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Long-Term Patterns of Meningitis Mortality:A Continual Downward Trend and a Vulnerable Infant Population—China,1987–2021

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China CDC weekly 2023年第34期5卷 745-750页

作者： Yu Wu Huiyun Fan Binbin Su Chao Guo luzhao feng Department of Population Health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina APEC Health Science Academy(HeSAY) Peking UniversityBeijingChina Institute of Population Research Peking UniversityBeijingChina Department of Infectious Diseases School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina.

Summary What is already known about this topic?Meningitis,a life-threatening disease,presents a significant public health *** rate of progress in burden reduction notably lags behind other diseases that can be prevented through *** is added by this report?This research explored the changes in the mortality rate of meningitis in China over a span of 35 *** study further identified the effects of age,period,and cohort on the mortality trends.

关键词： mortality diseases vaccination

City-Specific Effects of Lifting Mobility Restrictions—China, February–March 2020

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China CDC weekly 2022年第31期4卷 673-679页

作者： Shasha Han Libing Ma Ting Zhang luzhao feng Weizhong Yang Xiaoying Zheng Beijing International Center for Mathematical Research Peking UniversityBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Department of Respiratory and Critical Care Medicine the Affiliated Hospital of Guilin Medical UniversityGuilin CityGuangxi Zhuang Autonomous RegionChina

Summary What is already known about this topic?Government used mobility restrictions to help contain the first wave of coronavirus disease 2019(COVID-19)across cities in *** restrictions were lifted during times of non-zero incidence in response to a return to work order that went into effect on February 10,*** is added by this report?The effect of lifting mobility restrictions on COVID-19 death rate and incidence varied by city,with smaller increases or even reductions in cities with low community connectivity and small floating volume,and larger increases in cities with high community connectivity and large floating *** on recovery rates were similar across *** are the implications for public health practice?City-specific mobility restriction lifting is likely to be *** indexes,community connectivity and floating volume,can inform the design of city-specific mobility restriction lifting policies.

关键词： lifting floating China.

Attitudes Regarding Influenza Vaccination Among Public Health Workers during COVID-19 Pandemic — China, September 2022

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China CDC weekly 2023年第6期5卷 137-142页

作者： Heya Yi Yanlin Cao Jiemi Zhao Binshan Jiang Congxuan Bing Zijian feng Weizhong Yang Jiandong Zheng luzhao feng Chinese Preventive Medicine Association BeijingChina Chinese Academy of Medical Sciences Peking Union Medical CollegeBeijingChina Division of Infectious Disease Chinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?Public health workers(PHWs)were listed as a priority group recommended for influenza vaccination during the coronavirus disease 2019(COVID-19)*** the drivers of influenza... 详细信息

关键词： vaccine vaccination listed

Quantitative Analysis of the Effectiveness of Antigen-and Polymerase Chain Reaction-Based Combination Strategies for Containing COVID-19 Transmission in a Simulated Community

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Engineering 2023年第9期28卷 234-242页

作者： Qiangru Huang Yanxia Sun Mengmeng Jia Ting Zhang Fangyuan Chen Mingyue Jiang Qing Wang luzhao feng Weizhong Yang School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China School of Arts and Sciences Beijing Institute of Fashion TechnologyBeijing 100105China

The number of coronavirus disease 2019(COVID-19)cases continues to surge,overwhelming healthcare systems and causing excess mortality in many *** of infectious populations remains a key strategy to contain the COVID-19 outbreak,delay the exponential spread of the disease,and flatten the epidemic *** the Omicron variant outbreak as a background,this study aimed to evaluate the effectiveness of testing strategies with different test combinations and frequencies,analyze the factors associated with testing effectiveness,and optimize testing strategies based on these influencing *** developed a stochastic,agent-based,discrete-time susceptible–latent–infectious–recovered model simulating a community to estimate the association between three levels of testing strategies and COVID-19 *** testing and its combination strategies were more efficient than polymerase chain reaction(PCR)-related *** testing also showed better performance in reducing the demand for hospital beds and intensive care unit *** delay in the turnaround time of test results had a more significant impact on the efficiency of the testing strategy compared to the detection limit of viral load and detection-related *** main advantage of antigen testing strategies is the short turnaround time,which is also a critical factor to be optimized to improve PCR *** modifying the turnaround time,the strategies with less frequent testing were comparable to daily *** choice of testing strategy requires consideration of containment goals,test efficacy,community prevalence,and economic *** study provides evidence for the selection and optimization of testing strategies in the post-pandemic era and provides guidance for optimizing healthcare resources.

关键词： COVID-19 Antigen testing PCR testing Testing strategies

Increased Incidence of Scarlet Fever--China,1999−2018

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China CDC weekly 2019年第5期1卷 63-66页

作者： Yuanhai You Ying Qin Mark J.Walker luzhao feng Jianzhong Zhang State Key Laboratory for Infectious Disease Prevention and Control Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina Division of Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre The University of QueenslandBrisbaneQLDAustralia.

What is already known about this topic?Scarlet fever had high incidence between the 1950s and 1980s,but during the 1980s and 1990s,the incidence of scarlet fever dropped to a relatively low and stable levels in *** is added by this report?Starting in 2011,scarlet fever incidence significantly increased in *** the eight years between 2011 and 2018,479,555 cases were reported,which exceeded the total number of 241,365 cases reported in the previous twelve years 1999–*** are the implications for public health practice?Both patient and pathogen epidemiological surveillance need to be heightened to monitor serious cases of scarlet fever and to implement timely control measures.

关键词： fever Fever Incidence

An effectiveness study of vaccination and quarantine combination strategies for containing mpox transmission on simulated college campuses

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Infectious Disease Modelling 2024年第3期9卷 805-815页

作者： Qiangru Huang Yanxia Sun Mengmeng Jia Mingyue Jiang Yunshao Xu luzhao feng Weizhong Yang School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100730China National Institute of Pathogen Biology Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100730China

The ongoing transmission of mpox in specific countries and regions necessitates urgent *** is essential to implement targeted containment strategies that concentrate on high-risk populations and critical locations,such as college campuses,to effectively curb the spread of *** study is dedicated to evaluating the performance of various vaccination and quarantine strategies in curbing the spread of mpox and estimating the outbreak *** accomplish this,we constructed a stochastic,agent-based,discrete-time susceptible-latent-infectious-recovered(SLIR)model,to examine mpox transmission on a simulated college *** findings reveal that relying solely on PEP is insufficient in containing mpox *** bolster the population immunity and protect the vulnerable,pre-exposure vaccination among high-risk populations prior to an outbreak is *** study demonstrates that a pre-exposure vaccination rate of 50%in high-risk populations can led to a remarkable 74.2%reduction of *** translated to a mere 1.0%cumulative infection incidence in the overall *** cases where the desired vaccination coverage is not attainable,enhancing case detection and isolation measures can serve as an effective emergency response to contain mpox *** pre-exposure vaccination coverage of 20%or lower,a 40%isolation ratio is necessary to keep the cumulative number of infections in ***,when the coverage exceeds 30%,a reduced isolation ratio of 20%becomes sufficient to manage the outbreak *** insights underscore the importance of strategic pre-exposure vaccination in conjunction with robust surveillance and isolation protocols to safeguard public health and prevent the escalation of mpox outbreaks.

关键词： Infectious diseases Mpox Vaccination Quarantine

Experts’Consensus on the Management of Respiratory Disease Syndemic

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China CDC weekly 2024年第8期6卷 131-138页

作者： Weizhong Yang Zhongjie Li Ting Yang Yanming Li Zhengde Xie luzhao feng Zhibin Peng Jue Liu School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina State Key Laboratory of Respiratory Health and Multimorbidity BeijingChina Key Laboratory of Pathogen Infection Prevention and Control Peking Union Medical CollegeMinistry of EducationBeijingChina National Center for Respiratory Diseases State Key Laboratory of Respiratory Health and MultimorbidityNational Clinical Research Center for Respiratory DiseasesInstitute of Respiratory MedicineChinese Academy of Medical SciencesDepartment of Pulmonary and Critical Care MedicineCenter of Respiratory MedicineChina-Japan Friendship HospitalBeijingChina Department of Pulmonary and Critical Care Medicine National Center of GerontologyBeijing HospitalInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijingChina Beijing Key Laboratory of Pediatric Respiratory Infection Diseases Key Laboratory of Major Diseases in ChildrenMinistry of EducationNational Clinical Research Center for Respiratory DiseasesResearch Unit of Critical Infection in ChildrenChinese Academy of Medical Sciences2019RU016National Key Discipline of Pediatrics(Capital Medical University)Beijing Pediatric Research InstituteBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijingChina Chinese Center for Disease Control and Prevention BeijingChina Department of Epidemiology and Biostatistics School of PublicHealthKey Laboratory of Epidemiology of Major DiseasesMinistry of EducationPeking University Health Science Center-Weifang Joint Research Center for Maternal and Child HealthPeking UniversityBeijingChina

The global burden of respiratory diseases is a significant and increasing threat to individuals *** 2017,there were 544.9 million cases of chronic respiratory diseases,a 39.8%increase since 1990(1).These diseases were the third leading cause of global mortality in 2017,accounting for 7.0%of all deaths,an 18.0%increase compared to 1990.

关键词： diseases respiratory mortality

The Incoming Influenza Season—China,the United Kingdom,and the United States,2021–2022

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China CDC weekly 2021年第49期3卷 1039-1045页

作者： Shasha Han Ting Zhang Yan Lyu Shengjie Lai Peixi Dai Jiandong Zheng Weizhong Yang Xiaohua Zhou luzhao feng Beijing International Center for Mathematical Research Peking UniversityBeijingChina Harvard Medical School Harvard UniversityBostonMAUSA School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Academy for Advanced Interdisciplinary Studies Peking UniversityBeijingChina WorldPop School of Geography and Environmental ScienceUniversity of SouthamptonSouthamptonUK Division for Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina Department of Biostatistics School of Public HealthPeking UniversityBeijingChina National Engineering Laboratory of Big Data Analysis and Applied Technology Peking UniversityBeijingChina.

Introduction:Seasonal influenza activity has declined globally since the widespread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** has been scarce information to understand the future dynamics of influenza—and under different hypothesis on relaxation of nonpharmaceutical interventions(NPIs)in particular—after the disruptions to seasonal ***:We collected data from public sources in China,the United Kingdom,and the United States,and forecasted the influenza dynamics in the incoming 2021–2022 season under different *** considered Northern China and Southern China separately,due to the sharp difference in the patterns of seasonal *** the United Kingdom,data were collected for England ***:Compared to the epidemics in 2017–2019,longer and blunter influenza outbreaks could occur should NPIs be fully lifted,with percent positivity varying from 10.5 to 18.6 in the studying *** rebounds would be smaller if the maskwearing intervention continued or the international mobility stayed low,but sharper if the mask-wearing intervention was lifted in the middle of influenza ***,influenza activity could stay low under a much less stringent mask-wearing intervention coordinated with influenza ***:The results added to our understandings of future influenza dynamics after the global decline during the coronavirus disease 2019(COVID-19)*** light of the uncertainty on the incoming circulation strains and the relatively low negative impacts of mask wearing on society,our findings suggested that wearing mask could be considered as an accompanying mitigation measure in influenza prevention and control,especially for seasons after long periods of low-exposure to influenza *** influenza activity declines globally during the coronavirus disease 2019(COVID-19)pandemic(1–4).For instance,in China,influenza activity,as measured by percentage of submitted specimens testing

关键词： prevention globally continued

A Large-Scale Online Survey on Clinical Severity and Associated Risk Factors for SARS-CoV-2 Omicron Infection — China, April–May 2023

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China CDC weekly 2024年第15期6卷 305-311,I0001-I0004页

作者： Yanxia Sun Yuping Duan Jie Qian Yimin Qu Ye Wang Guohui Fan Qiangru Huang Zhongjie Li Weizhong Yang luzhao feng State Key Laboratory of Respiratory Health and Multimorbidity Key Laboratory of Pathogen Infection Prevention and ControlMinistry of EducationSchool of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina

What is already known about this topic?Individuals who initially contract severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)lack significant mixed ***,it is crucial to monitor the clinical characteristics and associated factors of these individuals in order to inform *** is added by this report?The common symptoms reported were fever,cough,and sore *** and receiving four vaccination doses within a 6-month period were found to be associated with a shorter duration of virus shedding,decreased hospitalization rate,and reduced risk of *** aged 60 years and older,as well as those with underlying medical conditions,had a higher risk of developing *** are the implication for public health practices?Online surveys conducted through social media platforms have the potential to complement disease surveillance and data collection *** terms of vaccination prioritization,it is recommended to prioritize older individuals and those with underlying diseases.

关键词： doses Online initially