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论香港中文书面语的应用问题--港式中文阅读理解调查问卷分析

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中国语言战略 2017年第1期4卷 1-9,18页

作者：田小琳秦嘉丽山东大学香港社会大学持续教育学院

港式中文是香港中文书面语的一种流行形式,以夹用粤语语句和英语语句为主要特点。本文通过对港式中文阅读理解调查问卷的分析,讨论港式中文流行中存在的问题,谋求港式中文的健康发展。

关键词：港式中文通用中文粤式中文阅读理解调查问卷

Eu_2O_2S的一步溶剂热法合成、表征及性能研究

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人工晶体学报 2018年第7期47卷 1486-1490,1499页

作者：许少俊王越王恺伦任建民连景宝辽宁石油化工大学机械工程学院抚顺113001

以六水硝酸铕、无水乙醇、乙二胺和升华硫为实验原料,采用一步溶剂热法成功合成了Eu2O2S。通过X射线衍射(XRD)、傅里叶变换红外光谱(FT-IR)、场发射扫描电子显微镜(FE-SEM)和紫外-可见吸收光谱(UV-vis absorption)对合成产物进行了表征... 详细信息

以六水硝酸铕、无水乙醇、乙二胺和升华硫为实验原料,采用一步溶剂热法成功合成了Eu2O2S。通过X射线衍射(XRD)、傅里叶变换红外光谱(FT-IR)、场发射扫描电子显微镜(FE-SEM)和紫外-可见吸收光谱(UV-vis absorption)对合成产物进行了表征。XRD和FT-IR表明Eu3+离子与升华硫的摩尔比m、合成温度和合成时间对产物的物相组成有显著的影响。FE-SEM照片显示,随着反应条件的改变,产物形貌由类球状转变为虾片状,对应的颗粒尺寸由20 nm增加至200 nm。UV-vis表明Eu2O2S在以290 nm为中心的紫外光区存在宽带吸收,其禁带宽度约为4.3 e V。

关键词：硫氧化铕一步溶剂热法纳米粉体形貌

扁桃体腺样体切除术在亚洲儿童阻塞性睡眠呼吸暂停/低通气综合征治疗中的病例对照研究(英文)

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中国当代儿科杂志 2006年第1期8卷 1-5页

作者：许志飞卓家良李素轮首都医科大学附属北京儿童医院北京100045

目的评价扁桃体、腺样体切除术对伴有其他上气道疾病的儿童阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)的疗效。方法回顾性总结香港大学附属根德夫人儿童医院睡眠中心1999年5月至2003年5月的儿童OSAHS病例资料。依据睡眠监测结果诊断OSAHS... 详细信息

目的评价扁桃体、腺样体切除术对伴有其他上气道疾病的儿童阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)的疗效。方法回顾性总结香港大学附属根德夫人儿童医院睡眠中心1999年5月至2003年5月的儿童OSAHS病例资料。依据睡眠监测结果诊断OSAHS,再根据体格检查及鼻咽侧位片结果确定这些OSAHS患儿是否存在扁桃体、腺样体肥大。将有扁桃体、腺样体肥大的OSAHS患儿分成手术治疗组和对照组,两组随访观察12个月。对术后仍有OSAHS表现的病例行睡眠内窥镜检查寻找原因。结果88例儿童中,61例诊断为OSAHS,其中39例伴有扁桃体、腺样体肥大,25例接受扁桃体、腺样体切除术治疗。在接受手术治疗的患儿中,手术后随访时氧减指数及最低血氧饱和度较手术前得到显著改善。治疗组中24%随访时仍有OSAHS的表现,而对照组85%的患儿OSAHS表现仍持续存在(OR=15.4,95%置信区间为2.7～87.5)。手术后仍有OSAHS表现的主要原因是肥胖、骨软骨发育不良、上气道解剖结构异常以及维持气道开放的神经肌肉功能异常。结论扁桃体、腺样体切除术在扁桃体、腺样体肥大同时伴有其它上气道疾病的大部分亚洲OSAHS儿童中是有效的。由于上气道结构或维持气道开放的神经肌肉功能异常,可以导致手术后OSAHS症状的残存。对这些患儿,需要做进一步检查明确病因。

关键词：阻塞性睡眠呼吸暂停低通气综合征扁桃体切除术腺样体切除术儿童

Donor ductal anomaly is not a contraindication to right liver lobe donation

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Hepatobiliary & Pancreatic Diseases International 2019年第4期18卷 343-347页

作者： Kenneth SH Chok James YY Fung Wing Chiu Dai Sui Ling Sin ka Wing Ma Albert CY Chan Tan To Cheung Chung Mau Lo Department of Surgery The University of Hong Kong102 Pok Fu Lam RoadHong KongChina State Key Laboratory for Liver Research The University of Hong Kong102 Pok Fu Lam RoadHong KongChina Department of Medicine The University of Hong Kong102 Pok Fu Lam RoadHong KongChina

Background:Data of living-donor liver transplantation(LDLT)suggested that donor ductal anomaly may contribute to postoperative biliary complications in recipients and in *** retrospective study aimed to determine if the occurrence of postoperative biliary stricture in donors or recipients in rightlobe LDLT(RLDLT)is related to donor biliary anatomy ***:We analyzed our RLDLT recipients’clinical data and those of their graft *** recipients were divided into 2 groups:with and without postoperative biliary *** 2 groups were *** primary endpoints were donor biliary anatomy type and postoperative biliary complication incidence;the secondary endpoints were 1-,3-and 5-year graft and patient survival ***:Totally 127 patients were included in the study;25(19.7%)of them developed biliary anastomotic *** these 25 patients,16 had type A biliary anatomy,3 had type B,2 had type C,3 had type D,and 1 had type *** the 127 donors,96(75.6%)had type A biliary anatomy,13(10.2%)had type B,6(4.7%)had type C,10(7.9%)had type D,and 2(1.6%)had type *** stricture was seen in 2 donors,who had type A biliary *** of the recipients or donors developed bile *** association between the occurrence of postoperative biliary stricture and donor biliary anatomy type was found(P=0.527).Conclusions:The incidence of biliary stricture in donors or recipients after RLDLT was not related to donor biliary anatomy *** postoperative complications were similar in whatever type of donor bile duct anatomy,donor ductal anomaly should not be considered a contraindication to donation of right liver lobe.

关键词： Living donor liver transplantation Right liver donation Biliary complications Cholangiograms Ductal anomaly

Comparing 11 early warning scores and three shock indices in early sepsis prediction in the emergency department

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World Journal of Emergency Medicine 2024年第4期15卷 273-282页

作者： Rex Pui Kin lam Zonglin Dai Eric Ho Yin Lau Carrie Yuen Ting Ip Ho Ching Chan Lingyun Zhao Tat ChiTsang Matthew Sik Hon Tsui Timothy Hudson Rainer Department of Emergency Medicine School of Clinical MedicineLi Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina School of Public Health Li Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina Accident and Emergency Department Queen Mary HospitalHong KongChina

BACKGROUND:This study aimed to evaluate the discriminatory performance of 11 vital sign-based early warning scores(EWSs)and three shock indices in early sepsis prediction in the emergency department(ED).METHODS:We performed a retrospective study on consecutive adult patients with an infection over 3 months in a public ED in Hong *** primary outcome was sepsis(Sepsis-3 definition)within 48 h of ED *** c-statistics and the DeLong test,we compared 11 EWSs,including the National Early Warning Score 2(NEWS2),Modified Early Warning Score,and Worthing Physiological Scoring System(WPS),etc.,and three shock indices(the shock index[SI],modified shock index[MSI],and diastolic shock index[DSI]),with Systemic Inflammatory Response Syndrome(SIRS)and quick Sequential Organ Failure Assessment(qSOFA)in predicting the primary outcome,intensive care unit admission,and mortality at different time ***:We analyzed 601 patients,of whom 166(27.6%)developed ***2 had the highest point estimate(area under the receiver operating characteristic curve[AUROC]0.75,95%CI 0.70-0.79)and was significantly better than SIRS,qSOFA,other EWSs and shock indices,except WPS,at predicting the primary ***,the pooled sensitivity and specificity of NEWS2≥5 for the prediction of sepsis were 0.45(95%CI 0.37-0.52)and 0.88(95%CI 0.85-0.91),*** discriminatory performance of all EWSs and shock indices declined when used to predict mortality at a more remote time ***:NEWS2 compared favorably with other EWSs and shock indices in early sepsis prediction but its low sensitivity at the usual cut-off point requires further modification for sepsis screening.

关键词： Sepsis Emergency department Clinical prediction rule Early warning score Shock index

以临床表现筛查阻塞性睡眠呼吸暂停综合征在儿科中的应用

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临床儿科杂志 2005年第1期23卷 21-24页

作者：许志飞卓家良李素轮首都医科大学附属北京儿童医院北京100045 香港大学附属玛丽医院

目的探讨以临床病史、体格检查及颈部侧位X线影像学检查筛查儿童阻塞性睡眠呼吸暂停综合征(obstructivesleepapneasyndrome,OSAS)的可行性。方法在门诊收集有打鼾症状的儿童病例,进行问卷调查、体格检查以及颈部侧位X线检查,以多导睡眠... 详细信息

目的探讨以临床病史、体格检查及颈部侧位X线影像学检查筛查儿童阻塞性睡眠呼吸暂停综合征(obstructivesleepapneasyndrome,OSAS)的可行性。方法在门诊收集有打鼾症状的儿童病例,进行问卷调查、体格检查以及颈部侧位X线检查,以多导睡眠监测仪(PSG)的监测结果作为诊断标准,将患儿分成OSAS和非OSAS组,在两组患儿之间进行临床资料的比较。结果51例鼾症儿童中确诊为OSAS32例。两组患儿的年龄、性别比以及体块指数差异无显著性,而临床表现之间差异有显著性(P<0.001)。如果患儿有8条以上的临床症状、体格检查或影像学的异常,则其患有OSAS的可能性增加,敏感性74%,特异性63%。结论以病史、体格检查及颈部侧位X线检查的结果对患儿进行临床评估,以初步筛查OSAS是可行的。但还需要增加样本量,并改进临床资料的收集工作,以提高筛查的敏感性和特异性。

关键词：儿童阻塞性睡眠呼吸暂停综合征临床表现筛查诊断

Family socioeconomic position and abnormal birth weight:evidence from a Chinese birth cohort

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World Journal of Pediatrics 2019年第5期15卷 483-491页

作者： Si Tu Ao-Lin Wang Mei-Zhen Tan Jin-Hua Lu Jian-Rong He Song-Ying Shen Dong-Mei Wei Min-Shan Lu Shiu lun Au Yeung Hui-Min Xia Xiu Qiu Division of Birth Cohort Study Guangzhou Women and Children's Medical CenterGuangzhou Medical UniversityNo.9 Jinsui RoadZhujiang NewtownTianhe DistrictGuangzhou 510623China Department of Women and Child Health Care Guangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina Department of Neonatal Surgery Guangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina Program on Reproductive Health and the Environment and Bakar Computational Health Sciences Institute University of CaliforniaSan FranciscoCAUSA Department of Child Health Care Guangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina Nuffield Department of Women's and Reproductive Health University of OxfordOxfordUK School of Public Health Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongSARChina Department of Obstetrics and Gynecology Guangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina

Background Birth weight is a strong determinant of infant short-and long-term health *** socioeconomic position(SEP)is usually positively associated with birth *** this association extends to abnormal birth weight or there exists potential mediator is *** We analyzed data from 14,984 mother-infant dyads from the Born in Guangzhou Cohort *** used multi-variable logistic regression to assess the associations of a composite family SEP score quartile with macrosomia and low birth weight(LBW),and examined the potential mediation effect of maternal pre-pregnancy body mass index(BMI)using causal mediation *** The prevalence of macrosomia and LBW was 2.62%(n=392)and 4.26%(n=638).Higher family SEP was associated with a higher risk of macrosomia(OR 1.30,95%CI 0.93-1.82;OR 1.53,95%CI 1.11-2.11;and OR 1.59,95%CI 1.15-2.20 for the 2nd,3rd,and 4th SEP quartile respectively)and a lower risk of LBW(OR 0.69,95%CI 0.55-0.86;OR 0.76,95%CI 0.61-0.94;and OR 0.61,95%CI 0.48-0.77 for the 2nd,3rd,and 4th SEP quartile respectively),compared to the 1st SEP *** found that pre-pregnancy BMI did not mediate the associations of SEP with macrosomia and *** Socioeconomic disparities in fetal macrosomia and LBW exist in Southern *** the results can be applied to other populations should be further investigated.

关键词： Birth cohort Low birth weight Macrosomia Socioeconomic position

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人尿中柯铁宁含量的气相色谱-质谱测定法

中华劳动卫生职业病杂志 2006年第1期24卷 39-41页

作者：曹民张奕伦江朝强林大庆郑家强张维森广州市职业病防治院职业卫生检测中心 510620 香港大学医学院社会医学系英国伯明翰大学公共卫生与流行病学研究所

目的建立利用气相色谱-质谱(GC-MS)联用技术准确测定人尿中柯铁宁含量的方法。方法用β-葡萄糖苷酸酶水解共轭存在的三羟基柯铁宁(THOC)及柯铁宁(COT),以n-丁基乙酸及二氯甲烷混合液(2:1)萃取尿中的柯铁宁成分。应用HP-5MS交联石英毛细... 详细信息

目的建立利用气相色谱-质谱(GC-MS)联用技术准确测定人尿中柯铁宁含量的方法。方法用β-葡萄糖苷酸酶水解共轭存在的三羟基柯铁宁(THOC)及柯铁宁(COT),以n-丁基乙酸及二氯甲烷混合液(2:1)萃取尿中的柯铁宁成分。应用HP-5MS交联石英毛细管柱进行分离,用GCMS 测定其含量。结果该方法检出限为0．02μg/L,回收率>90％,平均相对标准偏差为4．30％。结论 GC-MS法可以准确测定人尿中柯铁宁含量,满足痕量分析的要求,并具有背景值少、快速、准确可靠等特点,已应用于广州生物库老年人队列大样品量的人尿中柯铁宁的研究。

关键词：环境污染,吸烟柯铁宁气-质量光谱测定法

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Cellular & Molecular Immunology 2021年第4期18卷 1005-1015页

作者： Xuezhen Zeng Jingying Zhou Zhewen Xiong Hanyong Sun Weiqin Yang Myth T.S.Mok Jing Wang Jingqing Li Man Liu Wenshu Tang Yu Feng Hector Kwong-Sang W ang Shun-Wa Tsang King-Lau Chow Philip Chun Yeung John Wong Paul Bo-San Lai Anthony Wing-Hung Chan ka Fai To Stephen lam Chan Qiang Xia Jing Xue Xiao Chen Jun Yu Sui Peng Joseph Jao-Yiu Sung Ming Kuang Alfred Sze-Lok Cheng School of Biomedical Sciences The Chinese University of Hong KongHong Kong SARChina lnstitute of Precision Medicine The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Liver Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Pharmacy The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Anatomical and Cellular Pathology The Chinese University of Hong KongHong Kong SARChina Department of Liver Surgery Ren Ji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Gastroenterology The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Division of Life Science Hong Kong University of Science and TechnologyHong Kong SARChina Department of Surgery The Chinese University of Hong KongHong Kong SARChina State Key Laboratory of Translational Oncology The Chinese University of Hong KongHong Kong SARChina Department of Clinical Oncology The Chinese University of Hong KongHong Kong SARChina State Key Laboratory of Oncogenes and Related Genes Stem Cell Research CenterRen Ji HospitalSchool of MedicineShanghai Cancer InstituteShanghai Jiao Tong UniversityShanghaiChina Department of Medicine and Therapeutics The Chinese University of Hong KongHong Kong SARChina State Key Laboratory of Digestive Disease The Chinese University of Hong KongHong Kong SARChina Clinical Trial Unit The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Cancer Center The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina

The liver is an immunologically tolerant organ and a common metastatic site of multiple cancer *** a role for cancer cell invasion programs has been well characterized,whether and how liver-intrinsic factors drive metastatic spread is incompletely ***,we show that aberrantly activated hepatocyte-intrinsic cell cycle-related kinase(CCRK)signaling in chronic liver diseases is critical for cancer metastasis by reprogramming an immunosuppressive *** an inducible liverspecific transgenic model,we found that CCRK overexpression dramatically increased both B16F10 melanoma and MC38 colorectal cancer(CRC)metastasis to the liver,which was highly infiltrated by polymorphonuclear-myeloid-derived suppressor cells(PMNMDSCs)and lacking natural killer T(NKT)*** of PMN-MDSCs in CCRK transgenic mice restored NKT cell levels and their interferon gamma production and reduced liver metastasis to 2.7% and 0.7%(metastatic tumor weights)in the melanoma and CRC models,***,CCRK activated nuclear factor-kappa B(NF-κB)signaling to increase the PMN-MDSC trafficking chemokine C-X-C motif ligand 1(CXCL1),which was positively correlated with liver-infiltrating PMN-MDSC levels in CCRK transgenic ***,CRC liver metastasis patients exhibited hyperaaivation of hepatic CCRK/NF-κB/CXCL1 signaling,which was associated with accumulation of PMN-MDSCs and paucity of NKT cells compared to healthy liver transplantation *** summary,this study demonstrates that immunosuppressive reprogramming by hepatic CCRK signaling undermines antimetastatic *** findings offer new mechanistic insights and therapeutic targets for liver metastasis intervention.

关键词： Cell cycle related kinase liver metastasis liver immune microenvironment myeloid-derived suppressor cell natural killer T cell