检索结果-南通市图书馆

OpenIFEM:A High Performance Modular Open-Source Software of the Immersed Finite Element Method for Fluid-Structure Interactions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2019年第4期119卷 91-124页

作者： Jie Cheng Feimi Yu lucy t.zhang Department of Mechanical Aerospace and Nuclear Engineering Rensselaer Polytechnic InstituteTroyNY12180USA

We present a high performance modularly-built open-source *** is a C++implementation of the modified immersed finite element method(mIFEM)to solve fluid-structure interaction(FSI)*** software is modularly built to perform multiple tasks including fluid dynamics(incompressible and slightly compressible fluid models),linear and nonlinear solid mechanics,and fully coupled fluid-structure *** of open-source software packages are restricted to certain discretization methods;some are under-tested,under-documented,and lack modularity as well as *** is designed and built to include a set of generic classes for users to adapt so that any fluid and solid solvers can be coupled through the FSI *** addition,the package utilizes well-developed and tested *** also comes with standard test cases that serve as software and algorithm *** software can be built on cross-platform,i.e.,Linux,Windows,and Mac OS,using *** parallelization is also implemented for high-performance computing for large-sized *** is documented using Doxygen and publicly available to download on *** is expected to benefit the future development of FSI algorithms and be applied to a variety of FSI applications.

关键词： Immersed finite element method open-source parallelization fluid-structure interaction adaptive mesh refinement

Preface:Simulation of Fluid-Structure Interaction Problems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2019年第4期119卷 1-3页

作者： Zhilin Li X.Sheldon Wang lucy t.zhang Department of Mathematics 2108 SAS HallNC StateRaleighNC 27695USA McCoy School of Engineering Midwestern State University3410 Taft BoulevardWichita FallsTX 76308USA Department of Mechanical Aerospace&Nuclear EngineeringRensselaer Polytechnic Institute1108th St.TroyNY 12180USA

In recent years,there has been a major surge of interest in the development of simulation techniques and strategies for fluid-structure interaction(FSI)problems,mainly driven by a large spectrum of applications in phy... 详细信息

关键词： Structure Preface strategies

A prediction of in vivo mechanical stresses in blood vessels using thermal expansion method and its application to hypertension and vascular stenosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2018年第6期34卷 1156-1166页

作者： Shaoxiong Yang lucy t.zhang Cheng Hua Yunqiao Liu Jingdong tang Xiaobo Gong Zonglai Jiang Shaoxiong Yan91·lucy t.Zhan92 3·Cheng Hua4·Yunqiao Liul·Jingdong Tan95·Xiaobo Gon916.Zonglai Jian971Key Laboratory of Hydrodynamics(Ministry of Education)Department of Engineering MechanicsSchool of NavalArchitectureOcean and Civil EngineeringShanghai JiaoTong UniversityShanghai200240China Department of Mechanical Aerospace and NuclearEngineeringRensselaer Polytechnic InstituteTroyNY12180.USA School of Mechanical Engineering Tianjin University ofScience and TechnologyTianjin300222China Department of Aeronautics and Astronautics FudanUniversityShanghai200433China Vascular Surgery Department Shanghai Pudong HospitalFudan Affiliated Pudong Medical CenterShanghai200120China Collaborative Innovation Center for Advanced Ship and DeepSea Exploration School of Naval ArchitectureOcean andCivil EngineeringShanghai Jiao Tong UniversityShanghai200240China Institute of Mechanobiology and Biomedical Engineering School of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China

Mechanical stimuli play critical roles in cardiovascular diseases,in which in vivo stresses in blood vessels present a great challenge to *** on the structural-thermal coupled finite element method,we propose a thermal expansion method to estimate stresses in multi-layer blood vessels under healthy and pathological *** proposed method provides a relatively simple and convenient means to predict reliable in vivo mechanical stresses with accurate residual *** method is first verified with the opening-up process and the pressure-radius responses for single and multi-layer vessel *** is then applied to study the stress variation in a human carotid artery at different hypertension stages and in a plaque of vascular *** results show that specific or optimal residual stresses exist for different blood pressures,which helps form a homogeneous stress distribution across vessel *** elastic shear stress is identified on the shoulder of the plaque,which contributes to the tearing effect in plaque *** present study indicates that the proposed numerical method is a capable and efficient in vivo stress evaluation of patient-specific blood vessels for clinical purposes.

关键词： Cardiovascular disease In vivo stress Multi-layer vessel structure Hypertension Stenosed vessel

Modeling of Soft tissues Interacting with Fluid (Blood or Air) Using the Immersed Finite Element Method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biomedical Science and Engineering 2014年第3期7卷 130-145页

作者： lucy t. zhang JEC 2049 Department of Mechanical Aerospace and Nuclear Engineering Troy USA

this paper presents some biomedical applications that involve fluid-structure interactions which are simulated using the Immersed Finite Element Method (IFEM). Here, we first review the original and enhanced IFEM methods that are suitable to model incompressible or compressible fluid that can have densities that are significantly lower than the solid, such as air. then, three biomedical applications are studied using the IFEM. Each of the applications may require a specific set of IFEM formulation for its respective numerical stability and accuracy due to the disparities between the fluid and the solid. We show that these biomedical applications require a fully-coupled and stable numerical technique in order to produce meaningful results.

关键词： Biomechanics Fluid-Structure Interactions

Finite Element Simulation of In-Stent Restenosis with tissue Growth Model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biomedical Science and Engineering 2021年第2期14卷 33-47页

作者： Jie Cheng lucy t. zhang Department of Mechanical Aerospace and Nuclear Engineering Rensselaer Polytechnic Institute Troy NY USA

In this study, a finite element simulation of in-stent restenosis (ISR) is conducted to simulate the deployment and expansion of a stent in an occluded artery with a contact model and a mechanics-based growth model. A tissue growth model based on the multiplicative decomposition of deformation is applied to investigate the growth of the plaque and artery wall upon the stent’s implantation. Due to the high stresses at the contact points between the stent struts and the tissue, further tissue injury or restenosis is observed. the simulation results show that after the stent deployment, the von Mises stress is significantly larger in the plaque compared to the artery wall, especially in the region that is in contact with the stent. However, the growth of the plaque and artery tends to even out the stress concentration over time. the tissue growth is found to be more significant near the inner wall than the outer layer. A 0.77 mm restenosis is predicted, which agrees with published clinical observations. the features of the artery growth are carefully analyzed, and the underlying mechanism is discussed. this study is the first attempt to apply finite element analysis to artery restenosis, which establishes a framework for predicting ISR’s occurrence and severity. the results also provide insights into understanding the underlying mechanism of in-stent restenosis.

关键词： Stents In-Stent Restenosis tissue Growth Finite Element Simulation Growth Model

Gap junctions enhance the antiproliferative effect of microrna-124-3p in glioblastoma cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国药理学与毒理学杂志 2016年第10期30卷 1070-1071页

作者： zhang Su-zhi tAO Liang PENG Yue-xia LIU lucy HONG Xiao-ting zhang Yuan WANG Qin Department of Pharmacology Zhongshan School of MedicineSun Yat-Sen University

OBJECtIVE MicroR NA(miR NA)holds promise as a novel therapeutic tool for cancer ***,the transfection efficiency of current delivery systems represents a bottleneck for clinical ***,we demonstrate that gap junctions mediate an augmentative effect on the antiproliferation mediated by mi R-124-3p in U87 and C6 glioblastoma *** the functional inhibition of gap junctions using either si RNA or pharmacological inhibition eliminated the mi R-124-3p-mediated antiproliferation,whereas the enhancement of gap junctions with retinoic acid treatment augmented this mi R-124-3p-mediated antiproliferation.A similar effect was observed in glioblastoma xenograft *** More importantly,patch clamp and co-culture assays demonstrated the transmission of mi R-124-3p through gap junction channels into adjacent *** further exploring the impact of gap junction-mediated transport of mi R-124-3p on mi R-124-3p target pathways,we found that mi R-124-3p inhibited glioblastoma cell growth in part by decreasing the protein expression of cyclindependent kinase 6,leading to cel cycle arrest at the G0/G1phase;moreover,pharmacological regulation of gap junctions affected this cell cycle *** Our results indicate that the″bystander″effects of functional gap junctions composed of connexin 43 enhance the antitumor effect of mi R-124-3p in glioblastoma cells by transferring mi R-124-3p to adjacent cells,thereby enhancing G0/G1cell cycle *** observations provide a new guiding strategy for the clinical application of mi RNA therapy in tumor treatment.

关键词： microRNA miR-124-3p glioblastoma cells cyclin-dependent kinase 6 ″bystander″ effects

On the existence of the compound“Ce_(3)NbO_(7+δ)”prepared under air atmosphere

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2021年第5期39卷 596-599页

作者： Shi-Kuan Sun lucy M.Mottram Neil C.Hyatt Immobilisation Science Laboratory Department of Materials Science and EngineeringThe University of SheffieldSir Robert Hadfield BuildingMappin StreetS13JDUK

the solid state synthesis of the phase"Ce_(3)NbO_(7+δ)",from stoichiometric quantities of CeO_(2)and Nb_(2)O_(5),was investigated under air atmosphere,as previously described by zhang et al.(Journal of Rare Earths,2007,25,730-733),A combination of powder X-ray diffraction,scanning electron microscopy with energy dispersive X-ray analysis,and laboratory Ce L_(3)X-ray absorption spectroscopy,demonstrates the product of the reaction to be a mixture of CeO_(2)and CeNbO_(4).these data,and reexamination of the published X-ray diffraction data of"Ce_(3)NbO_(7+δ)",are consistent with this phase in fact being CeO_(2).No evidence for the formation of a phase of composition"Ce_(3)NbO_(7+δ)"is found,by solid state synthesis under air atmosphere.

关键词： Cerium Niobium XANES XRD Ceramic Rare earths

Using agrophotovoltaics to reduce carbon emissions and global rural poverty

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

the Innovation 2022年第6期3卷 11-12页

作者： Huiming zhang Shan Liang Kai Wu Yueming(lucy)Qiu Yinyin Cai Gabriel Chan Shouyang Wang Dequn Zhou Yi Zhou Zonghao Li School of Management Science and Engineering Nanjing University of Information Science&TechnologyNanjing 210044China School of Finance Central University of Finance and EconomicsBeijing 100081China School of Public Policy University of MarylandCollege ParkMD 20742USA Institute of Atmospheric Environmental Economics Nanjing University of Information Science&TechnologyNanjing 210044China Humphrey School of Public Affairs University of MinnesotaTwin Cities301 S 19th Avenue SMinneapolisMN 55414USA School of Economics and Management University of Chinese Academy of SciencesBeijing 100190China Research Centre for Soft Energy Sciences Nanjing University of Aeronautics and AstronauticsNanjing 211100China

Poverty-alleviation programs using solar energy(PAPSE)are poised to unlock unprecedented capital investments with significant potential to reconcile the energy–poverty–climate nexus.1 these programs are economically feasible because the costs of generating renewable energy have declined precipitously over the past decade;between 2010 and 2019,solar photovoltaiccosts decreased by 82%.Furthermore,the number of annual equivalent-use hours of sunlight in most countries exceeds 1200,meaning that PAPSE approaches are feasible in many places and can be undertaken independently from the power grid.

关键词： generating feasible poverty

Russell body duodenitis with immunoglobulin kappa light chain restriction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2015年第1期7卷 73-76页

作者： William R Munday lucy Harn Kapur Mina Xu Xuchen zhang Department of Pathology Yale University School of Medicine New Haven CT 06516 United States Pathology and Laboratory Medicine Service VA CT Health Care System West Haven CT 06516 United States

Russell bodies are eosinophilic intracytoplasmic globules which are likely the result of disturbed secretion of immunoglobulins that accumulate within the plasma cell. Russell body collections have been identified within the stomach, known as Russell body gastritis. Similar lesions within the duodenum are referred to as Russell body duodenitis, which is rare. Several Russell body gastritis case reports are associated with Helicobacter pylori. However, the etiology of Russell body duodenitis remains unclear. Here we report the first case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.

关键词： Russell body duodenitis Russell bodies Immunoglobulin