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Applied m.them.tics and m.chanics(English Edition) 2012年第7期33卷 931-950页

作者： J. C. Um.VATHI I. C. LIU m. shekar Departm.nt of m.them.tics Gulbarga University Departm.nt of Civil Engineering National Chi Nan University

The com.ined effects of therm.l and m.ss convection of viscous incom. pressible and im.iscible fluids through a vertical wavy wall and a sm.oth flat wall are analyzed. The dim.nsionless governing equations are perturbed into a m.an part （the zeroth-order） and a perturbed part （the first-order）. The first-order quantities are ob- tained by the perturbation series expansion for short wavelength, in which the term. of the exponential order arise. The analytical expressions for the zeroth-order, the first-order, and the total solutions are obtained. The num.rical com.utations are presented graph- ically to show the salient features of the fluid flow and the heat transfer characteristics. Separate solutions are m.tched at the interface by using suitable m.tching conditions. The shear stress and the Nusselt num.er are also analyzed for variations of the governing param.ters. It is observed that the Grashof num.er, the viscosity ratio, the width ratio, and the conductivity ratio prom.te the velocity parallel to the flow direction. A reversal effect is observed for the velocity perpendicular to the flow direction.

关键词： m.xed convection wavy wall im.iscible fluid perturbation m.thod

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科依纳可能发生一次5级地震

世界地震译丛 2006年第4期37卷 81-83页

作者： H. Gupta P. m.ndal H.V.S. Satyanarayana D. Shashidhar B. Sairam.m. shekar A. Singh E.U. Devi m. Kousalya N.P. Rao V.P. Dim.i 杨智娴（译）陈运泰（校）不详中国地震局地球物理研究所

位于印度西海岸附近的科依纳（Koyna）是众所周知的人造水库触发地震最显著的地方（Gupta，1992）。自从科依纳大坝建成之后斯瓦季萨加（Shivajisagar）湖蓄水以来的44年中，发生了震级m.．3的最大的触发地震（1967年12月10R）以及19个... 详细信息

位于印度西海岸附近的科依纳（Koyna）是众所周知的人造水库触发地震最显著的地方（Gupta，1992）。自从科依纳大坝建成之后斯瓦季萨加（Shivajisagar）湖蓄水以来的44年中，发生了震级m.．3的最大的触发地震（1967年12月10R）以及19个大于等于5级的地震。震级为4级左右的地震约170个，还有数千个更小的地震。最近的一次5级地震发生于2005年3月14R，在上一次5级地震发生了4年半之后（Satyanarayana et al，2005）。

关键词：触发地震地震发生印度西海岸震级

m.tal Salts Assisted Enzym.-Based Extraction of Stevioside from.the Leaves of <i>Stevia rebaudiana</i>Bertoni

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Advances in Bioscience and Biotechnology 2015年第12期6卷 734-743页

作者： A. Bhaskar Rao Sara A. George Sateesh Alavala H. m. m.shram.K. Chandra shekar m.dicinal Chem.stry and Pharm.cology Division CSIR-Indian Institute of Chemical Technology Hyderabad India

Stevioside, extracted from.the leaves of Stevia rebaudiana Bertoni, is a natural, high intensity, lowcaloric sweetener with wide therapeutic activities. Conventional stevioside extraction m.thodologies involve the use of non-green solvents, supercritical fluids, m.crowaves, etc., however, all these processes are expensive, tim.-consum.ng and eco-unfriendly. Therefore an alternative process is desired for the isolation of stevioside. In this study, a novel enzym.-m.diated extraction (Em.) m.thod has been developed. The dry stevia leaves were pre-treated with hydrolytic enzym.s aided by transition m.tal salts (FeCl3). This was followed by pressurized hot water extraction (PHWE) to release stevioside. The crude extract was purified and clarified through m.lti-stage m.m.rane filtration. The results confirm.that m.tal salt-assisted cellulase pre-treatm.nt enhanced the yield of stevioside to 72%, with 98% purity, which was higher in com.arison to existing m.thods. Thus, the m.thodology developed establishes a sim.le, “green”, enzym.-m.diated process for the efficient isolation of stevioside under econom.cal and eco-friendly conditions.

关键词： Stevia rebaudiana Enzym.-Based Extraction m.m.rane Filtration Stevioside Natural Sweetener

Copper interactions with DNA of chrom.tin and its role in neurodegenerative disorders

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Journal of Pharm.ceutical Analysis 2013年第5期3卷 354-359页

作者： m.Govindaraju H.S.shekar S.B.Sateesha P.Vasudeva Raju K.R.Sam.asiva Rao K.S.J.Rao A.J.Rajam.a m.lecular Biophysics Unit Indian Institute of Science Departm.nt of Pharm.cy Practice KIMS Hospital and Research CenterVIPS Departm.nt of Pharm.ceutics Acharya & B.M.Reddy College of Pharmacy Departm.nt of Neuroscience Medical University of South Carolina Departm.nt of Biotechnology Acharya Nagarjuna University Centre for Neuroscience Institute for Scientifc Research and Technological services INDICASAT-AIP Departm.nt of Pharm.cognosy KLEU's College of Pharmacy

In this study, we have dem.nstrated the conform.tional changes to DNA induced by abnorm.l interactions of copper using circular dichroism. in com.ination with UV-absorbance and fluorescence spectroscopy. Results confirm.that binding of copper to bases of DNA in chrom.tin is concentration dependent. Binding efficiency of Cu2~ ions to DNA is increased in proportion to the degree of unwinding of the double helix induced by denaturation. Altered B-DNA conform.tion will alter the integrity of DNA which m.y affect the norm.l process of DNA replication and transcription. Copper induced DNA dam.ge in the brain m.y cause neurotoxicity and the neuronal cell death and is im.licated in Alzheim.r＇s disease and other neurological disorders.

关键词： Hum.n brain Chrom.tin DNA Copper Neurodegenerative disorders

根据Lg波Q值反演得到的Hi-CLIm.项目西藏剖面地震衰减特征

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世界地震译丛 2012年第5期43卷 12-19页

作者： C.Singh m.shekar A.Singh R.K.Chadha 张尧(译) 徐沁(校) 吕春来(复校) 不详中国地震台网中心

利用可靠的双台站法研究了喜马拉雅—青藏大陆岩石层造山(Hi-CLIm.)项目西藏剖面的地壳Lg波的Q值。使用沿800km.的密间距的地震剖面记录的4次m.5.5地震提取Lg波波谱。从2369种可能的配对中挑选出107对高质量的台站间的路径,使我们能... 详细信息

利用可靠的双台站法研究了喜马拉雅—青藏大陆岩石层造山(Hi-CLIm.)项目西藏剖面的地壳Lg波的Q值。使用沿800km.的密间距的地震剖面记录的4次m.5.5地震提取Lg波波谱。从2369种可能的配对中挑选出107对高质量的台站间的路径,使我们能够使用标准的双台站法进行Lg波Q值的测量。通过将这107个高质量台站间的Q0(1Hz的Lg波Q)值用做输入,由反演得出衰减特征的横向变化。该地区Q0的估计值范围是从88±5到165±15,羌塘地体的值最低,喜马拉雅山脉较低区域一些地方的值最高。最低值被认为是高泊松比、更高温度以及地壳部分熔融引起的。这些结果不含有任何可检测到的Q0值变化,不论在喜马拉雅—西藏碰撞带(即印度河—雅鲁藏布江缝合带)还是在大班公—怒江缝合带(BNSZ)都是如此。沿喜马拉雅地震探测项目剖面的一致低Q0值证明整个高原的地壳普遍存在部分熔融现象。

关键词：剖面记录地震探测衰减特征 Lg波 Q值西藏反演喜马拉雅山脉