Inflammatory bowel disease in pediatric and adolescent patients:A biomolecular and histopathological review
Inflammatory bowel disease in pediatric and adolescent patients:A biomolecular and histopathological review作者机构:Department of PediatricsUniversity of MessinaI-98125 MessinaItaly Department of Human PathologyUniversity of MessinaI-98125 MessinaItaly
出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))
年 卷 期:2014年第20卷第30期
页 面:10262-10278页
核心收录:
学科分类:1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
主 题:Pediatric inflammatory bowel disease Crohn's disease Ulcerative disease Histopathology Molecular biology
摘 要:Crohn’s disease (CD) and ulcerative colitis (UC) are the two main forms of inflammatory bowel disease (IBD) with both overlapping and distinct clinical, pathological and biomolecular features. It has been suggested that pediatric IBD is a distinct disease entity, with probably different disease *** aim of this study is to review and summarize the evolution of the current concept of pediatric IBD. The results of this review reinforce the idea that pediatric CD and UC may be further classified in various clinicopathologic entities. For clinicians and pathologists convenience, practical algorithms for the distinction of the various subphenotypes of pediatric IBD are also provided.