Family socioeconomic position and abnormal birth weight:evidence from a Chinese birth cohort
作者机构：Division of Birth Cohort StudyGuangzhou Women and Children's Medical CenterGuangzhou Medical UniversityNo.9 Jinsui RoadZhujiang NewtownTianhe DistrictGuangzhou 510623China Department of Women and Child Health CareGuangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina Department of Neonatal SurgeryGuangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina Program on Reproductive Health and the Environment and Bakar Computational Health Sciences InstituteUniversity of CaliforniaSan FranciscoCAUSA Department of Child Health CareGuangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina Nuffield Department of Women's and Reproductive HealthUniversity of OxfordOxfordUK School of Public HealthLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongSARChina Department of Obstetrics and GynecologyGuangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhouChina
出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)
年 卷 期：2019年第15卷第5期
页 面：483-491页
核心收录：
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
基 金：supported by National Natural Science Foundation of China(Grant Numbers 81673181 81703244 and 81803251)
主 题：Birth cohort Low birth weight Macrosomia Socioeconomic position
摘 要：Background Birth weight is a strong determinant of infant short-and long-term health *** socioeconomic position(SEP)is usually positively associated with birth *** this association extends to abnormal birth weight or there exists potential mediator is *** We analyzed data from 14,984 mother-infant dyads from the Born in Guangzhou Cohort *** used multi-variable logistic regression to assess the associations of a composite family SEP score quartile with macrosomia and low birth weight(LBW),and examined the potential mediation effect of maternal pre-pregnancy body mass index(BMI)using causal mediation *** The prevalence of macrosomia and LBW was 2.62%(n=392)and 4.26%(n=638).Higher family SEP was associated with a higher risk of macrosomia(OR 1.30,95%CI 0.93-1.82;OR 1.53,95%CI 1.11-2.11;and OR 1.59,95%CI 1.15-2.20 for the 2nd,3rd,and 4th SEP quartile respectively)and a lower risk of LBW(OR 0.69,95%CI 0.55-0.86;OR 0.76,95%CI 0.61-0.94;and OR 0.61,95%CI 0.48-0.77 for the 2nd,3rd,and 4th SEP quartile respectively),compared to the 1st SEP *** found that pre-pregnancy BMI did not mediate the associations of SEP with macrosomia and *** Socioeconomic disparities in fetal macrosomia and LBW exist in Southern *** the results can be applied to other populations should be further investigated.
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