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Algebra Colloquium 2021年第1期28卷 87-90页

作者： Oscar Guajardo garza Marina Rasskazova Liudmila Sabinina Centro de Investigacion en Ciencias UAEMCuernavacaMexico Omsk State Technical University pr.Mira 11OmskRussia

We study the variety of binary Lie algebras defined by the identities x^(2)=J(x,y,zu)=0,where J(a,b,c)denotes the Jacobian of a,b,*** on previous work by Carrillo,Rasskazova,Sabinina and Grishkov,in the present articl... 详细信息

关键词： Malcev theorem Levi factor splitting algebra binary Lie algebra

Intragastric injection of botulinum toxin for the treatment of obesity. Where are we?

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World Journal of Gastroenterology 2008年第12期14卷 1805-1809页

作者： Diego Garcia-Compean Hector Maldonado garza Department of Gastroenterology Faculty of Medicine University Hospital. Ave Madero y Gonzalitos Col Mitras Centro Monterrey 64700 Mexico

Obesity has reached epidemic proportions particularly in western countries. Most non-surgical treatments of this condition are disappointing. Since 2005, several studies evaluating the effect of Botulinum Toxin type A (BT-A) in gastric antrum by means of endoscopy for the treatment of obesity have been published. This treatment modality was based on the observation that gastric injection of BT-A in laparatomized rats induced a significant reduction of food intake and body weight. Nowadays, 6 studies have been published yielding conflicting results. Differences in selection of patients, doses of BT-A, method of administration of the toxin and instruments of evaluation of some parameters among these studies may be the cause of divergent results. We discuss herein some important features of these studies pointing out on differences among them. At the same time, based on the knowledge of physiological characteristics of normal and abnormal gastric function related with feeding, we discuss the probable causes of failure observed in these trials. Finally, we give some guidelines concerning the way that future research in this field may follow, not without calling attention to disadvantages of this treatment.

关键词： Botulinum toxin Obesity Gastric emptying Gastric motility Gastroparesis

Predefined-Time Backstepping Stabilization of Autonomous Nonlinear Systems

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IEEE/CAA Journal of Automatica Sinica 2022年第11期9卷 2020-2022页

作者： Alison garza-Alonso Michael Basin Pablo Cesar Rodriguez-Ramirez the School of Physical and Mathematical Sciences Autonomous University of Nuevo LeonSan Nicolas de los GarzaNuevo Leon 66455Mexico Ningbo Institute of Intelligent Equipment Technology Zhejiang 315032China

Dear Editor,In this letter,the backstepping technique is applied to solve the predefined-time stabilization problem for autonomous nonlinear systems,where nonlinear terms are unknown but satisfy a linear growth condition.A linear time-varying control law is designed to drive all states of an autonomous nonlinear system to the origin for an a priori preassigned time.

关键词： nonlinear autonomous satisfy

A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication

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World Journal of Gastroenterology 2014年第6期20卷 1438-1449页

作者： Elvira garza-González Guillermo Ignacio Perez-Perez Héctor Jesús Maldonado-garza Francisco Javier Bosques-Padilla Servicio de Gastroenterología y Departamento de Patología Clínica Hospital Universitario "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León Departments of Medicine and Microbiology New York University School of Medicine

Helicobacter pylori (H. pylori) affects nearly half of the world’s population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic methods exist to detect infection, and the choice of one method or another depends on several factors, such as accessibility, advantages and disadvantages of each method, cost, and the age of patients. Once H. pylori infection is diagnosed, the clinician decides whether treatment is necessity, according to the patient’s clinical condition. Typically, eradication of H. pylori is recommended for treatment and prevention of the infection. Cure rates with the standard triple therapy are acceptable, and effective quadruple therapies, sequential therapies, and concomitant therapies have been introduced as key alternatives to treat H. pylori infection. In this work, we review the main diagnostic methods used to identify H. pylori infection and to confirm eradication of infection. In addition, key factors related to treatment are reviewed.

关键词： Diagnosis Helicobacter pylori Treatment Hybrid therapy Concomitant therapy Sequential therapy

Vascularization in interconnected 3D printed Ti-6Al-4V foams with hydrogel matrix for biomedical bone replacement implants

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Science China Materials 2018年第4期61卷 565-578页

作者： Victor L.Correa Kristine M.garza Lawrence E.Murr Department of Metallurgical Materials and Biomedical Engineering University of Texas at El Paso Department of Biological Sciences University of Texas at El Paso

Vascularization on newly implanted metal orthopedic implants has remained a challenge in the field of tissue engineering. To address this challenge, in this research,an interconnected foam structure of Ti-6 Al-4 V was microfabricated by electron beam melting(EBM) technique. The foam in question has a density of 1.77 g cm-3 with 60% porosity and a tensile strength of 18 GPa. An extracellular matrix based hydrogel was added as an aqueous matrix to the *** mimetic stress has been closely related to many wound healing biomedical applications as it increases survival and proliferation molecular signals. To that end, increased expression of hypoxia-inducible factor-1α(Hif-1α) and vascular endothelial growth factor(VEGF) in the aqueous hydrogel matrix was achieved by the addition of a hypoxia mimetic deferoxamine mesylate(DFM). In this study, the formation of an endothelial network was achieved in a hydrogel matrix in the presence of the before mentioned 3 D printed metal foam. Cellular viability, fluorescent microscopy and scanning electron microscopy imaging analysis demonstrate that pre-osteoblasts undergo proliferation and also attach efficiently to the foam when exposed to DFM. Human umbilical vascular endothelial cells(HUVECs) were grown in an extracellular matrix-like 3 D hydrogel and a hypoxia-like stress was achieved. This research demonstrates that pre-osteoblast cells undergo cell differentiation and increase the production of hydroxyapatite on exposure to the hypoxia mimetic molecule. This proposed approach encompasses an ideal prototype for a completely living implanted structure for future orthopedic implants.

关键词： Ti-6Al-4V electron beam melting angiogenesis deferoxamine mesylate hydrogel vascularization

Comparative Analysis of Different Evaluation Functions for Protein Structure Prediction Under the HP Model

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Journal of Computer Science & Technology 2013年第5期28卷 868-889页

作者： Mario garza-Fabre Eduardo Rodriguez-Tello Gregorio Toscano-Pulido Information Technology Laboratory CINVESTAV-Tamaulipas Km.5.5 Carretera Ciudad Victoria-Soto La Marina 87130 Ciudad Victoria Tamaulipas México

The HP model for protein structure prediction abstracts the fact that hydrophobicity is a dominant force in the protein folding process. This challenging combinatorial optimization problem has been widely addressed through metaheuristics. The evaluation function is a key component for the success of metaheuristics; the poor discrimination of the conventional evaluation function of the HP model has motivated the proposal of alternative formulations for this component. This comparative analysis inquires into the effectiveness of seven different evaluation functions for the HP model. The degree of discrimination provided by each of the studied functions, their capability to preserve a rank ordering among potential solutions which is consistent with the original objective of the HP model, as well as their effect on the performance of local search methods are analyzed. The obtained results indicate that studying alternative evaluation schemes for the HP model represents a highly valuable direction which merits more attention.

关键词： evaluation function protein structure prediction metaheuristics combinatorial optimization bioinformatics

Letter to the Editor concerning:Gallbladder perforation:A single-center experience in north India and a step-up approach for management

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Hepatobiliary & Pancreatic Diseases International 2022年第6期21卷 617-618页

作者： Hermilo Jeptef Angeles-Mar Mariano Garcia-Camp RodrigoEnrique Elizondo-Omaña Santos Guzmán-López Javier Humberto Martinez-garza Alejandro Quiroga-garza Universidad Autonoma de Nuevo Leon School of MedicineHuman Anatomy DepartmentMonterreyNuevo León CP 64460México Universidad Autonoma de Nuevo Leon School of MedicinePlataforma INVEST-KER Unito Mayo Clinic(KER Unit Mexico)MonterreyNuevo LeónMéxico General Surgery Division Instituto Mexicano del Seguro SocialMonterreyNuevo LeónMéxico

To the Editor:We sincerely applaud the work done by Gupta et al.,in which they analyzed a single-center experience regarding gallbladder per-foration(GBP)management[1].Currently,there is a lack of cohort studies to adequately describe the approach strategies and man-agement for this pathology,with international guidelines making ambiguous recommendations[2,3].Their study stratified GBP types and provided details regarding clinical presentation,comorbidities,preoperative diagnosis,etiology,imaging techniques,and surgical *** study reported a high conversion rate when a la-paroscopic approach was attempted for cholecystectomy.

关键词： diagnosis concerning approach

Current knowledge on the laboratory diagnosis of Clostridium difficile infection

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World Journal of Gastroenterology 2017年第9期23卷 1552-1567页

作者： Adrián Martínez-Meléndez Adrián Camacho-Ortiz Rayo Morfin-Otero Héctor Jesús Maldonado-garza Licet Villarreal-Trevino Elvira garza-González Departamento de Microbiología e Inmunología Facultad de Ciencias BiológicasUniversidad Autónoma de Nuevo León.Pedro de Alba S/NCiudad UniversitariaSan Nicolás de los Garza Servicio de Infectología Hospital Universitario“Dr.JoséEleuterio González”Universidad Autónoma de Nuevo León.Av.Francisco I.Madero Pte.S/NCol.Mitras Centro.Monterrey Hospital Civil de Guadalajara “Fray Antonio Alcalde”e Instituto de Patología Infecciosa y ExperimentalCentro Universitario de Ciencias de la SaludUniversidadde Guadalajara.Sierra Mojada 950Col.Independencia Servicio de Gastroenterología Hospital Universitario“Dr.JoséEleuterio González”Universidad Autónoma de Nuevo León.Av.Francisco I.Madero Pte.S/NCol.Mitras Centro.Monterrey

Clostridium difficile (C. difficile) is a spore-forming, toxin-producing, gram-positive anaerobic bacterium that is the principal etiologic agent of antibiotic-associated diarrhea. Infection with C. difficile (CDI) is characterized by diarrhea in clinical syndromes that vary from selflimited to mild or severe. Since its initial recognition as the causative agent of pseudomembranous colitis, C. difficile has spread around the world. CDI is one of the most common healthcare-associated infections and a significant cause of morbidity and mortality among older adult hospitalized patients. Due to extensive antibiotic usage, the number of CDIs has increased. Diagnosis of CDI is often difficult and has a substantial impact on the management of patients with the disease, mainly with regards to antibiotic management. The diagnosis of CDI is primarily based on the clinical signs and symptoms and is only confirmed by laboratory testing. Despite the high burden of CDI and the increasing interest in the disease, episodes of CDI are often misdiagnosed. The reasons for misdiagnosis are the lack of clinical suspicion or the use of inappropriate tests. The proper diagnosis of CDI reduces transmission, prevents inadequate or unnecessary treatments, and assures best antibiotic treatment. We review the options for the laboratory diagnosis of CDI within the settings of the most accepted guidelines for CDI diagnosis, treatment, and prevention of CDI.

关键词： Clostridium difficile Toxigenic culture Nucleic acid amplification tests Enzyme immunoassay Diagnosis Glutamate dehydrogenase

Liver cirrhosis and diabetes:Risk factors,pathophysiology,clinical implications and management

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World Journal of Gastroenterology 2009年第3期15卷 280-288页

作者： Diego Garcia-Compean Joel Omar Jaquez-Quintana Jose Alberto Gonzalez-Gonzalez Hector Maldonado-garza Department of Gastroenterology Faculty of MedicineUniversity HospitalAve Madero y GonzalitosCol Mitras CentroMonterrey 64700Mexico

About 30% of patients with cirrhosis have diabetes mellitus(DM).Nowadays,it is a matter for debate whether type 2 DM in the absence of obesity and hypertriglyceridemia may be a risk factor for chronic liver ***,which develops as a complication of cirrhosis,is known as "hepatogenous diabetes".Insulin resistance in muscular and adipose tissues and hyperinsulinemia seem to be the pathophysiologic bases of diabetes in liver *** impaired response of the islet β-cells of the pancreas and hepatic insulin resistance are also contributory ***-alcoholic fatty liver disease,alcoholic cirrhosis,chronic hepatitis C(CHC) and hemochromatosis are more frequently associated with *** resistance increases the failure of the response to treatment in patients with CHC and enhances progression of *** in cirrhotic patients may be *** diabetes is clinically different from that of type 2 DM,since it is less frequently associated with microangiopathy and patients more frequently suffer complications of *** increases the mortality of cirrhotic *** of the diabetes is complex due to liver damage and hepatotoxicity of oral hypoglycemic *** manuscript will review evidence that exists in relation to:type 2 DM alone or as part of the metabolic syndrome in the development of liver disease;factors involved in the genesis of hepatogenous diabetes;the impact of DM on the clinical outcome of liver disease;the management of DM in cirrhotic patients and the role of DM as a risk factor for the occurrence and exacerbation of hepatocellular carcinoma.

关键词： Insulin resistance Type 2 diabetes mellitus Liver cirrhosis Hepatocellular carcinoma Chronic hepatitis C