Stimuli-responsive microcarriers and their application in tissue repair: A review of magnetic and electroactive microcarrier
作者机构:School of Material Science and EngineeringUniversity of Science and Technology BeijingBeijingChina Beijing Wanjie Medical Device Co.LtdBeijingChina Beijing Gerecov Technology Company Ltd.BeijingChina
出 版 物:《Bioactive Materials》 (生物活性材料(英文))
年 卷 期:2024年第39卷第9期
页 面:147-162页
核心收录:
学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 08[工学] 0836[工学-生物工程]
基 金:supported by National Natural Science Foundation of China(Grant No.52273119,51973018) Key Research and Development Projects of People’s Liberation Army(BWS17J036) Beijing Science and Technology Project(Z191100002019017)
主 题:Stimuli-responsiveness Magnetic microcarrier Electroactive microcarrier Tissue repair
摘 要:Microcarrier applications have made great advances in tissue engineering in recent years, which can load cells,drugs, and bioactive factors. These microcarriers can be minimally injected into the defect to help reconstruct agood microenvironment for tissue repair. In order to achieve more ideal performance and face more complextissue damage, an increasing amount of effort has been focused on microcarriers that can actively respond toexternal stimuli. These microcarriers have the functions of directional movement, targeted enrichment, materialrelease control, and providing signals conducive to tissue repair. Given the high controllability and designabilityof magnetic and electroactive microcarriers, the research progress of these microcarriers is highlighted in thisreview. Their structure, function and applications, potential tissue repair mechanisms, and challenges are *** summary, through the design with clinical translation ability, meaningful and comprehensiveexperimental characterization, and in-depth study and application of tissue repair mechanisms, stimuliresponsivemicrocarriers have great potential in tissue repair.