检索结果-南通市图书馆

Effects of Tai Chi and Qigong on health indicators in people with lumbar disc herniation: A systematic review and meta-analysis

引用

Journal of Traditional Chinese Medical Sciences 2024年第4期11卷 395-404页

作者： Zhao, Anni Mao, Junru Cai, Yiqing Wang, Mi'na Rong, Hongguo Huang, Jingjing luo, xuanzhi Liu, Xin School of Life Sciences Beijing University of Chinese Medicine Centre for Evidence-Based Chinese Medicine Beijing University of Chinese Medicine Graduate School Beijing University of Chinese Medicine Department of Acupuncture and Moxibustion Beijing Hospital of Traditional Chinese Medicine Capital Medical University School of Human Movement and Nutrition Sciences The University of Queensland

Objective: To evaluate the effect of Tai Chi and Qigong on patients with lumbar disc herniation (LDH). Methods: Relevant data were retrieved from nine English and Chinese databases, including Cochrane Library, PubMed, and Wanfang Data, from inception to June 2024. All published randomized controlled trials assessing the effect of Tai Chi and Qigong on visual analog scale (VAS) pain, Japanese Orthopedic Association (JOA) score, and other health indicators in participants with LDH compared to usual medical care or other treatments were included. Grey literature, trials involving the pushing of hands (Tui Shou) or Tai Chi with weapons, and trials with co-interventions (Tai Chi/Qigong plus another treatment) were excluded. Methodological quality was analyzed using the Cochrane risk of bias tool, and evidence quality was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) tool. Meta-analyses were conducted using Stata 16.0 software. Results: Fourteen trials (954 patients) were included in this study. Tai Chi and Qigong were associated with lower VAS pain scores (standardized mean difference −0.55, 95% confidence interval [CI] −0.95 to −0.15, P =.01), higher JOA scores (mean difference [MD] 4.40, 95% CI 2.62 to 6.18, P <.001) and straight leg raise test scores (MD 9.40°, 95% CI 7.64 to 11.15, P <.001) in patients with LDH. Furthermore, compared with usual care, Tai Chi and Qigong showed enhanced effects on pain and JOA scores. When compared to other exercises or massage, the effect on pain scores was similar but that on JOA scores was significant. Conclusions: Tai Chi and Qigong may have favorable effects on VAS pain and JOA scores compared with usual care, and on JOA scores compared with other exercises or massage in patients with LDH. Given the overall poor quality of the evidence, the results of current study should be interpreted cautiously. © 2024 Beijing University of Chinese Medicine

关键词： Lumbar disc herniation Meta-analysis Qigong Randomized controlled trial Systematic review Tai Chi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于静息态功能磁共振探讨针刺治疗乳腺癌化疗相关认知障碍的脑机制

引用

中医杂志 2024年第5期65卷 495-502页

作者：吴子婷刘妮张亚男梁婷婷罗煊之张青北京中医药大学北京市100029 首都医科大学附属北京中医医院北京市朝阳区安贞社区卫生服务中心

目的基于静息态功能磁共振成像(rs-fMRI)探讨针刺治疗乳腺癌化疗相关认知障碍(CRCI)的作用机制。方法选取25名乳腺癌CRCI患者,以调和气血、补心益智治法进行针刺治疗,选穴为足三里(双侧)、血海(双侧)、膻中、中脘、气海、百会、风府(双... 详细信息

目的基于静息态功能磁共振成像(rs-fMRI)探讨针刺治疗乳腺癌化疗相关认知障碍(CRCI)的作用机制。方法选取25名乳腺癌CRCI患者,以调和气血、补心益智治法进行针刺治疗,选穴为足三里(双侧)、血海(双侧)、膻中、中脘、气海、百会、风府(双侧)、心俞(双侧)、通里(双侧)、照海(双侧)、(双侧),每周针刺2次,每次间隔2~3天,疗程8周。比较针刺前后蒙特利尔评分量表(MoCA)、简易智力量表(MMSE)、欧洲癌症研究与治疗组织生命质量问卷(EORTC QLQ-C30)量表评分,并进行MoCA量表疗效评价;治疗前后接受rs-fMRI检查,采用低频振荡振幅、功能连接(FC)分析方法,提取双侧前扣带回、双侧海马、双侧杏仁核、双侧颞极颞中回、双侧颞极颞上回等感兴趣区的zALFF平均值进行比较,并以治疗前后zALFF值差异具有统计学意义的脑区为种子点进行基于种子点的FC分析。对影像学指标与临床量表进行相关性分析。结果24名乳腺癌CRCI患者完成治疗及随访。治疗后患者rs-fMRI检查左侧海马、左侧杏仁核、左侧颞极颞中回的zALFF值降低(P<0.05或P<0.01),左侧颞极颞中回与右侧小脑后叶FC在针刺治疗后升高(t=-5.169),MoCA量表总分及视空间与执行、命名、延迟回忆认知评分,MMSE量表总分,EORTC QLQ-C30量表情绪评分显著升高(P<0.05或P<0.01)。MoCA总有效率为58.33%。治疗前后左侧颞极颞中回zALFF值差值与MoCA总分(r=-0.499,P=0.015)及抽象功能差值(r=-0.498,P=0.016)呈负相关。结论调和气血、补心益智法针刺治疗能够改善乳腺癌CRCI患者认知功能,其机制可能与改善海马、杏仁核和颞叶的功能活动及左侧颞极颞中回和右侧小脑后叶的功能连接相关。

关键词：乳腺癌针刺静息态功能磁共振成像化疗相关认知障碍

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Exploring practical methods for detecting k-nonseparability in multipartite quantum states

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 255-256页

作者： Shunlong luo Academy of Mathematics and Systems Science Chinese Academy of Sciences

Quantum entanglement, referred to as “spooky action at a distance” by Einstein, is not only an intriguing and fascinating feature of quantum theory challenging our classical intuitions about locality and correlations, but also has practical and profound implications for quantum technologies. Initially described by Einstein, Podolsky and Rosen, as well as by Schro¨dinger, entanglement now has become a basic and crucial ingredient for both foundational and experimental investigations of the quantum world.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

基于“络以通为用”理论浅析刺络放血治虚

引用

浙江中医药大学学报 2022年第11期46卷 1274-1277页

作者：李子祎罗煊之刘慧林中国中医科学院望京医院康复一科北京100102 首都医科大学附属北京中医医院针灸中心针灸神经调控北京市重点实验室北京中医药大学

[目的]探析“络以通为用”理论,总结刺络放血从络治虚的理论基础,为刺络放血疗法的临床应用拓展思路。[方法]通过查阅古今文献及临床观察,从“络以通为用”理论出发,探讨刺络放血的作用机制及虚证的治疗,并浅析刺络放血从络治虚的理论... 详细信息

[目的]探析“络以通为用”理论,总结刺络放血从络治虚的理论基础,为刺络放血疗法的临床应用拓展思路。[方法]通过查阅古今文献及临床观察,从“络以通为用”理论出发,探讨刺络放血的作用机制及虚证的治疗,并浅析刺络放血从络治虚的理论基础。[结果]《黄帝内经》及张从正、李东垣、杨继洲、傅青主等医家的著作中均有刺络放血用于治疗虚证的记载,但对其作用机制的探讨尚不充分。叶天士在《黄帝内经》“以通为用”理论和通络法的基础上,提出“络以通为用”。从“络以通为用”的角度分析,刺络放血有“以通为补”之效,临床疾病多正虚与邪实并存,虚证可“以通为补”,从络论治。刺络放血治虚的理论依据主要有以清为通平寒热、以消为通理气血、以和为通调阴阳三方面。[结论]刺络放血治虚的机制根本在于“通”,具体可从寒热、气血、阴阳论,络脉理论对其临床应用有重要指导作用。

关键词：刺络放血虚证络脉理论络以通为用以通为补理论探讨

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tilting homeostatic and dyshomeostatic microglial balance in health and disease:transforming growth factor-beta1 as a critical protagonist

引用

Neural Regeneration Research 2025年第10期20卷 2895-2897页

作者： Nicolas Hugues Yu luo Department of Molecular and Cellular Biosciences University of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program University of CincinnatiCincinnatiOHUSA Division of Immunobiology Cincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineCincinnatiOHUSA

Adult microglia,by continuously sensing changes in their environment and communicating with nearly all brain cell types,are considered to be the immune sentinels of the *** the healthy central nervous system(CNS),microglia display a unique molecular homeostatic signature(i.e.,Tmem119,P2ry12,Sall1,Siglech,Gpr34,and Hexb)(Figure 1A).

关键词： Figure signature critical

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of ocean data assimilation on the seasonal forecast of the 2014/15 marine heatwave in the Northeast Pacific Ocean

引用

Atmospheric and Oceanic Science Letters 2025年第1期18卷 24-31页

作者： Tiantian Tang Jiaying He Huihang Sun Jingjia luo Institute for Climate and Application Research(ICAR)/Key Laboratory of Meteorological Disaster Nanjing University of Information Science and TechnologyNanjingChina

A remarkable marine heatwave,known as the“Blob”,occurred in the Northeast Pacific Ocean from late 2013 to early 2016,which displayed strong warm anomalies extending from the surface to a depth of 300 *** study employed two assimilation schemes based on the global Climate Forecast System of Nanjing University of Information Science(NUIST-CFS 1.0)to investigate the impact of ocean data assimilation on the seasonal prediction of this extreme marine *** sea surface temperature(SST)nudging scheme assimilates SST only,while the deterministic ensemble Kalman filter(EnKF)scheme assimilates observations from the surface to the deep *** latter notably improves the forecasting skill for subsurface temperature anomalies,especially at the depth of 100-300 m(the lower layer),outperforming the SST nudging *** excels in predicting both horizontal and vertical heat transport in the lower layer,contributing to improved forecasts of the lower-layer warming during the *** improvements stem from the assimilation of subsurface observational data,which are important in predicting the upper-ocean *** results suggest that assimilating ocean data with the EnKF scheme significantly enhances the accuracy in predicting subsurface temperature anomalies during the Blob and offers better understanding of its underlying mechanisms.

关键词： Seasonal forecast Ocean data assimilation Marine heatwave Subsurface temperature

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

P2Y1 receptor in Alzheimer’s disease

引用

Neural Regeneration Research 2025年第2期20卷 440-453页

作者： Shan luo Yifei Wang Tatsuhiro Hisatsune Department of Integrated Biosciences The University of TokyoKashiwaJapan

Alzheimer’s disease is the most frequent form of dementia characterized by the deposition of amyloid-beta plaques and neurofibrillary tangles consisting of hyperphosphorylated *** amyloid-beta plaques has been a primary direction for developing Alzheimer’s disease treatments in the last ***,existing drugs targeting amyloid-beta plaques have not fully yielded the expected results in the clinic,necessitating the exploration of alternative therapeutic *** evidence unravels that astrocyte morphology and function alter in the brain of Alzheimer’s disease patients,with dysregulated astrocytic purinergic receptors,particularly the P2Y1 receptor,all of which constitute the pathophysiology of Alzheimer’s *** receptors are not only crucial for maintaining normal astrocyte function but are also highly implicated in neuroinflammation in Alzheimer’s *** review delves into recent insights into the association between P2Y1 receptor and Alzheimer’s disease to underscore the potential neuroprotective role of P2Y1 receptor in Alzheimer’s disease by mitigating neuroinflammation,thus offering promising avenues for developing drugs for Alzheimer’s disease and potentially contributing to the development of more effective treatments.

关键词： astrocytes neuroinflammation P2Y1 receptor purinergic receptor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

引用

Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan Sun Lulin Li Jian luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

引用

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng Wang Qinyi Guo Bin Hu Haiwen luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases

引用

Neural Regeneration Research 2025年第11期20卷 3076-3094页

作者： Xinyu Yang Xiangyu Gao Xiaofan Jiang Kangyi Yue Peng luo Department of Neurosurgery Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina

Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological *** to their therapeutic properties and ability to cross the blood–brain barrier,extracellular vesicles are recognized as promising drug delivery vehicles for various neurological conditions,including ischemic stroke,traumatic brain injury,neurodegenerative diseases,glioma,and ***,the clinical application of natural extracellular vesicles is hindered by their limited targeting ability and short clearance from the *** address these limitations,multiple engineering strategies have been developed to enhance the targeting capabilities of extracellular vesicles,thereby enabling the delivery of therapeutic contents to specific tissues or ***,this review aims to highlight the latest advancements in natural and targeting-engineered extracellular vesicles,exploring their applications in treating traumatic brain injury,ischemic stroke,Parkinson's disease,Alzheimer's disease,amyotrophic lateral sclerosis,glioma,and ***,we summarized recent clinical trials involving extracellular vesicles and discussed the challenges and future prospects of using targeting-engineered extracellular vesicles for drug delivery in treating neurological *** review offers new insights for developing highly targeted therapies in this field.

关键词： Alzheimer's disease amyotrophic lateral sclerosis engineered extracellular vesicles glioma ischemic stroke neurological diseases Parkinson's disease psychosis targeted drug delivery traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：