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The effect of Levocarnitine on nutritional status and lipid metabolism during long-term maintenance hemodialysis

Journal of Pharmaceutical Analysis 2010年第3期22卷 203-207页

作者： Rong-Guo Fu1,Li Wang1,Jian-Ping zhou2,Feng Ma1,Xiao-Dan liu1,Heng Ge1,Jun Zhang3 1.department of Nephrology 2.department of Pediatrics 3.department of Digestive Internal Medicine,the Second Affiliated Hospital,Medical School of Xi’an Jiaotong university,Xi’an,710004,china department of Nephrology Second Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710004 China department of Pediatrics Second Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710004 China department of Digestive Internal Medicine Second Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710004 China

Objective To investigate the effect of Levocarnitine on lipid metabolism and nutritional status of maintenance hemodialysis(MHD)patients and possible *** A total of 40 MHD patients [mean age(53.5±7.1)years] who underwent normal hemodialysis more than 6 months were randomly classified into two groups,Levocarnitine supplemented group(LS-G)(n=20;Levocarnitine supplementation after each normal hemodialysis session,at a dose of 1.0 g/day by intravenous administration)and control group(C-G)(n=20;normal hemodialysis).Before treatment,one month and three months after treatment we respectively measured or observed the following items,the tolerance to hemodialysis,carnitine level in plasma,C-reactive protein,IL-6,TNF-α,percentage of neutrophil,and some relevant nutritional parameters,such as lipid profile,transferrin,total protein,albumin and prealbumin *** analysis was conducted between the two *** In LS-G three months after treatment,the levels of carnitine,hemoglobin,and prealbumin in plasma were significantly increased(P<0.05),but C-reactive protein,neutrophil percentage,low-density lipoprotein and triglyceride were significantly decreased(P<0.05)in contrast to those in C-G and before ***,total protein,and albumin were elevated in LS-G,with no statistical *** There was a significant improvement of lipid metabolism and nutritional status for the long-term maintenance hemodialysis patients with Levocarnitine *** this improvement is related to the decrease of inflammatory factors.

关键词： inflammatory factors nutritional status maintenance hemodialysis lipid metabolism Levocarnitine

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Probing dark matter particles from evaporating primordial black holes via electron scattering in the CDEX-10 experiment

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Science china(Physics,Mechanics & Astronomy) 2024年第10期67卷 83-91页

作者： Zhenhua Zhang Litao Yang Qian Yue Kejun Kang Yuanjing Li Haipeng An Greeshma C. Jianping Chang Yunhua Chen Jianping Cheng Wenhan Dai Zhi Deng Changhao Fang Xinping Geng Hui Gong Qiuju Guo Tao Guo Xuyuan Guo Li He Shengming He Jinwei Hu Hanxiong Huang Tuchen Huang Lin Jiang S.Karmakar Haubin Li Hanyu Li Jianmin Li Jin Li Qianyun Li Renmingjie Li Xueqian Li Yulan Li Yifan Liang Bin Liao FongKay Lin ShinTed Lin Jiaxuan liu Shukui liu Yandong liu Yu liu Yuanyuan liu Hao Ma Yucai Mao Qiyuan Nie Jinhua Ning Hui Pan Ningchun Qi Jie Ren Xichao Ruan Monoj Kumar Singh Tianxi Sun Changjian Tang Yang Tian Guangfu Wang Junzheng Wang Li Wang Qing Wang Yufeng Wang Yunxiang Wang Henry Tsz-King Wong Shiyong Wu Yucheng Wu Haoyang Xing Rui Xu Yin Xu Tao Xue Yulu Yan Nan Yi Chunxu Yu Haijun Yu Jianfeng Yue Ming Zeng Zhi Zeng Bingtao Zhang Fengshou Zhang Lei Zhang Zhenyu Zhang Jizhong Zhao Kangkang Zhao Minggang Zhao Jifang zhou Zuying zhou Jingjun Zhu CDEX Collaboration Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and department of Engineering Physics Tsinghua UniversityBeijing 100084China department of Physics Tsinghua UniversityBeijing 100084China Institute of Physics Academia SinicaTaipei 11529China NUCTECH Company Beijing 100084China YaLong River Hydropower Development Company Chengdu 610051China College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875China College of Physics Sichuan UniversityChengdu 610065China School of Physics Peking UniversityBeijing 100871China department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413China Sino-French Institute of Nuclear and Technology Sun Yet-sen UniversityZhuhai 519082China School of Physics Nankai UniversityTianjin 300071China department of Physics Banaras Hindu UniversityVaranasi 221005India department of Physics Beijing Normal UniversityBeijing 100875China 不详

Dark matter(DM)is a major constituent of the ***,no definite evidence of DM particles(denoted as“χ”)has been found in DM direct detection(DD)experiments to *** is a novel concept of detectingχfrom evaporating primordial black holes(PBHs).We search forχemitted from PBHs by investigating their interaction with target *** examined PBH masses range from 1×10^(15)to 7×10^(16)g under the current limits of PBH abundance *** 205.4 kg·day data obtained from the CDEX-10 experiment conducted in the china Jinping Underground Laboratory,we exclude theχ-electron(χ-e)elastic-scattering cross sectionσ_(χe)~5×10^(-29)cm^(2)forχwith a mass■keV from our *** the higher radiation background but lower energy threshold(160 eV),CDEX-10 fills a part of the gap in the previous ***(m_(χ),σ_(χe))can be determined in the future,DD experiments are expected to impose strong constraints on fPBHfor large MPBHs.

关键词： CDEX primordial black hole light dark matter particle dark matter-electron scattering high purity germanium detector

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Temperature Dependence of Magnetic Properties of SmCo/FeCo Multilayer Films

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Journal of Materials Science & Technology 2000年第2期16卷 199-200页

作者： Xianghua liu, Ge YAN, Liya CUI and Shaoxiong zhou (National Amorphous & Nanocrystalline Alloy Engineering Research Center, Central Iron & Steel Research Institute, Beliing 100081, china) Wu ZHENG, Ailing WANG and Jinchang CHEN (department of Physics, Cap National Amorphous and Nanocrystalline Alloy Engineering Research Center Central Iron and Steel Research Institute Beijing 100081 China department of Physics Capital Normal University Beijing 100037 China

Sm22Co78/Fe65Co35/Sm22Co78/Fe65Co35 multilayer films were prepared by magnetron sputtering. The temperature dependence of coercivity (Hc), remanence (Mr) and reduced remanence (Mr/Ms) has been measured. The coercivity decreases with increasing of temperature. The remanence decreases with increasing the temperature from 26 to 100℃, and then increases with continuously increasing the temperature from 100 to 150℃. The reduced remanence increases with increasing the temperature.

关键词： Co Cr Temperature Dependence of Magnetic Properties of SmCo/FeCo Multilayer Films

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Reconciled estimation of Antarctic ice sheet mass balance and contribution to global sea level change from 1996 to 2021

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Science china Earth Sciences 2024年第11期67卷 3562-3578页

作者： Rongxing LI Guojun LI Gang HAI Huan XIE Yuan CHENG Wei CHEN Xiangbin CUI Minghu DING Chunchun GAO Tong HAO Changqing KE Chuanjin LI Jin LI Yan liu Jiangjun RAN Jiawen REN Qiang SHEN Yunzhong SHEN Hongling SHI Songyun WANG Zemin WANG Jingang ZHAN Baojun ZHANG Min ZHONG Chunxia zhou Center for Spatial Information Science and Sustainable Development Applications Tongji University College of Surveying and Geo-informatics Tongji University Institute for the Conservation of Cultural Heritage School of Cultural Heritage and Information Management Shanghai University College of Resource Environment and Tourism Hubei University of Arts and Science Polar Research Institute of china State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences College of Geodesy and Geomatics Shandong University of Science and Technology School of geography and Ocean Science Nanjing University Shanghai Astronomical Observatory Chinese Academy of Sciences State Key Laboratory of Remote Sensing Science Faculty of Geographical Science Beijing Normal University department of Earth and Space Sciences Southern University of Science and Technology State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and Resources Chinese Academy of Sciences State Key Laboratory of Geodesy and Earth's Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of Sciences Center for Space Research University of Texas at Austin Chinese Antarctic Center of Surveying and Mapping Wuhan University School of Geospatial Engineering and Science Sun Yat-sen University

The Antarctic Ice Sheet（AIS） has been losing ice mass and contributing to global sea level rise（GSLR）. Given its mass that is enough to cause ～58 m of GSLR, accurate estimation of mass balance trend is critical for AIS mass loss monitoring and sea level rise forecasting. Here, we present an improved approach to reconciled solutions of mass balance in AIS and its regions from multiple contributing solutions using the input-out, altimetric, and gravimetric methods. In comparison to previous methods, such as IMBIE 2018, this approach utilizes an adaptive data aggregation window to handle the heterogeneity of the contributing solutions, including the number of solutions, temporal distributions, uncertainties, and estimation techniques. We improved the regression-based method by using a two-step procedure that establishes ensembled solutions within each method（input-output, altimetry, or gravimetry） and then estimates the method-independent reconciled solutions. For the first time, 16contributing solutions from 8 Chinese institutions are used to estimate the reconciled mass balance of AIS and its regions from1996 to 2021. Our results show that AIS has lost a total ice mass of ～3213±253 Gt during the period, an equivalent of～8.9±0.7 mm of GSLR. There is a sustained mass loss acceleration since 2006, from 88.1±3.6 Gt yr-1during 1996–2005 to 130.7 ±8.4 Gt yr-1during 2006–2013 and further to 157.0±9.0 Gt yr-1during 2014–2021. The mass loss signal in the West Antarctica and Antarctic Peninsula is dominant and clearly presented in the reconciled estimation and contributing solutions, regardless of estimation methods used and fluctuation of surface mass balance. Uncertainty and challenges remain in mass balance estimation in East Antarctica. This reconciled estimation approach can be extended and applied for improved mass balance estimation in the Greenland Ice Sheet and mountain glacier regions.

关键词： Antarctic Ice Sheet Ice mass loss acceleration Sea level rise Reconciled estimation

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软-硬互层岩体节理峰前循环剪切疲劳损伤机理研究

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岩土工程学报 2024年第1期46卷 90-100页

作者：许彬刘新荣周小涵韩亚峰刘俊谢应坤邓志云重庆交通大学水利水运工程教育部重点实验室重庆400074 重庆大学土木工程学院重庆400045 中国建筑第二工程局有限公司北京100160 重庆川东南工程勘察设计院有限公司重庆400038 清华大学水利系北京100084

三峡库区频发微小地震下岩体节理循环剪切疲劳损伤对边坡动力稳定性具有重要影响。通过室内峰前循环剪切试验和PFC2D细观数值计算,研究了考虑一阶起伏角、含水率、剪切速率、剪切幅度、法向应力及循环剪切次数影响的软-硬互层岩体节理... 详细信息

三峡库区频发微小地震下岩体节理循环剪切疲劳损伤对边坡动力稳定性具有重要影响。通过室内峰前循环剪切试验和PFC2D细观数值计算,研究了考虑一阶起伏角、含水率、剪切速率、剪切幅度、法向应力及循环剪切次数影响的软-硬互层岩体节理宏细观疲劳损伤机理。研究表明:①岩体节理剪切应力-剪切位移曲线历经初始非线性压剪变形、近似线弹性压剪变形、循环剪切疲劳损伤变形、应力缓升压剪变形、应力陡升压剪变形及应力脆性跌落压剪变形六个演化阶段。②岩体节理峰值(残余)剪切强度和疲劳剪切(法向)位移在相同一阶起伏角、含水率、剪切速率、剪切幅度或法向应力下随循环剪切次增多而分别降低和增大;且其在相同循环剪切次数下随一阶起伏角或法向应力变大而分别增大和降低,而随含水率、剪切速率或剪切幅度变大则分别降低和增大。③宏细观结果总体上吻合较好,且岩体节理细观剪切疲劳损伤裂纹数量随剪切位移变化呈前期微增-陡增、中期缓增及后期陡增-缓增-陡增的发展特征,而其随循环剪切次数变化则呈前期陡增和后期缓增的发展特征。④岩体节理宏细观剪切疲劳损伤典型演化过程可概述为压密-起裂破坏、循环错动-贯通破坏及分离-啃断破坏3个渐进性发展阶段,且宏细观剪切疲劳损伤裂纹近似呈“倒U形”密集分布于岩体节理附近。

关键词：软-硬互层岩体节理峰前循环剪切试验 PFC2D细观数值计算演化过程疲劳损伤机理

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Genome assembly of autotetraploid Actinidia arguta highlights adaptive evolution and enables dissection of important economic traits

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Plant Communications 2024年第6期5卷 173-192页

作者： Xue-Mei Lu Xiao-Fen Yu Guo-Qiang Li Ming-Hao Qu Huan Wang Chuang liu Yu-Ping Man Xiao-Han Jiang Mu-Zi Li Jian Wang Qi-Qi Chen Rui Lei Cheng-Cheng Zhao Yun-Qiu zhou Zheng-Wang Jiang Zuo-zhou Li Shang Zheng Chang Dong Bai-Lin Wang Yan-Xiang Sun Hui-Qin Zhang Jie-Wei Li Quan-Hui Mo Ying Zhang Xin Lou Hai-Xu Peng Ya-Ting Yi He-Xin Wang Xiu-Jun Zhang Yi-Bo Wang Dan Wang Li Li Qiong Zhang Wen-Xia Wang Yongbo liu Lei Gao Jin-Hu Wu Yan-Chang Wang CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Wuhan Botanical GardenChinese Academy of SciencesWuhanHubeiChina Key Laboratory of Western china’s Environmental Systems(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhouGansuChina College of Life Sciences University of Chinese Academy of SciencesBeijingChina Wuhan Frasergen Bioinformatics Co. LtdWuhanHubeiChina Institute of Soil and Fertilizer Anhui Academy of Agricultural SciencesHefeiChina College of Agricultural Sciences Xichang UniversityXichangSichuanChina department of Horticulture Heilongjiang Academy of Agricultural SciencesHarbinHeilongjiangChina College of Life Sciences Langfang Normal UniversityLangfangHebeiChina Institute of Horticulture Zhejiang Academy of Agricultural SciencesHangzhouZhejiangChina Guangxi Institute of Botany Chinese Academy of SciencesGuilinGuangxiChina Xi’an Botanical Garden of Shaanxi Province Institute of Botany of Shaanxi ProvinceXi’anShaanxiChina Institute of Modern Agricultural Research Dalian UniversityDalianLiaoningChina Bioinformatics Center College of Plant Science and TechnologyBeijing University of AgricultureBeijingChina College of Agriculture Eastern Liaoning UniversityDandongLiaoningChina Dalian Institute of Chemical Physics Chinese Academy of SciencesDalianLiaoningChina State Environmental Protection Key Laboratory of Regional Eco-process and Function Assessment Chinese Research Academy of Environmental SciencesBeijingChina Hubei Hongshan Laboratory WuhanHubeiChina The New Zealand Institute for Plant and Food Research Limited AucklandNew Zealand

Actinidia arguta,the most widely distributed Actinidia species and the second cultivated species in the genus,can be distinguished from the currently cultivated Actinidia chinensis on the basis of its small and smooth fruit,rapid softening,and excellent cold *** evolution of tetraploid Actinidia species and the genetic basis of their important agronomic traits are still ***,we generated a chromosome-scale genome assembly of an autotetraploid male *** *** genome assembly was 2.77 Gb in length with a contig N50 of 9.97 Mb and was anchored onto 116 *** and clustering of 101 geographically representative accessions showed that they could be divided into two geographic groups,southern and Northern,which first diverged 12.9 million years *** underwent two prominent expansions and one demographic bottleneck from the midPleistocene climate transition to the late *** genomics studies using paleoclimate data enabled us to discern the evolution of the species’adaptation to different historical *** genes(AaCEL1,AaPME1,and AaDOF1)related to flesh softening were identified by multi-omics analysis,and their ability to accelerate flesh softening was verified through transient expression assays.A set of genes that characteristically regulate sexual dimorphism located on the sex chromosome(Chr3)or autosomal chromosomes showed biased expression during stamen or carpel *** chromosome-level assembly of the autotetraploid *** genome and the genes related to important agronomic traits will facilitate future functional genomics research and improvement of ***.

关键词： kiwiberry dioecism adaptive evolution paleoclimate GEA rapid softening

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共同学习:促进学生互动的教学策略

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外国教育研究 2003年第10期30卷 9-13页

作者：刘晓明周楚黄丽娜东北师范大学教育科学学院吉林长春130024 华东师范大学心理学系上海200062 解放军军需大学政治理论研究室吉林长春13000

共同学习是近20多年来发展起来的一种新型的教学策略,包含六个基本要素:正相互依赖、个人责任感、混合编组、教授合作技巧、检查小组交互行为和多能力任务,主要方法是小组协作教学。共同学习既考虑到了课堂教学中的师生互动,更重视学生... 详细信息

共同学习是近20多年来发展起来的一种新型的教学策略,包含六个基本要素:正相互依赖、个人责任感、混合编组、教授合作技巧、检查小组交互行为和多能力任务,主要方法是小组协作教学。共同学习既考虑到了课堂教学中的师生互动,更重视学生之间的互动学习,充分看到了学生在课堂教学中的主体性与主动性。

关键词：共同学习学生互动教学策略小班化教学课堂教学合作技巧

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Realization of nonlinear interferometer using the four wave mixing in hot rubidium vapor

Realization of nonlinear interferometer using the four wave ...

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第十五届全国量子光学学术报告会

作者： Jietai Jing 1,2,Cunjin liu 1,2,Jia Kong 1,2,Florian Hudelist 1,2,Zhifan zhou 1,2 Hailong Wang 1,2,Z.Y.Ou 1,2,Weiping Zhang 1,2 (1.State Key Lab of Precision Spectroscopy,East china normal university 2.Quantum Institute for Light and Atoms,department of Physics,East china normal university)

＜正＞Optical interferometer is the basis for precision *** this paper,we report on an experiment in which we construct a nonlinear interferometer with four wave mixing amplifiers acting as beam splitters to split and...

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土壤溶质运移参数估计图解方法

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土壤学报 2004年第5期41卷 715-720页

作者：刘春平叶乐安邵明安周学军湖南师范大学资源与环境科学学院长沙410006 温州师范学院浙江温州325027 中国科学院水利部水土保持研究所陕西杨凌712100

基于土壤中溶质运移的对流弥散方程 (CDE)提出了溶质运移参数估计的图解方法。根据土柱溶质运移“穿透曲线”(BTC)数据计算通量浓度随时间变化 (dc/dt)。应用绘图软件 ,例如MicrosoftExcel,绘制出t1 5dc/dt和dc/dt相对于时间的变化... 详细信息

基于土壤中溶质运移的对流弥散方程 (CDE)提出了溶质运移参数估计的图解方法。根据土柱溶质运移“穿透曲线”(BTC)数据计算通量浓度随时间变化 (dc/dt)。应用绘图软件 ,例如MicrosoftExcel,绘制出t1 5dc/dt和dc/dt相对于时间的变化曲线。这两条曲线都是单峰曲线 ,并被用于估计CDE中延迟因子(R)和弥散系数 (D0 )。设计算例和穿透实验数据被用于校正图解法估计参数的精度和稳定性。参数估计的稳定性由估计参数对它们平均值的标准差评价 ;参数的估计精度与CXTFIT法和等斜率法比较。结果表明图解法具有较高的精度和较好的稳定性 ,特别是对于运移参数R的估值。图解法是一个确定性方法 ,它具备确定性方法中估计参数唯一性特点 ,克服了统计方法中需要给定参数初值的缺点。因此 ,这个方法是土壤溶质运移参数估计的可选方法之一。

关键词：土壤溶质运移参数估计图解方法营养物质

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Al-Zn-Mg-Cu-Li合金时效过程微结构演化的小角x射线散射研究

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物理学报 2004年第4期53卷 1251-1254页

作者：赵辉杜志伟周铁涛刘培英董宝中陈昌麒中国科学院高能物理研究所同步辐射实验室北京航空航天大学材料科学和工程学院北京100083

应用小角x射线散射技术分析了Al_Zn_Mg_Cu_Li合金在 13 0 ,150和 160℃温度时效 2 4h析出粒子的微结构参数的变化情况 .粒子的半径随着时效温度的增高而增加 ,它的比内表面积和体积百分数随着时效温度的增高而减小 .对Porod曲线q3J(q) ... 详细信息

应用小角x射线散射技术分析了Al_Zn_Mg_Cu_Li合金在 13 0 ,150和 160℃温度时效 2 4h析出粒子的微结构参数的变化情况 .粒子的半径随着时效温度的增高而增加 ,它的比内表面积和体积百分数随着时效温度的增高而减小 .对Porod曲线q3J(q) q2 的分析表明。

关键词：小角X射线散射技术铝-锌-镁-锂合金结构参数时效温度析出粒子 Porod曲线析出粒子

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