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科技创新与生产力 2024年第5期45卷 49-51,55页

作者：孟丽霞马秀兰高源阳曲县气象局山西太原030100 五台县气象局山西忻州035502

为了缓解在全球气候变暖背景的影响下,气温升高、降水减少且分布不均、干旱严重,给农作物生长发育造成的影响,本文通过分析阳曲县气象条件对谷子生长发育的影响,同时提出谷子专业气象为农服务对策,以期为谷子优质高产,农民增收提供理论... 详细信息

为了缓解在全球气候变暖背景的影响下,气温升高、降水减少且分布不均、干旱严重,给农作物生长发育造成的影响,本文通过分析阳曲县气象条件对谷子生长发育的影响,同时提出谷子专业气象为农服务对策,以期为谷子优质高产,农民增收提供理论依据。

关键词：谷子气象条件气象服务阳曲县

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FGF23、ANGPTL4、Apelin-13与急性缺血性脑卒中患者病情及溶栓治疗短期预后的相关性

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分子诊断与治疗杂志 2024年第2期16卷 308-312页

作者：孟丽霞郗海涛申红梅首都医科大学附属北京康复医院社区康复中心北京100144

目的探究成纤维生长因子23(FGF23)、血管生成素样蛋白4(ANGPTL4)、Apelin-13与急性缺血性脑卒中(AIS)患者病情及溶栓治疗短期预后的关系。方法选取2020年7月到2023年7月首都医科大学附属北京康复医院收治的120例AIS患者,采用美国国立... 详细信息

目的探究成纤维生长因子23(FGF23)、血管生成素样蛋白4(ANGPTL4)、Apelin-13与急性缺血性脑卒中(AIS)患者病情及溶栓治疗短期预后的关系。方法选取2020年7月到2023年7月首都医科大学附属北京康复医院收治的120例AIS患者,采用美国国立卫生研究院卒中量表(NIHSS)评估患者入院时神经功能损伤程度并分为轻度组35例、中度组54例、重度组31例;采用头颅MRI检查评估患者梗死病灶面积并分为腔隙性脑梗死组31例、中等面积梗死组52例,大面积脑梗死组37例;采用改良Rankin量表评估患者溶栓治疗后90 d的预后情况并分为预后良好组82例和预后不良组38例。比较各组患者血清学指标FGF23、ANGPTL4、Apelin-13水平,采用多因素logistic回归分析AIS患者短期预后影响因素。结果不同神经损伤程度的AIS患者血清FGF23水平为:轻度组中度组>重度组,差异均有统计学意义(F=9.685、8.418、13.695,P中等面积梗死组>大面积脑梗死组,差异均有统计学意义(F=8.652、7.579、18.659,P<0.05);预后不良组年龄、病灶最大直径、入院时NIHSS评分、血清FGF23水平均高于预后良好组,血清ANGPTL4、Apelin-13水平均低于预后良好组,差异均有统计学意义(t=3.147、4.725、7.309、3.364、4.869、5.766,P<0.05);病灶最大直径≥5 cm、入院时NIHSS评分≥20分、高水平FGF23均是AIS患者静脉溶栓治疗短期预后不良的独立危险因素,高水平的ANGPTL4及Apelin-13是其保护因素(P<0.05)。结论 FGF23、ANGPTL4、Apelin-13与AIS患者病情程度及短期预后密切相关,检测三指标水平有助于AIS病情及预后评估。

关键词：急性缺血性脑卒中静脉溶栓成纤维生长因子23 血管生成素样蛋白4 Apelin-13

Silage Fermentation Technology and Its Effects on Growth Performance of Local Pigs

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Asian Agricultural Research 2023年第5期15卷 52-54,57页

作者： Yunjian ZHANG Zhenyan YANG lixia meng Xibao FENG Laiwu District Administrative Law Enforcement Coordination and Supervision Bureau Jinan 271100China Jinan Academy of Agricultural Sciences Jinan 250316China

This paper first introduced the silage fermentation technology,including the selection of strains and activation expansion technology,the screening of high-quality fermentation raw materials,and the comparative experiment of fermentation *** discussed feeding methods for sows and growing-finishing pigs at different breeding *** addition,it analyzed the effects of fermented silage on the growth performance of local pigs at various ***,it is concluded that silage fermentation can improve the water retention performance of pork,improve the quality of pork from local pigs,increase economic benefits,and achieve the purpose of saving costs and increasing efficiency.

关键词： Silage fermentation Strain selection Growth performance Local pigs Pork quality

When to start renal replacement therapy in acute kidney injury: What are we waiting for?

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Journal of Intensive Medicine 2024年第3期4卷 341-346页

作者： lixia Liu Zhenjie Hu Department of Critical Care Medicine The Fourth Hospital of Hebei Medical UniversityShijiazhuangHebeiChina

Acute kidney injury remains a serious condition with a high mortality risk. In the absence of any new drugs, renal replacement therapy (RRT) is the most important treatment option. Randomized controlled trials have concluded that in critically ill patients without an emergency indication for RRT, a watchful waiting strategy is safe;however, further delays in RRT did not seem to confer any benefit, rather was associated with potential harm. During this process, balancing the risks of complications due to an unnecessary intervention with the risk of not correcting a potentially life-threatening complication remains a challenge. Dynamic renal function assessment, especially dynamic assessment of renal demand-capacity matching, combined with renal biomarkers such as neutrophil gelatinase-associated lipocalin and furosemide stress test, is helpful to identify which patients and when the patients may benefit from RRT.

关键词： Acute kidney injury Renal replacement therapy Initiation timing Dynamic assessment Biomarkers

Distribution assessment of soil erosion with revised RUSLE model in Tianshan Mountains

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Journal of Mountain Science 2024年第3期21卷 850-866页

作者： WEI wenyu LIU Ya ZHANG lixia LI Lanhai State Key Laboratory of Desert and Oasis Ecology Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Reaserch Center of Educational in Xinjiang Xinjiang Normal UniversityUrumqi 830017China

aSoil degradation caused by soil erosion is one of the world's most critical environmental *** erosion in the Tianshan Mountains has caused various environmental problems in the surrounding *** study used remote sensing data to analyze the distribution of the factors influencing soil erosion,and the revised universal soil loss equation(RUSLE)to calculate the total amount and distribution characteristics of soil erosion in the Tianshan Mountains in *** to the large error of RUSLE in soil erosion estimation in mountainous areas,this study modified RUSLE equation based on the characteristics of snow cover in the Tianshan *** results show that the average soil erosion was 1690.3 t/(km^(2)·year),of which insignificant erosion,slight erosion and moderate erosion accounted for 42,8%,22.4%and 9.9%,*** erosion and above accounted for 13.3%.The accuracy of the soil erosion modulus calculated by the RUSLE was only 61.9%,with an average error of 1631.9 t/(km^(2)·year).The average error of the double-coefficient correction method was 1259.1 t/(km^(2)·year),and the average error of the modified formula method was reduced by 40.3%compared with the RUSLE,reaching 973.7 t/(km^(2)·year),and its accuracy reached 76.2%.Very severe erosion and catastrophic erosion are distributed on mountain ridges with higher elevation and on the northern area with higher *** cover has a certain inhibitory effect on soil erosion,and snow cover in alpine mountains is a factor that cannot be ignored in soil erosion research.

关键词： RUSLE Snow cover Erosion categories High-elevation area

Assessing the Performance of CMIP6 Models in Simulating Droughts across Global Drylands

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Advances in Atmospheric Sciences 2024年第2期41卷 193-208页

作者： Xiaojing YU lixia ZHANG Tianjun ZHOU Jianghua ZHENG LASG Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044China University of Chinese Academy of Sciences Beijing 100049China College of Geography&Remote Sensing Sciences Xinjiang UniversityUrumqi 830046China

Both the attribution of historical change and future projections of droughts rely heavily on climate modeling. However,reasonable drought simulations have remained a challenge, and the related performances of the current state-of-the-art Coupled Model Intercomparison Project phase 6(CMIP6) models remain unknown. Here, both the strengths and weaknesses of CMIP6 models in simulating droughts and corresponding hydrothermal conditions in drylands are *** the general patterns of simulated meteorological elements in drylands resemble the observations, the annual precipitation is overestimated by ~33%(with a model spread of 2.3%–77.2%), along with an underestimation of potential evapotranspiration(PET) by ~32%(17.5%–47.2%). The water deficit condition, measured by the difference between precipitation and PET, is 50%(29.1%–71.7%) weaker than observations. The CMIP6 models show weaknesses in capturing the climate mean drought characteristics in drylands, particularly with the occurrence and duration largely underestimated in the hyperarid Afro-Asian areas. Nonetheless, the drought-associated meteorological anomalies, including reduced precipitation, warmer temperatures, higher evaporative demand, and increased water deficit conditions, are reasonably reproduced. The simulated magnitude of precipitation(water deficit) associated with dryland droughts is overestimated by 28%(24%) compared to observations. The observed increasing trends in drought fractional area,occurrence, and corresponding meteorological anomalies during 1980–2014 are reasonably reproduced. Still, the increase in drought characteristics, associated precipitation and water deficit are obviously underestimated after the late 1990s,especially for mild and moderate droughts, indicative of a weaker response of dryland drought changes to global warming in CMIP6 models. Our results suggest that it is imperative to employ bias correction approaches in drought-related studies over drylands by using CMIP6 o

关键词： droughts hydrothermal conditions drylands CMIP6 model evaluation

Optimization on crystallization process of the magnetic core lysozyme

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Particuology 2024年第4期87卷 106-113页

作者： lixia Hou Chunxiao Qu Min Su Zhihan Liang Qi Hao School of Chemical Engineering Hebei University of TechnologyTianjin300130China

The continuous growth of the biomedical market highlights the significance of improvement in the ef-ficiency of batch production for protein drug ***,we investigated the effect of polymer-modified Fe_(3)O_(4) nanoparticles on lysozyme(Lys)crystallization at different conditions,using function-alized Fe_(3)O_(4) magnetic nanoparticles(Polymer C@Fe_(3)O_(4))as nucleation *** study revealed that the surface charge density of Polymer C@Fe_(3)O_(4) was highest at a modification mass ratio of Fe_(3)O_(4) to Polymer C is 8∶*** ratio facilitates the augmentation of electrostatic interaction and the promotion of *** adding 15%of the PolymerC@Fe_(3)O_(4) prepared from Fe_(3)O_(4) with an average particle size of 150 nm,the magnetic core lysozyme(M-Lys)crystals with an average particle size of 11.08μm,narrow size distribution,and regular morphology were obtained in a yield of 82.42%within 60 min.

关键词： Protein Crystallization Magnetic particle Lysozyme

Melittin enhanced intracellular trehalose with synergistic membrane stabilization of macromolecular protectants for cell cryopreservation

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Science China(Technological Sciences) 2024年第4期67卷 1160-1169页

作者： NIU QingJing GAO ShuHui ZHU KongYing REN lixia YUAN XiaoYan School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin UniversityTianjin 300350China Analysis and Measurement Center Tianjin UniversityTianjin 300072China

Cryopreservation plays an essential role in biobanking and cell therapy,but the physiological toxicity of traditional cryoprotectants such as glycerol and dimethyl sulfoxide(DMSO)has raised safety issues for biomedical ***,a nonreducing disaccharide that accumulates in desiccation-or cold-tolerant organisms,has been considered as a biocompatible ***,a naturally occurring membrane-active cationic peptide,melittin,was utilized to facilitate membraneimpermeable trehalose entry into cells for effective cell ***(ethylene glycol)and poly(vinyl pyrrolidone)were applied as macromolecular protectants to improve the stabilization of cell *** the optimal protocol,the postthaw recovery of human red blood cells in freezing bags at a hematocrit of~50%could achieve 82.9%with favorable cell morphologies and physiological ***,the cryosurvival of L929 fibroblasts reached 84.3%compared to the conventional method using 10%(v/v)*** short,this work by using trehalose and melittin provides a biocompatible solvent-free approach for long-term cryostorage of cells.

关键词： melittin intracellular trehalose membrane stabilization macromolecular protectants cell cryopreservation

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惯性矩二次变化变截面梁柱几何非线性分析

哈尔滨工业大学学报 2014年第3期46卷 20-25页

作者：孟丽霞陆念力刘士明哈尔滨工业大学机电工程学院哈尔滨150001

为研究考虑剪切变形的变截面梁杆结构几何非线性问题,应用Timoshenko梁理论,采用位移、转角独立插值的方法,获取考虑剪切影响的惯性矩二次变化变截面梁单元的形函数;从严格的虚功增量方程出发,建立同时考虑轴力、剪切、弯曲效应及其耦... 详细信息

为研究考虑剪切变形的变截面梁杆结构几何非线性问题,应用Timoshenko梁理论,采用位移、转角独立插值的方法,获取考虑剪切影响的惯性矩二次变化变截面梁单元的形函数;从严格的虚功增量方程出发,建立同时考虑轴力、剪切、弯曲效应及其耦合项的平面变截面梁柱单元几何非线性增量平衡方程,得到惯性矩二次变化变截面梁单元大位移切线刚度阵;与经典算例进行对比,验证了本文方法的精确性与有效性.

关键词：有限单元法变截面梁虚功增量方程大位移几何非线性

Research on Carbon Emission for Preventive Maintenance of Wind Turbine Gearbox Based on Stochastic Differential Equation

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Energy Engineering 2024年第4期121卷 973-986页

作者： Hongsheng Su lixia Dong Xiaoying Yu Kai Liu School of Automation and Electrical Engineering Lanzhou Jiaotong UniversityLanzhou730070China

Time based maintenance(TBM)and condition based maintenance(CBM)are widely applied in many large wind farms to optimize the maintenance issues of wind turbine gearboxes,however,these maintenance strategies do not take into account environmental benefits during full life cycle such as carbon emissions ***,this article proposes a carbon emissions computing model for preventive maintenance activities of wind turbine gearboxes to solve the *** on the change of the gearbox state during operation and the influence of external random factors on the gearbox state,a stochastic differential equation model(SDE)and corresponding carbon emission model are established,wherein SDE is applied to model the evolution of the device state,whereas carbon emission is used to implement carbon emissions *** simulation results indicate that the proposed preventive maintenance cannot ensure reliable operation of wind turbine gearboxes but reduce carbon emissions during their *** with TBM,CBM minimizes unit carbon emissions without influencing reliable operation,making it an effective maintenance method.

关键词： Stochastic differential equation(SDE) condition-based maintenance(CBM) carbon emissions