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Anthropogenic pressures increase extinction risk of an isolated Asian elephant(Elephas m.xim.s)population in southwestern China,as revealed by a com.ination of m.lecular-and landscape-scale approaches

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Integrative Zoology 2022年第6期17卷 1078-1094页

作者： Ying CHEN Yakuan SUN Luciano atzeni Luke GIBSON m.i HUA Keyu LI Kun SHI David DUDGEON School of Ecology and Nature Conservation Beijing Forestry UniversityBeijingChina School of Biological Sciences The University of Hong KongHong KongChina Eco-Bridge Continental BeijingChina School of Environm.ntal Science and Engineering Southern University of Science and TechnologyShenzhenChina Institute of Special Anim.l and Plant Sciences of Chinese Academ. of Agricultural Sciences ChangchunChina School of Earth Sciences Yunnan UniversityKunmingChina

Identiﬁcation of the effect of anthropogenic threats on ecosystem.is crucial.We used m.lecular tools and rem.te sensing to evaluate the population status of an isolated Asian elephant population in southwestern China in response to changes in habitat suitability between 1989 and 2019.A total of 22 unique genotypes were identiﬁed from.117 dung sam.les collected between m.rch and June 2018 using m.crosatellite DNA analysis,including 13 m.les and 9 fem.les.Based on the size of fecal boli,1 anim.l was a juvenile,9 were subadults,and 12 were adults,indicating that recruitm.nt was lim.ted.The effective population size was sm.ll(15.3)but there was no signature of a recent population bottleneck.We observed a low genetic diversity(He=0.46±0.05)and a high level of inbreeding(Fis of 0.43±0.11),suggesting low population viability and high risk of extinction.In total,these elephants lost nearly two thirds(62%)of their habitat in 3 decades.The expansion of agriculture and rubber plantations followed by an increase in hum.n settlem.nts after 1989 increased the isolation of this population.We recom.end that resettlem.nt of 800 inhabitants of 2 villages and the abandonm.nt of associated farm.and and rubber plantations would m.ke an additional 20 km. of suitable habitat available.This could allow a population increase of 14 elephants,possibly by translocating individuals from.elsewhere in China.Ourﬁndings can be applied to the m.nagem.nt and conservation of other fragm.nted populations in China or in other range countries of Asian elephants.

关键词： fragm.ntation inbreeding isolation land-use change population viability

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Spatiotem.oral behavior of predators and prey in an arid environm.nt of Central Asia

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Current Zoology 2023年第6期69卷 670-681页

作者： m.rcello Franchini Luciano atzeni Sandro Lovari Battogtokh Nasanbat Sam.ya Ravchig Francisco Ceacero Herrador Giovanni Bom.ieri Claudio Augugliaro Departm.nt of Research and Conservation Wildlife Initiative ItaliaVia Rovigo1231040 Pederobba(TV)Italy Departm.nt of Agri-Food Environmental and Animal SciencesUniversity of UdineVia Sondrio 2/A33100UdineItaly Wildlife Institute School of Ecology and Nature ConservationBeijing Forestry UniversityBeijingChina m.rem.a Natural History m.seum Grossetoand Department of Life SciencesUniversity of SienaSienaItaly Faculty of Tropical AgriSciences Czech University of Life Sciences PraguePragueCzech Republic Institute of Biology Mongolian Academy of SciencesUlaanbaatarMongolia School of Arts and Sciences National University of MongoliaUlaanbaatarMongolia World Biodiversity Association—C/o m.seo Civico di Storia Naturale Lungadige Porta Vittoria 937129 VeronaItalia Wildlife Initiative Bayangol6th KhorooMicro District 10Ulaanbaatar 210349Mongolia Departm.nt of Ecology and Evolution University of LausanneBiophoreQuartier SorgeLausanneCH-1015Switzerland

The m.chanism. of interactions between apex and sm.ller carnivores m.y range from.com.etition to facilitation.Conversely,interactions between predators and prey are m.inly driven by the prey reducing the likelihood of encounters with predators.In this study,we investigated(1)the spatiotem.oral interactions between an apex(the snow leopard)and a m.so-predator(the red fox),and(2)the tem.oral interactions between the snow leopard and its potential prey(Siberian ibex,argali,Asian wild ass,Tolai hare)through cam.ra trapping in the m.ngolian Great Gobi-A.The probability of occurrence for the red fox was higher in the presence of the snow leopard than in its absence.m.reover,the red fox activity pattern m.tched that of the snow leopard,with both species m.stly active at sunset.This positive spatiotem.oral interaction suggests that the presence of the snow leopard m.y be beneficial for the red fox in term. of scavenging opportunities.However,other explanations m.y also be possible.Am.ngst prey,the Siberian ibex and the argali were m.inly active during the day,whereas the Asian wild ass and the Tolai hare were m.re nocturnal.These findings suggest that potential prey(especially the Siberian ibex and the argali)m.y shape their behavior to decrease the opportunity for encounters with the snow leopard.Our results have revealed com.lex interactions between apex and sm.ller predators andbetween apexpredatorand its potential prey.

关键词： avoidance facilitation m.ngolia Panthera uncia ungulates Vulpes vulpes

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Assessm.nt of habitat suitability of the snow leopard (Panthera uncia) in Qom.langm. National Nature Reserve based on m.xEnt m.deling

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Zoological Research 2018年第6期39卷 373-386页

作者： De-Feng Bai Peng-Ju Chen Luciano atzeni Lhaba Cering Qian Li Kun Shi Wildfife Institute School of Nature Conservation Beiiing Forestry University Beijing 100083 China Everest Snow Leopard Conservation Center Rikaze Xizang 857000 China Qom.langm. National Nature Reserve Adm.nistration Rikaze Xizang 857000 China Eco-Bridge Continental Beijing 100085 China

Habitat evaluation constitutes an im.ortant and fundam.ntal step in the m.nagem.nt of wildlife populations and conservation policy planning. Geographic inform.tion system.（GIS） and species presence data provide the m.ans by which such evaluation can be done. m.xim.m.Entropy （m.xEnt） is widely used in habitat suitability m.deling due to its power of accuracy and additional descriptive properties To survey snow leopard populations in Qom.langm. （m.. Everest） National Nature Reserve （QNNR）, Xizang （Tibet）, China, we pooled 127 pugm.rks, 415 scrape m.rks, and 127 non-invasive identifications of the anim.l along line transects and recorded 87 occurrences through cam.ra traps from.2014-2017. We adopted the m.xEnt m.del to generate a m.p highlighting the extent of suitable snow leopard habitat in QNNR. Results showed that the accuracy of the m.xEnt m.del was excellent （m.an AUC=0.921）. Precipitation in the driest quarter, ruggedness, elevation, m.xim.m.tem.erature of the warm.st m.nth, and annual m.an tem.erature were the m.in environm.ntal factors influencing habitat suitability for snow leopards, with contribution rates of 20.0%, 14.4%, 13.3%, 8.7%, and 8.2% respectively The suitable habitat area extended for 7 001.93 km.2, representing 22.72% of the whole reserve. The regions bordering Nepal were the m.in suitable snow leopard habitats and consisted of three separate habitat patches Our findings revealed that precipitation, tem.erature conditions, ruggedness, and elevations of around 4 000 m.a.s.I, influenced snow leopard preferences at the landscape level in QNNR. We advocate further research and cooperation with Nepal to evaluate habitat connectivity and to explore possible proxies of population isolation am.ng these patches. Furtherm.re, evaluation of subdivisions within the protection zones of QNNR is necessary to im.rove conservation strategies and enhance protection.

关键词： Qom.langm. National Nature Reserve Snow leopard m.xEnt Habitat suitability assessm.nt Tibet

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Com.ined therapeutic approach:Inflam.atory bowel diseases and peripheral or axial arthritis

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World Journal of Gastroenterology 2009年第20期15卷 2469-2471页

作者： Fabiola atzeni Sandro Ardizzone Luca Bertani m.rco Antivalle Alberto Batticciotto Piercarlo Sarzi-Puttini Rheum.tology Unit L. Sacco University Hospital Gastroenterology Unit L. Sacco UniversityHospital

Inflam.atory bowel diseases(IBDs), particularly Crohn's disease(CD) and ulcerative colitis(UC), are associated with a variety of extra-intestinal m.nifestations(EIm.).About 36% of IBD patients have at least one EIm. which m.st frequently affect the joints, skin, eyes and the biliary tract.The EIm. associated with IBD have a negative im.act on patients with UC and CD, and the resolution of m.st of them.parallels that of the active IBD in term. of tim.ng and required therapy;however, the clinical course of EIm. such as axial arthritis, pyoderm. gangrenosum. uveitis, and prim.ry sclerosing cholangitis is independent of IBD activity.The peripheral and axial arthritis associated with IBD have traditionally been treated with sim.le analgesics, non-steroidal anti-inflam.atory drugs, steroids, sulfasalazine, m.thotrexate, local steroid injections and physiotherapy, but the introduction of biological response m.difi ers such as tum.r necrosis factor-α blockers, has led to further im.rovem.nts.

关键词：溃疡性结肠炎综合治疗关节炎鸡传染性法氏囊病轴向炎症信息管理系统非甾体抗炎药

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An evaluation of sustainability and societal im.act of high-power laser and fusion technologies:a case for a new European research infrastructure

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High Power Laser Science and Engineering 2021年第4期9卷 66-69页

作者： S.atzeni D.Batani C.N.Danson L.A.Gizzi m.Perlado m.Tatarakis V.Tikhonchuk L.Volpe Dipartim.nto SBAI Universitàdi Roma"La Sapienza"Roma 00161Italy CELIA Universitéde Bordeaux-CNRS-CEAUMR 510733405 TalenceFrance AWE AldermastonReading RG74PRUK Centre for Intertial Fusion Studies Blackett LaboratoryImperial College LondonLondon SW72AZUK Istituto Nazionale di Ottica Consiglio Nazionale delle Ricerche56125 PisaItaly Instituto Fusión Nuclear"Guillerm. Velarde"Universidad Politecnica 28006 MadridSpain Institute of Plasm. Physics and Lasers Hellenic Mediterranean University Research Centre74100 RethymnoGreece Departm.nt of Electronic Engineering Hellenic Mediterranean University73133 ChcmiaGreece ELI-Beam.ines Center Institute of PhysicsCzech Academy of Sciences25241 Dolni BrezanyCzech Republic Centro de Laseres Pulsados(CLPU) Parque CientificoE-37185 VillamayorSalamancaSpain Laser-Plasm. Chair at the University of Salam.nca E-37185 VillamayorSalamancaSpain

Fusion energy research is delivering im.ressive new results em.rging from.different infrastructures and industrial devices evolving rapidly from.ideas to proof-of-principle dem.nstration and aim.ng at the conceptual design of reactors for the production of electricity.A m.jor m.lestone has recently been announced in laser fusion by the Lawrence Liverm.re National Laboratory and is giving new thrust to laser-fusion energy research worldwide.Here we discuss how these circum.tances strongly suggest the need for a European interm.diate-energy facility dedicated to the physics and technology of laser-fusion ignition,the physics of fusion m.terials and advanced technologies for high-repetitionrate,high-average-power broadband lasers.We believe that the participation of the broader scientific com.unity and the increased engagem.nt of industry,in partnership with research and academ.c institutions,m.ke m.st tim.ly the construction of this infrastructure of extrem. scientific attractiveness.

关键词： fusion energy high power lasers plasm.s inertial fusion high energy density

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Search for the doubly charm.d baryon ?cc~+

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Science China(Physics,m.chanics & Astronom.) 2021年第10期64卷 6-17页

作者： R. Aaij C. Abellán Beteta T. Ackernley B. Adeva m. Adinolfi H. Afsharnia C. A. Aidala S. Aiola Z. Ajaltouni S. Akar J. Albrecht F. Alessio m. Alexander A. Alfonso Albero Z. Aliouche G. Alkhazov P. Alvarez Cartelle S. Am.to Y. Am.is L. An L. Anderlini A. Andreianov m. Andreotti F. Archilli A. Artam.nov m. Artuso K. Arzym.tov E. Aslanides M. Atzeni B. Audurier S. Bachm.nn m. Bachm.yer J. J. Back P. Baladron Rodriguez V. Balagura W. Baldini J. Baptista Leite R. J. Barlow S. Barsuk W. Barter m. Bartolini F. Baryshnikov J. m. Basels G. Bassi B. Batsukh A. Battig A. Bay m. Becker F. Bedeschi I. Bediaga A. Beiter V. Belavin S. Belin V. Bellee K. Belous I. Belov I. Belyaev G. Bencivenni E. Ben-Haim.A. Berezhnoy R. Bernet D. Berninghoff H. C. Bernstein C. Bertella A. Bertolin C. Betancourt F. Betti I. Bezshyiko S. Bhasin J. Bhom.L. Bian m. S. Bieker S. Bifani P. Billoir m. Birch F. C. R. Bishop A. Bitadze A. Bizzeti m. Bj?rn m. P. Blago T. Blake F. Blanc S. Blusk D. Bobulska J. A. Boelhauve O. Boente Garcia T. Boettcher A. Boldyrev A. Bondar N. Bondar S. Borghi m. Borisyak m. Borsato J. T. Borsuk S. A. Bouchiba T. J. V. Bowcock A. Boyer C. Bozzi m. J. Bradley S. Braun A. Brea Rodriguez m. Brodski J. Brodzicka A. Brossa Gonzalo D. Brundu A. Buonaura C. Burr A. Bursche A. Butkevich J. S. Butter J. Buytaert W. Byczynski S. Cadeddu H. Cai R. Calabrese L. Calefice L. Calero Diaz S. Cali R. Calladine m. Calvi m. Calvo Gom.z P. Cam.rgo m.galhaes P. Cam.ana A. F. Cam.overde Quezada S. Capelli L. Capriotti A. Carbone G. Carboni R. Cardinale A. Cardini I. Carli P. Carniti L. Carus K. Carvalho Akiba A. Casais Vidal G. Casse m. Cattaneo G. Cavallero S. Celani J. Cerasoli A. J. Chadwick m. G. Chapm.n m. Charles P. Charpentier G. Chatzikonstantinidis C. A. Chavez Barajas m. Chefdeville C. Chen S. Chen A. Chernov V. Chobanova S. Cholak m. Chrzaszcz A. Chubykin V. Chulikov P. Ciam.rone m. F. Cicala X. Cid Vidal G. Ciezarek P. E. L. Clarke m. Clem.ncic H. V. Clif J. Closier J. L. Cobbledick V. Coco J. A. B. Coelho J. Cogan E. Cogneras L. AGH-University of Science and Technology Faculty of Computer Science Electronics and Telecommunications AGH-University of Science and Technology Faculty of Physics and Applied Computer Science Aix m.rseille Univ Budker Institute of Nuclear Physics (SB RAS) Cavendish Laboratory University of Cambridge Center for High Energy Physics Tsinghua University Centro Brasileiro de Pesquisas Físicas (CBPF) DS4DS La Salle Universitat Ramon Llull Departam.nto de Fisica Universidad Nacional de Colombia Departm.nt of Physics and Astronom. University of Manchester Departm.nt of Physics and Astronom. Uppsala University Departm.nt of Physics University of Oxford Departm.nt of Physics University of Warwick Eotvos Lorand University European Organization for Nuclear Research (CERN) Fakult?t Physik Technische Universit?t Dortmund Guangdong Provencial Key Laboratory of Nuclear Science Institute of Quantum Matter South China Normal University H.H. Wills Physics Laboratory University of Bristol Hangzhou Institute for Advanced Study UCAS Hanoi University of Science Henryk Niewodniczanski Institute of Nuclear Physics Polish Academ. of Sciences Horia Hulubei National Institute of Physics and Nuclear Engineering I. Physikalisches Institut RWTH Aachen University ICCUB Universitat de Barcelona INFN Laboratori Nazionali di Frascati INFN Sezione di Bari INFN Sezione di Bologna INFN Sezione di Cagliari INFN Sezione di Ferrara INFN Sezione di Firenze INFN Sezione di Genova INFN Sezione di m.lano INFN Sezione di m.lano-Bicocca INFN Sezione di Perugia INFN Sezione di Pisa INFN Sezione di Rom. La Sapienza INFN Sezione di Rom. Tor Vergata Im.erial College London Institut für Physik Universit?t Rostock Institute Of High Energy Physics (IHEP) Institute for High Energy Physics NRC Kurchatov Institute (IHEP NRC KI) Institute for Nuclear Research of the National Academ. of Sciences (KINR) Institute for Nuclear Research of the Russian Academ. of Sciences (INR RAS) Institute of Nuclear Physics Moscow State University (SINP MSU) Institut

A search for the doubly charm.d baryon ?cc~+ with the decay m.de ?cc~+→Ξc~+K~-π~+ is perform.d using proton-proton collision data at a centre-of-m.ss energy of 13 TeV collected by the LHCb experim.nt from.2016 to 2018, corresponding to an integrated lum.nosity of 5.4 fb-1. No significant signal is observed within the invariant m.ss range of 3.6 to 4.0 GeV/c~2. Upper lim.ts are set on the ratio R of the production cross-section tim.s the total branching fraction of the ?cc~+→Ξc~+K~-π~+ decay with respect to the Ξcc++→Λc~+K~-π~+π~+ decay. Upper lim.ts at 95% credibility level for R in the range 0.005 to 0.11 are obtained for diferent hypotheses on the ?cc~+ m.ss and lifetim. in the rapidity range from.2.0 to 4.5 and transverse m.m.ntum.range from.4 to 15 GeV/c.

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Fuel-ion diffusion in shock-driven inertial confinem.nt fusion im.losions

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m.tter and Radiation at Extrem.s 2019年第5期4卷 50-54页

作者： Hong Sio Chikang Li Cody E.Parker Brandon Lahm.nn Ari Le Stefano atzeni Richard D.Petrasso Plasm. Science and Fusion Center Massachusetts Institute of TechnologyCambridgeMassachusetts 02139USA Los Alam.s National Laboratory Los AlamosNew Mexico 87545USA Dipartim.nto SBAI Universita degli Studi di Roma“La Sapienza”Via Antonio Scarpa 1400161RomaItaly

The im.act of fuel-ion diffusion in inertial confinem.nt fusion im.losions is assessed using nuclear reaction yield ratios and reaction histories.In T3He-gas-filled(with trace D)shock-driven im.losions,the observed TT/T3He yield ratio is∼23lower than expected from.tem.erature scaling.InD3He-gas-filled(with trace T)shock-driven im.losions,the tim.ng of theD3He reaction history is∼50 ps earlier than those of the DT reaction histories,and average-ion hydrodynam.c sim.lations cannot reconcile this tim.ng difference.Both experim.ntal observations are consistent with reduced T ions in the burn region as predicted by m.lti-ion diffusion theory and particle-in-cell sim.lations.

关键词： diffusion shock filled

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High-speed integrated QKD system

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Photonics Research 2023年第6期11卷 1007-1014页

作者： REBECKA SAX ALBERTO BOARON GIANLUCA BOSO SIm.NE atzeni ANDREA CRESPI FADRI GRÜNENFELDER DAVIDE RUSCA AWS AL-SAADI DANILO BRONZI SEBASTIAN KUPIJAI HANJO RHEE ROBERTO OSELLAm. HUGO ZBINDEN Group of Applied Physics University of Geneva1205 GenèveSwitzerland ID Quantique SA 1227 GenèveSwitzerland Institute for Photonics and Nanotechnologies and NO-IFN CNR-IFN20133 MilanoItaly Dipartim.nto di Fisica Politecnico di Milano20133 MilanoItaly Sicoya Gm.H 12489 BerlinGermany

Quantum.key distribution(QKD)is nowadays a well-established m.thod for generating secret keys at a distance in an inform.tion-theoretically secure way,as the secrecy of QKD relies on the laws of quantum.physics and not on com.utational com.lexity.In order to industrialize QKD,low-cost,m.ss-m.nufactured,and practical QKD setups are required.Hence,photonic and electronic integration of the sender's and receiver's respective com.onents is currently in the spotlight.Here we present a high-speed(2.5 GHz)integrated QKD setup featuring a transm.tter chip in silicon photonics allowing for high-speed m.dulation and accurate state preparation,as well as a polarization-independent low-loss receiver chip in alum.num.borosilicate glass fabricated by the fem.osecond laser m.crom.chining technique.Our system.achieves raw bit error rates,quantum.bit error rates,and secret key rates equivalent to a m.ch m.re com.lex state-of-the-art setup based on discrete com.onents[A.Boaron et al.,Phys.Rev.Lett.121,190502(2018)].

关键词： technique QKD polarization

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Clinical features,course and outcom. in patients with late-onset SLE

Clinical features,course and outcome in patients with late-o...

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The 8th International Congress on SLE

作者： Fabiola atzeni Luca Iaccarino Piercarlo Sarzi-Puttini Anna Ghirardello Alberto Batticciotto Sandra Zam.ieri Rheum.tology Unit L Sacco University HospitalMilan-Italy Chair of Rheum.tology University of PaduaItaly Chair of Rheum.tology University of PaduaItaly Rheum.tology Unit L Sacco University HospitalMilan-Italy Chair of Rheum.tology University of PaduaItaly

＜正＞Purpose:System.c lupus erythem.tosus（SLE）is uncom.on after the age of 50 years.Age at onset has been recognized as having a m.difying effect on the clinical m.nifestations of SLE;thus,the elderly m.y constitute a specific SLE patient subgroup.Aim.of this study was to exam.ne the type and extent of clinical involvem.nt and outcom. in late-onset（LO-SLE）versus early-onset （EO-SLE）SLE.

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Observation and m.delling of stim.lated Ram.n scattering driven by an optically sm.othed laser beam.in experim.ntal conditions relevant for shock ignition

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High Power Laser Science and Engineering 2021年第4期9卷 160-178页

作者： G.Cristoforetti S.Hüller P.Koester L.Antonelli S.atzeni F.Baffigi D.Batani C.Baird N.Booth m.Galim.erti K.Glize A.Héron m.Khan P.Loiseau D.m.ncelli m.Notley P.Oliveira O.Renner m.Sm.d A.Schiavi G.Tran N.C.Woolsey L.A.Gizzi Intense Laser Irradiation Laboratory INO-CNRINO-CNR56124 PisaItaly Centre de Physique Théorique CPHT CNRSIP ParisEcole Polytechnique91128 PalaiseauFrance York Plasm. Institute Department of PhysicsUniversity of YorkYork YO105DDUK Dipartim.nto SBAI Universitàdi Roma'La Sapienza'00161 RomaItaly Universitéde Bordeaux CNRSCEACELIA33405 TalenceFrance STFC Rutherford Appleton Lab Central Laser FacilityDidcot SN21SZUK Key Laboratory for Laser Plasm.s(m.E) Shanghai Jiao Tong UniversityShanghai 200240China CEA DAMDIF91297 ArpajonFrance UniversitéParis-Saclay CEALMCE91680 Bruyeres-le-ChatelFrance Institute of Physics ELI BeamlinesInstitute of Plasma PhysicsCzech Academy of Sciences18221 PragueCzech Republic Helm.oltz-Zentrum.Dresden-Rossendorf 01328 DresdenGermany

We report results and m.delling of an experim.nt perform.d at the Target Area West Vulcan laser facility,aim.d at investigating laser±plasm. interaction in conditions that are of interest for the shock ignition schem. in inertial confinem.nt fusion(ICF),that is,laser intensity higher than 10^(16) W/cm.(2) im.inging on a hot(T>1 keV),inhom.geneous and long scalelength pre-form.d plasm..m.asurem.nts show a significant stim.lated Ram.n scattering(SRS)backscattering(;%-20%of laser energy)driven at low plasm. densities and no signatures of two-plasm.n decay(TPD)/SRS driven at the quarter critical density region.Results are satisfactorily reproduced by an analytical m.del accounting for the convective SRS growth in independent laser speckles,in conditions where the reflectivity is dom.nated by the contribution from.the m.st intense speckles,where SRS becom.s saturated.Analytical and kinetic sim.lations well reproduce the onset of SRS at low plasm. densities in a regim. strongly affected by non-linear Landau dam.ing and by filam.ntation of the m.st intense laser speckles.The absence of TPD/SRS at higher densities is explained by pum. depletion and plasm. sm.othing driven by filam.ntation.The prevalence of laser coupling in the low-density profile justifies the low tem.erature m.asured for hot electrons(7-12 keV),which is well reproduced by num.rical sim.lations.

关键词： plasm. sim.lations shock ignition stim.lated Ram.n scattering inertial confinem.nt fusion laser-plasm. interaction

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