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Microstructure of TiB Whisker Reinforced Ti Matrix Composite

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Journal of Materials Science & Technology 1997年第1期13卷 41-44页

作者： lu, yx Li, DX Ping, DH Bi, J Ma, ZY Institute of Metal Research Chinese Academy of Sciences Shenyang 110015 China

The composite of Ti matrix with TiB whisker reinforcement has been successfully fabricated. The content of TiB whisker in Ti matrix can reach about 30 vol. pet. Metallographic examination, morphology and microstructure of TiB whisker, interface structure between TiB whisker and Ti matrix were investigated using optical microscope, SEM, TEM and HREM technology. The diameter distribution of TiB whisker is from 0.1 mu m to 3.5 mu m and the aspect ratio of TiB whisker is from 10 to 20. The cross-section of whisker is generally polygon. Because of good compatibility between TiB whisker and Ti matrix it is identified that there is no obvious interaction of Ti matrix with TiB reinforcement and TiB whisker reinforced Ti matrix composites have excellent elevated properties.

关键词： Fiber reinforced materials

Effects of Solution Temperature on Tensile Properties ofSiC_w/2024Al Composite

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Journal of Materials Science & Technology 1995年第4期11卷 291-294页

作者： MA, ZY lu, yx luO, M BI, J ZHANG, YZ NE UNIV TECHNOL SHENYANG 110006PEOPLES R CHINA

The effects of solution (quench) temperature on the properties of SiCW/Al composite have been investigated using tensile tests. The experiments indicate that the solution temperature of the composite fabricated by P/M technique can be raised to 560 degrees C. The tensile strength of the composite is obviously dependent on solution (quench) temperature and the composite solutionized at 540 degrees C exhibits a maximum of tensile strength and elongation-to-failure. These results can be accounted for by the variation of the dislocation density in the composite.

关键词： Metallic matrix composites

逆转录病毒载体介导人胰岛素样生长因子Ⅰ在大鼠成肌细胞中的表达及分泌

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中国组织工程研究与临床康复 2007年第37期11卷 7409-7412页

作者：米少华卢永昕荣书玲华中科技大学附属协和医院心内科湖北省武汉市430022

目的:将经逆转录病毒载体的介导的人胰岛素样生长因子Ⅰ基因导入大鼠成肌细胞,观察其是否表达,为组织工程人工肌肉体内基因治疗打下基础。方法:实验于2005-10/2006-12在华中科技大学同济医学院协和医院心血管病研究所完成。①实验材料:P... 详细信息

目的:将经逆转录病毒载体的介导的人胰岛素样生长因子Ⅰ基因导入大鼠成肌细胞,观察其是否表达,为组织工程人工肌肉体内基因治疗打下基础。方法:实验于2005-10/2006-12在华中科技大学同济医学院协和医院心血管病研究所完成。①实验材料:PLghIGF1SN由本实验室保存,逆转录病毒包装细胞系GP+E86购自Clontech公司,包装细胞PT67购自ATCC。②实验方法:选用新生SD乳鼠骨骼肌进行成肌细胞的原代培养,选用新生SD乳鼠心脏进行心肌细胞的培养。通过脂质体2000将人胰岛素样生长因子ⅠcDNA导入逆转录病毒包装细胞PT67,经过G418筛选获取稳定表达病毒的克隆,NIH3T3细胞测定病毒滴度,挑取滴度高的克隆扩增,收取高滴度的病毒上清液,转染成肌细胞。③实验评估:G418筛选转染过的成肌细胞,采用ELISA方法检测其上清液中人胰岛素样生长因子Ⅰ的表达,采用MTT法检测人胰岛素样生长因子Ⅰ的生物学活性。结果:①病毒滴度的测定:利用不同量的病毒上清感染1×105NIH3T3细胞,并经G418筛选,测得不同PT67克隆的培养上清中,病毒滴度最高为8×105cfu/mL。②ELISA方法检测人胰岛素样生长因子Ⅰ的表达:在转染后大鼠成肌细胞分泌的上清液中可以检测到人胰岛素样生长因子Ⅰ的表达,经过G418筛选2周后,收集培养液,人胰岛素样生长因子Ⅰ浓度最高在40μg/L,总量可以达到(150～200)ng/2×106/d。未转染成肌细胞组人胰岛素样生长因子Ⅰ浓度约在0.3μg/L。③MTT法检测人胰岛素样生长因子Ⅰ的生物学活性:转染的成肌细胞培养上清液刺激心肌细胞后,心肌细胞活力明显增加。结论:人胰岛素样生长因子Ⅰ基因可在鼠成肌细胞内稳定表达并具有生物学效应,可用于心血管系统基因治疗的研究。

关键词： hIGF-Ⅰ 逆转录病毒成肌细胞

ISOLATION AND STRUCTURE OF RANAMARGARIN,A NEW TACHYKININ FROM THE SKIN OF CHINESE FROG Rana margaratae

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Science China Chemistry 1989年第5期32卷 570-579页

作者：唐易全田盛海吴时祥华家柽吴贯夫赵尔宓陆一安朱应麒邹冈 Shanghai Institute of Materia Medica Academia Sinica Chengdu Institute of Biology Academia Sinica Shanghai Centre of Biotechnology Academia Sinica

A new tetradecapeptide, ranamargarin, has been isolated by Sep-Pak C_(18) and HPLC from methanol extracts of the skin of the Chinese frogRana margaratae. The sequence of the peptide is: Asp-Asp-Ala-Ser-Asp-Arg-Ala-Lys-Lys-Phe-Tyr-Gly-Leu-Met-NH_2. This structure has been confirmed by synthesis. The peptide is the largest among the amphibian tachykinins and its N-terminal amino acids are quite different from those of the other tachykinins. The formation of the sulfoxide and peak-splitting of ranamargarin during purification procedures are briefly discussed.

关键词： ranamargarin Rana margaratae amphibian skin HPLC sequence analysis.

Th1型细胞因子干扰素γ及Th2型细胞因子白细胞介素10水平在慢性心力衰竭患者接受己酮可可碱干预过程中的变化:随机对照

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中国组织工程研究与临床康复 2007年第45期11卷 9079-9082页

作者：万建平卢永昕徐玉兰刘向阳华中科技大学同济医学院附属协和医院心血管病研究所湖北省武汉市430022 韶关市粤北医院心内科广东省韶关市512000

目的:观察己酮可可碱治疗心力衰竭患者后Th1型细胞因子干扰素γ及Th2型细胞因子白细胞介素10水平的变化,评价己酮可可碱对慢性心力衰竭患者免疫异常调节作用。方法:选择2005-09/2006-04华中科技大学同济医学院附属协和医院心内科收治的... 详细信息

目的:观察己酮可可碱治疗心力衰竭患者后Th1型细胞因子干扰素γ及Th2型细胞因子白细胞介素10水平的变化,评价己酮可可碱对慢性心力衰竭患者免疫异常调节作用。方法:选择2005-09/2006-04华中科技大学同济医学院附属协和医院心内科收治的心力衰竭患者38例。①实验分组:随机分为常规治疗组20例,常规治疗包括利尿剂,洋地黄类药物,血管紧张素转换酶抑制剂,β-受体阻滞剂等。己酮可可碱治疗组18例,在常规治疗的基础上加用己酮可可碱400mg,3次/d,饭时口服。两组治疗时间为1周,且均禁用免疫抑制剂。另选取10例健康体检者作为健康对照组。②实验评估:采用流式细胞分析法对各组患者进行CD4+Th1型细胞因子干扰素γ和Th2型细胞因子白细胞介素10水平进行检测,从而测出相应Th1,Th2细胞的百分比。结果:参与常规治疗组实验患者均进入结果分析,参与己酮可可碱治疗组患者18例,脱落3例,余15例患者均进入结果分析。①慢性心力衰竭患者CD4+干扰素γ表达水平和Th1/Th2值高于健康对照组(P<0.05),CD4+白细胞介素10表达水平低于健康对照组(P<0.05)。②己酮可可碱治疗组治疗1周后,CD4+干扰素γ水平和Th1/Th2值低于常规治疗组(P<0.05)。CD4+白细胞介素10水平无显著性变化。结论:心力衰竭患者存在Th1/Th2失衡,己酮可可碱调节了慢性心力衰竭患者Th1/Th2的失衡,该效应可能是己酮可可碱改善慢性心力衰竭患者症状作用机制之一。

关键词：心力衰竭己酮可可碱 Th细胞广谱免疫凋节

An embedded electron current layer observed at the edge of the plasma sheet in the Earth’s magnetotail

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Earth and Planetary Physics 2025年第1期9卷 148-158页

作者： ChenChen Zhan RongSheng Wang QuanMing lu San lu XinMin Li Deep Space Exploration Laboratory/School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China Chinese Academy of Sciences(CAS)Center for Excellence in Comparative Planetology/CAS Key Laboratory of Geospace Environment/Anhui Mengcheng National Geophysical Observatory University of Science and Technology of ChinaHefei 230026China Collaborative Innovation Center of Astronautical Science and Technology Harbin 150001China

The formation of an embedded electron current sheet within the magnetotail plasma sheet has been poorly *** this article,we present an electron current layer detected at the edge of the magnetotail plasma *** ions were demagnetized inside the electron current layer,but the electrons were still frozen in with the magnetic field ***,this decoupling of ions and electrons gave rise to a strong Hall electric field,which could be the reason for the formation of the embedded thin current *** magnetized electrons,the absence of the nongyrotropic electron distribution,and negligible energy dissipation in the layer indicate that magnetic reconnection had not been triggered within the embedded thin current *** highly asymmetric plasma on the two sides of the current layer and low magnetic shear across it could suppress magnetic *** observations indicate that the embedded electric current layer,probably generated by the Hall electric field,even down to electron scale,is not a sufficient condition for magnetic reconnection.

关键词： magnetotail plasma sheet magnetic reconnection

Understanding the local structure and thermophysical behavior of Mg-La liquid alloys via machine learning potential

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 439-449页

作者： Jia Zhao Taixi Feng Guimin lu National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China Joint International Laboratory for Potassium and Lithium Strategic Resources East China University of Science and TechnologyShanghai 200237China

The local structure and thermophysical behavior of Mg-La liquid alloys were in-depth understood using deep potential molecular dynamic(DPMD) simulation driven via machine learning to promote the development of Mg-La alloys. The robustness of the trained deep potential(DP) model was thoroughly evaluated through several aspects, including root-mean-square errors(RMSEs), energy and force data, and structural information comparison results;the results indicate the carefully trained DP model is reliable. The component and temperature dependence of the local structure in the Mg-La liquid alloy was analyzed. The effect of Mg content in the system on the first coordination shell of the atomic pairs is the same as that of temperature. The pre-peak demonstrated in the structure factor indicates the presence of a medium-range ordered structure in the Mg-La liquid alloy, which is particularly pronounced in the 80at% Mg system and disappears at elevated temperatures. The density, self-diffusion coefficient, and shear viscosity for the Mg-La liquid alloy were predicted via DPMD simulation, the evolution patterns with Mg content and temperature were subsequently discussed, and a database was established accordingly. Finally, the mixing enthalpy and elemental activity of the Mg-La liquid alloy at 1200 K were reliably evaluated,which provides new guidance for related studies.

关键词： magnesium-lanthanum liquid alloys local structure macroscopic properties thermodynamic behavior deep potential mo-lecular dynamic simulation

Dynamical complexity of Anosov systems driven by a quasi-periodic force

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Science China Mathematics 2025年第1期 89-136页

作者： Wen Huang Zeng Lian Kening lu Department of Mathematics University of Science and Technology of China School of Mathematics Sichuan University

Consider C2Anosov systems on a compact manifold driven by a quasi-periodic *** study their dynamical complexity on various levels from the perspectives of both path-wise dynamics and stochastic *** that these systems are non-wandering（i.e.,every point in the phase space is nonwandering）,we prove a set of results:（1） the existence of abundance of random periodic points;（2） a random Liv?ic theorem;（3） a random Ma?é-Bousch-Conze-Guivarc'h lemma;（4） the existence of strong random ***,a concrete example constructed on a 2-dimensional torus is also given to uncover some interesting phenomena of the systems.

关键词：

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Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng Jie Shen Jinxing lu Chuqiang Huang Zhuoyuan Chen Feng Peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Glycerol electrooxidation Hydrogen evolution Ru doping Cobalt phosphide Bifunctional electrocatalysts