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Effects of study area size on home range estimates of common bottlenose dolphins Tursiops truncatus

Current Zoology 2017年第6期63卷 693-701页

作者： Samantha R. NEKOLNY Matthew DENNY George BIEDENBACH Elisabeth M, HOWELLS Marilyn MAZZOIL Wendy N. DURDEN lydia moreland J. DAVID LAMBERT Quincy A, GIBSON University of North Florida Department of Biology 1 UNF Drive Jacksonville FL 32224 USA Georgia Aquarium Conservation Field Station 9509 Oceanshore Blvd Saint Augustine FL 32080 USA Harbor Branch Oceanographic Institute at Florida Atlantic University 5600US-1 North Fort Pierce FL 32958 USA Hubbs-SeaWorld Research Institute 3830 South Highway AIA #4-181 Melbourne Beach FL 32951 USA Harbor Branch Oceanographic Institute at Florida Atlantic University 5600 US-1 North Fort Pierce FL 32958 USA.

Knowledge of an animal's home range is a crucial component in making informed management decisions. However, many home range studies are limited by study area size, and therefore may underestimate the size of the home range. In many cases, individuals have been shown to travel outside of the study area and utilize a larger area than estimated by the study design. In this study, data collected by multiple research groups studying bottlenose dolphins on the east coast of Florida were combined to determine how home range estimates increased with increasing study area size. Home range analyses utilized photo-identification data collected from 6 study areas throughout the St Johns River (SJR; Jacksonville, FL, USA) and adjacent waterways, extending a total of 253 km to the southern end of Mosquito Lagoon in the Indian River Lagoon Estuarine System. Univariate kernel density estimates (KDEs) were computed for individuals with 10 or more sightings (20). Kernels were calculated for the primary study area (SJR) first, then additional kernels were calculated by combining the SJR and the next adjacent waterway; this continued in an additive fashion until all study areas were included. The 95% and 50% KDEs calculated for the SJR alone ranged from 21 to 35 km and 4 to 19 km, respectively. The 95% and 50% KDEs calculated for all combined study areas ranged from 116 to 217 km and 9 to 70 km, respectively. This study illustrates the degree to which home range may be underestimated by the use of limited study areas and demonstrates the benefits of conducting collaborative science.

关键词： bottlenose dolphin core area home range kernel analysis

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Neutrophils are shaped by the tumor microenvironment:novel possibilities for targeting neutrophils in cancer

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1788-1790页

作者： Carlos Silvestre-Roig lydia Kalafati Triantafyllos Chavakis Institute of Experimental Pathology(ExPat) Center for Molecular Biology of Inflammation(ZMBE)University of MünsterMünsterGermany Institute for Clinical Chemistry and Laboratory Medicine University Hospital and Faculty of MedicineTechnische Universität DresdenDresdenGermany

In a recent paper published in Science,Ng et *** seminal insights into the process through which neutrophils are reprogrammed by the tumor environment,leading to a convergent transition from different neutrophil states towards a unique end-stage differentiated pro-tumor phenotype.1 These findings have major translational implications as they provide potential neutrophil-related targets for tumor immunotherapy.

关键词： al. neutrophils tumor

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Glucagon-like peptide 1 agonists are potentially useful drugs for treating metabolic dysfunction-associated steatotic liver disease

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World Journal of Gastroenterology 2024年第30期30卷 3541-3547页

作者： Maurizio Soresi lydia Giannitrapani Department of Health Promotion Sciences Maternal and Infant CareInternal Medicine and Medical Specialties(PROMISE)University of PalermoPalermo 90127Italy

In this editorial,we comment on Yin et al’s recently published Letter to the *** particular,we focus on the potential use of glucagon-like peptide 1 receptor agonists(GLP-1RAs)alone,but even more so in combination therapy,as one of the most promising therapies in metabolic dysfunction-associated steatotic liver disease(MASLD),the new definition of an old condition,non-alcoholic fatty liver disease,which aims to better define the spectrum of steatotic *** is well known that GLP-1RAs,having shown outstanding performance in fat loss,weight loss,and improvement of insulin resistance,could play a role in protecting the liver from progressive *** clinical trials have shown that,among GLP-1RAs,semaglutide is a safe,well-studied therapeutic choice for MASLD patients;however,most studies demonstrate that,while semaglutide can reduce steatosis,including steatohepatitis histological signs(in terms of inflammatory cell infiltration and hepatocyte ballooning),it does not improve *** of therapies with different but complementary mechanisms of action are considered the best way to improve efficiency and slow disease progression due to the complex pathophysiology of the *** particular,GLP-1RAs associated with antifibrotic drug therapy,dual glucose-dependent insulinotropic polypeptide(GIP)/GLP-1RA or GLP-1 and glucagon RAs have promoted greater improvement in hepatic steatosis,liver biochemistry,and non-invasive fibrosis tests than ***,although to date there are no definitive indications from international drug agencies,there is the hope that soon the therapeutic lines in the most advanced phase of study will be able to provide a therapy for MASLD,one that will certainly include the use of GLP-1RAs as combination therapy.

关键词： Non-alcoholic fatty liver disease Glucagon-like peptide 1 Semaglutide Liver fibrosis Therapy

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Facile in situ synthesis and characterization of Fe@Si/zeolite Na composites with magnetic core–shell structures from natural materials for enhanced curcumin loading capacity

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Nanotechnology and Precision Engineering 2024年第2期7卷 69-86页

作者： Munasir Nasir Nuhaa Faaizatunnisa Muhammad Naufal Ariesta lydia Rohmawati Rifqi Aulia Nurazizah Department of Physics Faculty of Mathematics and Natural ScienceUniversitas Negeri Surabaya(Unesa)Surabaya60231Indonesia Department of Chemistry Faculty of Science and Data AnalyticsInstitut Teknologi Sepuluh Nopember(ITS)Surabaya 60111Indonesia Department of Chemistry Faculty of Mathematics and Natural SciencesUniversitas Sebelas Maret(UNS)Surakarta57126Indonesia Department of Medicine Faculty of Medical and Health ScienceUniversitas Islam Negeri(UIN)Maulana Malik IbrahimMalang65151Indonesia

Curcumin is a natural polyphenol that is used in various traditional ***,its inherent properties,such as its rapid degradation and metabolism,low bioavailability,and short half-life,are serious problems that must be *** this end,a drug carrier incorporating natural magnetic cores in a zeolite framework was developed and applied to the loading of curcumin in ethanol *** this system,curcumin is encapsulated in a zeolite Na(ZNA)magnetic core–shell structure(Fe@Si/ZNA),which can be easily synthesized using an in situ *** of Fe_(3)O_(4) nanoparticles was carried out from natural materials using a co-precipitation *** of the prepared magnetic core–shell structures and composites was carried out using vibrating-sample magnetometery,Fourier transform infrared spectroscopy,transmission electron microscopy,and x-ray *** cumulative loading of curcumin in the ZNA composite with 9%nanoparticles was found to reach 90.70%with a relatively long half-life of 32.49 *** tests of curcumin loading in the composite showed that adding magnetic particles to the zeolite framework also increased the stability of the composite *** kinetics and isotherm studies also found that the system follows the pseudo-second-order and Langmuir isotherm models.

关键词： Zeolite Na Magnetic core–shell nanoparticles(MNPs) ZNA Adsorption Curcumin

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Sex differences in Alzheimer's disease:an urgent research venue to follow

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Neural Regeneration Research 2024年第12期19卷 2569-2570页

作者： Raquel Jiménez-Herrera Ana Contreras Juan D.Navarro-López lydia Jiménez-Díaz Neurophysiology&Behavior Lab University of Castilla-La ManchaSchool of Medicine of Ciudad RealCiudad RealSpain

Due to increasing life expectancy,the amount of people with dementia worldwide is expected to experience a substantial rise,with estimates indicating a growth from 55 million in 2019 to a staggering 139 million by the... 详细信息

关键词： Alzheimer predominant estimates

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Global Optimization for Heilbronn Problem of Convex Polygons Based on Bilinear Matrix Inequalities Solving

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Journal of Systems Science & Complexity 2024年

作者： QI Niuniu DEHBI lydia LIU Banglong YANG Zhengfeng ZENG Zhenbing Shanghai Key Laboratory of Trustworthy Computing East China Normal University Department of Mathematics Shanghai University

This paper primarily focuses on solving the Heilbronn problem of convex polygons,which involves minimizing the area of a convex polygon P1P2···P_n while satisfying the condition that the areas of all triangles formed by consecutive vertices are equal to 1/*** problem is reformulated as a polynomial optimization problem with a bilinear objective function and bilinear constraints.A new method is presented to verify the upper and lower bounds for the optimization *** upper bound is obtained by the affine regular *** Bilinear Matrix Inequalities （BMI） theory and the branch-and-bound technique are used to verify the lower bound of the *** paper concludes by proving that the lower bound for the area minimization problem of a convex polygon with10 vertices is *** relative error compared to the global optimum is 0.104%.

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Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： Danko Jeremic lydia Jiménez-Díaz Juan D.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(AD)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in AD,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

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基于符号数值计算的代数曲线区间插值

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中国科学：数学 2024年第5期54卷 699-730页

作者： lydia Dehbi 杨争峰彭超徐姚晨曾振柄华东师范大学软件工程学院上海200062 上海大学数学系上海200444

本文研究的代数曲线区间插值问题,是针对预先给定平面上的若干矩形小邻域,构造经过它们的次数最低的代数曲线、项数最少的代数曲线以及系数是整数的代数曲线.本文将上述问题转化为优化问题,给出基于符号数值计算和Lagrange乘子法的求解... 详细信息

本文研究的代数曲线区间插值问题,是针对预先给定平面上的若干矩形小邻域,构造经过它们的次数最低的代数曲线、项数最少的代数曲线以及系数是整数的代数曲线.本文将上述问题转化为优化问题,给出基于符号数值计算和Lagrange乘子法的求解方法,应用这一方法解决了几个具体的有趣问题,包括基于太阳系行星、小行星和矮行星的轨道数据重新发现Kepler第三定律.

关键词：代数曲线数学机械化符号数值计算稀疏插值

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未完成:为什么我们会被不完美所吸引?

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艺术品鉴 2024年第2期 50-55页

作者： lydia Figes 不详

一件艺术品什么时候才算是真正完成?尽管艺术家在画布上花了很多时间来完善一幅画,但我们有时会更喜欢不完整的版本,为什么呢?无论是被刻意遗弃,还是因病、意外事变、甚至死亡而被遗弃,我们仍然可以通过观看艺术家的未完成作品来了解他... 详细信息

一件艺术品什么时候才算是真正完成?尽管艺术家在画布上花了很多时间来完善一幅画,但我们有时会更喜欢不完整的版本,为什么呢?无论是被刻意遗弃,还是因病、意外事变、甚至死亡而被遗弃,我们仍然可以通过观看艺术家的未完成作品来了解他们的创作过程。例如达·芬奇,众所周知,他的许多画没有完成,因为他是一个出了名的拖延者,或者至少,他总是从一个项目跳到另一个项目,即使前一幅未画完成。

关键词：达·芬奇一幅画艺术品被遗弃艺术家意外

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表达感激

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空中英语教室（高级版．彭蒙惠英语） 2024年第6期 6-6,38页

作者： lydia Dishman 不详

我们知道,人们喜欢因工作出色而得到认可。大多数时候,一句简单的“谢谢你”就足够了。事实上,我们人类依赖于这个举动。研究表明,养成感恩的习惯对我们的神经系统有立竿见影的效果,它能降低应激激素皮质醇,促进有益激素——血清素和多... 详细信息

我们知道,人们喜欢因工作出色而得到认可。大多数时候,一句简单的“谢谢你”就足够了。事实上,我们人类依赖于这个举动。研究表明,养成感恩的习惯对我们的神经系统有立竿见影的效果,它能降低应激激素皮质醇,促进有益激素——血清素和多巴胺——的分泌。

关键词：应激激素血清素皮质醇多巴胺神经系统立竿见影

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