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Global prevalence and gender inequalities in at least 60 min of self-reported moderate-to-vigorous physical activity 1 or more days per week:An analysis with 707,616 adolescents

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Journal of Sport and Health Science 2024年第5期13卷 709-716页

作者： Raphael H.O.Araujo AndrúO.Werneck Clarice L.Martins luciana L.Barboza Rafael M.Tassitano Nicolas Aguilar-Farias Gilmar M.Jesus Robinson Ramírez-Véelez Riki Tesler Adewale L.Oyeyemi Ellen C.M.Silva Robert G.Weaver Mark S.Tremblay Javier Brazo-Sayavera Grégore I.Mielke Danilo R.P.Silva Graduation Program in Health Sciences Londrina State University(UEL)Londrina 86057-970Brazil Center for Epidemiological Research in Nutrition and Health Department of NutritionSchool of Public HealthUniversidade de Sao Paulo(USP)Sao Paulo 01246-904Brazil Department of Physical Education Federal University of ParaıbaParaıba 58051-900Brazil Research Centre of Physical Activity Health and LeisureFaculty of SportsLaboratory for Integrative and Translational Research in Population Health(ITR)University of PortoPorto 4500Portugal Postgraduate Program in Physical Education University of BrasıliaBrasılia 70910-900Brazil Department of Kinesiology and Community Health University of Illinois at Urbana-ChampaignChampaignIL 61801-3841USA Department of Physical Education Sports and RecreationUniversidad de La FronteraTemuco 4680000Chile Department of Health State University of Feira de SantanaFeira de Santana 44036-900Brazil Navarrabiomed Hospital Universitario de Navarra(HUN)Navarra Institute for Health Research(IdiSNA)Universidad Publica de Navarra(UPNA)Pamplona 31006Spain Facultad de Ciencias de la Educacion Unidad Central del Valle del Cauca(UCEVA)TuluaValle del Cauca 763022Colombia Health Management Department Faculty of Heath sciencesAriel UniversityAriel 40700Israel College of Health Solutions Arizona State UniversityPhoenixAZ 85004USA Arnold School of Public Health University of South CarolinaColumbiaSC 29208USA Healthy Active Living and Obesity Research Group Children’s Hospital of Eastern Ontario Research InstituteOttawaON K1H 8L1Canada Department of Pediatrics University of OttawaOttawaON K1H 8L1Canada Department of Health Sciences Carleton UniversityOttawaON K1S 5B6Canada Department of Sports and Computer Science Universidad Pablo de Olavide(UPO)Seville 41013Spain Centro Universitario Regional Noreste Universidad de la RepublicaRivera 40000Uruguay School of Public Health The University of QueenslandBrisbaneQLD 4006Australia Department of Physical Education

Background:Guidelines recommend that adolescents should accumulate an average of 60 min per day of moderate-to-vigorous physical activity(MVPA).However,using only this cut-off could hide important *** instance,from a population-level point of view,increasing physical activity for those with no or low physical activity could provide more health benefits than increasing physical activity for those with intermediate ***,including a more sensitive cut-point of≥1 days per week could be an additional strategy for identifying those with low access/opportunities for physical activity ***,the current study aims to estimate the prevalence of≥60 min of MVPA≥1 days per week among adolescents globally,and to describe any relevant gender ***:We used representative datasets from 146 countries/territories collected between 2003 and *** was *** were grouped into younger(≤14 years old)and older(>14 years old)*** Poisson regression models were used to identify the relative differences in≥60 min of MVPA≥1 days per week between boys and girls,and random-effects meta-analysis models were used to identify the pooled *** were stratified by country and ***:Approximately 80%of both younger and older adolescents reported≥60 min of MVPA≥1 days per *** prevalence was≥94%in Europe and Central Asia and North America,while the estimates for the other regions were14y)=1.09(95%CI:1.08-1.10)).Conclusion:Approximately 8 out of 10 adolescents reported accumulating≥60 min of MVPA≥1 days per week,with notable differences between *** differences were observed in several countries,especially among the oldest *** fo

关键词： Global School-based Student Health Survey Health Behaviour Among School-aged Children survey Inequality Surveillance Youth

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High resolution manometric findings in patients with Chagas' disease esophagopathy

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Asian Pacific Journal of Tropical Medicine 2012年第2期5卷 110-112页

作者： luciana C Silva Fernando PP Vicentine Fernando AM Herbella Department of Surgery Escola Paulista de MedicinaFederal University of Sao PauloSao PauloBrazil

Objective:To describe high resolution manometry features of a population of symptomatic- patients with Chagas’ disease esophagopathy(CDE).Methods:Sixteen symptomatic dysphagic patients with CDE[mean age(54.81±13.43) years,10 women]were included in this *** patients underwent a high resolution ***:Mean lower esophageal sphincter(LES) extension was(3.02±1.17) cm with a mean basal pressure of(15.25±7.00) *** pressure was(14.31±9.19) *** was found in all 16 *** with minimal esophageal pressurization(type I) was present in 25%of patients and achalasia with esophageal compression(type 2) in 75%,according to the Chicago *** esophageal sphincter(UES) mean basal pressure was(97.96±54.22) mmHg with a residual pressure of(12.95±6.42) ***:Our results show that LES was hypotensive or normotensive in the majority of the *** relaxation was found in a minority of our *** was seen in 100%of *** had impaired relaxation in a significant number of patients. Further clinical study is needed to investigate whether manometric features can predict outcomes following the studies of idiopathic achalasia..

关键词： Achalasia Chagas disease High resolution manometry

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An overview of plant-autochthonous microorganisms and fermented vegetable foods

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Food Science and Human Wellness 2020年第2期9卷 112-123页

作者： Sebastian Torres Hernan Veron luciana Contreras Maria I.Isla Instituto de Bioprospeccion y Fisiologia Vegetal(INBIOFIV)–CONICET TucumanArgentina Facultad de Ciencias Naturales e IML Universidad Nacional de TucumanTucumanArgentina

Fermented plant-based foods and beverages constitute foods of high nutritional and functional value with appreciated health beneficial *** represent a natural and sustainable alternative to counteract the large wastage of vegetables and fruits due to their short shelf ***,the use of controlled fermentation process using autochthonous microorganisms adapted to their vegetable matrix is preferred instead of traditionally spontaneous fermentation to designing fermented vegetable foods with the desirable sensory,technological,nutritional and functional *** review summarizes the autochthonous microorganisms selected as starters for the successful fermentation of vegetables and *** main beneficial properties of autochthonous starters and fermented vegetable products with a focus on human health are revised.

关键词： Plant-autochthonous Microorganisms Fermented vegetable foods Functional foods Lactic acid bacteria Probiotics Probiotic

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The omnivorous predator Macrolophus pygmaeus,a good candidate for the control of both greenhouse whitefly and poinsettia thrips on gerbera plants

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Insect Science 2020年第3期27卷 510-518页

作者： Ada Leman Barbara L.Ingegno luciana Tavella Arne Janssen Gerben J.Messelink Wageningen University&Research Business Unit Greenhouse HorticultureBleiswijkthe Netherlands Dipartimento di Scienze Agrarie Forestall e Alimentari(DISAFA)ULF Entomologia Generate e ApplicataUniversity of TorinoGrugliasco(TO)Italy IBED Department of Evolutionary and Population BiologyUniversity of AmsterdamAmsterdamthe Netherlands

The poinsettia thrips Echinothrips americanus Morgan is a relatively new pest that has spread rapidly worldwide and causes serious damage in both vegetable and ornamental *** this study,we investigated if and how effective this pest can be controlled in gerbera by the omnivorous predator Macrolophus pygmaeus(Rambur).Because herbivores on plants can interact through a shared predator,we also investigated how poinsettia thrips control is affected by the presence of the greenhouse whitefly Trialeurodes vaporariorum(Westwood),a pest that commonly coexists with *** in *** laboratory studies,we found that the predator *** fed on both pests when offered *** tests showed a clear preference of the predators for plants infested by whiteflies but not by *** a greenhouse experiment,densities of both pests on single gerbera plants were reduced to very low levels by the predator,either with both pests present together or ***,predator‐mediated effects between whiteflies and thrips played only a minor *** plant feeding of the shared predator probably reduced the dependence of predator survival and reproduction on the densities of the two pests,thereby weakening potential predator‐mediated ***,*** is a good candidate for biological control of both pests in ***,further research is needed to investigate pest control at larger scales,when the pests can occur on different plants.

关键词： apparent competition biological control Echinothrips americanus pest interactions prey preference Trialeurodes vaporariorum

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Perceptions About Climate Change in the Brazilian Civil Defense Sector

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International Journal of Disaster Risk Science 2022年第5期13卷 664-674页

作者： Victor Marchezini luciana Resende Londe Eloisa Beling Loose Silvia Midori Saito JoséA.Marengo Cemaden-National Center for Monitoring and Early Warning of Natural Disasters São Paulo 12.247-016Brazil Natural Hazards Center Institute of Behavioral ScienceUniversity of Colorado BoulderBoulderCO 80309USA Programa de Pós-Graduação em Desastres Naturais ICT/Unesp-CemadenSão Josédos Campos 12247-004Brazil Environmental Journalism Research Group Universidade Federal do Rio Grande do Sul(UFGRS)Porto Alegre 90035-007Brazil Programa de Pós-Graduação em Desastres Naturais Universidade Federal de Santa CatarinaFlorianópolis 88.040-900Brazil

Few studies have analyzed climate change perceptions in the disaster risk management *** research aimed to understand how civil defense experts are dealing with the climate change topic:what they learn and think *** online survey was conducted between October and December 2021 with 1,063 participants from civil defense agencies in *** findings indicate:(1) most(80.6%) civil defense officers completely agreed that climate change will cause additional challenges to disaster risk management,while 10.1% stated that they are prepared to deal with it;(2) one quarter of the respondents(26.3%) completely agreed that they easily understand the information about climate change,but trust in the sources of information is a challenge-52.4% completely agreed and 40.5% partially agreed with information provided by scientists,but the levels of trust were reduced when referring to governments and press;and(3) about 30% of the respondents thought that civil defense work is associated with the Sustainable Development Goals(SDGs),despite SDGs 11 and 13 being related to disasters and climate *** identification of civil defense’ perceptions on climate change is an important step in seeking pathways for increasing capacity building to achieve disaster risk reduction and climate change adaptation.

关键词： Brazil Capacity building Disaster risk management Emergency management Risk governance Risk perception

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Is the EGFR pathway relevant for the pathogenesis but not for treatment of acute myeloid leukemia?

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Journal of Cancer Metastasis and Treatment 2021年第1期7卷 765-774页

作者： luciana Yamamoto de Almeida Eduardo Magalhães Rego Center for Cell-based Therapy University of Sao PauloRibeirao PretoSao Paulo CEP 14051-140Brazil Hematology Division LIM31Faculdade de MedicinaUniversity of Sao PauloSao Paulo CEP 05403-000Brazil.

Despite intense research and the development of several new chemotherapeutics,the prognosis for specific subsets of acute myeloid leukemia(AML)has not improved ***,the investigation of signaling pathways associated with the pathogenesis and progression of AML has become a source for the discovery of more effective *** epidermal growth factor receptor(EGFR)belongs to the HER family of tyrosine kinase(TK)receptors and is involved in the progression of a variety of solid *** the expression of members of the HER family appears to be limited to epithelial tissues and derived neoplasms,there is evidence demonstrating their role in hematopoiesis and hematological *** AML,preclinical studies and two anecdotal cases of response to EGFR TK inhibitors(TKI)supported the EGFR signaling pathway as a potential therapeutic ***,the presence of EGFR ligands in the bone marrow microenvironment has been shown to play pathological and regenerative/protective roles in ***,data reporting the expression of EGFR in AML remain controversial and the EGFR pathway inhibition in AML patients has demonstrated limited clinical *** studies are required to determine the relevance of the EGFR pathway in AML biology and which patients may benefit from using EGFR TKI or other drugs that target TK receptors.

关键词： Acute myeloid leukemia epidermal growth factor receptor EGFR ligands EGFR tyrosine kinase inhibitors gefitinib erlotinib

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Planktonic foraminifera as bio-indicators for monitoring the climatic changes that have occurred over the past 2000 years in the southeastern Tyrrhenian Sea

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Integrative Zoology 2014年第4期9卷 542-554页

作者： Fabrizio LIRER Mario SPROVIERI Mattia VALLEFUOCO luciana FERRARO Nicola PELOSI Laura GIORDANO Lucilla CAPOTONDI Institute for Coastal Marine Environment National Research CouncilNaplesItaly Institute for Coastal Marine Environment National Research CouncilTorretta Granitola(Fraz.Campobello di MazaraTp)Italy Istituto Scienze Marine Istituto per l’Ambiente Marino CostieroConsiglio Nazionale delle RicercheConsiglio Nazionale delle RicercheBolognaItaly and Institute of Marine SciencesNational Research CouncilBolognaItaly

A high-resolution integrated study has been performed in a super-expanded marine record(sedimentation rate spanning from 11 cm/100 years to 20 cm/100 years)from the continental shelf area of the southeastern Tyrrhenian *** foraminiferal distribution illustrates 6 major environmental changes during the past 2000 years:(i)the Roman Period-Dark Age transition(from herbivorous-opportunistic to carnivorous species);(ii)the Dark Age-MCA transition(from carnivorous to herbivorous-opportunistic species);(iii)the Medieval Classic Anomaly-Little Ice Age transition(a further and definitive change from carnivorous to herbivorous-opportunistic species);(iv)the period during the Maunder event between approximately 1720 AD and 1740 AD(turnover from the carnivorous planktonic foraminifer Globigerinodes ruber to the herbivorous-opportunistic planktonic foraminifer Turborotalita quinqueloba);(v)the Industrial Period(dominance of herbivorous-opportunistic planktonic foraminifera);and(vi)the Modern Warm Period at approximately 1940 AD(the last turnover in favor of herbivorous-opportunistic planktonic foraminifers,associated with an increase in benthic foraminifera).Our studies lead us to link this latter feature to an anthropogenic impact associated with the damming of Sele River(Salerno Gulf)at 1934 AD,which induced a change in the sediment input with a strong decrease in coarse-grained fraction and a probable alteration in nutrient ***δ^(18)O_(***) record of the past 2000 years shows the alternation of warm/wet and cold/dry events related to the Roman Period,the Dark Age,the Medieval Classic Anomaly,the Little Ice Age,the Industrial Period and the Modern Warm *** 5 evidentδ^(18)O_(***) oscillations(between approximately 1325 AD and 1940 AD)coincide with the 5 minima in the solar activity record(Wolf,Spörer,Maunder,Dalton and Damon events).

关键词： Mediterranean Basin oxygen stable isotopes planktonic foraminifera southeastern Tyrrhenian Sea

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Seed-Specific Expression of Apolipoprotein A-IMilano Dimer in Engineered Rice Lines

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Rice science 2023年第6期30卷 587-597页

作者： Serena REGGI Elisabetta ONELLI Alessandra MOSCATELLI Nadia STROPPA Matteo DELL’ANNO Kiril PERFANOV luciana ROSSI Department of Veterinary Medicine and Animal Science University of MilanLodi 26900Italy Department of Biosciences University of MilanMilan 20133Italy Plantechno Srl Casalmaggiore 26040Italy

Apolipoprotein A-IMilano(ApoA-IM)has been shown to significantly reduce coronary atherosclerotic ***,the preparation of cost-effective pharmaceutical formulations of ApoA-IM is limited by the high cost and difficulty of purifying the protein and producing the highly effective dimeric *** aim of this study was to create an expression cassette that specifically drives the expression of dimeric ApoA-IM in the protein bodies of rice *** ApoA-IM protein under control of the 13 kDa prolamin promoter is expressed exclusively in its dimeric form within the seeds,and immunocytochemical and immunogold analyses confirmed its expression in different caryopsis tissue such as seed coat,aleurone cell and endosperm,particularly in amyloplast and storage vacuoles.A plant-based ApoA-IM production system offered numerous advantages over current production systems,including the direct production of the most therapeutically effective dimeric ApoA-IM forms,long-term protein storage in seeds,and ease of protein production by simply growing ***,seeds had the potential to serve as a costeffective source of therapeutic ApoA-IM.

关键词： apolipoprotein A-IMilano engineered plant immunofluorescence immunogold analysis rice seed-specific promoter

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Analysis of the histologic features in the differential diagnosis of intrahepatic neonatal cholestasis

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World Journal of Gastroenterology 2009年第4期15卷 478-483页

作者： Maria Angela Bellomo-Brandao Cecilia AF Escanhoela luciana R Meirelles Gilda Porta Gabriel Hessel Department of Pediatrics Faculty of Medical SciencesState University of Campinas(UNICAMP) Department of Pathology Faculty of Medical SciencesState University of Campinas(UNICAMP) Department of Pediatrics Children's Institute of Medical School of the University of So Paulo(USP)

AIM:To compare the histologic features of the liver in intrahepatic neonatal cholestasis(IHNC)with infectious,genetic-endocrine-metabolic,and idiopathic etiologies. METHODS:Liver biopsies from 86 infants with IHNC were *** inclusion criteria consisted of jaundice beginning at 3 mo of age and a hepatic biopsy during the 1st year of *** following histologic features were evaluated:cholestasis,eosinophilia,giant cells,erythropoiesis,siderosis,portal fibrosis,and the presence of a septum. RESULTS:Based on the diagnosis,patients were classified into three groups:group 1(infectious;n=18),group 2(genetic-endocrine-metabolic;n=18),and group 3(idiopathic;n=50).There were no significant differences with respect to the following variables:cholestasis,eosinophilia,giant cells,siderosis,portalfibrosis,and presence of a septum.A significant difference was observed with respect to erythropoiesis,which was more severe in group 1(Fisher's exact test,P=0.016). CONCLUSION:A significant difference was observed in IHNC of infectious etiology,in which erythropoiesis was more severe than that in genetic-endocrine-metabolic and idiopathic etiologies,whereas there were no significant differences among cholestasis,eosinophilia,giant cells,siderosis,portal fibrosis,and the presence of a septum.

关键词： Intrahepatic cholestasis Liver histopathol-ogy Neonatal jaundice Neonatal liver disease

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An internal control applied to RT-PCR detection of HCV and HIV-1 in human pooled plasma and plasma-derived medicinal products

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BIOCELL 2015年第2期39卷 15-23页

作者： Gonzalo RODRÍGUEZ-LOMBARDI luciana REYNA María Susana VITALI Susana GENTI-RAIMONDI Laboratorio de Hemoderivados Universidad Nacional de Córdoba Centro de Investigaciones en Bioquímica Clínica e Inmunología Departamento de Bioquímica ClínicaFacultad de Ciencias QuímicasUniversidad Nacional de Córdoba-Consejo Nacional de Investigaciones Científicas y TécnicasX5000HUA CórdobaArgentina

A competitive internal control(IC)adapted to RT-PCR in-house assay was developed for HCV RNA detection in human pooled ***,it was applied in a multiplex RT-PCR for the HIV-1 and HCV RNA screening in human pooled plasma and plasma-derived products.A 258-bp PCR product from the 5´non-coding region of HCV genome was obtained.A competitive IC template was constructed by inserting a 52-bp double strand sequence into the NheI site of the 258-bp *** sequence was cloned and the obtained plasmid was used to generate a synthetic *** IC/RNA was incorporated in in-house HCV and/or HIV PCR technique to monitor the efficiency of extraction,reverse transcription,and PCR amplification *** was also used to detect all major genotypes of HCV and HIV-1 strains with similar *** detection limit of the assay for HCV and HIV-1 was 52.7 IU/mL and 164.2 IU/mL,*** techniques have been evaluated in international programs of external quality assurance with highly satisfactory *** IC is an essential reagent in PCR techniques to detect and identify HCV and HIV-1 in pooled plasma samples involved in the manufacture of plasma-derived products as well as in the field of clinical microbiology with limited resources.

关键词： HCV HIV internal control RT-PCR

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