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C-HMAX: Artificial Cognitive Model Inspired by the Color Vision Mechanism of the Human Brain

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Tsinghua Science and Technology 2013年第1期18卷 51-56页

作者： Bo Yang lipu Zhou Zhidong Deng the State Key Laboratory of Intelligent Technology and Systems Tsinghua National Laboratory for Information Science and TechnologyDepartment of Computer Science and TechnologyTsinghua University

Artificial cognitive models and computational neuroscience methods have garnered great interest from both neurologist and leading analysts in recent years. Among the cognitive models, HMAX has been widely used in computer vision systems for its robustness shape and texture features inspired by the ventral stream of the human brain. This work presents a Color-HMAX （C-HMAX） model based on the HMAX model which imitates the color vision mechanism of the human brain that the HMAX model does not include. C-HMAX is then applied to the German Traffic Sign Recognition Benchmark （GTSRB） which has 43 categories and 51 840 sample traffic signs with an accuracy of 98.41%, higher than most other models including linear discriminant analysis and multi-scale convoiutional neural network.

关键词： artificial cognitive model machine learning traffic sign recognition

Propagation of local spatial solitons in power-law nonlinear PT-symmetric potentials based on finite difference

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Communications in Theoretical Physics 2021年第12期73卷 14-24页

作者： Hao Ji Yinghong Xu Chaoqing Dai lipu Zhang Department of Mathematics Zhejiang Sci-Tech UniversityHangzhou310018China Department of Physics Zhejiang A&F UniversityHangzhou311300China College of Media Engineering Communication University of ZhejiangHangzhou310018China

We consider the(2+1)-dimensional nonlinear Schrodinger equation with power-law nonlinearity under the parity-time-symmetry potential by using the Crank-Nicolson alternating direction implicit difference scheme,which can also be used to solve general boundary problems under the premise of ensuring *** use linear Fourier analysis to verify the unconditional stability of the *** demonstrate the effectiveness of the scheme,we compare the numerical results with the exact soliton ***,by using the scheme,we test the stability of the solitons under the small environmental disturbances.

关键词： nonlinear Schrodinger equation localized spatial solitons PT-symmetric potential ADI difference scheme stability

The Most Complete Sequence of Telychian Graptolite Zones in the World

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Acta Geologica Sinica(English Edition) 2000年第2期74卷 126-131页

作者： FU lipu ZHANG Zifu GENG Liangyu Xi'an Institute of Geology and Mineral Resources Xi'an 710054 Shaanxi Nanjing Institute of Geology and Palaeontology Chinese Academy of Sciences Nanjing 210008 Jiangsu

This paper divides the Telychian into 7 graptolite zones, 12 subzones and 4 chitinoans in the Ziyang region, China. The zones and subzones of England are almost totally suitable for the case of Ziyang in China, though they are 10000 km apart. All the above-mentioned biozones are found only in a unitary continuous section in Ziyang. It has been proved that the Ziyang section is the one with the most complete sequence of Telychian graptolite biozones in the world.

关键词： high-resolution graptolite zone chitinozoan Telychian

Combination of steam-enhanced extraction and electrical resistance heating for efficient remediation of perchloroethylene-contaminated soil:Coupling merits and energy consumption

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Frontiers of Environmental Science & Engineering 2022年第11期16卷 249-260页

作者： Rui Yue Zhikang Chen Liujun Liu lipu Yin Yicheng Qiu Xianhui Wang Zhicheng Wang Xuhui Mao School of Resource and Environmental Sciences Wuhan UniversityWuhan 430079China China State Science Dingshi Environmental Engineering Company Beijing 100020China

In situ thermal desorption(ISTD)technology effectively remediates soil contaminated by dense nonaqueous phase liquids(DNAPLs).However,more efforts are required to minimize the energy consumption of ISTD *** study developed a laboratory-scale experimental device to explore the coupling merits of two traditional desorption technologies:steam-enhanced extraction(SEE)and electrical resistance heating(ERH).The results showed that injecting high-density steam(>1 g/min)into loam or clay with relatively high moisture content(>13.3%)could fracture the soil matrix and lead to the occurrence of the preferential flow of *** ERH alone,the electrical resistance and soil moisture loss were critical factors influencing heating *** ERH and SEE were combined,preheating soil by ERH could increase soil permeability,effectively alleviating the problem of preferential flow of ***,steam injection heated the soil and provided moisture for maintaining soil electrical conductivity,thereby ensuring power stability in the ERH *** with ERH alone(8 V/cm)and SEE alone(1 g/min steam),the energy consumption of combined method in remediating perchloroethylene-contaminated soil was reduced by 39.3%and 52.9%,*** findings indicate that the combined method is more favorable than ERH or SEE alone for remediating DNAPL-contaminated subsurfaces when considering ISTD technology.

关键词： Steam-enhanced extraction Electrical resistance heating Dense nonaqueous phase liquid Soil remediation Energy consumption

Efficient Removal of Lead from Washing Effluent of Lead-contaminated Soil with Garlic Peel

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Chemical Research in Chinese Universities 2018年第6期34卷 1020-1027页

作者： CHEN Xing YIN lipu ZHOU Hongyu LIU Junyou LI Xiaohui AI Xianbin HUANG Kai School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 P. R. China Beijing Keda Advanced Teehnology Company Beijing 100083 P. R. China Institute of Bioresouree Jiangxi Aeademy of Sciences Nanehang 330096 R R. China

Wastewater produced from the soil washing process contains heavy metals, which limits its reuse for washing. So it is necessary to develop an efficient and economical way to recycle it, and this study presented a biosorption method to realize this goal. A typical soil sample contaminated by lead was taken from the real field near a lead smelting factory, used for the toxic metals extraction with dilute citric acid. A leach liquor was obtained with lead ions at the level of 12.35 mg/L, Cd 1.2 mg/L, Cu 1.5 mg/L, Zn 2.6 mg/L, as well as the coexisting anions, such as sulphate, silicate, chloride at the concentration of several hundred miligram per liter. The garlic peel was modified by a simple chemical saponification process and used as the biosorbent for toxic metal removal. Firstly, the adsorp- tion behavior of lead ions on the saponified garlic peel was systematically investigated using the synthetic solutions, and then the adsorption mechanisms were explored by detailed experhnents combining with the thermodynamic calculation reuslts of the aqueous system of Pb（II）-citrate-H2O. It was found that in artificial solution containing 0.01 mol/L citrate, the maximum adsorption capacity of 261.0 mg/g was reached at pH near 3.0, and also at this very pH value the Pb^2＋ and Pb（H2Cit）＋ were the dominant lead species, which are favorable for adsorption due to its easier approaching to the --COO^- ligands in the saponified garlic peel partilces via charge attraction, and the appearance of Pb（HCit）; and Pb（Cit）- at pH above 3.0 inhibits the adsorption. Secondly, the real leach liquor was used for adsorption tests, and twice adsorption under the optimal conditons would decrease the residual concentrations of Pb, Cd, Cu and Zn to zero. After elution by using 0.1 mol/L nitric acid, the adsorbed metals can be recovered and garlic peel can be reused for at least 10 cycles effectively. This study presents a prospective biosorption method for economical and efficient removal of the l

关键词： Lead Biosorpfion Garlic peel Citrate Soil washing wastewater

Regulations of m^(6)A methylation on tomato fruit chilling injury

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Horticultural Plant Journal 2021年第5期7卷 434-442页

作者： Chunmei Bai Minghuan Fang Baiqiang Zhai Lili Ma Anzhen Fu lipu Gao Xiaohong Kou Demei Meng Qing Wang Shufang Zheng Jinhua Zuo State Key Laboratory of Food Nutrition and Safety College of Food Science and EngineeringTianjin University of Science&TechnologyTianjin 300457China Key Laboratory of Vegetable Postharvest Processing Ministry of AgricultureBeijing Key Laboratory of Fruit and Vegetable Storage and ProcessingKey Laboratory of Biology and Genetic Improvement of Horticultural Crops(North China)of Ministry of AgricultureKey Laboratory of Urban Agriculture(North)of Ministry of AgricultureBeijing Vegetable Research CenterBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Key Laboratory of Marine Chemistry Theory and Technology Ministry of EducationOcean University of ChinaQingdao 266100China Henan Railway Food Safety Management Engineering Technology Research Center Zhengzhou 451460China College of Food Science and Technology Hebei Agricultural UniversityBaoding 071001China School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China

Tomato fruit are sensitive to chilling injury(CI)during cold *** factors have been discovered to be involved in chilling injury of tomato *** hormones play an important regulatory role,however,the relationship between chilling injury and N6-methyladenosine(m^(6)A)methylation of transcripts in plant hormone pathways has not been reported *** order to clarify the complex regulatory mechanism of m^(6)A methylation on chilling injury in tomato fruit,Nanopore direct RNA sequencing was employed.A large number of enzymes and transcription factors were found to be involved in the regulation process of fruit chilling injury,which were associated with plant hormone,such as 1-aminocyclopropane 1-carboxylate synthase(ACS),aspartate aminotransferase(AST),auxin response factor(ARF2),ethylene response factor 2(ERF2),gibberellin 20-oxidase-3(GA20ox)and jasmonic acid(JA).By conjoint analysis of the differential expression transcripts related to chilling injury andm^(6)Amethylation differential expression transcripts 41 differential expression transcripts were identified involved in chilling injury including 1-aminocyclopropane-1-carboxylate oxidase(ACO)and pectinesterase(PE)were down-regulated and heat shock cognate 70 kD protein 2(cpHSC70),HSP70-binding protein(HspBP)and salicylic acid-binding protein 2(SABP2)were *** results will provide a deeper understanding for chilling injury regulatory mechanism and post-harvest cold storage of tomato fruit.

关键词： m^(6)A methylation Chilling injury Plant hormone Nanopore direct RNA sequencing Tomato fruit

A homogenized approach to classify advanced gastric cancer patients with limited and adequate number of pathologically examined lymph nodes

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Cancer Communications 2019年第1期39卷 303-313页

作者： Sharvesh Raj Seeruttun lipu Xu Fangwei Wang Xiaodong Yi Cheng Fang Zhimin Liu Wei Wang Zhiwei Zhou Department of Gastric Surgery State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer Center651 Dongfeng Road EastGuangzhou 510060GuangdongP.R.China Department of Surgical Oncology Affiliated Lu’an Hospital of Anhui Medical UniversityLu’an 237005AnhuiP.R.China

Background:The prognosis of gastric cancer patients with a limited number of pathologically examined lymph nodes(eLN,<16)is dismal compared to those with adequately eLN(≥16),yet they are still classified within the same subgroups using the American Joint Committee on Cancer(AJCC)staging *** aimed at formulating an easy-to-adopt and clinically reliable stratification approach to homogenize the classification for these two categories of ***:Patients staged according to the 8th AJCC pathological nodal(N)and tumor-node-metastasis(TNM)clas-sification were stratified into a Limited and Adequate eLN cohort based on their number of pathologically examined *** statistical differences between the 5-year overall survival(OS)rates of both cohorts were determined and based on which,patients from the Limited eLN cohort were re-classified to a proposed modified nodal(N′)and TNM(TN′M)classification,by matching their survival rates with those of the Adequate eLN *** prognostic perfor-mance of the N′and TN′M classification was then compared to a formulated lymph-node-ratio-based nodal classifica-tion,in addition to the 8th AJCC N and TNM ***:Significant heterogeneous differences in 5-year OS between patients from the Limited and Adequate eLN cohort of the same nodal subgroups were identified(all P<0.001).However,no significant differences in 5-year OS were observed between the subgroups N0,N1,N2,and N3a of the Limited eLN cohort when compared with N1,N2,N3a,and N3b from the Adequate eLN cohort,respectively(P=0.853,0.476,0.114,and 0.230,respectively).A novel approach was formulated in which only patients from the Limited eLN cohort were re-classified to one higher nodal subgroup,denoted as the N′*** re-classification demonstrated superior stratifying and prognostic ability as compared to the 8th AJCC N and lymph-node-ratio classification(Akaike information criterion values[AIC]:12,276 vs.12,358 vs.12,283,respectively).Th

关键词： Advanced gastric cancer Limited lymph nodes Adequate lymph nodes R0 gastrectomy AJCC Eighth edition Modified classification Akaike information criterion Lymph node ratio Prognosis

A two-year longitudinal observational study of the peripapillary microvasculature in pediatric type 1 diabetes mellitus patients without visual impairment or diabetic retinopathy

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Advances in Ophthalmology Practice and Research 2024年第1期4卷 15-22页

作者： lipu Cui Chenhao Yang Haidong Zou Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Ophthalmology Children's Hospital of Fudan UniversityShanghaiChina Shanghai Eye Diseases Prevention&Treatment Center Shanghai Eye HospitalShanghaiChina Shanghai Key Laboratory of Fundus Diseases ShanghaiChina National Clinical Research Center for Eye Diseases ShanghaiChina Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases ShanghaiChina

Dear Editor,Approximately 5 million children worldwide have type 1 diabetes mellitus(T1DM),and this number increases by 80000 people per year.1 Diabetic children have a younger age of onset and a longer survival period than adult DM patients;almost all of them develop diabetic reti-nopathy(DR)by the time their DM duration reaches 20 *** is the most common microvascular complication in DM patients and the lead-ing cause of blindness and vision loss in working-age people.

关键词： patients diabetic mellitus

De novo sequencing and comparative analysis of three red algal species of Family Solieriaceae to discover putative genes associated with carrageenan biosysthesis

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Acta Oceanologica Sinica 2014年第2期33卷 45-53页

作者： SONG lipu WU Shuangxiu SUN Jing WANG Liang LIU Tao CHI Shan LIU Cui LI Xingang YIN Jinlong WANG Xumin YU Jun CAS Key Laboratory of Genome Sciences and Information Beijing Key Laboratory of Genome and Precision Medicine TechnologiesBeijing Institute of GenomicsChinese Academy of Sciences Beijing Key Laboratory of Functional Genomics for Dao-di Herbs Beijing Institute of GenomicsChinese Academy of Sciences University of Chinese Academy of Sciences College of Marine Life Science Ocean University of China

Betaphycus gelatinus, Kappaphycus alvarezii and Eucheuma denticulatum of Family Solieriaceae, Order Gi-gartinales, Class Rhodophyceae are three important carrageenan-producing red algal species, which pro-duce different types of carrageenans, beta （β）-carrageenan, kappa （κ）-carrageenan and iota （ι）-carrageenan. So far the carrageenan biosynthesis pathway is not fully understood and few information is about the So-lieriaceae genome and transcriptome sequence. Here, we performed the de novo transcriptome sequencing, assembly, functional annotation and comparative analysis of these three commercial-valuable species using an Illumina short-sequencing platform Hiseq 2000 and bioinformatic software. Furthermore, we compared the different expression of some unigenes involved in some pathways relevant to carrageenan biosynthe-sis. We finally found 861 different expressed KEGG orthologs which contained a glycolysis/gluconeogenesis pathway （21 orthologs）, carbon fixation in photosynthetic organisms （16 orthologs）, galactose metabolism （5 orthologs）, and fructose and mannose metabolism （9 orthologs） which are parts of the carbohydrate me-tabolism. We also found 8 different expressed KEGG orthologs for sulfur metabolism which might be impor-tantly related to biosynthesis of different types of carrageenans. The results presented in this study provided valuable resources for functional genomics annotation and investigation of mechanisms underlying the biosynthesis of carrageenan in Family Solieriaceae.

关键词： Betaphycus gelatinus Kappaphycus alvarezii Eucheuma denticulatum Solieriaceae de novo transcriptome sequencing carrageenan