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Production Dynamic Prediction Method of Waterflooding Reservoir Based on Deep Convolution Generative Adversarial Network(DC-GAN)

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Energy Engineering 2022年第5期119卷 1905-1922页

作者： liyuan Xin Xiang Rao Xiaoyin peng Yunfeng Xu Jiating Chen Cooperative Innovation Center of Unconventional Oil and Gas(Ministry of Education&Hubei Province) Yangtze UniversityWuhan430100China Key Laboratory of Drilling and Production Engineering for Oil and Gas Wuhan430100China School of Petroleum Engineering Yangtze UniversityWuhan430100China

The rapid production dynamic prediction of water-flooding reservoirs based on well location deployment has been the basis of production optimization of water-flooding *** that the construction of geological models with traditional numerical simulation software is complicated,the computational efficiency of the simulation calculation is often low,and the numerical simulation tools need to be repeated iteratively in the process of model optimization,machine learning methods have been used for fast reservoir ***,traditional artificial neural network(ANN)has large degrees of freedom,slow convergence speed,and complex network *** paper aims to predict the production performance of water flooding reservoirs based on a deep convolutional generative adversarial network(DC-GAN)model,and establish a dynamic mapping relationship between well location deployment and output oil *** network structure is based on an improved U-Net *** a deep convolutional network and deconvolution network,the features of input well deployment images are extracted,and the stability of the adversarial model is *** training speed and accuracy of the proxy model are improved,and the oil saturation of water flooding reservoirs is dynamically *** results show that the trained DC-GAN has significant advantages in predicting oil saturation by the well-location employment *** cosine similarity between the oil saturation map given by the trained DC-GAN and the oil saturation map generated by the numerical simulator is *** above,DC-GAN is an effective method to conduct a proxy model to quickly predict the production performance of water flooding reservoirs.

关键词： Waterflooding reservoir well location deployment dynamic prediction DC-GAN

Long-term In Vivo Monitoring of Chemicals with Fiber Sensors

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Advanced Fiber Materials 2021年第1期3卷 47-58页

作者： Jiajia Wang liyuan Wang Jianyou Feng Chengqiang Tang Xuemei Sun Huisheng peng State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Scienceand Laboratory of Advanced MaterialsFudan UniversityShanghai 200438China

Long-term in vivo monitoring of chemicals with implanted sensors has received considerable interests over the past decades owing to their significant contributions in reflecting health conditions and assistance in diagnosing ***,the widely explored chemical sensors outside the body fail to meet the requirements of in vivo *** perspective reviews main challenges,recent advances and future directions of long-term in vivo monitoring of chemicals,related to immune response and sensing *** in terms of the immune response caused by unstable interfaces between sensors and tissues and improper implanting methods,and the insufficient performance of chemical sensors in complex physiological environment are ***,recent advances in fabricating biocompatible,flexible and thin sensors,developing effective implanting methods with reduced injury and improving the sensitivity,selectivity and stability of chemical sensors for accurate monitoring in vivo are ***,we propose the future directions to address these challenges by fiber chemical sensors through the combination of soft fiber configuration,facile implanting methods and new recognition elements,which will provide new platforms for health monitoring and physiological mechanism revealing.

关键词： Fiber sensor Long-term Chemical In vivo

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生物育种在玉米逆境胁迫中的研究进展

吉林农业大学学报 2024年第1期46卷 1-9页

作者：关淑艳姜青平韩利圆魏小童焦鹏刘思言马义勇吉林农业大学农学院长春130118 吉林农业大学生命科学学院长春130118

玉米(Zea mays L.)是重要的粮食作物和饲料作物,不同生长阶段逆境会影响玉米植株的生长,从而对玉米产量产生负面影响。从育种选择到应用生物技术手段方面提高植物对逆境胁迫的适应能力,可以增加农作物产量、保护生态系统的稳定性,并为... 详细信息

玉米(Zea mays L.)是重要的粮食作物和饲料作物,不同生长阶段逆境会影响玉米植株的生长,从而对玉米产量产生负面影响。从育种选择到应用生物技术手段方面提高植物对逆境胁迫的适应能力,可以增加农作物产量、保护生态系统的稳定性,并为全球粮食安全做出贡献。对玉米育种的发展历程及生物育种中不同育种技术的优缺点进行概述,论述了生物育种在生物与非生物胁迫等逆境情况下的研究进展,同时以多学科交叉技术的整合为特征,将育种技术与信息技术相结合,展望了未来育种的发展方向和策略及生物育种在解决全球粮食安全方面所起的重要作用,以期为育种技术的革新提供有意义的帮助。

关键词：生物育种玉米逆境胁迫

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糖尿病大鼠肺脏微循环通透性的变化及其意义

中国医药导报 2014年第3期11卷 23-26,F0003页

作者：彭丽媛王海澜翟芳龙谢再明王明君遵义医学院附属深圳市龙岗中心医院广东深圳518116 广东省深圳市儿童医院广东深圳518000

目的观察实验性糖尿病大鼠肺脏微血管通透性的变化,为临床提供糖尿病肺病的形态学依据。方法雄性SD大鼠共60只,体重(220±20)g,按65 mg/kg的剂量一次性腹腔注射链脲菌素(STZ)来制备糖尿病大鼠模型,在成模即刻(0周)、成模后2、4、8、12... 详细信息

目的观察实验性糖尿病大鼠肺脏微血管通透性的变化,为临床提供糖尿病肺病的形态学依据。方法雄性SD大鼠共60只,体重(220±20)g,按65 mg/kg的剂量一次性腹腔注射链脲菌素(STZ)来制备糖尿病大鼠模型,在成模即刻(0周)、成模后2、4、8、12周时分别随机抽取12只,通过干湿重法、尾静脉注入伊文思蓝(EB)并心脏灌注后在分光光度计下测肺组织OD值以及荧光显微镜下测其荧光量来了解肺脏微血管的通透性。另随机抽取12只大鼠作为正常组。结果①与正常组比较,0周组、2周组糖尿病大鼠肺组织的干湿重稍有增加,但差异无统计学意义(P>0.05)。而4周组、8周组和12周组糖尿病大鼠出现了组织干湿重明显增加,差异有统计学意义(P0.05)。从4周开始,糖尿病大鼠出现肺组织EB含量明显增加,差异有统计学意义(P<0.05)。③荧光显微镜下观察肺腑组织荧光量可见4、8、12周组大鼠肺脏组织出现较强的红色荧光。结论糖尿病导致大鼠肺脏微血管通透性发生了变化。

关键词：糖尿病糖尿病肺病微循环障碍伊文思蓝通透性

A strongly interactive adatom/substrate interface for dendrite-free and high-rate Li metal anodes

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Journal of Energy Chemistry 2021年第11期30卷 179-190,I0004页

作者： Shun Li Zhendong Li liyuan Huai Mingming Ma Kailin Luo Jiahe Chen Deyu Wang Zhe peng Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201ZhejiangChina Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China C Innovation Laboratory Contemporary Amperex Technology Ltd.(CATL)Ningde 352100FujianChina Key Laboratory of Optoelectronic Chemical Materials and Devices School of Chemical and Environmental EngineeringJianghan UniversityWuhan 430056HubeiChina

Lithium (Li) metal is considered as one of the most promising anode materials to build next-generation high-energy–density batteries. Nonetheless, dendritic Li deposition has dramatically hindered the practical applications of Li metal batteries (LMBs). Uniformizing Li deposition is a prerequisite to achieve safe and practical LMBs. Herein, an underpotential deposition (UPD) process is first proposed to alter the kinetic and uniformity of Li deposition morphology. Based on the strong interaction between the Li adatoms and manganese (Mn) based substrate, a competition between the UPD and bulk Li deposition is observed, on which the predominance of the UPD scenario tends to uniformize Li nucleation and deposition by the surface coverage of Li monolayers at potentials that are more positive than the Nernst potential of Li metal. Inspired by this process, an advanced hybrid Mn-graphene oxide structure is developed for Li protection, not only enabling dendrite-free Li anodes for high-capacity and -current density cycling, but also improving the interfacial kinetic of Li metal anodes at subzero temperatures, showing potential applicability in low temperature conditions.

关键词： Lithium metal battery Lithium metal anode Lithium dendrite Bulk lithium deposition Underpotential deposition

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中草药对水产动物致病菌抑杀作用的研究进展

水产养殖 2016年第10期37卷 48-52页

作者：徐丰都彭丽园蔡婷胡梁及周泽琴朱盛山广东药科大学中药开发研究所广州510006

查阅近年来中药抑菌试验的相关文献,分别从中草药体外抑制弧菌属、气单胞菌属、爱德华氏菌属、黄杆菌属、假单胞菌属中的致病菌阐述,并归纳总结其运用中存在的问题;在体外抑菌试验中,五倍子和黄连对弧菌属致病菌的抑、杀效果较好;五倍... 详细信息

查阅近年来中药抑菌试验的相关文献,分别从中草药体外抑制弧菌属、气单胞菌属、爱德华氏菌属、黄杆菌属、假单胞菌属中的致病菌阐述,并归纳总结其运用中存在的问题;在体外抑菌试验中,五倍子和黄连对弧菌属致病菌的抑、杀效果较好;五倍子、五味子、乌梅对气单胞菌属致病菌的抑、杀作用较好;五倍子、诃子对爱德华氏菌属致病菌的杀菌作用较强;黄连、大黄对黄杆菌属致病菌的抑、杀效果理想;宣木瓜等对假单孢菌属致病菌的抑、杀作用较好;中草药对常见的水产动物致病菌体外抑、杀效果理想,体内抑菌效果有待进一步研究,在水产养殖领域的运用具有研究价值。

关键词：中草药致病菌最低抑菌浓度最低杀菌浓度

A soluble pH-responsive host-guest-based nanosystem for homogeneous exosomes capture with high-efficiency

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中国化学快报:英文版 2023年第8期34卷 296-301页

作者： Haiyan Wang peng Liang Lei Zhang Liping Shi Yitong Ge liyuan Zhang Xiaoqiang Qiao College of Pharmaceutical Sciences Key Laboratory of Public Health Safety of Hebei ProvinceKey Laboratory of Medicinal Chemistry and Molecular DiagnosisMinistry of EducationHebei UniversityBaoding 071002China College of Basic Medical Science Key Laboratory for Proteomics of Liaoning ProvinceDalian Medical UniversityDalian 116044China

Exosomes offer ideal biomarkers for liquid ***,high-efficient capture of exosomes has been proven to be extreme ***,we report a soluble pH-responsive host-guest-based nanosystem(pH-HGN)for homogeneous isolation of exosomes around physiological *** pH-HGN consists of two specifically functionalized ***,a pH-responsive module,poly-dimethylaminoethyl methacrylate,provides homogeneous capture circumstances and sharp pH-triggered self-assembly separation in aqueous solution to improve capture efficiency and reduce nonspecific ***,a host-guest module,poly-acrylamide azobenzene andβ-cyclodextrin linked with exosomes-specific antibody,could act as the"cleavable bridge"to specific capture and subsequent rapid release of captured exosomes through host-guest interaction betweenβ-cyclodextrin and AAAB *** pH-HGN offered high capture efficiencies for exosomes from two different cell lines,which were 90.2%±0.28%and 87.0%±4.6%for H1299 and MCF-7 cell-derived exosomes,*** purity of isolated exosomes was(1.49±0.71)×10^(11)particles/μg,which was 4.1 times higher compared with the gold standard ultracentrifugation(UC)***,the isolated exosomes via the pH-HGN can preserve well integrity and biological *** developed pH-HGN was further successfully applied to differentiate lung cancer patients from healthy *** findings indicated that pH-HGN is a promising strategy in exosomes-based research and downstream applications.

关键词： Exosomes Homogeneous capture Soluble nanosystem pH-responsive polymer Host-guest interaction

Improving herdsmen’s well-being through scenario planning:A case study in Xilinhot City,Inner Mongolia Autonomous Region

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Geography and Sustainability 2020年第3期1卷 181-188页

作者： Jiajia Liu Ganlin Huang peng Jia liyuan Chen Center for Human-Environment System Sustainability(CHESS) State Key Laboratory of Earth Surface Processes and Resource Ecology(ESPRE)Beijing Normal UniversityBeijing 100875China School of Natural Resources Faculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China Beijing No.142 Middle School(Beijing Hongzhi Middle School) Beijing 100013China Department of Land Surveying and Geo‐Informatics The Hong Kong Polytechnic UniversityHong KongChina International Institute of Spatial Lifecourse Epidemiology(ISLE) Hong KongChina

Grassland ecosystems support well-being with food,shelter,income,and culture of *** the associa-tion between ecosystem services and human well-being has been widely studied,such association is understudied in grassland *** study aims to fill this gap through a case study of Xilinhot City,Inner Mongolia Autonomous Region,*** examined the association between grassland provisioning services and herds-men’s well-being between 1985 and 2015 through participatory observations,interviews,surveys,and Bayesian belief network *** the uncertainties of weather and sheep prices,we developed four scenarios to examine the future well-being of *** results show that the most important factor for herdsmen’s well-being was income,which is highly sensitive to the market price of sheep and *** the uncertainties of sheep prices and precipitation,scenario analysis revealed a divergence between income and *** herdsmen’s income is most likely to increase with low precipitation and increased sheep prices,their well-being is most likely to improve with abundant precipitation and increased sheep *** on our find-ings,we argue that developing alternative income sources(e.g.,tourism),reducing dependence on government subsidies through commercial insurance,and branding lamb with grassland ecosystem to alleviate the impact of price fluctuations would help improve herdsmen’s well-being in all scenarios.

关键词： Grassland Ecosystem service Well-being Bayesian belief network model Scenario planning Inner Mongolia

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基于生物资源的万山海洋牧场生境适宜性评估

海洋科学 2024年第1期48卷 75-84页

作者：初建松郑卫东孙利元彭道民索安宁朱玉贵中国海洋大学海洋生命学院山东青岛266003 山东省渔业发展和资源养护总站山东烟台264003 中国科学院南海海洋研究所广东广州510301 中国海洋大学水产学院山东青岛266003

万山群岛海域生态环境日益恶化、渔业资源持续衰退,因此建设万山群岛海洋牧场,修复海域生态环境、实现渔业资源可持续利用迫在眉睫。针对现阶段基于海洋生物资源的海洋牧场适宜性评估的研究较少,本研究利用渔业资源调查和全球物种数据... 详细信息

万山群岛海域生态环境日益恶化、渔业资源持续衰退,因此建设万山群岛海洋牧场,修复海域生态环境、实现渔业资源可持续利用迫在眉睫。针对现阶段基于海洋生物资源的海洋牧场适宜性评估的研究较少,本研究利用渔业资源调查和全球物种数据库记录数据及13个环境因素数据,采用物种分布模型MaxEnt对选择的白姑鱼、日本金线鱼、红星梭子蟹和浅缝骨螺潜在分布区进行预测,探讨海洋生物地理分布与海洋环境因素之间的关系进而进行万山海洋牧场生境适宜性评估,结果表明:(1)各模型AUC值均大于0.9,说明构建的模型对这些物种潜在分布的模拟效果较好,后续可采用MaxEnt模型对4种生物的栖息地分布区进行预测;(2)海底浮游植物密度、海底温度以及海底硅酸盐浓度是影响这4种海洋生物栖息地分布的关键环境因子;(3)基于该4种海洋物种MaxEnt模型的HSI分布区所存在重叠区域来看,海洋牧场拟建设区域应为纬度21.85°N~22.15°N,经度113.6°E~114.2°E。研究结果可为万山海洋牧场规划和建设提供科学依据。

关键词：海洋牧场万山群岛适宜性评估 MaxEnt模型