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Prescribing patterns of antibiotics at two teaching hospitals in Sanandaj

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海南医学院学报 2010年第2期16卷 150-153页

作者： Beiranvand S mostafavi S Tamimi m Shahsavari S m.h.mmadi h Ghotbi N Kalantar E Deputy of Food and Drug Kurdistan University of Medical Sciences Kurdistan Digestive Research Center Tohid HospitalKurdistan University of Medical Sciences Department of health School of HealthKurdistan University of Medical Sciences Evaluation Unit Deputy of HealthKurdistan University of Medical Sciences Department of Pediatrics Beasat hospitalKurdistan University of Medical Sciences

We report here the results of a prospective analysis of the pattern of antibiotics use over a one month period(may 2009)at two teaching hospitals in Sanandaj,western part of *** on antibiotic usage were obtained from the pharmacy *** was coded,computed and analyzed using SPSS version 11.5.A total of 1336 and 556 patients from Beasat and Tohid hospital respectively received *** patients represented 758(41.5 %)and females 1080(58.5 %)of the total number of patients evaluated by physicians at the two hospitals during the one month *** of antibiotics varied from.h.spital to hospital;Beasat hospital had the highest *** ward-wise distribution of antibiotic use showed that the prevalence of prescribing was highest in the post partum ward(66.58%).Similarly,among Tohid hospital wards,men surgical ward and women surgical ward prescribed antibiotics significantly more than all other *** route of administration of antibiotics was parentrally for 85.5% and 88.2% at Beasat anf Tohid hospitals *** distribution of use of individual antibiotics showed that cepfzoline was the most frequently prescribed antibiotics used at both the ***(childbirth)and pneumonia were the most frequent diagnosed pattern for which an antibiotic was prescribed at Beasat and Tohid hospital *** conclusion our study suggests that there is considerable scope for improving prescribing pattern among the practitioners and minimizing the use of *** improvement would be facilitated by providing feedback,prescriber education and hospital formulary.

关键词：抗生素合理用药患病率医院

Low dose oral haloperidol does not prolong QTc interval in older acutely hospitalised adults： a subanalysis of a randomised double-blind placebo-controlled study

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Journal of Geriatric Cardiology 2018年第6期15卷 401-407页

作者： Edmee Jm Schrijver maaike Verstraaten Peter m van de Ven Pierre m Bet Astrid m van Strien Carel de Cock Prabath WB Nanayakkara on behalf of all hARPOON Investigators Department of Internal medicine VU University Medical Centre Amsterdam the Netherlands Department of Cardiology VU University Medical Centre Amsterdam the Netherlands Department of Epidemiology and Biostatistics VU University Medical Centre the Netherlands Department of Clinical Pharmacology and Pharmacy VU University Medical Centre the Netherlands Department of Geriatric medicine Jeroen Bosch Hospital s-Hertogenbosch the Netherlands

Background haloperidol is the most frequently prescribed antipsycbotic for delirium symptoms. The risk of QTc prolongation often raises concerns, although the effect of haloperidol on QTc interval has not yet been investigated in a randomised placebo-controlled fixed-dose study. methods A subanalysis of a randomised double-blind placebo-controlled study was conducted to evaluate the effect of prophylactic haloperidol 1 mg or placebo 1 mg orally twice-daily （maximum of 14 doses） on QTc interval in patients aged 70 years and over. Bedside, 12-lead ECGs were recorded before, during and after the one-week intervention period. Automatic QTc measurements were ob- tained in addition to manual measurements of QT and RR intervals, blinded for treatment status. manual measurements were corrected （QTc） using Bazett （QTc-B）, Framingham （QTc-Fa）, Fridericia （QTc-Fi） and hodges （QTc-h） methods. mixed model analyses were used to test for differences in longitudinal course of QTc between patients receiving haloperidol and placebo. Results ECG recordings of 72 patients （haloperidol n = 38） were analysed, 45.8% male. median （range） haloperidol serum concentration on day 4 was 0.71 （0.32-1.82） μg/L （n = 23）. Longitudinal course of mean QTc did not significantly differ between treatment arms for any of the automatic or manually derived QTc values. Conclusions Low dose oral haloperidol did not result in QTc prolongation in older acutely hospitalised patients. Results may not be generalizable to patients with existing ECG abnormalities such as atrial fibrillation.

关键词： haloperidol Prolongation QTc interval The aged

membrane Fouling in microfiltration of Sanitary Landfill Leachate for Removals of Colourand Solids

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应用与环境生物学报 2013年第1期19卷 184-188页

作者： Emad S.m.Ameen Water Research Alliance Institute of Environmental and Water Resource ManagementFaculty of Civil EngineeringUniversiti Teknologi Malaysia

In this research,the treatability of solids from sanitary landfill leachate by microfiltration membrane was investigated and the fouling of the membrane was carefully *** microfiltration process was carried out for 21 h in experimental system involved coagulation with moringa oleifera followed by filtration using submerged hollow fibre microfiltration membrane (mFm).Coagulation with ***,air diffusers and back flush technique were used for preventing or alleviating fouling of the *** hollow fibre mFm showed high removals of 98%,91% and 99% for turbidity,colour and total suspended solids *** was obtained at the beginning of the ***,quality of the filtrate rapidly declined during the filtration *** was found to proceed according to the classical cake filtration *** with *** as well as the back-flush technique could not fully restore the deterioration occurred to the membrane.

关键词： RAPD ISSR AFLP 环境生物学

Improvement of porous polyvinylidene fluoride-co-hexafluropropylene hollow fiber membranes for sweeping gas membrane distillation of ethylene glycol solution

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Chinese Journal of Chemical Engineering 2020年第12期28卷 3002-3010页

作者： m.Ajdar A.Azdarpour A.mansourizadeh B.honarvar Department of Chemical Engineering Marvdasht BranchIslamic Azad UniversityMarvdashtIran Department of Chemical Engineering Membranne Science and Technology Research Center(MSTRC)Gachsaran BranchIslamic Azad UniversityGachsaranIran Department of Civil Engineering The University of Texas at ArlingtonArlingtonTX 76019USA

Porous polyvinylidene fluoride-co-hexafluropropylene(PVDF-hFP)hollow fiber membranes were fabricated through a wet spinning *** order to improve the membrane structure,composition of the polymer solution was adjusted by studying ternary phase diagrams of polymer/solvent/*** prepared membranes were used for sweeping gas membrane distillation(SGmD)of 20 wt% ethylene glycol(EG)aqueous *** membranes were characterized by different tests such as N2 permeation,overall porosity,critical water entry pressure(CEPw),water contact angle and collapsing *** FESEm examination,addition of 3 wt% glycerol in the PVDF-hFP solution,produced membranes with smaller finger-likes cavities,higher surface porosity and smaller pore *** the polymer concentration up to 21 wt% resulted in a dense spongy structure which could significantly reduce the N2 *** membrane prepared by 3 wt% glycerol and 17 wt% polymer demonstrated an improved structure with mean pore size of 18 nm and a high surface porosity of 872 m^−*** of 350 kPa and overall porosity of 84% were also obtained for the improved *** pressure of the membranes relatively improved by increasing the polymer *** the SGmDtest,the developed membrane represented a maximumpermeate flux of 28 kg·m^−2·h^−1 which is almost 19% higher than the flux of plain *** 120 h of a long-termSGmD operation,a gradual flux reduction of 30% was *** addition,EG rejection reduced from 100% to around 99.5% during 120 h of the operation.

关键词： PVDF-hFP hollow fiber membrane Ternary phase diagram membrane characterization Sweeping gas membrane distillation Ethylene glycol

Tailoring the optical and magnetic properties of La-Bam.h.xaferrites by Ni substitution

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Chinese Physics B 2022年第2期31卷 570-575页

作者： hafiz T.Ali mRamzan m Imran Arshad Nicola A.morley m.h.ssan Abbas m.h.mmad Yusuf Atta Ur Rehman Khalid m.h.ood Adnan Ali Nasir Amin mAjaz-un-Nabi Department of mechanical Engineering College of EngineeringTaif UniversityTaif 21944Saudi Arabia Department of Physics Government College UniversityFaisalabadPakistan Department of materials Science and Engineering University of SheffieldSir Robert Hadfield BuildingMapping St.SheffieldS13JDUK Department of Clinical Pharmacy College of PharmacyTaif UniversityTaif 21944Saudi Arabia

We investigate the impact of Ni insertion on the structural,optical,and magnetic properties of Ba_(0.8)La_(0.2)Fe_(12-x)Ni_(x)O_(19)hexaferrites(Ni substituted La-Bam.h.xaferrites).Samples were prepared using the conventional co-precipitation method and sintered at 1000℃for 4 hours to assist the crystallization *** analysis of the structure of the samples was carried out using an x-ray diffraction(XRD)*** m-type hexagonal structure of all the samples was confirmed using XRD *** lattice parameters a and c were found to be in the ranges of 5.8925±0.001 nm–5.8952±0.001 nm and 23.2123±0.001 nm–23.2219±0.001 nm,*** m-type hexagonal nature of the prepared samples was also indicated by the presence of corresponding FT-IR bands and Raman modes in the FT-IR and Raman spectra,*** results confirmed the successful synthesis of the samples according to the required stoichiometric ratio.A UV-vis spectrometer was used to record the absorption spectra of the prepared samples in the wavelength range of 200 nm–1100 *** optical energy bandgap of the samples was found to be in the range of 1.21 eV–3.39 *** m.h.loops of the samples were measured at room temperature at an applied magnetic field range of 0 kOe–60 kOe.A high saturation magnetization of 99.92 emu/g was recorded in the sample with x=0 at a microwave operating frequency of 22.2 *** high value of saturation magnetization is due to the substitution of La3+ions at the spin-up(12k,2a,and 2b)*** Ni substitution is proven to be a potential candidate for the tuning of the optical and magnetic parameters of m-type ***,we suggest that the prepared samples are suitable for use in magneto-optic applications.

关键词： m-type hexaferrite nanostructured materials magnetic properties optical properties

A dynamic range extension system for LhAASOWCDA-1

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Radiation Detection Technology and methods 2021年第4期5卷 520-530页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.W.Bao D.Bastieri X.J.Bi Y.J.Bi h.Cai J.T.Cai Z.Cao Z.Cao J.Chang J.F.Chang X.C.Chang B.m.Chen J.Chen L.Chen L.Chen L.Chen m.J.Chen m.L.Chen Q.h.Chen S.h.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.W.Cui X.h.Cui Y.D.Cui B.Z.Dai h.L.Dai Z.G.Dai Danzengluobu D.della Volpe B.D’Ettorre Piazzoli X.J.Dong J.h.Fan Y.Z.Fan Z.X.Fan J.Fang K.Fang C.F.Feng L.Feng S.h.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao W.Gao m.m.Ge L.S.Geng G.h.Gong Q.B.Gou m.h.Gu J.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.han h.h.he h.N.he J.C.he S.L.he X.B.he Y.he m.h.ller Y.K.hor C.hou X.hou h.B.hu S.hu S.C.hu X.J.hu D.h.huang Q.L.huang W.h.huang X.T.huang Y.huang Z.C.huang F.Ji X.L.Ji h.Y.Jia K.Jiang Z.J.Jiang C.Jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li h.B.Li h.C.Li h.Y.Li J.Li K.Li W.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.W.Liang Y.F.Liang S.J.Lin B.Liu C.Liu D.Liu h.Liu h.D.Liu J.Liu J.L.Liu J.S.Liu J.Y.Liu m.Y.Liu R.Y.Liu S.m.Liu W.Liu Y.N.Liu Z.X.Liu W.J.Long R.Lu h.K.Lv B.Q.ma L.L.ma X.h.ma J.R.mao A.masood W.mitthumsiri T.montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei m.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Sheng J.R.Shi h.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.h.T.Tam Z.B.Tang W.W.Tian B.D.Wang C.Wang h.Wang h.G.Wang J.C.Wang J.S.Wang L.P.Wang L.Y.Wang R.N.Wang W.Wang W.Wang X.G.Wang X.J.Wang X.Y.Wang Y.D.Wang Y.J.Wang Y.P.Wang Z.Wang Z.Wang Z.h.Wang Z.X.Wang D.m.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu h.R.Wu S.Wu W.X.Wu X.F.Wu S.Q.Xi J.Xia J.J.Xia G.m.Xiang G.Xiao h.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.h.Yan C.W.Yang F.F.Yang J.Y.Yang L.L.Yang m.J.Yang R.Z.Yang S.B.Yang Y.h.Yao Z.G.Yao Y.m.Ye L.Q.Yin N.Yin X.h.You Z.Y.You Y.h.Yu Q.Yuan h.D.Zeng T.X.Zeng W.Zeng Z.K.Zeng m.Zha X.X.Zhai B.B.Zhang h.m.Zhang h.Y.Zhang J.L.Zhang J.W.Zhang L.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao J.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou h.Zhou J.N.Zhou Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics BeijingChina University of Science and Technology of China Hefei 230026AnhuiChina Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhou 510006GuangdongChina School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhai 519000GuangdongChina School of Physical Science and Technology Guangxi UniversityNanning 530004GuangxiChina hebei Normal University Shijiazhuang 050024HebeiChina School of Physics and microelectronics Zhengzhou UniversityZhengzhou 450001HenanChina School of Astronomy and Space Science Nanjing UniversityNanjing 210023JiangsuChina Key Laboratory of Dark matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023JiangsuChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237ShandongChina Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031SichuanChina College of Physics Sichuan UniversityChengdu 610065SichuanChina Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina School of Physics

Purpose The main scientific goal of LhAASO-WCDA is to survey gamma-ray sources with energy from 100 GeV to 30 *** observe high-energy shower events,especially to measure the energy spectrum of cosmic rays from 100 TeV to 10 PeV,a dynamic range extension system(WCDA++)is designed to use a 1.5-inch PmT with a dynamic range of four orders of magnitude for each cell in *** The dynamic range is extended by using these PmTs to measure the effective charge density in the core region of air shower events,which is an important parameter for identifying the composition of primary *** and Conclusion The system.h.s been running for more than one *** this paper,the details of the design and performance of WCDA++are presented.

关键词： LhAASO-WCDA WCDA++ Water Cherenkov detector Performance

伊通上地幔剪切带捕虏体中富铝尖晶石的地球化学特征

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吉林大学学报（地球科学版） 2006年第4期36卷 497-502页

作者：贾大成邢立新潘军 m.J.van Bergen h.van Roermund 吉林大学地球探测科学与技术学院长春130026 乌特勒支大学地球科学系

伊通上地幔剪切带中辉石岩、二辉橄榄岩和易剥橄榄岩是3个主要地幔捕虏体,其中尖晶石的化学成分以富铝为特征。辉石岩中尖晶石在薄片下呈绿色,为铝含量高、铬含量低的铝尖晶石;与之相比,二辉橄榄岩和易剥橄榄岩中尖晶石在薄片下呈棕色,... 详细信息

伊通上地幔剪切带中辉石岩、二辉橄榄岩和易剥橄榄岩是3个主要地幔捕虏体,其中尖晶石的化学成分以富铝为特征。辉石岩中尖晶石在薄片下呈绿色,为铝含量高、铬含量低的铝尖晶石;与之相比,二辉橄榄岩和易剥橄榄岩中尖晶石在薄片下呈棕色,为铝含量相对较低、铬含量相对较高的富铝铬尖晶石。尖晶石的颜色与Al、mg、Cr、Fe含量有关。在不同捕虏体中尖晶石成分具有不同的变化范围,尖晶石化学成分之间存在一定的相关性,mg#与Cr#,mg#与Fe2+和Cr与Al呈现负相关性,而mg#与Al#呈现出正相关性,反映不同捕虏体中尖晶石具有同一来源和成因联系。在地幔岩石部分熔融和结晶过程中Cr和Al的分异明显。固溶体条件下基本服从八面体Cr Al替代关系,而不同地幔捕虏体中尖晶石的成分差异是岩浆部分熔融和结晶过程中元素分异、固溶体离子替代的结果。

关键词：富铝尖晶石成分元素分异相关性

Anticancer property of sediment actinomycetes against mCF-7 and mDA-mB-231 cell lines

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Asian Pacific Journal of Tropical Biomedicine 2012年第2期2卷 92-96页

作者： Ravikumar S Fredimoses m Gnanadesigan m School of marine Sciences Department of Oceanography and Coastal Area StudiesAlagappa UniversityThondi CampusThondi-623 409Ramanathapuram District Department of Biotechnology K.S.Rangasamy College of Arts & ScienceThiruchengodu- 637209Namakkal District

ObjectiveTo investigate the anticancer property of marine sediment actinomycetes against two different breast cancer cell *** vitro anticancer activity was carried out against breast (mCF-7 and mDA-mB-231) cancer cell lines. Partial sequences of the 16s rRNA gene, phylogenetic tree construction, multiple sequence analysis and secondary structure analysis were also carried out with the actinomycetes *** the selected five actinomycete isolates, ACT01 and ACT02 showed the IC50 value with (10.13±0.92) and (22.34±5.82) μg/mL concentrations, respectively for mCF-7 cell line at 48 h, but ACT01 showed the minimum (18.54±2.49 μg/mL) level of IC50 value with mDA-mB-231 cell line. Further, the 16s rRNA partial sequences of ACT01, ACT02, ACT03, ACT04 and ACT05 isolates were also deposited in NCBI data bank with the accession numbers of GQ478246, GQ478247, GQ478248, GQ478249 and GQ478250, respectively. The phylogenetic tree analysis showed that, the isolates of ACT02 and ACT03 were represented in group I and III, respectively, but ACT01 and ACT02 were represented in group II. The multiple sequence alignment of the actinomycete isolates showed that, the maximum identical conserved regions were identified with the nucleotide regions of 125 to 221st base pairs, 65 to 119th base pairs and 55, 48 and 31st base pairs. Secondary structure prediction of the 16s rRNA showed that, the maximum free energy was consumed with ACT03 isolate (-45.4 kkal/mol) and the minimum free energy was consumed with ACT04 isolate (?7.6 kkal/mol).ConclusionsThe actinomycete isolates of ACT01 and ACT02 (GQ478246 and GQ478247) which are isolated from sediment sample can be further used as anticancer agents against breast cancer cell lines.

关键词： Actinomycetes Breast cancer mCF–7 mDA–mB–231 Phylogenetic tree Anticancer property multiple sequence analysis Secondary structure analysis Sediment Anticaner agent Cell line

highly efficient GaAs solar cells by limiting light emission angle

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Light(Science & Applications) 2013年第1期2卷 236-241页

作者： Emily D Kosten Jackson h Atwater James Parsons Albert Polman harry A Atwater Thomas J.Watson Laboratories of Applied Physics California Institute of TechnologyPasadenaCA 91125 USA Center for Nanophotonics FOM-Institute AMOLFScience Park 1041098XG AmsterdamThe Netherlands

In a conventional flat plate solar cell under direct sunlight,light is received from the solar disk,but is re-emitted *** isotropic emission corresponds to a significant entropy increase in the solar cell,with a corresponding drop in ***,using a detailed balance model,we show that limiting the emission angle of a high-quality GaAs solar cell is a feasible route to achieving power conversion efficiencies above 38%with a single *** highest efficiencies are predicted for a thin,light trapping cell with an ideal back reflector,though the scheme is robust to a non-ideal back *** with a conventional planar cell geometry illustrates that limiting emission angle in a light trapping geometry not only allows for much thinner cells,but also for significantly higher overall efficiencies with an excellent rear ***,we present ray-tracing and detailed balance analysis of two angular coupler designs,show that significant efficiency improvements are possible with these couplers,and demonstrate initial fabrication of one coupler design.

关键词： detailed balance GaAs solar cell light trapping photovoltaics two photon lithography