Multifunctional mussel-inspired copolymerized epigallocatechin gallate(EGCG)/arginine coating:the potential as an ad-layer for vascular materials

作     者：Rifang Luo Linlin Tang Lingxia Xie Jin Wang Nan Huang Yunbing Wang 

作者机构：National Engineering Research Center for BiomaterialsSichuan UniversityChengdu 610064China Key Lab of Advanced Technology of Materials of Education MinistrySouthwest Jiaotong UniversityChengdu 610031China 

出 版 物：《Regenerative Biomaterials》 (再生生物材料（英文版）)

年 卷 期：2016年第3卷第4期

页      面：247-255页

核心收录：

学科分类：08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：The author would like to thank Dr Manfred.F.Maitz for his selfless assistance of this job and appreciate Mr Chongxi Jiang and Mrs Ru Shen for their help and contributions on sample characterization and analysis.Specially thank Miss Si Zhong and Mr Xin Wang for their help of cell compatibility evaluation.This work was supported by Natural Science Foundation of China(Grant 51173149,81330031 and 31270020) Sichuan Province Science and Technology Support Program(No.2014SZ0128) the 111 Project.The Program of Introducing Talents of Discipline to Universities(B16033) 

主　　题：Mussel chemistry epigallocatechin gallate(EGCG) vascular devices surface modification multifunction 

摘      要：Surface properties are considered to be important factors in addressing proper *** this paper,a multifunctional mussel-inspired coating was prepared via the direct copolymerization of epigallocatechin gallate(EGCG)and *** coating formation was confirmed by X-ray photoelectron spectroscopy and Fourier transform infrared *** EGCG/arginine coating contained diverse functional groups like amines,phenols and carboxyls,whose densities were also *** mussel-inspired coating could also be applied as an ad-layer for its secondary reactivity,demonstrated by quartz crystal microbalance ***,the tunable surface density of phenols showed potential ability in modulating endothelial cell and smooth muscle cell *** coatings rich in phenols presented excellent free radical scavenging *** results strongly indicated the potential of EGCG/arginine coatings to be applied as an ad-layer for vascular materials.