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Science Bulletin 2016年第17期61卷 1384-1390页

作者： liyang zhang Bei Xu Zhiwen Luo Wen Liao Key Laboratory of Orogenic Belts and Crustal Evolution Ministry of Education School of Earth and Space Sciences Peking University Beijing 100871 China

New U-Pb zircon geochronology data suggest that the Yintun Formation is younger man ~ 1895 Ma and is late *** Yintun Formation may represent the first sedimentary cover of the North China Craton(NCC)based on its stratigraphic sequence and the ages of its *** in the conglomerates from the lower member of the Yintun Formation are characterized by obvious glacial *** is possible that these glacial gravels are the re-deposited sedimentary products of the Huronian Glaciation from the Indian *** can also provide sedimentary evidence for the relative location of the Indian continent and the NCC in the reconstruction of the Columbia supercontinent.

关键词： Yintun Formation Huronian Glaciation Columbia supercontinent

Long-Term Consistent Recalibration of VIRR Solar Reflectance Data Record for Fengyun Polar-Orbiting Satellites

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Journal of Meteorological Research 2021年第6期35卷 926-942页

作者： Ling SUN Hong QIU Ronghua WU Jing WANG liyang zhang Peng zhang National Satellite Meteorological Center China Meteorological AdministrationBeijing 100081

The visible infrared radiometer(VIRR)is the first instrument with longest measurements equipped on the Fengyun(FY)polar-orbiting *** re-processing of the historic VIRR measurements,long-term(over 20 yr)global data can be integrated from multiple participating VIRRs on a consistent radiometric scale,which are valuable to climate and climate change *** to lack of an onboard calibration system for VIRR,the reflective solar bands must be vicariously *** study applied the multi-site vicarious approach for consistent calibration of the VIRR visible(VIS)and near-infrared(NIR)data,and produced calibration coefficients for five VIRRs on FY-1 C/D and FY-3 A/B/*** data quality was then evaluated with *** reflectance predicted by using the radiative transfer model over multiple invariant desert and ocean targets was used to derive the calibration slope via a weighted fitting scheme,in which the weights are the inverse of the variance from a radiative transfer simulation evaluated with reference to Aqua moderate resolution imaging spectroradiometer(MODIS).The sensor-specific calibration coefficients were derived on a daily basis by using piecewise *** calibration reference of the VIRR solar band record was further traced to the Aqua MODIS Collection 6.1 reference calibration with a systematic correction derived from the Libya4 *** VIRR record was compared with the Aqua MODIS C6.1 calibration over the polar region based on simultaneous nadir overpass *** lifetime relative difference for each sensor are within 3.3%and 4.5%for channels 1 and *** deserts were also employed to evaluate the stability and consistency of the VIRR *** general,the means of the directional and spectral corrected reflectance for each sensor are within 1%of the 20-yr average,implying that the VIRR reflectance of the invariant targets is consistent to within 1%among the sensors for channels 1 and *** VIRR data th

关键词： FY-1 FY-3 visible infrared radiometer(VIRR) reflective solar bands pseudo-invariant calibration sites(PICS) calibration directional model(DM) spectral band adjustment factor(SBAF)

Oxidative modifications and structural changes of human serum albumin in response to air dielectric barrier discharge plasma

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High Voltage 2021年第5期6卷 813-821页

作者： Siqi Peng liyang zhang Dongheyu zhang Yuntao Guo Xinxin Wang Qun Zhou Haiyun Luo Department of Electrical Engineering Tsinghua UniversityBeijingChina Department of Chemistry Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education)Tsinghua UniversityBeijingChina

In this work,the air dielectric barrier discharge plasma was applied to a model of protein human serum albumin to explore plasma‐mediated protein damage from a biomolecular *** and side chain modifications of protein in solution were observed by Fourier transform infrared(FT‐IR)spectroscopy and mass spectrometry(MS).Protein backbone cleavage is proved by Bradford assay,sodium dodecyl sulphate–polyacrylamide gel electrophoresis,and *** fragments are in the range of 10–12 *** decrease inα‐helix and increase inβ‐sheet indicated by FT‐IR are major protein secondary structure ***,a whole map of protein oxidative damage and structural changes in response to the plasma was postulated.

关键词： damage serum barrier

Characteristics of land surface thermal-hydrologic processes for different regions over North China during prevailing summer monsoon period

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Science China Earth Sciences 2012年第9期55卷 1872-1880页

作者： zhang Qiang ZENG Jian zhang liyang Institute of Arid Meteorology of CMA Key laboratory of Arid Climatic Change and Reducing Disaster of Gansu ProvinceKey Open Laboratory of Arid Climatic Change and Disaster Reduction of CMALanzhou 730020China Meteorological Bureau of Gansu Lanzhou 730020China Beijing Meteorological Bureau Beijing 100089China College of Atmospheric Sciences Lanzhou UniversityLanzhou 730000China

The observation stations of Northern China are divided into three regions:the arid Northwest China,the Loess Plateau,and the cool Northeast *** consistencies,differences,and associated mechanisms of land surface thermal-hydrologic processes among the three regions were studied based on the normalization of major variables of land surface thermal-hydrologic processes,using data collected during prevailing summer monsoon period(July and August,2008).It is shown that differences of surface thermal-hydrologic processes are remarkable among the three regions because of different impacts of summer *** their soil wet layers occur at different depths,and the average albedo and its diurnal variations are distinctly *** net short-wave radiation in the Loess Plateau is close to that in the cool Northeast China,but its surface net long-wave radiation is close to that in the arid Northwest *** the ratio of net radiation to global solar radiation in the cool Northeast China is higher than the other two regions,though its temperature is *** are obvious regional differences in the ratios of surface sensible and latent heat fluxes to net radiation for the three regions because of distinct contribution of sensible and latent heat fluxesto land surface energy *** three regions are markedly different in the ratio of water vapor flux to pan evaporation,but they are consistent in the ratio of water vapor flux to *** results not only indicate different influences of climate and environmental factors on land surface thermal-hydrologic processes in the three regions,but also show that summer monsoon is important in the formation and variation of the pattern of land surface thermal-hydrologic processes.

关键词： different regions of North China prevailing summer monsoon period coordinated experiment land surface thermalhydrologic processes influence factors

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Stimuli-responsive microcarriers and their application in tissue repair: A review of magnetic and electroactive microcarrier

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Bioactive Materials 2024年第9期39卷 147-162页

作者： liyang zhang Mengjiao Ma Junfei Li Kun Qiao Yajie Xie Yudong Zheng School of Material Science and Engineering University of Science and Technology BeijingBeijingChina Beijing Wanjie Medical Device Co. LtdBeijingChina Beijing Gerecov Technology Company Ltd. BeijingChina

Microcarrier applications have made great advances in tissue engineering in recent years, which can load cells,drugs, and bioactive factors. These microcarriers can be minimally injected into the defect to help reconstruct agood microenvironment for tissue repair. In order to achieve more ideal performance and face more complextissue damage, an increasing amount of effort has been focused on microcarriers that can actively respond toexternal stimuli. These microcarriers have the functions of directional movement, targeted enrichment, materialrelease control, and providing signals conducive to tissue repair. Given the high controllability and designabilityof magnetic and electroactive microcarriers, the research progress of these microcarriers is highlighted in thisreview. Their structure, function and applications, potential tissue repair mechanisms, and challenges are *** summary, through the design with clinical translation ability, meaningful and comprehensiveexperimental characterization, and in-depth study and application of tissue repair mechanisms, stimuliresponsivemicrocarriers have great potential in tissue repair.

关键词： Stimuli-responsiveness Magnetic microcarrier Electroactive microcarrier Tissue repair

Determination of dietary copper requirement by the monoamine oxidase activity in kidney of broilers from 1 to 21 days of age

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Animal Nutrition 2022年第1期8卷 227-234页

作者： Yun Hu Zhiyong Chen Lin Lu liyang zhang Tao Liu Xugang Luo Xiudong Liao Poultry Mineral Nutrition Laboratory College of Animal Science and TechnologyYangzhou UniversityYangzhou225000China Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing100193China Biochemistry Department Case Western Reserve UniversityCleveland44106USA

The current dietary copper(Cu)requirement(8 mg/kg)of broilers is mainly based on growth,hemoglobin concentration,or hematocrit,which might not be the most sensitive indices to evaluate dietary Cu requirements of *** present study was carried out to estimate dietary Cu requirements of broilers fed a conventional corn-soybean meal diet from 1 to 21 d of age using biochemical or molecular biomarkers.A total of 3841-d-old Arbor Acres male broilers were randomly allocated to 1 of 6 treatments with 8 replicates and fed a Cu-unsupplemented corn-soybean meal basal diet containing 5.17 mg Cu/kg by analysis and the basal diet supplemented with 3,6,9,12 or 15 mg Cu/kg as CuSO4,5H2O for 21 *** analysis was performed to estimate the optimal dietary Cu level using the broken-line *** supplemental Cu level affected(P0.05)on the growth performance,Cu contents in heart,kidney,pancreas and spleen,Cu-and zinc-containing superoxide dismutase(CuZnSOD)activity and ceruloplasmin content in serum,CuZnSOD and cytochrome c oxidase(COX)activities and ceruloplasmin,CuZnSOD,MAO A,MAO B,COX 4I1 and COX 1 mRNA and protein expressions in the above tissues of *** dietary supplemental Cu levels increased,Cu contents in serum and liver increased linearly(P<0.05),but kidney MAO activity decreased linearly and quadratically(P<0.05).The estimated dietary Cu requirement based on the fitted broken-line model(P=0.035)of kidney MAO activity was 11.30 mg/*** conclusion,kidney MAO activity is a new and sensitive criterion to evaluate the dietary Cu requirement of broilers,and the dietary Cu requirement was 11.30 mg/kg for broilers fed the conventional corn-soybean meal diet from 1 to 21 d of age,which is higher than the current National Research Council(NRC)Cu requirement(8 mg/kg)of broilers.

关键词： Copper Monoamine oxidase Requirement Broilers

Metabolic utilization of intravenously injected iron from different iron sources in target tissues of broiler chickens

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Animal Nutrition 2022年第2期9卷 74-83页

作者： Lin Lu Xueyu Dong Xuelian Ma liyang zhang Sufen Li Xugang Luo Xiudong Liao Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing100193China Poultry Mineral Nutrition Laboratory College of Animal Science and TechnologyYangzhou UniversityYangzhou225000China Department of Animal Science Hebei Normal University of Science and TechnologyQinhuangdao066004China

No information is available regarding the utilization of iron (Fe) from different Fe sources at a targettissue level. To detect differences in Fe metabolic utilization among Fe sources, the effect of intravenouslyinjected Fe on growth performance, hematological indices, tissue Fe concentrations and Fe-containingenzyme activities and gene expressions of Fe-containing enzymes or protein in broilers was *** d 22 post-hatching, a total of 432 male chickens were randomly allotted to 1 of 9 treatments ina completely randomized design. Chickens were injected with either a 0.9% (wt/vol) NaCl solution(control) or a 0.9% NaCl solution supplemented with Fe sulphate or 1 of 3 organic Fe sources. The 3organic Fe sources were Fe chelates with weak (Fe-MetW), moderate (Fe-ProtM) or extremely strong (Fe-ProtES) chelation strength. The 2 Fe dosages were calculated according to the Fe absorbabilities of 10%and 20% every 2 d for a duration of 20 d. Iron injection did not affect (P > 0.05) ADFI, ADG or FCR duringeither 1 to 10 d or 11 to 20 d after injections. Hematocrit and Fe concentrations in the liver and kidney ond 10 after Fe injections, and Fe concentrations in the liver or pancreas and ferritin heavy-chain (FTH1)protein expression level in the liver or spleen on d 20 after Fe injections increased (P≤0.05) as injectedFe dosages increased. When the injected Fe level was high at 20% Fe absorbability, the chickens injectedwith Fe-ProtES had lower (P < 0.001) liver or kidney Fe concentrations and spleen FTH1 protein levelsthan those injected with Fe-MetW or Fe-ProtM on d 20 after injections. And they had lower (P < 0.05)liver cytochrome C oxidase mRNA levels on d 20 after injections than those injected with Fe-MetW or Fesulphate. The results from this study indicate that intravenously injected Fe from Fe-ProtES was the least utilizable and functioned in the sensitive target tissue less effectively than Fe from Fe sulfate, Fe-MetW or Fe-ProtM.

关键词： Intravenous injection Iron-containing protein Gene expression Iron source Broiler

Regulation of bone phosphorus retention and bone development possibly by related hormones and local bone-derived regulators in broiler chicks

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Journal of Animal Science and Biotechnology 2022年第1期13卷 224-239页

作者： Sumei Cao Tingting Li Yuxin Shao liyang zhang Lin Lu Rijun zhang Shuisheng Hou Xugang Luo Xiudong Liao Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing 100193People’s Republic of China Poultry Mineral Nutrition Laboratory College of Animal Science and TechnologyYangzhou UniversityYangzhou 225000People’s Republic of China Laboratory of Feed Biotechnology State Key Laboratory of Animal NutritionCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193People’s Republic of China

Background:Phosphorus is essential for bone mineralization in broilers,however,the underlying mechanisms remain *** aimed to investigate whether bone phosphorus retention and bone development might be regulated by related hormones and local bone-derived regulators in ***:Broilers were fed diets containing different levels of non-phytate phosphorus(NPP)0.15%,0.25%,0.35%,0.45% and 0.55% or 0.15%,0.22%,0.29%,0.36% and 0.43% from 1 to 21 or 22 to 42 days of *** and tibia samples were collected for determinations of bone phosphorus retention and bone development parameters,related hormones and local bone-derived regulators of broiler chickens on d 14,28 and 42,***:Tibia ash phosphorus,total phosphorus accumulation in tibia ash(TP_(TA)),bone mineral concentration(BMC),bone mineral density(BMD),bone breaking strength(BBS),and ash on d 14,28 or 42,serum 1,25-dihydroxyvitamin D_(3)(1,25(OH)_(2)D_(3))on d 28 and 42,mRNA expressions of tibia fibroblast growth factor 23(FGF23)and dentin matrix protein 1(DMP1)on d 14 and 28 increased linearly or quadratically(P<0.05),while serum parathyroid hormone(PTH)on d 28,tibia alkaline phosphatase(ALP)on d 14,28 and 42,bone gal protein(BGP)on d 14,and mRNA expression of tibia phosphate-regulating gene with homologies to endopeptidases on the X chromosome(PHEX)on d 14 and 28 decreased linearly or quadratically(P<0.04)as dietary NPP level ***,BMC,BMD,and ash on d 28 and 42,BBS on d 28,and ash phosphorus on d 42 were positively correlated(r=0.389 to 0.486,P<0.03)with serum 1,25(OH)_(2)D_(3).All of the above parameters were positively correlated(r=0.380 to 0.689,P<0.05)with tibia DMP1 mRNA expression on d 14,28 and 42,but negatively correlated(r=−0.609 to−0.538,P<0.02)with serum PTH on d 28,tibia ALP on d 14,28 and 42,and BGP on d ***_(TA),BMC and ash on d 14 and BMD on d 28 were negatively correlated(r=−0.397 to−0.362,P<0.03)with tibia PHEX mRNA expression,and BMD on d 28 was positively

关键词： Bone Broiler chicken Hormone Local bone-derived regulator Phosphorus

Dietary manganese supplementation inhibits abdominal fat deposition possibly by regulating gene expression and enzyme activity involved in lipid metabolism in the abdominal fat of broilers

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Journal of Integrative Agriculture 2024年第12期23卷 4161-4171页

作者： Xiaoyan Cui Ke Yang Weiyun zhang liyang zhang Ding Li Wei Wu Yun Hu Tingting Li Xugang Luo Poultry Mineral Nutrition Laboratory College of Animal Science and TechnologyYangzhou UniversityYangzhou 225009China Department of Animal Science Hebei Normal University of Science and TechnologyQinhuangdao 066004China Hebei Provincial Key Laboratory of Characteristic Animal Germplasm Resources Mining and Innovation Qinhuangdao 066004China Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing 100193China

Excessive abdominal fat deposition seriously restricts the production efficiency of *** studies found that dietary supplemental manganese(Mn)could effectively reduce the abdominal fat deposition of broilers,but the underlying mechanisms remain *** present study aimed to investigate the effect of dietary supplementation with the inorganic or organic Mn on abdominal fat deposition,and enzyme activity and gene expression involved in lipid metabolism in the abdominal fat of male or female broilers.A total of 4201-d-old AA broilers(half males and half females)were randomly allotted by body weight and gender to 1 of 6 treatments with 10 replicates cages of 7 chicks per cage in a completely randomized design involving a 3(dietary Mn addition)×2(gender)factorial *** or female broilers were fed with the Mn-unsupplemented basal diets containing 17.52 mg Mn kg^(-1)(d 1-21)and 15.62 mg Mn kg^(-1)(d 22-42)by analysis or the basal diets supplemented with 110 mg Mn kg^(-1)(d 1-21)and 80 mg Mn kg^(-1)(d 22-42)as either the Mn sulfate or the Mn proteinate with moderate chelation strength(Mn-Prot M)for 42 *** results showed that the interaction between dietary Mn addition and gender had no impact(P>0.05)on any of the measured parameters;abdominal fat percentage of broilers was decreased(P<0.003)by Mn addition;Mn addition increased(P<0.004)adipose triglyceride lipase(ATGL)activity,while Mn-Prot M decreased(P<0.002)the fatty acid synthase(FAS)activity in the abdominal fat of broilers compared to the control;Mn addition decreased(P<0.009)diacylglycerol acyltransferase 2(DGAT2)mRNA expression level and peroxisome proliferator-activated receptor γ(PPARγ)mRNA and protein expression levels,but up-regulated(P<0.05)the ATGL mRNA and protein expression levels in the abdominal fat of *** was concluded that dietary supplementation with Mn inhibited the abdominal fat deposition of broilers possibly via decreasing the expression of PPARγand DGAT2 as well

关键词： manganese abdominal fat broiler gene expression enzyme activity

Determination of optimal dietary selenium levels by full expression of selenoproteins in various tissues of broilers from 1 to 21 d of age

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Animal Nutrition 2021年第4期7卷 1133-1144页

作者： Xiudong Liao Guoqing Liu Guangming Sun Xiaoming Sun Tao Liu Lin Lu liyang zhang Minhong zhang Yanli Guo Xugang Luo Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijingChina Poultry Mineral Nutrition Laboratory College of Animal Science and TechnologyYangzhou UniversityYangzhouChina College of Animal Science and Technology Gansu Agricultural UniversityLanzhouChina Biochemistry Department Case Western Reserve UniversityClevelandUSA State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement LhasaChina Institute of Animal Science and Veterinary Tibet Academy of Agricultural and Animal Husbandry SciencesLhasaChina

The current NRC dietary selenium(Se)requirement(0.15 mg/kg)of broilers is primarily based on growth performance data reported in *** study aimed to determine optimal dietary Se levels of broilers fed a practical corn-soybean meal diet for the full expression of selenoproteins in various tissues.A total of 384 one-d-old male broilers(n=8 replicates/diet)were fed a basal corn-soybean meal diet or the basal diet supplemented with 0.1,0.2,0.3,0.4 or 0.5 mg Se/kg in the form of Na_(2)SeO_(3) for 21 *** analysis was conducted to evaluate the optimal dietary Se levels using broken-line,quadratic or asymptotic *** activity of glutathione peroxidase(GPX)in the plasma,liver,kidney and pancreas,iodothyronine deiodinase(DIO)in the plasma,liver and pancreas,and thioredoxin reductase(Txnrd)in the liver and pancreas,the mRNA levels of Gpx1,Gpx4,Dio1,selenoprotein(Seleno)h,Selenop and Selenou in the liver,Gpx4,Dio1,Txnrd1,Txnrd2,Selenoh,Selenop and Selenou in the kidney,and Gpx1,Gpx4,Selenoh and Selenou in the pancreas,and the protein levels of GPX4 in the liver and kidney of broilers were influenced(P<0.05)by added Se levels,and increased quadratically(P<0.05)with the increase of added Se *** estimates of optimal dietary Se levels were 0.07 to 0.36 mg/kg based on the fitted broken-line,quadratic or asymptotic models(P<0.001)of the aforementioned selenoprotein expression in the plasma,liver and kidney,and 0.09 to 0.46 mg/kg based on the fitted broken-line models(P<0.001)of the aforementioned selenoprotein expression in the *** results indicate that the optimal dietary Se levels would be 0.36 mg/kg to support the full expression of selenoproteins in the plasma,liver and kidney,and 0.46 mg/kg to support the full expression of selenoproteins in the pancreas of broilers fed a practical corn-soybean meal diet from 1 to 21 d of age.

关键词： Selenium Selenoprotein Gene expression Requirement Broiler