检索结果-南通市图书馆

Compositions and Pressure-Temperature Conditions of Metamorphic Fluids Overprinting the Talate VMS Pb-Zn Deposit,Southern Altay,China

引用

Acta Geologica Sinica(English Edition) 2015年第3期89卷 794-810页

作者： ZHANG Hui XU Jiuhua CHENG Xihui guo Xuji LIN longhua YANG Rui BIAN Chunjing Resource Engineering Department University of Science and Technology Beijing No.706 Geological Party Xinjiang Geoexploration Bureau for Nonferrous Metals

The Talate Pb-Zn deposit,located in the east of the NW-SE extending Devonian Kelan volcanic-sedimentary basin of the southern Altaides,occurs in the metamorphic rock series of the upper second lithological section of the lower Devonian lower Kangbutiebao Formation（D_1k_1~2）.The Pb-Zn orebodies are stratiform and overprinted by late sulfide—quartz *** distinct mineralization periods were identified：a submarine volcanic sedimentary exhalation period and a metamorphic hydrothermal mineralization *** metamorphic overprinting period can be further divided into two stages：an early stage characterized by bedding-parallel lentoid quartz veins developed in the chlorite schist and leptite of the ore-bearing horizon,and a late stage represented by pyritechalcopyrite-quartz veins crosscutting chlorite schist and leptite or the massive Pb-Zn *** inclusions in the early metamorphic quartz veins are mainly CO_2-H_2O-NaCI and carbonic（CO_2±CH_4±N_2） inclusions with minor aqueous *** CO_2-H_2O-NaCl inclusions have homogenization temperatures of 294-368℃,T_（m,CO2） of-62.6 to-60.5℃,T_（h,CO2） of 7.7 to 29.6℃（homogenized into liquid）,and salinities of 5.5-7.4 wt%NaCl *** carbonic inclusions have T_（m,CO2）of-60.1 to-58.5℃,and T_（h,Co2） of-4.2 to 20.6℃.Fluid inclusions in late sulfide quartz veins are also dominated by CO_2-H_2O-NaCl and CO_2±CH_4 *** CO_2-H_2O-NaCl inclusions have T_（b,tot） of142 to 360℃,T_（m,CO2）of-66.0 to-56.6℃,T_（h,CO2） of-6.0 to 29.4℃（homogenized into liquid） and salinities of 2.4-16.5 wt%NaCl *** carbonic inclusions have T_（m,Co2）of-61.5 to-57.3℃,and T_（h,CO2） of-27.0to 28.7℃.The aqueous inclusions（L-V） have T_（m,ice） of-9.8 to-1.3℃ and T_（h,tot） of 205 to 412℃.The P-T trapping conditions of CO_2-rich fluid inclusions（100-370 MPa,250-368℃） are comparable with the late- to post-regional metamorphism *** CO_2-rich fluids,possibly derived from regional metamorphism,were involved in the reworking and metal enr

关键词： Fluid inclusion Talate Pb-Zn deposit Metamorphism Altay

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Host cyclophilin A facilitates SARS-CoV-2 infection by binding and stabilizing spike on virions

引用

Signal Transduction and Targeted Therapy 2024年第1期9卷 36-39页

作者： Xiangpeng Sheng Fang Zhu Hong Peng Fan Yang Yi Yang Cong Yang Zhen Wang Wei Chen Deyin guo Ronggui Hu State Key Laboratory of Molecular Biology Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghaiChina MOE Key Laboratory of Tropical Disease Control Centre for Infection and Immunity StudySchool of MedicineSun Yat-sen UniversityShenzhenChina ICU Longhua Hospital Shanghai University of Traditional Chinese MedicineShanghaiChina

Dear Editor,The novel coronavirus SARS-CoV-2 rapidly evolutes to increase its infectivity and transmissibility,facilitates its immune escape,impairs vaccine efficacy,and currently causes repeated infections in human,which is mainly determined by the accumulated mutations in spike(S).1 Transmembrane S is a heavily glycosylated protein on the surface of the virion as homotrimer,responsible for binding to human angiotensin-converting enzyme 2(hACE2)receptor.2 While the architecture of S trimers has been well studied,how the stability of S is regulated by potential host factors remains unknown.

关键词： ACE2 vaccine infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genome-Wide Identification of Candidate Genes Associated with β-glucan Traits in a Hulled and Hulless Barley (Hordeum vulgare L.) Population

引用

Phyton-International Journal of Experimental Botany 2020年第4期89卷 987-997页

作者： longhua Zhou Ting He Guimei guo Jing Li Ruiju Lu Yingbo Li Chenghong Liu Shanghai Academy of Agricultural Sciences Shanghai201106China Shanghai Key Laboratory of Agricultural Genetics and Breeding Shanghai201106China

Barley grain is a valuable source ofβ-glucan,which is an important component of dietary fiber with significant human health *** the genetic basis ofβ-glucan biosynthesis has been widely studied,a genome-wide association study(GWAS)is still required for a scan of the candidate genes related to the complex quantitative trait based on the high-quality barley reference *** this study,a GWAS was conducted using a population composed of 87 barley landraces(39 hulled and 48 hulless,β-glucan from 2.07%to 6.56%)with 191,098 nucleotide polymorphisms(SNPs)markers to cover the chromosomes with the highest *** population was divided into four sub-populations(POP1~POP4),and theβ-glucan content in POP2 was significantly higher than that in other groups,in which most of the hulless barley landraces are from Qinghai-Tibet Plateau in *** seven SNP markers identified by GWAS,two(SNP2 and SNP3)of them showed positive correlation toβ-glucan trait and the remaining five(SNP1,SNP4,SNP5,SNP6 and SNP7)showed the negative *** candidate genes linked to SNP7,HORVU7Hr1G000320 and HORVU7Hr1G000040,belong to the nucleotide triphosphate hydrolase super-family which is probable to affect the activities ofβ-glucan *** candidate gene associated with SNP1,HORVU1Hr1G000010,is possibly involved in sugar *** conclusion,our results provide new insights into the genetic basis ofβ-glucan accumulation in barley grains,and the discovery of new SNP markers distributed in each chromosome and the associated candidate genes will be valuable for the breeding of functional barley varieties with high β-glucan.

关键词： GWAS β-glucan SNP barley grains

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pathological progression of osteoarthritis:a perspective on subchondral bone

引用

Frontiers of Medicine 2024年第2期18卷 237-257页

作者： Xuefei Li Wenhua Chen Dan Liu Pinghua Chen Shiyun Wang Fangfang Li Qian Chen Shunyi Lv Fangyu Li Chen Chen Suxia guo Weina Yuan Pan Li Zhijun Hu longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai200032China Research and Development Center of Chinese Medicine Resources and Biotechnology Shanghai University of Traditional Chinese MedicineShanghai201203China

Osteoarthritis(OA)is a degenerative bone disease associated with *** rising global aging population has led to a surge in OA cases,thereby imposing a significant socioeconomic *** have been keenly investigating the mechanisms underlying *** studies have suggested that the disease starts with synovial inflammation and hyperplasia,advancing toward cartilage ***,subchondral-bone collapse,sclerosis,and osteophyte formation *** progression is deemed as“top to bottom.”However,recent research is challenging this perspective by indicating that initial changes occur in subchondral bone,precipitating cartilage *** this review,we elucidate the epidemiology of OA and present an in-depth overview of the subchondral bone’s physiological state,functions,and the varied pathological shifts during OA *** also introduce the role of multifunctional signal pathways(including osteoprotegerin(OPG)/receptor activator of nuclear factor-kappa B ligand(RANKL)/receptor activator of nuclear factor-kappa B(RANK),and chemokine(CXC motif)ligand 12(CXCL12)/CXC motif chemokine receptor 4(CXCR4))in the pathology of subchondral bone and their role in the“bottom-up”progression of *** vivid pattern maps and clinical images,this review highlights the crucial role of subchondral bone in driving OA progression,illuminating its interplay with the condition.

关键词： osteoarthritis subchondral bone OPG/RANKL/RANK CXCL12/CXCR4

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transcriptome Profiling of Barley Cultivar Hua 30 MDEC in Response to Agrobacterium Infection

引用

Phyton-International Journal of Experimental Botany 2022年第6期91卷 1153-1164页

作者： Yingbo Li Ting He Guimei guo Hongwei Xu Yingjie Zong Shuwei Zhang Ruiju Lu longhua Zhou Chenghong Liu Biotech Research Institute Shanghai Academy of Agricultural SciencesShanghai201403China Shanghai Key Laboratory of Agricultural Genetics and Breeding Shanghai201106China

Agrobacterium-mediated transformation has been widely used in ***,the mechanism in plant cells’response to Agrobacterium infection was very *** mechanism of the determinants in host cell remains obscure,especially in barley,which is recalcitrant for Agrobacterium-mediated *** the present study,microspore-derived embryogenic calli(MDEC)from barley elite cultivar were employed as unique subjects to characterize the mechanisms during the Agrobacterium infection *** 30 MDEC can be successfully infected by ***-sequencing at different infection points(0,2,6,12,24 hpi)was *** average expressional intensity of the whole genomics increased from 0 to 2 hpi,and then decreased *** upregulated than downregulated differentially expressed genes(DEGs)were counted at the same *** enrichment analysis showed that protein modification was significantly overrepresented in upregulated ***-related biological processes,gene expression and cellular metabolic processes were significantly overrepresented in downregulated *** analysis showed that plant defense responses,phenylpropanoid biosynthesis and biosynthesis of amino acids were significantly enriched across the infection time *** DEGs related to defense responses were *** DEGs were upregulated from 2 to 24 *** speculate that these genes are possibly related to Agrobacterium *** findings will provide deep insights into the molecular events occurring during the process of Agrobacterium-mediated transformation.

关键词： Barley Agrobacterium-mediated transformation microspore-derived embryogenic callus transcriptome analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Control principles of micro-source inverters used in microgrid

引用

Protection and Control of Modern Power Systems 2016年第1期1卷 56-62页

作者： Wenming guo longhua Mu Department of Electrical Engineering Tongji UniversityShanghaiChina

Since micro-sources are mostly interfaced to microgrid by power inverters,this paper gives an insight of the control methods of the micro-source inverters by reviewing some recent ***,the basic principles of different inverter control methods are illustrated by analyzing the electrical circuits and control ***,the main problems and some typical improved schemes of theωU-droop grid-supporting inverter are *** results and discussion part,the comparison of different kinds of inverters is presented and some notable research points is *** is concluded that the most promising control method should be theωU-droop control,and it is meaningful to study the performance improvement methods under realistic operation conditions in the future work.

关键词： Mirogrid Micro-source inverter Droop control Control principle

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phytohormones Accumulation and Distribution in Shoots and Roots of Haploid,Diploid and Tetraploid Barley Seedlings Derived from Microspore Culture

引用

Phyton-International Journal of Experimental Botany 2022年第7期91卷 1419-1428页

作者： longhua Zhou Ting He Jing Li Guimei guo Yingbo Li Hongwei Xu Runhong Gao Linli Huang Yifei Wang Ruiju Lu Zhiwei Chen Chenghong Liu Biotech Research Institute Shanghai Academy of Agricultural SciencesShanghai200000China Biotechnology Research Institute Shanghai Key Laboratory of Agricultural Genetics and BreedingShanghai200000China Shanghai Baixin Biotechnology Company Limited Shanghai200000China

Phytohormones play important roles in plant growth and development,and polyploids are thought to be an important method for plant ***,the relationship between ploidy and phytohormone is still *** this study,barley at three ploidy levels were produced by microspore ***,we further analyzed the phytohormone content in the shoots and roots of the three kinds of barley materials to study the effect of ploidy on phytohormones accumulation and *** results showed that Abscisic acid(ABA),gibberellin(GA),jasmonic acid(JA),auxin(IAA),salicylic acid(SA)and cytokinin(CTK)were successfully determined in shoots and roots using LC-MS(liquid chromatography mass spectrometry).By comparing the shoots of the haploid and diploid plants,it was found that the distribution trend of the six phytohormones was consistent,and another consistent trend was found in the roots of the diploid and tetraploid *** addition,we further analyzed the shoot/root ratio of the different phytohormones to identify the potential differences for haploid,diploid and ***,the relationship between ploidy and phytohormone we provided would provide new insights into understanding the new phenotypes that occur in polyploid species.

关键词： Barley polyploidy microspore culture phytohormone shoot root

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

虹鳟倍性鉴定SSR标记筛选与应用研究

引用

渔业科学进展 2024年第4期45卷 43-52页

作者：马海兵黄天晴徐革锋刘恩慧谷伟王高超郭福元董福霖郑龙华张黎黎姜再胜王炳谦中国水产科学研究院黑龙江水产研究所冷水鱼类产业技术创新战略联盟黑龙江哈尔滨150070 烟台经海海洋渔业有限公司山东烟台264006 安徽省桐城市水产服务中心安徽桐城231400

虹鳟(Oncorhynchusmykiss)是我国冷水性鱼类的主要养殖品种。与二倍体相比,虹鳟三倍体具有生长速度快、肉质好和不育等优点。目前,鉴定虹鳟倍性主要是通过流式细胞术进行DNA含量分析,但这种方法需要采集鱼类血液或组织样本,会对其造成... 详细信息

虹鳟(Oncorhynchusmykiss)是我国冷水性鱼类的主要养殖品种。与二倍体相比,虹鳟三倍体具有生长速度快、肉质好和不育等优点。目前,鉴定虹鳟倍性主要是通过流式细胞术进行DNA含量分析,但这种方法需要采集鱼类血液或组织样本,会对其造成伤害。为了实现利用微创方法收集样本鉴定虹鳟倍性,本研究利用PCR扩增以及电泳分离技术对153个微卫星标记(SSR标记)进行分析,其中139个SSR标记能够在二倍体和三倍体中成功扩增,筛选出132个SSR标记具有多态性,最终鉴定出7个标记在三倍体中表现出较高的变异性。通过在52个已知倍性水平的参考样本和48个未知倍性的样本上进行验证,进一步从中筛选出3个SSR标记(SSR1054、SSR1056和SSR1468)足以区分倍性水平,并且根据3个标记序列重新设计了3对具有良好稳定性的引物序列进行倍性分析应用。本研究所筛选的SSR标记解决了现有虹鳟倍性鉴定中存在的技术流程复杂、耗材昂贵的问题,并有助于不同倍性虹鳟的遗传多样性研究。

关键词：虹鳟鲑科鱼类微卫星三倍体倍性检测

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

考虑灵活控制策略及电流限幅的逆变型分布式电源故障模型

引用

中国电机工程学报 2015年第24期35卷 6359-6367页

作者：郭文明牟龙华同济大学电气工程系上海市嘉定区201804

随着分布式电源(distributed generator,DG)的大规模接入以及并网规约对DG低电压穿越能力的要求,分析DG对故障电网的影响成为一个十分重要的问题。为了得到采用恒功率控制模式的逆变型DG在电网故障条件下的故障模型,首先对DG的控制原理... 详细信息

随着分布式电源(distributed generator,DG)的大规模接入以及并网规约对DG低电压穿越能力的要求,分析DG对故障电网的影响成为一个十分重要的问题。为了得到采用恒功率控制模式的逆变型DG在电网故障条件下的故障模型,首先对DG的控制原理进行了简要分析,然后根据瞬时功率理论和DG输出电流的基本约束推导出DG的通用电流参考信号表达式,调节其中的参数即可实现灵活的控制策略,同时保持DG瞬时功率的平均值对功率参考值的跟踪。在通用电流参考信号表达式的基础上,文章进一步提出了在DG电流限幅条件下功率参考值的计算方法,最后通过Simulink仿真验证了所提出的DG故障模型和限流算法的正确性。

关键词：分布式电源控制策略恒功率控制模式故障模型限流算法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficacy and safety of Tianqi Pingchan Granule, a compound Chinese herbal medicine, for levodopa-induced dyskinesia in Parkinson's disease:A randomized double-blind placebo-controlled trial

引用

Journal of Integrative Medicine 2024年第5期22卷 545-551页

作者： Yu Zhang Xiao-bo Zhu Yang Zhao Gui-yun Cui Wen-tao Li Can-xing Yuan Jian-ping Huang Ying Wan Na Wu Lu Song Jia-hao Zhao Yan Liang Chuan-ying Xu Mei-juan Liu Chen Gao Xin-xin Chen Zhen-guo Liu Department of Neurology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Department of Neurology Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Parkinson's Disease Center the Affiliated Hospital of Xuzhou Medical University Department of Neurology Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine Department of Neurology Longhua HospitalShanghai University of Traditional Chinese Medicine Department of Neurology Wenzhou Central Hospital

Background: Patients with Parkinson's disease(PD) undergoing long-term levodopa therapy are prone to develop levodopa-induced dyskinesia(LID). Amantadine is the main drug recommended for the treatment of LID by current guidelines, but it is far from meeting clinical needs. Tianqi Pingchan Granule(TPG), a compound Chinese herbal medicine, has been developed to relieve symptom of ***: This randomized controlled trial evaluated the efficacy and safety of the combination of TPG and amantadine for ***, setting, participants and interventions: This is a randomized double-blind placebo-controlled trial,conducted from January 2020 to August 2021 at 6 sites in Jiangsu, Zhejiang and Shanghai, China. One hundred PD patients with ≥ 0.5 h of LID were randomly assigned to either the TPG plus amantadine group(TPG group) or the placebo plus amantadine group(placebo group), and treated for a period of12 weeks. To ensure unbiased results, all study participants, investigators and sponsors were unaware of group allocations. Additionally, the data analysts remained blinded until the analysis was *** outcome measures: The primary outcome was assessed using the Unified Dyskinesia Rating Scale(UDysRS)(Range 0–104). The key secondary end point was improvement of motor and non-motor symptoms. Safety analyses included all enrolled ***: One hundred patients were enrolled and randomized into the two treatment groups. The changes in UDysRS at week 12 were –11.02 for the TPG group and –4.19 for the placebo group(treatment difference –6.83 [–10.53 to –3.12]; P = 0.0004). Adverse events were reported for 2 of 50 patients(4.0%) in each of the ***: This study indicated that a 12-week treatment of amantadine plus TPG effectively reduced UDysRS scores and was well tolerated, demonstrating the efficacy and safety of TPG for the treatment of LID in PD.

关键词： Levodopa-induced dyskinesia Parkinson’s disease Tianqi Pingchan Granule

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：