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Stereotactic body radiation therapy versus radiofrequency ablation in patients with small hepatocellular carcinoma:a systematic review and meta-analysis

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Hepatobiliary Surgery and Nutrition 2021年第5期10卷 623-630,I0008页

作者： Jiawei Hong linping Cao Haiyang Xie yuanxing Liu Jun yu Shusen Zheng Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryFirst Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouChina Key Lab of Combined Multi-Organ Transplantation Ministry of Public HealthHangzhouChina The Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Zhejiang UniversityHangzhouChina

Background:This study aimed to compare the clinical outcomes and toxicity between small hepatocellular carcinoma(HCC)patients treated with stereotactic body radiation therapy(SBRT)and those treated with radiofrequency ablation(RFA).Methods:We searched databases for relevant clinical *** primary outcomes of interest were overall survival(OS)at 1 and 2 years,freedom from local progression(FFLP)rate at 2 years,and ***:Five cohorts from 5 retrospective studies and 4,814 patients with HCC were *** OS at 2 years was significantly lower for SBRT than for RFA[odds ratio(OR):0.63;95%confidence interval(CI):0.51-0.79;P<0.0001],but the pooled FFLP rate at 2 years was higher for SBRT than for RFA(OR:1.66;95%CI:1.05-2.61;P=0.03).In addition,there was no significant difference in the local and liver toxicities of the two *** contradictory conclusion between the OS and FFLP outcome may be attributed to the difference in radiological dose and location,but there were no uniform criteria to illustrate the radiological dose and location in the included ***:SBRT had a higher local control ratio but poorer prognosis than RFA in patients with small *** local toxicity was comparable in both *** trials should be designed with uniform standards for SBRT and RFA treatments.

关键词： Hepatocellular carcinoma(HCC) stereotactic body radiation therapy(SBRT) radiofrequency ablation(RFA) meta-analysis

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DynamicMechanical and Chemorheology Analysis for the Blended Epoxy System with Polyurethane Modified Resin

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Journal of Renewable Materials 2022年第4期10卷 1081-1095页

作者： Xue Xin yu Rong linping Su Zhengmei Qiu Chenjun Yang Ming Liang Ping Ji Guoqiang Zhong Zhanyong Yao School of Qilu Transportation Shandong UniversityJinan250002China Shandong Hi-Speed Group Co. Ltd.Jinan250014China Shandong Provincial Communications Planning and Design Institute Group Co. Ltd.Jinan250031China

As the important matrix material,epoxy resin has been widely used in the composites for various *** account of the poor toughness of epoxy resin limiting their suitability for advanced applications,considerable interests have been conducted to modify the epoxy resin to meet the engineering *** this study,the bio-based polyurethane(PU)modified resin was adopted to modify the pure bisphenol-A epoxy by blending method with various *** to illuminate the curing behavior,mechanical and thermal properties,the blended epoxy systems were characterized by viscosity-time analysis,dynamic mechanical analysis(DMA)at different frequencies and temperatures,mechanical tensile test,thermogravimetric analysis(TGA)and Fourier transform infrared(FT-IR)*** results indicated that the introduction of PU modified epoxy was found to significantly inhibit the viscosity growth rates especially when the content of PU modified epoxy resin is higher than 60%.Notwithstanding the dynamic modulus and T_(g)reduced with the increment of PU modified epoxy,remarkable increment on the elongation at break was found and the flexibility was greatly promoted with the introduction of PU modified *** proportion of PU modified epoxy in the blends should be put balance considerations to obtain optimal mechanical *** results and FTIR spectrum demonstrated that the addition of PU modified epoxy did not change the thermal decomposition mechanism and chemical reaction mechanism,but the addition of PU modified epoxy inhibits the curing reaction of epoxy resin by measured and calculated the damping temperature domainT from 35.7℃ to 48.9℃.

关键词： Dynamic mechanical property chemorheology analysis blended epoxy system polyurethane modified resin

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Physical-biogeochemical interactions and potential effects on phytoplankton and Ulva prolifera in the coastal waters off Qingdao(Yellow Sea, China)

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Acta Oceanologica Sinica 2019年第2期38卷 11-23页

作者： Qinsheng Wei Baodong Wang Qingzhen Yao Zhigang yu Mingzhu Fu Junchuan Sun Bochao Xu linping Xie Ming Xin First Institute of Oceanography Ministry of Natural Resources Laboratory for Marine Ecology and Environmental Science Pilot National Laboratory for Marine Science and Technology (Qingdao) Key Laboratory of Marine Chemistry Theory and Technology of Ministry of Education Ocean University of China

In recent years, the spectacular massive green tide of Ulva prolifera has become a recurrent phenomenon appearing every summer in the coastal waters off Qingdao(Yellow Sea, China), attracting the attention of scientists and local government. Based on multidisciplinary data collected during summer and winter, this study focuses on the hydrological characteristics and regional biogeochemical processes in coastal waters off *** results show that the boundary of the Yellow Sea Cold Water Mass(YSCWM) can reach the Qingdao coastal region in summer and is locally raised to the upper layers to form coastal upwelling beyond tidal mixing and favorable wind. The regional summer upwelling off the Qingdao coast effectively enriches the nutrient concentrations in the upper water column and thus promotes growth of phytoplankton but reduces the dissolved oxygen(DO) concentration and pH value in the bottom. The regional summer upwelling off Qingdao coast may facilitate the growth and regional blooming of the U. prolifera that migrate to this region with the southerly ***, the effects of the front on the aggregation of U. prolifera may be significant. In winter, the Yellow Sea Warm Current(YSWC) extends and spreads along the offshore region off the Subei Shoal towards the Qingdao coastal sea. This tongue-shaped warm water meets the cold coastal water off Qingdao, which leads to the formation of a physical front. As a consequence, remarkable fronts of nutrient and chlorophyll a(Chl a) also form between the shoreward warm water and the cold coastal water. This study increases the understanding of the interactions between the regional physical, chemical, and biological processes off the Qingdao coast.

关键词： biogeochemical process upwelling front Ulva prolifera Qingdao coast southern Yellow Sea

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电解二氧化锰行业“前消后用”固废资源化应用发展策略

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中国锰业 2023年第2期41卷 7-12页

作者：全军蓝晗兮黄先碧吴勇喻林萍陈奇志王智青黄中伟广西来宾市科技开发中心来宾广西546100 广西来宾市科学技术情报研究所来宾广西546138 长沙理工大学化学化工学院长沙湖南410114 广西汇元锰业有限责任公司来宾广西546138

基于电解二氧化锰(EMD)生产工艺特征,提出从前端消纳蔗渣造纸白泥到末端锰渣进一步资源化利用的“前消后用”固废高值化应用策略。在EMD生产制液工序中以蔗渣造纸白泥替代石灰,并对蔗渣造纸白泥引入的杂质进行针对性地去除,从而避免影... 详细信息

基于电解二氧化锰(EMD)生产工艺特征,提出从前端消纳蔗渣造纸白泥到末端锰渣进一步资源化利用的“前消后用”固废高值化应用策略。在EMD生产制液工序中以蔗渣造纸白泥替代石灰,并对蔗渣造纸白泥引入的杂质进行针对性地去除,从而避免影响硫酸锰溶液的净化流程以及EMD产品的品质,在消纳了固废蔗渣造纸白泥的同时也较显著地节约了EMD生产成本。对EMD工业中产生的锰渣固废进行资源化利用,获得水泥混合材添加剂和磷酸锰铁锂基正极材料等新产品,有效地解决蔗渣造纸企业和电解二氧化锰企业固废大量堆积的困扰,同时对其他行业推进固废资源的规模化、高值化利用具有参考意义。

关键词：蔗渣白泥电解二氧化锰锰渣固废资源化利用

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纸质杆系结构的力学分析与实践研究

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山西建筑 2016年第31期42卷 56-58页

作者：汪亚伟牛海英于林平苑可可朱宜超吴宏桥王福平大连海洋大学海洋与土木工程学院辽宁大连116023

介绍了纸质杆系结构设计的基本思路,总结了结构强度与刚度分析的基本方法,根据结构破坏形式及其力学机理,给出了纸质杆系结构设计的建议,有利于培养土木类专业学生的力学分析能力和结构设计能力。

关键词：纸质杆件结构设计应力承载力

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电解二氧化锰电极材料应用与研究进展

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中国锰业 2022年第3期40卷 1-7页

作者：万维华许梓奕陈奇志窦肖艺吴勇贺跃辉喻林萍广西汇元锰业有限责任公司广西来宾546138 长沙理工大学化学化工学院湖南长沙410114 中南大学粉末冶金国家重点实验室湖南长沙410017

电解二氧化锰(EMD)是电池行业非常重要的化工原料。在电解二氧化锰工业中,电解阳极和阴极材料的选择是EMD生产工艺进行优化升级的前提,直接影响着EMD产品的品质和企业的经济效益。在电池市场迅速发展以及国家提出“双碳目标”的大环境下... 详细信息

电解二氧化锰(EMD)是电池行业非常重要的化工原料。在电解二氧化锰工业中,电解阳极和阴极材料的选择是EMD生产工艺进行优化升级的前提,直接影响着EMD产品的品质和企业的经济效益。在电池市场迅速发展以及国家提出“双碳目标”的大环境下,优化核心生产部件及创新生产工艺是我国EMD行业在世界舞台上引领产业升级的必经之路。传统的电极材料已无法进一步满足EMD企业实现提质节能生产的发展需求,亟待新型关键材料的研究与突破,继而有力地支撑EMD行业进行技术升级。综述了EMD用阳极和阴极材料的最新研究进展,并对各类电极材料的特点做出简要的总结概括,同时对面向EMD生产用电极材料的研究与发展提出了设想与期望。

关键词：电解电解二氧化锰阳极材料阴极材料

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Nomogram predicting the prognosis of primary liver cancer after radiofrequency ablation combined with transcatheter arterial chemoembolization

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2630-2639页

作者： Hai-Hua Shen yu-Rong Hong Wen Xu Lei Chen Jun-Min Chen Zhi-Gen Yang Cai-Hong Chen Department of Ultrasound Hangzhou Linping Hospital of Traditional Chinese MedicineHangzhou 311106Zhejiang ProvinceChina Department of Ultrasound The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Nursing Hangzhou Linping Hospital of Traditional Chinese MedicineHangzhou 311106Zhejiang ProvinceChina

BACKGROUND The incidence and mortality rates of primary hepatocellular carcinoma(HCC)are high,and the conventional treatment is radiofrequency ablation(RFA)with transcatheter arterial chemoembolization(TACE);however,the 3-year survival rate is still ***,there are no visual methods to effectively predict their *** To explore the factors influencing the prognosis of HCC after RFA and TACE and develop a nomogram prediction *** Clinical and follow-up information of 150 patients with HCC treated using RFA and TACE in the Hangzhou linping Hospital of Traditional Chinese Medicine from May 2020 to December 2022 was retrospectively collected and *** examined their prognostic factors using multivariate logistic regression and created a nomogram prognosis prediction model using the R software(version 4.1.2).Internal verification was performed using the bootstrapping *** prognostic efficacy of the nomogram prediction model was evaluated using the concordance index(CI),calibration curve,and receiver operating characteristic RESULTS Of the 150 patients treated with RFA and TACE,92(61.33%)developed recurrence and *** regression analysis identified six variables,and a predictive model was *** internal validation results of the model showed a CI of *** correction curve trend of the prognosis prediction model was always near the diagonal,and the mean absolute error before and after internal validation was *** area under the curve of the prediction model after internal verification was 0.882[95%confidence interval(95%CI):0.820-0.945],with a specificity of 0.828 and sensitivity of *** to the Hosmer-Lemeshow test,χ2=3.552 and P=*** predictive model demonstrated a satisfactory calibration,and the decision curve analysis demonstrated its clinical *** The prognosis of patients with HCC after RFA and TACE is affected by several *** developed prediction model based

关键词： Nomogram Primary liver cancer Radiofrequency ablation Transcatheter arterial chemoembolization Prognosis Influencing factors Decision curve analysis

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Nutrient composition and distributions in coastal waters impacted by the Changjiang plume

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Acta Oceanologica Sinica 2008年第5期27卷 111-125页

作者： WANG Xiulin WANG Baodong ZHANG Chuansong SHI Xiaoyong ZHU Chenjian XIE linping HAN Xiurong XIN yu WANG Jiangtao College of Chemistry and Chemical Engineering Ocean University of China Qingdao 266100 China First Institute of Oceanography State Oceanic Administration Qingdao 266061 China

Four cruises were conducted during 2002--2003 in the Changjiang Estuary and adjacent coastal areas. The data presented show a clear coast to open sea gradient in nutrients related to the river inputs. Maximum values of chlorophyll a were typically observed at intermediate salinities at surface water and coincided with non-conservative decreases in nutrients along the salinity gradient, indicating that removal of nutrients was related to phytoplankton uptake. The seasonal variations of nutrient concentrations were just opposite to those of chlorophyll a, indicating that the seasonal variations of nutrients were mainly controlled by phytoplankton uptake, whereas riverine inputs merely weakened or balanced its extent. During the estuarine mixing, phosphate demonstrated some remobilization during all the four cruises; whereas both conservative and non-conservative behaviors for dissolved inorganic nitrogen and silicate were observed in the study area, indicating that both biotic and abiotic events may affect their behaviors during the estuarine mixing. Under the influence of freshwater inputs with high value of ratio of nitrogen to phosphorus, the estuarine and coastal waters impacted by the Changjiang plume were high （〉 30） in ratio of nitrogen to phosphorus, but rates of primary production were apparently not constrained by any kind of nutrient elements. However, the low （〈 1 ） ratio of silicate to nitrogen in most of the study area might be linked with the rapidly increasing frequency of harmful algal bloom （HAB） incidents in recent years in the coastal waters impacted by the Changjiang plume.

关键词： nutrients chlorophyll Changjiang River (Yangtze River) eutrophication mixing nutrient limitation

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单进水管结构对单通道矩形圆弧角养殖池水动力特性的影响研究

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大连海洋大学学报 2020年第1期35卷 134-140页

作者：于林平薛博茹任效忠刘鹰许条建史宪莹胡艺萱张倩大连海洋大学海洋与土木工程学院辽宁大连116023 设施渔业教育部重点实验室辽宁大连116023 大连海洋大学海洋科技与环境学院辽宁大连116023 大连理工大学海岸和近海工程国家重点实验室辽宁大连116024

为研究进水结构及其设计参数对循环水养殖池水动力特性的影响,采用流体动力学仿真技术,基于有限体积法和有限差分法建立三维数值计算模型,对矩形圆弧角养殖池在单进水管结构水力驱动模式下,不同射流孔数和进水管布设位置对养殖池内(尤... 详细信息

为研究进水结构及其设计参数对循环水养殖池水动力特性的影响,采用流体动力学仿真技术,基于有限体积法和有限差分法建立三维数值计算模型,对矩形圆弧角养殖池在单进水管结构水力驱动模式下,不同射流孔数和进水管布设位置对养殖池内(尤其是池底)流场的影响进行三维数值计算,并对排污口附近的复杂流场特征进行了重点分析。结果表明:提高日循环次数(本研究增加射流孔数)有利于增加养殖池内平均流速与速度分布均匀性;进水管布设于圆弧角位置是优选布设,有利于改善养殖池底部水动力特性。研究表明,进水管采用圆弧角位置布设,日循环次数为100~120次/d(本研究对应射流孔数为18~21个)时,养殖池内尤其是底部能达到较优流场状态,该结果可为工厂化循环水矩形圆弧角养殖池进水结构的参数设计和布设位置选择提供参考依据。

关键词：矩形圆弧角养殖池单进水管水动力特性数值模拟

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Spatiotemporal variations of ambient air pollutants and meteorological influences over typical urban agglomerations in China during the COVID-19 lockdown

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Journal of Environmental Sciences 2021年第8期33卷 26-38页

作者： linping Fan Shuang Fu Xin Wang Qingyan Fu Haohao Jia Hao Xu Guimei Qin Xue Hu Jinping Cheng School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China China National Environmental Monitoring Center Beijing 100012China Shanghai Environmental Monitor Center Shanghai 200235China

To investigate the air quality change during the COVID-19 pandemic,we analyzed spatiotemporal variations of six criteria pollutants in nine typical urban agglomerations in China using ground-based data and examined meteorological influences through correlation analysis and backward trajectory analysis under different *** of PM2.5,PM10,NO2,SO2 and CO in urban agglomerations respectively decreased by 18%–45%(30%–62%),17%–53%(22%–39%),47%-64%(14%–41%),9%–34%(0%–53%)and 16%-52%(23%–56%)during Lockdown(Post-lockdown)period relative to Pre-lockdown ***2.5 pollution events occurred during Lockdown in Beijing-Tianjin-Hebe(BTH)and Middle and South Liaoning(MSL),and daily O3 concentration rose to gradeⅡstandard in Post-lockdown *** from the nationwide slump of NO2 during Lockdown period,a rebound(~40%)in Post-lockdown period was observed in Cheng-yu(CY),Yangtze River Middle-Reach(YRMR),Yangtze River Delta(YRD)and Pearl River Delta(PRD).With slightly higher wind speed compared with 2019,the reduction of PM2.5(51%–62%)in Post-lockdown period is more than2019(15%–46%)in HC(Harbin-Changchun),MSL,BTH,CP(Central Plain)and SP(ShandongPeninsula),suggesting lockdown measures are effective to PM2.5 *** O3 concentrations generally increased during the lockdown,its increment rate declined compared with 2019 under similar sunlight duration and ***,unlike HC,MSL and BTH,which suffered from additional(>30%)air masses from surrounding areas after the lockdown,the polluted air masses reaching YRD and PRD mostly originated from the long-distance transport,highlighting the importance of joint regional governance.

关键词： COVID-19 Air pollutants Spatial and temporal variations Urban agglomeration Meteorological condition China

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