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基于胜任力的小儿麻醉专业可验证自学继续教育模式的探索与思考

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中国继续医学教育 2024年第7期16卷 156-160页

作者：唐林林刘立飞熊玲唐文罗庆徐颖重庆医科大学附属儿童医院/国家儿童健康与疾病临床医学研究中心/儿童发育疾病研究教育部重点实验室/儿童发育重大疾病国家国际科技合作基地/儿科学重庆市重点实验室/国家级继续医学教育基地/国家住院医师规范化培训示范基地麻醉科重庆401122

继续医学教育是保持、拓展和提高医学专业技术人员的知识、技能和专业能力的活动,是提高医务人员自身知识与技能的重要途径,可验证自学模式以个人发展需要为核心、自学为导向、提高岗位胜任力为目标的一种终身学习方式,是推进我国继续... 详细信息

继续医学教育是保持、拓展和提高医学专业技术人员的知识、技能和专业能力的活动,是提高医务人员自身知识与技能的重要途径,可验证自学模式以个人发展需要为核心、自学为导向、提高岗位胜任力为目标的一种终身学习方式,是推进我国继续教育改革的有力举措,文章针对重庆医科大学附属儿童医院2022—2023年关于可验证自学继续教育模式在麻醉科继续教育中的实施开展情况,制定了麻醉科关于可验证自学继续教育模式的教育形式和内容,运用现代化教育手段优化了学分管理,并对2022年及2023年继续教育学分行横向对比分析,总结了该继续教育模式在实施开展中的相关经验并提出优化措施,对进一步推广可验证自学模式在医学继续教育中的开展应用提供依据。

关键词：胜任力可验证自学继续教育小儿麻醉

Targeting calcium signaling in Alzheimer’s disease: challenges and promising therapeutic avenues

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Neural Regeneration Research 2024年第3期19卷 501-502页

作者： linlin Song YongPei tang Betty Yuen Kwan Law Neher’s Biophysics Laboratory for Innovative Drug Discovery State Key Laboratory of Quality Research in Chinese MedicineMacao University of Science and TechnologyMacao Special Administration RegionChina

The critical role of calcium dyshomeostasis in the pathogenesis of Alzheimer’s disease(AD):AD is a progressive neurodegenerative disease characterized by cognitive decline,memory impairment,and behavioral *** an estimated 50 million people being affected worldwide,the incidence of AD is constantly increasing *** hallmark of AD is the accumulation of amyloid-beta protein(Aβ)in the form of amyloid plaques and hyperphosphorylated tau protein in the form of neurofibrillary ***,increasing evidence suggests that calcium ion(Ca2+)dysregulation also plays a crucial role in the pathogenesis of AD(Calvo-Rodriguez and Bacskai,2021).As a key second messenger,Ca2+regulates a wide range of cellular processes,including the release of neurotransmitters,gene expression,and cell ***^(2+)also regulates the activity of Calcium/calmodulin-dependent protein kinase II,which is critical for synaptic plasticity,learning,and memory(Kaushik et al.,2022).Alternation in the Ca^(2+)signal is an early event in the pathogenesis of AD,which can lead to synaptic dysfunction,neuronal loss,and cognitive impairment.

关键词： Alzheimer homeostasis globally

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案例教学法在临床药物治疗学中的应用研究

国际医药卫生导报 2024年第9期30卷 1535-1538页

作者：唐琳琳武海艳丁传华段小菊潍坊医学院附属医院药学部潍坊261031 山东第一医科大学附属中心医院药学部济南250013 中国人民武装警察部队山东省总队医院药剂科济南250014

临床药物治疗学是药理学和临床医学之间的桥梁学科,本文探究了案例教学法应用于《临床药物治疗学》课程的教学效果。教师在临床实践中积累经典案例,通过经典案例的演示,提出问题,带动学生进行资料查询,将指南与案例相融合。通过案例教... 详细信息

临床药物治疗学是药理学和临床医学之间的桥梁学科,本文探究了案例教学法应用于《临床药物治疗学》课程的教学效果。教师在临床实践中积累经典案例,通过经典案例的演示,提出问题,带动学生进行资料查询,将指南与案例相融合。通过案例教学法的实施,调动学生自查自学临床指南、解决真实案例中存在问题的能力,激发学生学习热情,提高了我校临床药物治疗学教学水平,同时为培养具备合格药学服务能力的临床药师打下了基础。

关键词：临床药学案例教学法应用

Fast acquisition of L2C CL codes based on combination of hyper codes and averaging correlation

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Journal of Systems Engineering and Electronics 2016年第2期27卷 308-318页

作者： Qingxi Zeng linlin tang Pengna Zhang Ling Pei Vehicle Electronic Laboratory Nanjing University of Aeronautics and Astronautics Shanghai Key Laboratory of Navigation and Location Based Service Shanghai Jiao Tong University

This paper provides a direct and fast acquisition algorithm of civilian long length（CL） codes in the L2 civil（L2C） signal. The proposed algorithm simultaneously reduces the number of fast Fourier transformation（FFT） correlation through hyper code technique and the amount of points in every FFT correlation by using an averaging correlation method. To validate the proposed acquisition performance, the paper applies this algorithm to the real L2C signal collected by the global positioning system（GPS） L2C intermediate frequency（IF） signal sampler—SIS100L2C. The acquisition results show that the proposed modified algorithm can acquire the code phase accurately with less calculation and its acquisition performance is better than the single hyper code method.

关键词： L2C civilian long length(CL) code fast acquisition hyper code averaging correlation

Multifunctional mussel-inspired copolymerized epigallocatechin gallate(EGCG)/arginine coating:the potential as an ad-layer for vascular materials

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Regenerative Biomaterials 2016年第4期3卷 247-255页

作者： Rifang Luo linlin tang Lingxia Xie Jin Wang Nan Huang Yunbing Wang National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064China Key Lab of Advanced Technology of Materials of Education Ministry Southwest Jiaotong UniversityChengdu 610031China

Surface properties are considered to be important factors in addressing proper *** this paper,a multifunctional mussel-inspired coating was prepared via the direct copolymerization of epigallocatechin gallate(EGCG)and *** coating formation was confirmed by X-ray photoelectron spectroscopy and Fourier transform infrared *** EGCG/arginine coating contained diverse functional groups like amines,phenols and carboxyls,whose densities were also *** mussel-inspired coating could also be applied as an ad-layer for its secondary reactivity,demonstrated by quartz crystal microbalance ***,the tunable surface density of phenols showed potential ability in modulating endothelial cell and smooth muscle cell *** coatings rich in phenols presented excellent free radical scavenging *** results strongly indicated the potential of EGCG/arginine coatings to be applied as an ad-layer for vascular materials.

关键词： Mussel chemistry epigallocatechin gallate(EGCG) vascular devices surface modification multifunction

An active vibration control method based on energy-fuzzy for cantilever structures excited by aerodynamic loads

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Chinese Journal of Aeronautics 2021年第9期34卷 224-235页

作者： Wei LIU Weixiao LIU Mengde ZHOU linlin tang Qinqin WANG Zhengquan WEN Zhuang YAO Xiaojing YUAN Key Laboratory for Precision and Non-traditional Machining Technology of the Ministry of Education Dalian University of TechnologyDalian 116024China AVIC Aerodynamics Research Institute Shenyang 110034China

In wind tunnel tests for the full-model fixed with sting,the low structural damping of the long cantilever sting results in destructive low-frequency and large-amplitude *** order to obtain high-quality wind tunnel test data and ensure the safety of wind tunnel tests,an energy-fuzzy adaptive PD(Proportion Differentiation)control method is *** method is used for active vibration control of a cantilever structure under variable aerodynamic load excitation,and real-time adjustment of parameters is achieved according to the system characteristics of vibration ***,a real-time method is proposed to estimate the real-time vibration energy through the vibration acceleration signal,and the average exciting power of aerodynamic load is obtained by deducting the part of the power contributed by the vibration suppressor from the total ***,an energy-fuzzy adaptive PD controller is proposed to achieve adaptive control to the changes of the aerodynamic ***,the subsonic and transonic experiments were carried out in wind tunnel,the results revealed that comparing to fixed gain PD controllers,the energy-fuzzy adaptive PD controller maintains higher performance.

关键词： Active vibration control Cantilever structure Fuzzy logic PD controller Vibration energy analysis

A Triode-like Enzyme-free Catalytic Circuit with Junction Fuel

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Chemical Research in Chinese Universities 2020年第2期36卷 261-267页

作者： LUO Tao WANG Xiaojing FAN Sisi LIU Yan CHENG Jin tang linlin SONG Jie Institute of Nano Biomedicine and Engineering Department of Instrument Science and EngineeringSchool of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240P R.China

Target detection circuits have been previously designed,which are propelled by conventional PCR,isothermal amplification and strand-displacement *** detection circuits obtain the target signal via the replication of the target strand,the aggregation of the signal particles or the branch *** we constructed a tri-ode-like enzyme-free catalyst strand-displacement circuit for target DNA *** target strand triggered die reaction and released the fluorescence signal strand circularly through branch ***,the main challenge of strand-displacement reaction is the signal ***,we designed a double strand structure"junction fuel",which was used to increase the binding energy across the displacement ***,the leakage of the system obtained stable inhabitation due to the junction fuel *** limit of detection of the system was as low as 0.11 nmol/L and the gain of the system was as high as 28-fold(the concentration of target was 50 nmol/L).Furthermore,the process of the system was visualized vividly in the reaction curve through the kinetic simulation implemented,which suggests that the combination of the kinetic simulation and the experiment exhibits a promising prospect towards the use of strand-displacement circuit in analytical,diagnostic application and synthetic biology.

关键词： Catalysis Strand-displacement Junction fuel Triode-like Kinetic simulation

不同转速下基于深度注意力迁移学习的滚动轴承故障诊断方法

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振动与冲击 2022年第12期41卷 95-101,195页

作者：陈仁祥唐林林胡小林杨黎霞赵玲重庆交通大学交通工程应用机器人重庆市工程实验室重庆400074 重庆工业大数据创新中心有限公司重庆400056 重庆科技学院工商管理学院重庆401331

针对不同转速下滚动轴承故障诊断中特征提取困难、数据分布差异巨大影响诊断结果,提出一种不同转速下基于深度注意力迁移学习(deep attention transfer learning,DATL)的滚动轴承故障诊断方法。首先,利用小波变换获取振动信号的时频图... 详细信息

针对不同转速下滚动轴承故障诊断中特征提取困难、数据分布差异巨大影响诊断结果,提出一种不同转速下基于深度注意力迁移学习(deep attention transfer learning,DATL)的滚动轴承故障诊断方法。首先,利用小波变换获取振动信号的时频图以展现时频特征;其次,搭建融合空间和通道的注意力卷积神经网络(attention convolutional neural network,ACNN)提取滚动轴承的关键特征以防止特征丢失;然后,在ACNN中添加领域适配层,完成不同转速下滚动轴承深度特征的迁移适配;最后,通过Softmax分类层对目标数据进行故障状态识别。通过不同转速下不同故障程度的滚动轴承故障诊断试验证明了所提方法的可行性和有效性。

关键词：滚动轴承不同转速注意力机制迁移学习故障诊断

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全自动液体处理工作站设计

农业装备技术 2022年第2期48卷 30-32,36页

作者：姚阳汤淋淋南通理工学院江苏南通226000 硅湖职业技术学院江苏昆山215300

针对国内液体处理工作站自动化程度较低、模块化功能较少、可靠性不足、稳定性较差等缺点进行了全自动液体处理工作站的结构设计,主要包括底座及定位结构、机械臂的选型和移液模块设计,并对移液模块的关键结构进行了详细分析,为以后液... 详细信息

针对国内液体处理工作站自动化程度较低、模块化功能较少、可靠性不足、稳定性较差等缺点进行了全自动液体处理工作站的结构设计,主要包括底座及定位结构、机械臂的选型和移液模块设计,并对移液模块的关键结构进行了详细分析,为以后液体处理工作站的设计提供了有效参考。

关键词：液体机械臂移液