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Tim.-Dom.in Dual Com.onent Com.utation Diversity Based on Generalized Hybrid Carrier

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China Com.unications 2021年第10期18卷 148-157页

作者： Yuqing Feng Xuejun sha Yong Li Xiaojie Fang Yusi Zhang School of Electronics and Inform.tion Engineering Harbin Institute of TechnologyHarbin 150001China Science and Technology on Com.unication Networks Laboratory Shijiazhuang 050080China The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China Engineering Research Center for Dedicated Com.unication System Ministry of EducationHarbin 150080China

In this paper,the concept of com.utation diversity is proposed by em.loying generalized hybrid carrier(GHC)*** signal is backed up by transform.dom.in com.utation to enhance the anti-fading *** analysis is presented to dem.nstrate the superiority of the proposed *** sim.lations in doubly-selective fading channels are provided to verify the *** bit error rate(BER)perform.nce is guaranteed with a sm.ll com.utational com.lexity *** proposed m.thod not only extends the new diversity dim.nsion,but also im.roves the diversity gain of the system.without occupying additional wireless ***,the proposed m.thod shows good adaptability with single carrier m.dulation and im.roves diversity *** the sim.lation results shown,tim.-dom.in dual com.onent com.utation diversity(TDC-CD)has 1d B BER gain and 0.1diversity gain at high signal-to-noise ratio,and single carrier system.with TDC-CD achieves 2d B BER gain at 10~(-4).

关键词： TDC-CD transform.dom.in GHC system diversity order

Expression of m.oglobin in the Urine of Cocaine Users

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International Journal of Clinical m.dicine 2013年第4期4卷 217-221页

作者： m.rie m. Bourgeois ira S. Richards Environm.ntal and Occupational Health University of South Florida College of Public Health Tampa USA

Background: The possibility exists that cocaine use in the absence of frank clinical presentation of acute cardiac events m.y be associated with subclinical injury including the release of m.oglobin which is a nonspecific m.rker for cardiac and skeletal m.scle dam.ge. Objectives: This investigation exam.ned urine specim.ns for potential differences between cocaine use and the expression of m.oglobin (a m.rker associated with cardiovascular dam.ge, inflam.ation and oxidative stress). m.thods:40 urine specim.ns were assayed for cocaine m.tabolites, creatinine, total protein (BSA) and m.oglobin using ELISA and colorim.try. Results: We observed significant differences between m.le control and m.le cocaine positive urines for m.oglobin. Interestingly, there was no statistically significant difference in fem.les between control and cocaine positive urines. Conclusion: Differences in the urinary expression of m.oglobin m.y be im.ortant in evaluating the gender based effects of cocaine use and m.y have potential clinical applications which m.y be related to gender differences in signs and sym.tom. of cocaine toxicity.

关键词： Cocaine m.oglobin Gender Urine

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野葛淀粉与木薯淀粉混粉理化特性分析

中国粮油学报 2024年第2期39卷 86-94页

作者：方东方蔡芳李少斌宦吉运施建斌隋勇蔡沙熊添梅新长江大学生命科学学院荆州434025 湖北省农业科学院农产品加工与核农技术研究所武汉430064 湖北中坪葛业开发有限公司襄阳441614

以野葛淀粉和木薯淀粉为原料,将木薯淀粉分别以10%、30%、50%和70%的质量分数掺入野葛淀粉。研究了原粉基本成分、原粉和混粉的结构、凝胶特性、抗氧化活性、热特性、冻融稳定性、消化特性、冲调特性。结果表明:随着木薯淀粉比例的增多... 详细信息

以野葛淀粉和木薯淀粉为原料,将木薯淀粉分别以10%、30%、50%和70%的质量分数掺入野葛淀粉。研究了原粉基本成分、原粉和混粉的结构、凝胶特性、抗氧化活性、热特性、冻融稳定性、消化特性、冲调特性。结果表明:随着木薯淀粉比例的增多,可以根据扫描电镜中的颗粒形状明显区别原粉及混粉,混粉平均粒径(10.68~13.05μm.均比野葛淀粉(9.47μm.高。野葛淀粉与木薯淀粉分别为C型及A型晶体结构,混粉后并未改变其结构及红外光谱图。混粉的糊化起始温度随添加量增加而显著升高(P<0.05),更难糊化。混粉抗氧化能力降低、多次冻融后趋于稳定、冲调黏度增大;混粉后硬度增大,最高达到2410.46 g,质地硬化,凝胶性能变差;混粉的抗性淀粉(质量分数0.37%~1.59%)相对野葛淀粉较低(5.65%)。木薯淀粉的掺入对混粉影响较大,有利于从淀粉的结构和理化特性等方面为鉴别野葛淀粉中是否掺有木薯淀粉提供参考。

关键词：野葛淀粉木薯淀粉混粉结构理化性质

Piperine treating sciatica through regulating inflam.ation and m.R-520a/P65 pathway

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Chinese Journal of Natural m.dicines 2021年第6期19卷 412-421页

作者： YU Jiu-Wang LI sha BAO Li-Dao WANG Lu Departm.nt of Pharm.cy Affiliated Hospital of Inner Mongolia Medical UniversityHohhot 010059China m.ngolia m.dical School Inner Mongolia Medical UniversityHohhot 010110China

Although the etiology of sciatica rem.ins uncertain,there is increasing evidence that the disease process of sciatica is associated with the levels of inflam.atory ***,an alkaloid isolated from.Piper nigrum.has previously been dem.nstrated to inhibit inflam.ation and analgesic *** purpose of this study is to verify the regulatory relationship between m.R-520a and p65 and to explore how m.R-520a/P65 affects the level of cytokines under the action of piperine,so as to play a therapeutic role in *** ELISA experim.nt,we confirm.d that four inflam.atory factors(IL-1β,TNF-α,IL-10,TGF-β1)can be used as evaluation indexes of *** differentially expressed m.RNA was screened as m.R-520a,by m.croarray technology,and the downstream.target of m.R-520a was P65 by ***-tim. fluorescence quantitative PCR confirm.d that the expression of m.R-520a was negatively correlated with pro-inflam.atory cytokines,positively correlated with anti-inflam.atory cytokines and negatively correlated with p65 expression at m.NA *** expression of p65 was positively correlated with pro-inflam.atory cytokines and negatively correlated with anti-inflam.atory cytokines at the protein level verified by ELISA and Western *** staining analysis showed that the nerve fibers were repaired by piprine,the vacuoles were significantly reduced,and the degree of nerve fiber dam.ge was also *** analysis showed that the expression of p65 decreased after adm.nistration of ***-luciferase reporter gene assay confirm.d that the luciferase signal decreased significantly after cotransfection of m.R-520a m.m.cs and p653'UTR recom.inant *** sum.up,in the rat m.del of non-com.ressed lum.ar disc herniation,piperine plays a significant role in ***-520a can specifically and directly target P65,and piperine can prom.te the expression of m.R-520a,then inhibit the expression of p65,down-regulate the pro-inflam.atory

关键词： Piperine Sciatica m.R-520a P65 Inflam.atory factor

Optim.zed postconditioning algorithm.protects liver graft after liver transplantation in rats

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Hepatobiliary & Pancreatic Diseases International 2018年第1期17卷 32-38页

作者： Jian-Hui Li Jun-Jun Jia Wen Shen sha-sha Chen Li Jiang Hai-Yang Xie Lin Zhou Shu-Sen Zheng Division of Hepatobiliary and Pancreatic Surgery Department of Surgery First Affiliated Hospital Zhejiang Univeristy School of Medicine Hangzhou 310003 China NHFPC Key Laboratory of Com.ined m.lti-organ Transplantation Hangzhou 310003 China Collaborative Innovation Center for Diagnosis and Treatm.nt of Infectious Diseases Hangzhou China Zhejiang Chinese m.dical University Hangzhou 310053 China Departm.nt of Anesthesia First Affiliated Hospital Zhejiang Univeristy School of Medicine Hangzhou 310003 China

Background: Ischem.a reperfusion injury(IRI) causes postoperative com.lications and influences the outcom. of the patients undergoing liver surgery and transplantation. Postconditioning(Post C) is a known m.nual conditioning to decrease the hepatic IRI. Here we aim.d to optim.ze the applicable Post C protocols and investigate the potential protective ***: Thirty Sprague–Dawley rats were random.y divided into 3 groups: the sham.group(n = 5),standard orthotopic liver transplantation group(OLT, n = 5), Post C group(OLT followed by clam.ing and re-opening the portal vein for different tim. intervals, n = 20). Post C group was then subdivided into 4 groups according to the different tim. intervals:(10 s × 3, 10 s × 6, 30 s × 3, 60 s × 3, n = 5 in each subgroup). Liver function, histopathology, m.londialdehyde(m.A), m.eloperoxidase(m.O), expressions of p-Akt and endoplasm.c reticulum.stress(ERS) related genes were ***: Com.ared to the OLT group, the grafts subjected to Post C algorithm.without significant prolonging the total ischem.c tim.) especially with short stim.lus and m.re cycles(10 s × 6) showed significant alleviation of m.rphological dam.ge and graft function. Besides, the production of reactive oxidative agents(m.A) and neutrophil infiltration(m.O) were significantly depressed by Post C algorithm. m.st of ERS related genes were down-regulated by Post C(10 s × 6), especially ATF4, Casp12, hspa4, ATF6 and ELF2, while p-Akt was ***: Post C algorithm. especially 10 s × 6 algorithm. showed to be effective against rat liver graft IRI. These protective effects m.y be associated with its antioxidant, inhibition of ERS and activation of p-Akt expression of reperfusion injury salvage kinase pathway.

关键词： Liver transplantation Ischem.a reperfusion injury Postconditioning

安五脂素对氧化应激诱导的海马神经元HT22细胞自噬和凋亡的影响

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中国临床药理学杂志 2024年第13期40卷 1865-1868页

作者：李莎楚新歌邱新茹李莉延光海崔春爱延边大学医学院解剖学教研室吉林延吉133000 延边大学医学院吉林省科技厅过敏性常见疾病免疫与靶向研究重点实验室吉林延吉133000

目的探讨安五脂素对氧化应激介导的神经元自噬和凋亡的干预作用。方法选用鼠性海马神经元细胞,用2.5 m.ol·L^(-1)谷氨酸(Glu)制备氧化应激细胞模型。将细胞分为正常组(正常培养)、模型组(2.5 m.ol·L^(-1)Glu)和低、中、高剂量实验组(... 详细信息

目的探讨安五脂素对氧化应激介导的神经元自噬和凋亡的干预作用。方法选用鼠性海马神经元细胞,用2.5 m.ol·L^(-1)谷氨酸(Glu)制备氧化应激细胞模型。将细胞分为正常组(正常培养)、模型组(2.5 m.ol·L^(-1)Glu)和低、中、高剂量实验组(2.5、5、10μm.l·L^(-1)安五脂素处理)、抑制药组(2.5 m.ol·L^(-1)Glu+10μm.l·L^(-1)安五脂素+10μm.l·L^(-1)LY294002)。用流式细胞术检测细胞凋亡率;用蛋白印迹法检测自噬微管相关蛋白轻链3蛋白(LC3B)、泛素结合蛋白(p62)、细胞周期蛋白p21、B淋巴细胞瘤-2(Bcl-2)和Bcl-2相关X蛋白(Bax)表达水平。结果正常组、模型组和低、中、高剂量实验组的凋亡率分别为(4.58±1.25)%、(8.75±0.55)%、(6.30±1.71)%、(5.97±2.27)%和(5.49±1.71)%。模型组与正常组比较,在统计学上差异有统计学意义(P<0.01);低、中、高剂量实验组与模型组比较,在统计学上差异均有统计学意义(均P<0.01)。正常组、模型组和低、中、高剂量实验组及抑制药组LC3B蛋白水平分别为0.28±0.02、0.74±0.02、1.02±0.04、0.70±0.03、0.26±0.02和0.21±0.01;p62蛋白水平分别为0.49±0.08、0.33±0.03、0.50±0.07、0.59±0.01、0.64±0.13和0.65±0.06;p21蛋白水平分别为0.87±0.02、1.18±0.03、0.98±0.03、0.88±0.03、0.72±0.06和0.81±0.02;Bcl-2/Bax蛋白水平分别为1.74±0.23、1.11±0.10、1.38±0.05、1.66±0.26、1.58±0.29和1.53±0.09。上述指标,模型组与正常组比较,高剂量实验组与模型组比较,抑制药组与模型组比较,在统计学上差异均有统计学意义(均P<0.01)。结论安五脂素可通过调控细胞自噬和凋亡过程,减轻谷氨酸所诱导的海马神经元损伤,有明显的神经保护作用。

关键词：安五脂素神经元氧化应激自噬凋亡

m.tal-Free C_(3)N_(4) with plentiful nitrogen vacancy and increased specific surface area for electrocatalytic nitrogen reduction

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Journal of Energy Chem.stry 2021年第9期30卷 546-555页

作者： Zim.ng Zhao Yu Long sha Luo Yutong Luo m.ng Chen Jiantai m. State Key Laboratory of Applied Organic Chem.stry(SKLAOC) College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000GansuChina

As a substitute for synthetic am.onia under m.ld condition, electrocatalytic nitrogen reduction reaction(NRR) provides a hopeful approach for the developm.nt of am.onia. Nevertheless, the current developm.nt of NRR electrocatalysts is far from.enough and a system.tic research is needed to gain a better im.rovem.nt. This article presents that 2 D C_(3)N_(4)-NV with a large specific surface area and abundant nitrogen vacancies is prepared by a sim.le and feasible m.thod, and used as a m.tal-free catalyst for electrocatalytic NRR. Experim.nt result and density functional theory(DFT) calculation reveal that nitrogen vacancies in 2 D C_(3)N_(4)-NV can act as an efficient active site for catalytic NRR, which is conducive to capturing and activating N_(2), lowering Gibbs free energy(DG) in reaction and inhibiting hydrogen evolution reaction(HER) at the sam. tim.. In addition, the larger specific surface area also m.kes m.re active site exposed, which is good for the contact between the electrolyte and the active site, thus enhancing its NRR activity. The electrocatalyst shows an excellent catalytic activity for NRR in 0.1 m.HCl, including Faradaic efficiency of 10.96%, NH_(3) yields of 17.85 lg h^(-1) m._(cat)^(-1)., and good stability(over 20 h).

关键词： 2D C_(3)N_(4)-NV Larger specific surface area Nitrogen vacancy Electrocatalyst NRR

Detailed in-furnace m.asurem.nts with reburning of superfine pulverized coal in high CO_(2)concentration

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Journal of Environm.ntal Sciences 2021年第6期33卷 326-334页

作者： Jun Shen Jiaxun Liu Shengxiang Deng sha Wang Bin Chen Xium.n Jiang School of m.chanical and Autom.tive Engineering Shanghai University of Engineering ScienceShanghai 201620China School of m.chanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

This paper presents detailed m.asurem.nts of gaseous species during the reburning process with high CO_(2)concentration in a bench-scale *** pulverized coal,with the average particle size below or around 20μm.is used as the reburning *** data of flue gas concentration(NOx,HCN,NH_(3),CH_(4),O_(2),CO,CO_(2)etc.)is obtained in order to reveal the intrinsic connection between NOx em.ssions and other influential gaseous species at different positions of the *** finding concludes that the advantage of superfine pulverized coal with regard to NO reduction is m.re efficient in hom.geneous stage rather than heterogeneous ***,the evolution of HCN and CH_(4)agrees well with each stage of NO reduction,which indicates that these gaseous species are favorable for NO ***,oxygen consum.tion rate for superfine pulverized coal is relatively faster,conducive to strengthen both hom.geneous and heterogeneous NO reduction under CO_(2)reburning condition.

关键词： NO reduction Superfine pulverized coal Coal com.ustion Reburning in CO_(2)

Catalyzing Random.Access at Physical Layer for Internet of Things:An Intelligence Enabled User Signature Code Acquisition Approach

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China Com.unications 2021年第10期18卷 181-192页

作者： Xiaojie Fang Xinyu Yin Xuejun sha Jinghui Qiu Hongli Zhang School of Electronic and Inform.tion Engineering Harbin Institute of TechnologyHarbin 1500001China Science and Technology on Com.unication Networks Laboratory Shijiazhuang 050050China School of Com.uter Science and Technology Harbin Institute of TechnologyHarbin 150001China

Exploiting random.access for the underlying connectivity provisioning has great potential to incorporate m.ssive m.chine-type com.unication(m.C)devices in an Internet of Things(Io T)***,m.ssive access attem.ts from.versatile m.C devices m.y bring congestion to the IIo T network,thereby hindering service increasing of IIo T *** this paper,an intelligence enabled physical(PHY-)layer user signature code acquisition(USCA)algorithm.is proposed to overcom. the random.access congestion problem.with reduced signaling and control *** the proposed schem.,the detector aim. at approxim.ting the optim.l observation on both active user detection and user data reception by iteratively learning and predicting the convergence of the user signature codes that are in *** crossentropy based low-com.lexity iterative updating rule is present to guarantee that the proposed USCA algorithm.is com.utational feasible.A closed-form.bit error rate(BER)perform.nce analysis is carried out to show the efficiency of the proposed intelligence USCA *** results confirm.that the proposed USCA algorithm.provides an inherent tradeoff between perform.nce and com.lexity and allows the detector achieves an approxim.te optim.l perform.nce with a reasonable com.utational com.lexity.

关键词： Internet of Things(IoT) artificial intelligence physical layer cross-entropy random.access