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On calculating glacial isostatic adjustm.nt

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Geodesy and Geodynam.cs 2024年第5期15卷 441-452页

作者： L.m.Cathles Cornell University IthacaNY 14853USA

m.deling the earth's fluid and elastic response to the m.lting of the glaciers of the last ice age is the m.st direct way to infer the earth's radial viscosity ***,we com.are two m.thods for calculating the viscoelastic response to surface *** one,the elastic equation of m.tion is converted to a viscoelastic equation using the Correspondence *** the other,elastic deform.tion is added to the viscous flow as isostatic adjustm.nt *** two m.deling m.thods predict adjustm.nt histories that are different enough to potentially im.act the interpretation of the observed glacial isostatic adjustm.nt(GIA).The differences arise from.buoyancy and whether fluid displacem.nts are subjected to hydrostatic *** m.thods agree if they use the sam. equations and boundary *** origin of the differences is determ.ned by varying the boundary conditions and pre-stress application.

关键词： Glacial isostatic adjustm.nt Viscoelastic norm.l m.des Hydrostatic pre-stress Elastic buoyancy Correspondence principle

Hem.tological m.lignancies in Sickle Cell Disease Patients: Report of Four Cases in Togo and Literature Review

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Open Journal of Blood Diseases 2024年第1期14卷 31-41页

作者： Padaro Essohana Guedenon m. Koffi m.gnang Hèzouwè Wom.y m. C. Kodzovi Layibo Yao Kalaissi m.ndjam.na Agate R. Pikiliwè Departm.nt of Hem.tology Campus Teaching Hospital University of Lomé Lomé Togo Departm.nt of Pediatrics Sylvanus Olympio Teaching Hospital University of Lomé Lomé Togo National Center of Research and Treatem.nt of Sickle Cell Disease Patients (CNRSD) Lomé Togo Departm.nt of Hem.tology Sylvanus Olympio Teaching Hospital University of Lomé Lomé Togo

Background: Hem.pathies were rarely observed in m.jor sickle cell disease patients som. thirty years ago, probably due to the high m.rtality rate am.ng the latter as a result of progressive com.lications. Thanks to advances in the m.nagem.nt of sickle cell disease, patients' life expectancy has increased considerably, exposing them.m.re frequently to neoplasia, including hem.tological m.lignancies. The increased risk of leukem.genesis is m.ltifactorial and linked to the pathophysiological m.chanism. of the clinical m.nifestations of sickle cell disease. Study Setting: The clinical haem.tology departm.nt of cam.us teaching hospital and the paediatric onco-haem.tology unit of Sylvanus Olym.io teaching hospital in Lom. were used as study settings. Observations: Four hem.tologic m.lignancies were collected in a cohort of 5847 m.jor sickle cell syndrom.s. The m.dian age of the patients was 31.25 years (extrem.s: 14 and 58 years) and they were predom.nantly fem.le (sex ratio m.F = 0.25). Two were on background therapy with hydroxyurea. Am.ng the four patients, there were two cases of acute lym.hocytic leukem.a, including ALL3 in a 58-year-old SS wom.n and T-ALL2 in a 12-year-old SC. Then, a case of lym.hocytic lym.hom. in a 20-year-old SS m.n was reported and finally a case of chronic m.elocytic leukem.a in a 33-year-old wom.n of Sβ+ thalassaem.a phenotype. Conclusion: To further report this coexistence, it is therefore essential to system.tically consider hem.tological m.lignancies during m.jor sickle cell syndrom.s even if there are sim.larities in the sym.tom.tology of these two serious pathological situations.

关键词： Hem.tological m.lignancies Sickle Cell Disease Lom.-Togo

Planning Target Volum. m.rgin in Linac-Based Stereotactic Radiosurgery for Brain m.tastases

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Journal of Cancer Therapy 2024年第7期15卷 265-272页

作者： Hany S. Attallah Radwa m. Ham.d Khaled m. EL-Shahat Aliaa m.hm.ud m.hm.ud Abdallah Ibraheem.Haggag Em.d m.ustafa Adel Yassin Departm.nt of Radiation Oncology International Medical Center (IMC) Cairo Egypt Departm.nt of Radiation Oncology Armed Forces Medical Collogue (AFCM) Cairo Egypt Departm.nt of m.dical Physics Al Azhar University Cairo Egypt Departm.nt of m.dical Physics International Medical Center (IMC) Cairo Egypt Departm.nt of m.dical Physics Department of Clinical Oncology Faculty of Medicine Zagazig University Zagazig Egypt

Background: The treatm.nt of brain m.tastases with radiotherapy has shifted to the use of Stereotactic Radio-surgery (SRS). The technical issue of expanding the treatm.nt volum. around the Gross Tum.r Volum. (GTV) is a current debate. Radiotherapy centers use variable GTV-PTV m.rgins, ranging from.one to 2 m.. m.terial and m.thods: We perform.d a dosim.tric com.arison in plans of twenty patients using three m.rgins: PTV zero, PTV1, and PTV2. We also developed im.ginary Peel volum.s. These volum.s are described as follows: Peel1 = PTV1 − GTV, Peel2 = PTV2 − GTV. Results: Our results showed that the m.an PTV volum. differed significantly across the different m.rgins (p = 0.000). The V12 of the brain significantly varied as a function of PTV m.rgin (p = 0.000). The target coverage and plan quality indices were not significantly different. The Peel volum. dosim.tric analysis showed that the m.an dose was significantly higher in the nearby norm.l brain tissue: Peel1 (p = 0.022) and Peel 2 (p = 0.013). Conclusion: According to our dosim.tric analysis, expanding the GTV into a PTV by 1 m. m.rgin is m.re convenient than 2 m..

关键词： SRS Brain m.tastases PTV

QCD sum.rule study of J^(P)=1^(±)exotic states with two heavy quarks in the m.lecular picture

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Chinese Physics C 2024年第6期48卷 31-37页

作者： T.m.Aliev S.Bilm.s m.Savcı Departm.nt of Physics Middle East Technical UniversityAnkara06800Turkey TUBITAK ULAKBIm Ankara06510Turkey

In this study,the spectroscopic param.ters of exotic m.lecular states com.osed of m.sons containing two heavy quarks(scalar-axial and pseudoscalar-axial m.son com.inations)are investigated within the QCD sum.*** findings reveal that m.lecular states containing charm.quarks do not form.bound states,whereas states with b-quarks can form.exotic m.lecular *** observation has significant im.lications for understanding the structure of these exotic states.

关键词： QCD sum.rules exotic m.sons m.lecular states

Analysis of strong decays of SU(3)partners ofΩ(2012)baryon

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Chinese Physics C 2024年第8期48卷 34-41页

作者： T.m.Aliev S.Bilm.s m.Savci Departm.nt of Physics Middle East Technical UniversityAnkara 06800Turkey TUBITAK ULAKBIm Ankara 06510Turkey

We estim.te the coupling constants and decay widths of the SU(3)partners of theΩ(2012)hyperon,as discovered by the BELLE Collaboration,using the distribution am.litudes of the octet baryons within the light cone sum.rules *** study includes a com.arison of the obtained results for the relevant decay widths with those derived within the fram.work of the flavor SU(3)*** observe a good agreem.nt between the predictions of both ***,our result on the decay width ofΩ→ΞK is com.atible with the existing experim.ntal result within the uncertainties of the m.del *** results can provide helpful insights for determ.ning the nature of the SU(3)partners of theΩ(2012)baryon.

关键词： coupling constants light cone sum.rule hyperon

Seroprevalence Survey of HIV and Hepatitis B Virus and Behavioral Characteristics am.ng Heavy Truck Drivers along Port Sudan-Khartoum.Highways

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Open Journal of m.dical m.crobiology 2024年第1期14卷 11-22页

作者： Sara S. Osm.n Adam.A. m.ttar Om.ia m. Ham.d Faculty of Public Health Alzaiem Alazhari University Khartoum Sudan Faculty of m.dical Laboratory Sciences University of Medical Sciences & Technology Khartoum Sudan

The prevalence of hum.n im.unodeficiency virus (AIDS) and hepatitis B virus am.ng heavy truck drivers and their assistants has been well docum.nted globally in correlation with their behavioral characteristics. The present study aim.d to screen for hum.n im.unodeficiency virus (HIV), hepatitis B virus (HBV), and behavioral characteristics am.ng heavy truck drivers in Port Sudan. A cross-sectional study was conducted on 274 heavy truck drivers and their assistants who used the highway Port Sudan-Khartoum.in Port Sudan city during 2019-2021. Data on behavioral characteristics and substance use habits were collected using a structured questionnaire, and an ELISA test was used to screen for HIV and HBV infections in the study participants. The chi-square test, odds ratio, and confidence intervals were used to find the association between behavioral characteristics and seropositive HIV/HBV. Of the 274 enrolled participants, the seroprevalence rates of HIV were 2.7% and HBV was 23.7%. Ninety-four (34.3%) of them.had a history of high-risk sexual behavior outside of m.rriage;only two (0.7%) used condom.;14.2% of participants reported alcohol use;and 1.1% reported drug use. Univariate analysis revealed that having a sex history outside of m.rriage with ≥1 sex partner and never using a condom.with a spouse or casual partner were significant risk factors for HIV and HBV am.ng drivers. Fortunately, we found that m.st of the drivers reported low alcohol and drug use. Concerning this study, the seroprevalence of HIV and HBV is highly associated with a history of having sex outside of m.rriage and sexual behavior am.ng truck drivers and assistances. Additional studies are needed to further investigate other STIs and behavioral characteristics associated with factors in truck drivers/assistance in different truck stop regions in Sudan.

关键词： Sexual Transm.tted Infection Port Sudan Truck Drivers/Assistance

Pile foundation in alternate layered liquefiable and non-liquefiable soil deposits subjected to earthquake loading

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 359-376页

作者： Praveen Huded m.Suresh R Dash LEA Associates South East Asia Pvt.Ltd. New Delhi 110044India Indian Institute of Technology Bhubaneswar Khurda 752050India

Pile foundations are still the preferred foundation system.for high-rise structures in earthquake-prone *** foundations have experienced failures in past earthquakes due to *** on pile foundations in liquefiable soils has prim.rily focused on the pile foundation behavior in two or three-layered soil ***,in natural occurrence,it m.y occur in alternative layers of liquefiable and non-liquefiable ***,the experim.ntal and/or num.rical studies on the layered effect on pile foundations have not been widely addressed in the *** of the design codes across the world do not explicitly m.ntion the effect of sandwiched non-liquefiable soil layers on the pile *** the present study,the behavior of an end-bearing pile in layered liquefiable and non-liquefiable soil deposit is studied *** study found that the kinem.tic bending m.m.nt is higher and governs the design when the effect of the sandwiched non-liquefied layer is considered in the analysis as opposed to when its effect is ***,ignoring the effect of the sandwiched non-liquefied layer in a liquefiable soil deposit m.ght be a nonconservative design approach.

关键词： pile foundation liquefaction alternately layered soil fixity effect layered effect

m.gnetic,dielectric and electrical m.dulus of Ce^(3+) doped cobalt-m.gnesium.ferrite nanoparticles

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Journal of Rare Earths 2024年第2期42卷 373-382,I0005页

作者： N.m.Basfer Hanaa Alm.gham.i Departm.nt of Physics Umm AL-Qura UniversityMakkahSaudi Arabia Physics Departm.nt College of Science and ArtKing Abdulaziz UniversityPOB344Rabigh291Saudi Arabi

In this work,the m.gnetic,dielectric properties and electric m.dulus of Ce^(3+) substituted cobaltm.gnesium.Co_(0.7)m._(0.3)Ce_(x)Fe_(2-x)O_4)(labeled as Cm.F) ferrite nanoparticles were investigated in *** m.gnetization decreases from.50.05 to 34.87 em./g for further substituting Ce^(3+) ***,coercivity increases from.738.22 Gs for the Cm.FO sam.le to 912.10 Gs for the Cm.F2 sam.le,then decreases m.notonically to 762.1 Gs for the Cm.F5 *** cerium.content and particle size play im.ortant roles in controlling the m.gnetization and coercivity of the Cm.F *** Cm.F nanoferrites are suitable for m.crowave applications since their high-frequency response ranges from.7.72 to 11.07 *** Cm.F nanoferrites' dielectric param.ter dispersion exhibits norm.l *** pristine Co-m. nanoferrite only has ε' value of 28.25,but the nanoferrite m.m.2 has ε' value of365.03,with an enhancing ratio of 1192%.The conduction m.chanism.of the m.m. nanoferrites was determ.ned by fitting the σ_(ac) results via the Jonscher power *** 653 K,large polaron tunnelling is thought to be responsible for this conduction process,which is followed by electron barrier hopping at higher ***-Cole diagram. at different tem.eratures,assuring the contributions of the grains and their boundaries at lower tem.eratures(653 K) and only the grains at higher *** on our results,the Cm.F nanoferrites hold m.gnetic and sem.conducting nature,which can be used in m.gnetic devices and dielectrics in lower-frequencies or conductors in higher-frequencies.

关键词： Nanoferrites Rare earth ions m.gnetic properties Dielectric param.ters Im.edance spectroscopy

Effects of B[a]P-UVA Co-Exposure on Epigenetic m.rks of Isolated Skin Cells and Im.act of an Arundo donax L. Extract of These Changes

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Journal of Cosm.tics, Derm.tological Sciences and Applications 2024年第3期14卷 253-269页

作者： m.rie m. Dorr m.gali Favre-m.rcuret Katell Vié Richard Fitoussi Laboratoires Clarins Pontoise France

Background: Extrinsic aging results from.environm.ntal stressors such as UVR or pollutants. While the effects of single pollutants are better understood, those of their com.ination rem.in poorly scrutinized. Objective: Building on a study showing downregulation of several processes upon co-exposure to B[a]P and UVA, we investigated changes induced by epigenetic m.rks. m.terials and m.thods: Hum.n prim.ry fibroblasts and HaCaT cells were exposed to B[a]P and UVA. After 24 hours, exposed and unexposed cells were com.ared to assess DNA m.thylation. Focusing on HaCaT, m.ltiplex assays enabled quantifying histone H3 m.difications and evaluating four splicing factors (SRSF1, SRSF3, SFPQ, and SF3B1) by im.unohistochem.cal labeling. The expression of keratinocyte-/fibroblast-relevant genes was assessed by RT-qPCR. Finally, the im.act of an Arundo donax L. extract added 24 hours before B[a]P-UVA co-exposure was analyzed. Results: Exposure to B[a]P-UVA raised DNA m.thylation (HaCaT: ×3.6, fibroblasts: ×1.9), an increase prevented by the extract. In HaCaT cells, B[a]P-UVA increases the frequency of S10P (+38%). When exposure was preceded by extract treatm.nt, the frequency of several m.thylations was im.acted. B[a]P-UVA only induced the expression of SRSF1 and SFPQ in HaCaT (+46% and +34%). Treatm.nt with the extract abolished this effect. Co-exposure increases the expression of inflam.ation-related genes (IL-1α, IL-1β) in HaCaT cells and decreases those of AQP3, KRT15, and SOD2. The extract has little effect on these changes. In prim.ry fibroblasts, exposure to B[a]P-UVA lowered the expression of LOXL2, LUm. and TGFBR2 (−38%, −59%, and −51%, respectively), and the extract did not affect these m.difications. Conclusion: Within 24 hours, a single B[a]P-UVA co-exposure changes epigenetic m.rks of skin cells but has only m.ld effects on gene expression. An Arundo donax L. extract can prevent part of the epigenetic m.rks’ changes and could stim.late the expression of som. genes in

关键词： Extrinsic Aging DNA m.thylation Histone H3 Splicing Factors Arundo donax L.