3±24.1)meV and(111.1±30.1±15.2)meV,*** first presented uncertainties are statistical and the second ones are *** product of the electronic partial width with the decay branching fractionΓ(Y(4230)→e^(+)e^(−))B(Y(4230)→K^(+)K^(−)J/Ψ)is reported.

关键词： Y states charmonium-like states BESⅢ

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