检索结果-南通市图书馆

Molecular Structure of Feeds in Relation to Nutrient Utilization and Availability in Animals： A Novel Approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2017年第5期3卷 726-730页

作者： Peiqiang Yu luciana L. Prates Department of Animal and Poultry Science College of Agriculture and Bioresources University of Saskatchewan Saskatoon SK S7N 5A8 Canada

The invention and development of new research concepts, novel methodologies, and novel bioanalytical techniques are essential in advancing the animal sciences, which include feed and nutrition science. This article introduces a novel approach that shows the potential of advanced synchrotron-based bioanalytical technology for studying the effects of molecular structural changes in feeds induced by various treatments （e.g., genetic modification, gene silencing, heat-related feed processing, biofuel processing） in relation to nutrient digestion and absorption in animals. Advanced techniques based on synchrotron radiation （e.g., synchrotron radiation infrared microspectroscopy （SR-IMS） and synchrotron radiation X-ray techniques） have been developed as a fast, noninvasive, bioanalytical technology that, unlike traditional wet chemistry methods, does not damage or destroy the inherent molecular structure of the feed. The cutting-edge and advanced research tool of synchrotron light （which is a million times brighter than sunlight） can be used to explore the inherent structure of biological tissue at cellular and molecular levels at ultra-high spatial resolutions. In conclusion, the use of recently developed bioanalytical techniques based on synchrotron radiation along with common research techniques is leading to dramatic advances in animal feed and nutritional research.

关键词： Inherent molecular structure Synchrotron radiation applications Molecular nutrition Feed science technology Molecular imaging Nutrient digestion and absorption

Mitochondrial DNA alterations in the progression of gastric carcinomas:Unexplored issues and future research needs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第43期20卷 16159-16166页

作者： luciana Rigoli Rosario Alberto Caruso Department of Pediatrics School of MedicineUniversity of Messina98122 MessinaItaly Department of Human Pathology School of MedicineUniversity of Messina98122 MessinaItaly

Gastric cancer is the second most frequent cause of cancer death *** infected with Helicobacter pylori(***)are at increased risk of gastric *** induces genomic instability in both nuclear and mitochondrial(mt)DNA of gastric epithelial *** in mt DNA represent an early event during gastric tumorigenesis,and thus may serve as potential biomarkers for early detection and prognosis in gastric *** review article summarizes the mt DNA mutations that have been reported in gastric carcinomas and their precancerous *** research topics,such as the role of mt DNA alterations in an alternative pathway of gastric carcinogenesis,are identified and directions for future research are suggested.

关键词： Gastric carcinoma Precancerous lesions Histopathology mtDNA Molecular biology

Inflammatory bowel disease in pediatric and adolescent patients:A biomolecular and histopathological review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第30期20卷 10262-10278页

作者： luciana Rigoli Rosario Alberto Caruso Department of Pediatrics University of MessinaI-98125 MessinaItaly Department of Human Pathology University of MessinaI-98125 MessinaItaly

Crohn’s disease (CD) and ulcerative colitis (UC) are the two main forms of inflammatory bowel disease (IBD) with both overlapping and distinct clinical, pathological and biomolecular features. It has been suggested that pediatric IBD is a distinct disease entity, with probably different disease *** aim of this study is to review and summarize the evolution of the current concept of pediatric IBD. The results of this review reinforce the idea that pediatric CD and UC may be further classified in various clinicopathologic entities. For clinicians and pathologists convenience, practical algorithms for the distinction of the various subphenotypes of pediatric IBD are also provided.

关键词： Pediatric inflammatory bowel disease Crohn's disease Ulcerative disease Histopathology Molecular biology

Development of waste-to-energy through integrated sustainable waste management:the case of ABREN WtERT Brazil towards changing status quo in Brazil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Waste Disposal and Sustainable Energy 2023年第3期5卷 295-308页

作者： Yuri Schmitke Almeida Belchior Tisi Flavio arantes Matos Maria Luisa N.M.Carneiro Waste to Energy Research and Technology Council—WtERT Brasil Distrito FederalBrasília71316-109Brazil Waste to Energy Research and Technology Council—WtERT Brasil Ribeirão PretoSão PauloBrazil Waste to Energy Research and Technology Council—WtERT Brasil Rio de JaneiroBrazil

In the context of circular economy,it is known that once waste is generated,it should be subject to proper treatment for recovering material or energy before being *** countries worldwide,especially developing countries such as Brazil,have been struggling to effectively apply sustainable waste management in municipalities and still rely on dumpsites and unsuitable ***,a weak legal framework,lack of financial resources and poor infra-structure as well as pressure from organizations profiting from the expansion of landfills are some factors contributing to the preservation of the negative status quo:the“landfill culture”.Material recovery,i.e.,recycling and composting,is applied to less than 5%of Brazilian municipal waste,while 95%is disposed of in landfills or *** this context,ABREN WtERT(Waste-to-Energy Research and Technology Council)Brazil was created in 2019 as the first permanent organization formed to promote the development of energy and material recovery from waste focused on the waste-to-energy(WTE)*** this paper,the strategy proposed and implemented by the organization towards changing the status quo in Brazil through an integrated sustainable waste management approach is *** proposed strategy integrates the concepts of Sustainability and Circular Economy for minimizing landfill disposal(avoiding methane emissions)and maximizing material/energy *** others,the approach focuses on changing the public opinion regarding thermal treatment facilities,mainly incinerators,which has been wrongly linked to pollution,excessive public expenditures and considered a harm to the recycling *** activities performed by ABREN include engaging public and private institutions,enhancing education,leading the publication of research and business studies,gathering industry members and academy experts,as well as creating strategic alliances with players around the *** a result,within a few years,major

关键词： Integrated Sustainable Waste Management(ISWM) Waste-to-energy(WTE) Municipal solid waste(MSW) Energy recovery

Oligodendrocytes in a dish for the drug discovery pipeline:the risk of oversimplification

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第2期16卷 291-293页

作者： Vito Antonio Baldassarro luciana Giardino Laura Calzà Health Science and Technologies Interdepartmental Center for Industrial Research(HST-ICIR) University of BolognaBolognaItaly Department of Veterinary Medical Sciences University of BolognaIRET FoundationBolognaItaly Department of Pharmacy and Biotechnology University of BolognaMontecatone Rehabilitation InstituteBolognaItaly

Myelination,remyelination and demyelination:modeling the in vitro drug discovery pipeline:Demyelination is a multifactorial event occurring in diseases primarily involving myelin forming cells(oligodendrocytes,OLs)and their precursors(oligodendrocyte precursor cells,OPCs)such as multiple sclerosis,but is also involved in the pathology of other central nervous system(CNS)injuries and diseases,such as neonatal encephalopathy。

关键词： cytes injuries diseases

Rapid acupuncture for musculoskeletal pain in the emergency room of the Hospital Servidor Publico Estadual, Brazil: A quasi-experimental study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2020年第4期18卷 313-318页

作者： luciana Aikawa Alexandre Massao Yoshizumi Mirian Matsura Shirassu Marcia Kiyomi Koike Programa de Pós-Graduação em Ciências da Saúde Instituto de Assistência Médica ao Servidor Público Estadual(IAMSPE)Vila ClementinoSão PauloSP 04029-000Brazil Associação Médica Brasileira de Acupuntura Vila MarianaSão PauloSP 04011-002Brazil

Objective:To compare differences in self-reported musculoskeletal pain before and after receiving rapid acupuncture for pain at an outpatient emergency ***:Exactly 102 patients presenting to the emergency room of the Hospital Servidor Publico Estadual in Sao Paulo,Brazil,participated in this before-and-after *** participants had musculoskeletal pain and were treated with the technique proposed by Marques *** emergency acupuncture involved inserting a needle at a point defined by traditional Chinese medicine and applying intense stimulation for 10 s;no more than two points were used on any individual *** was measured using a numerical visual scale before and immediately after the ***:Participants in this study were mostly women(78%),had a college degree(47%)and were below the age of 60(56%).The most common region of pain was the lower back(31%),and the most common type of pain was acute and exacerbated chronic *** meridians most commonly involved were the eight extra meridians(40%),and the points most often used for treatment were Houxi(SI3),Shenmai(BL62)and Zulinqi(GB41).Almost all participants reported a decrease in pain intensity,independent of sex,education level,pain site and pain type(acute/chronic;P<0.05).At the end of the session,only4%of the participants reported a desire for allopathic ***:This emergency acupuncture technique for analgesia appears to reduce musculoskeletal *** registration:Brazilian Registry of Clinical Trials(http://***/)with ***-8 dmfjf.

关键词： Acupuncture analgesia Emergency medical services Acute pain Acupuncture therapy

Spectroscopy of a Gamma Irradiated Poly(Acrylic Acid)-Clotrimazole System

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2011年第12期28卷 274-277页

作者： M.Todica C.V.Pop luciana Udrescu Traian Stefan Faculty of Physics Babes-Bolyai University400084 Cluj-NapocaRomania

A poly(acrylic acid)-clotrimazole system,gamma irradiated at different doses,is investigated by Raman *** of the spectrum of the polymeric matrix appear for doses of radiation greater than 333 Gy,whereas the spectrum of clotrimazole remains unaffected at these doses of *** changes correlate with modification of the vibration modes of COOH and CH_(2) groups of a polymeric matrix after irradiation.

关键词： spectroscopy polymeric matrix

Living-donor liver transplantation in Budd-Chiari syndrome with inferior vena cava complete thrombosis:A case report and review of the literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2021年第1期13卷 151-161页

作者： Vinicius Rocha-Santos Daniel Reis Waisberg Rafael Soares Pinheiro Lucas Souto Nacif Rubens Macedo arantes Liliana Ducatti Rodrigo Bronze Martino luciana Bertocco Haddad Flavio Henrique Galvao Wellington Andraus Luiz Augusto Carneiro-D'Alburquerque Department of Gastroenterology Abdominal Organs Transplantation DivisionHospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo(HC-FMUSP)Sao Paulo 05403900SPBrazil Department of Gastroenterology Laboratory of Medical Investigation 37(LIM-37)Faculdade de Medicina da Universidade de Sao Paulo(FMUSP)Sao Paulo 01246903Brazil

BACKGROUND Budd-Chiari syndrome(BCS)is a challenging indication for liver transplantation(LT)due to a combination of massive liver,increased bleeding,retroperitoneal fibrosis and frequently presents with stenosis of the inferior vena cava(IVC).Occasionally,it may be totally thrombosed,increasing the complexity of the procedure,as it should also be *** challenge is even greater when performing living-donor LT as the graft does not contain the retrohepatic IVC;thus,it may be necessary to reconstruct *** SUMMARY A 35-year-old male patient with liver cirrhosis due to BCS and hepatocellular carcinoma beyond the Milan criteria underwent living-donor LT with IVC *** was necessary to remove the IVC as its retrohepatic portion was completely thrombosed,up to almost the right atrium.A right-lobe graft was retrieved from his sister,with outflow reconstruction including the right hepatic vein and the branches of segment V and VIII to the middle hepatic *** to massive subcutaneous collaterals in the abdominal wall,venovenous bypass was implemented before incising the *** right atrium was reached via a transdiaphragramatic *** was performed en bloc with the retrohepatic vena *** was reconstructed with an infra-hepatic vena cava graft obtained from a deceased *** patient remains well on outpatient clinic follow-up 25 mo after the procedure,under an anticoagulation protocol with *** Living-donor LT in BCS with IVC thrombosis is feasible using a meticulous surgical technique and tailored strategies.

关键词： Liver transplantation Living donors Budd-Chiari syndrome Hepatic venoocclusive disease Inferior vena cava Case report

Highly Dynamic Polynuclear Metal Cluster Revealed in a Single Metallothionein Molecule

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2021年第1期2021卷 620-630页

作者： Guodong Yuan Felipe Curtolo Yibing Deng Tao Wu Fang Tian Qun Ma Yutong Liu Jinglin Zuo Guilherme Menegon arantes Peng Zheng State Key Laboratory of Coordination Chemistry Chemistry and Biomedicine Innovation Center(ChemBIC)School of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu 210023China Department of Biochemistry Instituto de QuímicaUniversidade de São PauloAv.Prof.Lineu Prestes 74805508-900 São PauloSPBrazil

Human metallothionein(MT)is a small-size yet efficient metal-binding protein,playing an essential role in metal homeostasis and heavy metal *** contains two domains,each forming a polynuclear metal cluster with an exquisite hexatomic ring *** apoprotein is intrinsically disordered,which may strongly influence the clusters and the metal-thiolate(M-S)bonds,leading to a highly dynamic ***,these features are challenging to identify due to the transient nature of these *** individual signal from dynamic conformations with different states of the cluster and M-S bond will be averaged and blurred in classic ensemble *** circumvent these problems,we combined a single-molecule approach and multiscale molecular simulations to investigate the rupture mechanism and chemical stability of the metal cluster by a single MT molecule,focusing on the Zn4S11 cluster in theαdomain upon *** multiple unfolding pathways and intermediates are observed for both domains,corresponding to different combinations of M-S bond *** of the pathways is clearly preferred suggesting that unfolding proceeds from the distribution of protein conformational substates with similar M-S bond *** indicate that the metal cluster may rearrange,forming and breaking metal-thiolate bonds even when MT is folded independently of large protein backbone ***,a highly dynamic polynuclear metal cluster with multiple conformational states is revealed in MT,responsible for the binding promiscuity and diverse cellular functions of this metal-carrier protein.

关键词： structure cluster bonds