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An uncommon cause of abdominal pain in a child: Meckel diverticulum

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Journal of Acute Disease 2017年第5期6卷 229-231页

作者： Anna Chiara Iolanda Contini Tamara Caldaro Giovanni Federici di Abriola Erminia Romeo Valerio Balassone Francesca Rea Filippo Torroni Paola De Angelis Simona Faraci Giulia Angelino Renato Tambucci Luigi dall'Oglio Digestive Surgery and Endoscopy Unit Bambino GesùChildren HospitalIRCCS00165 RomeItaly

Meckel diverticulum, a common congenital anomaly of the small intestine, can be responsible of several complications due to the presence of ectopic gastric mucosa and represents a challenge for diagnosis. We present the case of a 11-year boy suffering from intestinal pain and bleeding in which radiological examinations unexpectedly raised the suspicion of Meckel diverticulum. The diagnosis was confirmed using 99mTc-pertechnetate scintigraphy. At surgery, a fistulous tract between Meckel diverticulum and an inflamed appendix was found. The authors discuss the role of medical nuclear imaging which, notwithstanding its limitations, is of fundamental importance to achieve a correct and timely diagnosis. This is of particular relevance in unusual cases, as the one presented, in which Meckel diverticulum is found concurrently with other intestinal abnormalities.

关键词： Appendix Meckel Scintigraphy

Impact of Therapeutic Education on the Viral Load of HIV Infected Children and Adolescents on Antiretroviral Therapy at the Douala Laquintinie Hospital, Cameroon

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International Journal of Clinical Medicine 2019年第3期10卷 109-121页

作者： Calixte Ida Penda Anne-Cécile Zoung-Kanyi Bissek Serge Clotaire Bilong Loic-Ardin Boupda Cécile Okala Francis Atéba Ndongo Grace dallé Ngondi Else C. Moukoko Eboumbou Louis Richard Njock Olivier Koki Ndombo Clinical Sciences Department Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Laquintinie Hospital Douala Douala Cameroon Faculty of Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon Division of Operational Research in Health Ministry of Public Health of Cameroon Yaoundé Cameroon National HIV Drug Resistance Surveillance and Prevention Working Group Yaoundé Cameroon Groupe Technique Central—CNLS Yaoundé Cameroon Biological Sciences Department Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Clinical Biology Laboratory General Hospital Douala Cameroon Chirurgical Department Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Chantal Biya Foundation Mother-Child Centre Yaoundé Cameroon

Introduction: One of the biggest challenges for HIV-infected adolescents on antiretroviral therapy (ART) is the long-term maintenance of viral suppression, which is the third 90% goal of UNAIDS. Therapeutic Education (TE), process of acquiring abilities and skills that help the patient to live optimally with his illness is one of the strategies that contribute to the achievement of viral suppression through the therapeutic adhesion contract and the follow-up of the patient. The aim of this study was to evaluate the impact of TE on the virologic response of children and adolescents aged 8 - 19 under ART and followed up at the Laquintinie Hospital of Douala (LHD). Method: A cross-sectional study was conducted at the Pediatric Unit of the HIV/AIDS Accredited Treatment Center (ATC) at LHD from February to May 2016. Children and adolescents aged 8 to 19 years on ART, followed in ATC/LHD whose parents had agreed to participate in the study, and who had achieved at least one viral load before and after initiation of TE, were recruited consecutively during routine medical follow-up. Data were collected from patients’ medical records and questionnaires administered to study participants. Results: A total of 198 children and adolescents were included in this study with an average age of 14 years (±3). In this study population, 86.1% of children aged 8 - 10 years had acquired knowledge of the importance of taking medications, 95.4% and 97.3% of adolescents aged 11 - 14 years and 15 - 19 years had knowledge of medication schedules respectively. Among children and adolescents with undetectable viral load prior to initiation of TE, 76.5% maintained an undetectable viral load after initiation of TE. In addition, 72.3% of those whose viral load was detectable before initiation of TE had acquired an undetectable or decreasing viral load after initiation of TE. The only exposure factor significantly associated with maintaining undetectable viral load after initiation of TE was

关键词： HIV Children Adolescents Therapeutic Education Cameroon

酵母Sacchatomycopsis lipolytica的柠檬酸和异柠檬酸分泌

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江苏食品与发酵 1980年第1期 31-38页

作者： Tr’eton B.Le dall M—T. Heslot,H. 徐定邦李文通

我们研究了一株Saccharomycopsis lipolytica生长于正构石腊、葡萄糖或甘油时的柠檬酸和异柠檬酸的分泌。在正构石腊中,这些酸以67∶33的比例分泌,而在葡萄糖或甘油中以92∶8的比例分泌。然而,对所有所应用的碳源,异柠檬酸在细胞库内的... 详细信息

我们研究了一株Saccharomycopsis lipolytica生长于正构石腊、葡萄糖或甘油时的柠檬酸和异柠檬酸的分泌。在正构石腊中,这些酸以67∶33的比例分泌,而在葡萄糖或甘油中以92∶8的比例分泌。然而,对所有所应用的碳源,异柠檬酸在细胞库内的相对量都保持在10%以下。以葡萄糖或甘油为碳源时,柠檬酸和异柠檬酸的同化受阻,而以正构石腊为碳源时不受阻。柠檬酸阻止异柠檬酸同化,这些选择性同化和/或吸收现象可以解释所观察到的在不同碳源上柠檬酸和异柠檬酸分泌比例的差异。

关键词：异柠檬酸百分数细胞库葡萄糖石腊甘油右旋糖己糖多元醇 Sacchatomycopsis lipolytica 柠檬酸分泌酵母

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控制仔猪腹泻需要整体策略

国外畜牧学（猪与禽） 2015年第12期35卷 4-7页

作者：李静万建美孙相俞张涛 Pierre-Stéphane Revy Jacob dall 内江职业技术学院四川农业大学动物营养研究所沂水江泉饲料有限公司 Calcialiment-Vilofoss公司研发部 Vitfoss-Vilofoss公司

仔猪腹泻被视作是由某种特定因素引起的,因此其治疗也可以通过去除这种诱因而实现。根据本系列的上一篇文章来看待仔猪腹泻问题可能得出:为什么不让仔猪的生活环境处于最佳状态呢?本文主要从饲料/营养的角度进行讨论。

关键词：仔猪腹泻控制最佳状态生活环境营养饲料

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Italian survey on non-steroidal anti-inflammatory drugsand gastrointestinal bleeding in children

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World Journal of Gastroenterology 2016年第5期22卷 1877-1883页

作者： Sabrina Cardile Massimo Martinelli Arrigo Barabino Paolo Gandullia Salvatore Oliva Giovanni Di Nardo Luigi dall'Oglio Francesca Rea Gian Luigi de'Angelis Barbara Bizzarri Graziella Guariso Enzo Masci Annamaria Staiano Erasmo Miele Claudio Romano Gastroenterology and Endoscopic Unit Department of PediatricsUniversity of Messina98100 MessinaItaly Department of Translational Medical Science Section of PediatricsUniversity of Naples“Federico II”80131 NaplesItaly Department of Pediatric Gastroenterology Gaslini Institute16148 GenoaItaly Department of Pediatrics and Infantile Neuropsychiatry Pediatric Gastroenterology and Liver UnitSapienza University of Rome00185 RomeItaly Digestive Surgery and Endoscopy Unit Bambino GesùChildren’s Hospital00165 RomeItaly Gastroenterology and Endoscopy Service University of Parma43126 ParmaItaly Unit of Paediatric Gastroenterology Digestive EndoscopyHepatologyand Care of Children with Liver TransplantationDepartment of Women’s and Children’s HealthUniversity Hospital of Padova35128 PadovaItaly Gastrointestinal Endoscopy Azienda Ospedaliera San Paolo University HospitalUniversity of Milan20142 MilanItaly

AIM: To investigate gastrointestinal complications associated with non-steroidal anti-inflammatory drug(NSAIDs) use in ***: A retrospective, multicenter study was conducted between January 2005 and January 2013, with the participation of 8 Italian pediatric gastroenterology centers. We collected all the cases of patients who refer to emergency room for suspected gastrointestinal bleeding following NSAIDs consumption, and underwent endoscopic evaluation. Previous medical history, associated risk factors, symptoms and signs at presentation, diagnostic procedures, severity of bleeding and management of gastrointestinal bleeding were collected. In addition, data regarding type of drug used, indication, dose, duration of treatment and prescriber(physician or selfmedication) were examined. RESULTS: Fifty-one patients, including 34 males, were enrolled(median age: 7.8 years). Ibuprofen was the most used NSAID [35/51 patients(68.6%)]. Pain was the most frequent indication for NSAIDs use [29/51 patients(56.9%)]. Seven patients had positive family history of Helicobacter pylori(H. pylori) infection or peptic ulcer, and 12 had associated comorbidities. Twenty-four(47%) out of 51 patients used medication inappropriately. Hematemesis was the most frequent symptom(33.3%). Upper gastrointestinal endoscopy revealed gastric lesions in 32/51(62%) patients, duodenal lesions in 17(33%) and esophageal lesions in 8(15%). In 10/51(19.6%) patients, a diagnosis of H. pylori gastritis was made. Forty-eight(94%) patients underwent medical therapy, with spontaneous bleeding resolution, while in 3/51(6%) patients, an endoscopic hemostasis was ***: The data collected in this study confirms that adverse events with the involvement of the gastrointestinal tract secondary to NSAID use are also common in

关键词： Hematemesis Gastrointestinal bleeding non-steroidal anti-inflammatory drug Melena Pediatrics

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一个地面天文观测的远红外光度计

天文学报 1985年第2期 180-186页

作者：谢光中 C.Ceccarelli L.Pietranera G.dall'Oglio G.Ferri S.Radford 中国科学院云南天文台意大利罗马大学物理系意大利罗马大学物理系意大利国家研究委员会大气物理所意大利国家研究委员会行星际物理所美国华盛顿大学天文系

本文作者研制成功一个适用于毫米波段大气窗口的红外光度计,由锗-镓热辐射探测器组成,工作温度在1.0K,输入量AW=0.3cm2sr,等效功率为1mk/Hz1/2。用两个金属网格建立了两个窗口,频率分别为10cm-1和5cm-1。这个光度计的特点是:（1）灵敏... 详细信息

本文作者研制成功一个适用于毫米波段大气窗口的红外光度计,由锗-镓热辐射探测器组成,工作温度在1.0K,输入量AW=0.3cm2sr,等效功率为1mk/Hz1/2。用两个金属网格建立了两个窗口,频率分别为10cm-1和5cm-1。这个光度计的特点是:（1）灵敏度高到足以达到大气辐射的量子涨落的极限,但又特别简单易于控制。（2）这个系统不需要使用外部的泵,因此易于在望远镜的焦平面上操作。

关键词：热辐射探测器等效功率远红外光度计低温恒温器低温设备天文观测

儿童期因素及种族间差异对成年后脉搏波传导速度的影响

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中华高血压杂志 2016年第6期24卷 574-574页

作者：刘莉叶鹏 Cruickshank JK Silva MJ Molaodi OR Enayat ZE Cassidy A Karamanos A Read UM Faconti L dall P Stansfield B Harding S

目前对于脉搏波传导速度（主动脉僵硬度评估指标）的早期决定因素知之甚少。该研究探索多种族队列研究中童年时期曾测量2次的指标,尤其是体质量指数、血压和客观评估的体力活动对成年后主动脉僵硬度的作用。

关键词：脉搏波传导速度动脉僵硬度体力活动童期队列研究体质量动脉造影客观评估亚组设备检测

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Cryoglobulinemia in elderly patients with HCV-related chronic hepatitis

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2010年第2期1卷 72-74页

作者： Francesco Giuseppe Foschi Anna Chiara dall'Aglio Arianna Lanzi Giorgio Marano Sara Savini Pietro Andreone Mauro Bernardi Giuseppe Francesco Stefanini Department of Internal Medicine Faenza Hospital Department of Clinical Medicine Bologna University

Hepatitis C virus(HCV) infection affects about 3% of the world's population and often leads to chronic liver *** some industrialized countries,HCV prevalence increases with age,but the optimal management of older patients has not been accurately *** infection can also lead to lymphoproliferative disorders,the most common being mixed cryoglobulinemia(MC),and also for this condition that frequently affects elderly patients,the optimal therapeutic strategy is still *** report the case of a 77-year-old Caucasian woman with HCV-related chronic hepatitis and cutaneous manifestations consisting of urticaria and pruritus related to MC resistant to *** patient underwent a treatment with interferon and *** a treatment led to early biochemical and virological response associated with the resolution of cryoglobulinemia and cutaneous *** the end of treatment,HCV replication relapsed,but cryoglobulinemia and cutaneous symptoms did not *** the absence of definite treatment guidelines in this particular context,our experience suggests that the presence of symptoms related to HCV-infection that deeply affect patient quality of life warrants antiviral therapy even beyond the age limits that currently exclude patients from treatment.

关键词： Cryoglobulinemia Elderly patients Hepatitis C virus chronic hepatitis Antiviral treatment

ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy

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World Journal of Gastrointestinal Endoscopy 2014年第7期6卷 318-323页

作者： Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T dall’Oglio L Filippo Torroni Erminia Romeo Francesca Rea Paola De Angelis Francesca Foschia Simona Faraci Giovanni Federici di Abriola Anna Chiara Contini Tamara Caldaro Luigi Dall’Oglio Department of Surgery and Transplantation Digestive Surgery and Endoscopy Unit Bambino Gesù Children’s Hospital IRCCS 00165 Rome Italy

AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each ***: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS

关键词： Peutz-Jeghers 症候群汽球帮助了 enteroscopy Polypectomy