检索结果-南通市图书馆

健康快讯：1999-2012年美国非吸烟者的二手烟暴露差异

在线全文

学校读者我要写书评

暂无评论

上海预防医学 2016年第9期28卷 666-670页

作者： David M.Homa linda j.neff Brian A.King Ralph S.Caraballo Rebecca E.Bunnell Stephen D.Babb Bridgette E.Garrett Connie S.Sosnoff Lanqing Wang 宋彦(翻译) 金克峙(审校) 蔡颖(审校) Office on Smoking and Health National Center for Chronic Disease Prevention and Health Promotion CDC Division of Laboratory Sciences National Center for Environmental Health CDC 不详

1介绍烟草燃烧产生的二手烟暴露会导致在婴儿和儿童中发生幼儿猝死综合征（sudden infant death syndrome,SIDS）、呼吸道感染、耳部炎症和哮喘发作等;在成人非吸烟者中会导致冠心病、中风和肺癌。不存在没有风险的二手烟暴露水平。每年... 详细信息

1介绍烟草燃烧产生的二手烟暴露会导致在婴儿和儿童中发生幼儿猝死综合征（sudden infant death syndrome,SIDS）、呼吸道感染、耳部炎症和哮喘发作等;在成人非吸烟者中会导致冠心病、中风和肺癌。不存在没有风险的二手烟暴露水平。每年,二手烟暴露导致超过4.1万例成人非吸烟者及400例婴儿死亡,并造成每年约56亿美元的生产力损失。

关键词：婴儿死亡 sudden 呼吸道感染人群暴露住房状况暴露率公共住房 infant 无应答偏倚自有住房

Extreme Antarctic Cold of Late Winter 2023

在线全文

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2024年第10期41卷 1873-1880页

作者： Anastasia j.TOMANEK David E.MIKOLAjCZYK Matthew A.LAZZARA Stefano DI BATTISTA Minghu DING Mariana FONTOLAN LITELL David H.BROMWICH Taylor P.NORTON linda M.KELLER Lee j.WELHOUSE Antarctic Meteorological Research and Data Center Space Science and Engineering CenterUniversity of Wisconsin-MadisonMadisonWisconsin 53706USA Department of Physical Sciences School of EngineeringScienceand MathematicsMadison Area Technical CollegeMadisonWisconsin 53704USA Meteogiornale via Paolo Diacono9Milano 20133Italy State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Byrd Polar and Climate Research Center The Ohio State UniversityColumbusOhio 43210USA Department of Geography The Ohio State UniversityColumbusOhio 43210USA

Extreme cold temperatures were observed in july and August 2023,coinciding with the WINFLY(winter fly-in)period of mid to late August into September 2023,meaning aircraft operations into McMurdo Station and Phoenix Airfield were adversely ***,with temperatures below−50℃,safe flight operation was not possible because of the risk of failing hydraulics and fuel turning to gel onboard the *** cold temperatures were measured across a broad area of the Antarctic,from East Antarctica toward the Ross Ice Shelf,and stretching across West Antarctica to the Antarctic Peninsula.A review of automatic weather station measurements and staffed station observations revealed a series of sites recording new record low *** separate cold phases were identified,each a few days in duration and occurring from mid-july to the end of August 2023.A brief analysis of 500-hPa geopotential height anomalies shows how the mid-tropospheric atmospheric environment evolves in relation to these extreme cold *** monthly 500-hPa geopotential height anomalies show strong negative anomalies in *** of composite geopotential height anomalies during each of the four cold phases suggests various factors leading to cold temperatures,including both southerly off-content flow and calm atmospheric *** the atmospheric environment that leads to such extreme cold temperatures can improve prediction of such events and benefit Antarctic operations and the study of Antarctic meteorology and climatology.

关键词： Antarctica extreme cold temperature automatic weather station networks

在线全文

学校读者我要写书评

暂无评论

被迫迁徙的企鹅

地球 2008年第5期 62-63页

作者： Kevin j.neff

南极冰川融化听起来可能不痛不痒，看见企鹅脚下尽是下一代的残骸。才是气候变化最震撼、最直接的证据。南极洲东部的冰原曾经是帝王企鹅的理想生存领地．但现在帝王企鹅的“乐土”已经消失了，放眼望去根本看不到小的帝王企鹅，只剩下... 详细信息

南极冰川融化听起来可能不痛不痒，看见企鹅脚下尽是下一代的残骸。才是气候变化最震撼、最直接的证据。南极洲东部的冰原曾经是帝王企鹅的理想生存领地．但现在帝王企鹅的“乐土”已经消失了，放眼望去根本看不到小的帝王企鹅，只剩下十来座冰山。企鹅对环境十分敏感，有什么变化它们能够先感受到。由它们的悲惨命运可以看出，地球的自然环境正在明显恶化。

关键词：企鹅迁徙自然环境冰川融化气候变化南极洲冰山地球

Integrated Risk Identification, Analysis, and Assessment:A Dynamic Household Economy Analysis Methodology and Example

在线全文

学校读者我要写书评

暂无评论

International journal of Disaster Risk Science 2013年第2期4卷 77-88页

作者： Bob Alexander linda j.Cox junko Mochizuki Rural Livelihood Risk Management Consulting P.O.Box 1251HonoluluHI 96807USA Department of Natural Resource and Environmental Management University of Hawai`i at ManoaHonoluluHI 96822USA

Many methodologies identify, analyze, and assess static risks to quantify potential disaster losses based on past and current events. Static methodologies will not, however, capture how climate change and adaptation are rapidly affecting the natural and social systems in many areas. Local and global changes such as those associated with development investments, livelihood pressures, political stability, and demographic trends are also affecting many areas, especially in emerging economies. Risk identification, analysis, and assessment methodologies must integrate all changes dynamically so that risk reduction and development decisions can be based on future needs. After a theoretical explanation of how to integrate dynamic changes, a static Household Economy Analysis(HEA) completed for a rapidly changing area of East Timor was altered using current trends to make the analysis more dynamic. Some inherent difficulties exist with a more dynamic approach and recommendations for overcoming them are presented. Research, government, and nongovernment personnel interested in integrated approaches to risk reduction and development decision-making in areas subject to rapid change will find the study useful.

关键词： integrate disaster interested

Closed 3-stop Center and Periphery in Graphs

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2012年第3期28卷 439-452页

作者： linda EROH Ralucca GERA Steven j. WINTERS Department of Mathematics University of Wisconsin Oshkosh Department of Applied Mathematics Naval Postgraduate School

A delivery person must leave the central location of the business, deliver packages at a number of addresses, and then return. Naturally, he/she wishes to reduce costs by finding the most efficient route. This motivates the following： Given a set of k distinct vertices S = {x1, x2,..., xk } in a simple graph G, the closed k-stop-distance of set S is defined to be

关键词： Central appendage number peripheral appendage number Steiner distance

Case-control study of factors that trigger inflammatory bowel disease flares

在线全文

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2014年第15期20卷 4329-4334页

作者： linda A Feagins Ramiz Iqbal Stuart j Spechler VA North Texas Healthcare System DallasTX 75216United States Division of Gastroenterology University of Texas Southwestern Medical CenterDallasTX 75216United States

AIM: To explore the association between inflammatory bowel diseases (IBD) flares and potential triggers.

关键词： Inflammatory bowel diseases, Flare, Non-adherence, Crohn’ s disease, Ulcerative colitis

Iodoacetic acid exposure alters the transcriptome in mouse ovarian antral follicles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

journal of Environmental Sciences 2022年第7期34卷 46-57页

作者： Andressa Gonsioroski Mary Laws Vasiliki E.Mourikes Alison neff jenny Drnevich Michael j.Plewa jodi A.Flaws Department of Comparative Biosciences University of Illinois Urbana-ChampaignUrbanaIllinois 61801USA Roy j.Carver Biotechnology Center University of Illinois Urbana-ChampaignUrbanaIllinois 61801USA Department of Crop Sciences and the Safe Global Water Institute University of Illinois Urbana-ChampaignUrbanaIllinois 61801USA

Iodoacetic acid(IAA) is an unregulated water disinfection byproduct that is an ovarian toxicant. However, the mechanisms of action underlying IAA toxicity in ovarian follicles remain unclear. Thus, we determined whether IAA alters gene expression in ovarian follicles in mice. Adult female mice were dosed with water or IAA(10 or 500 mg/L) in the water for 35-40 days. Antral follicles were collected for RNA-sequencing analysis and sera were collected to measure estradiol. RNA-sequencing analysis identified 1063 differentially expressed genes(DEGs) in the 10 and 500 mg/L IAA groups(false discovery rate FDR < 0.1), respectively, compared to controls. Gene Ontology Enrichment analysis showed that DEGs were involved with RNA processing and regulation of angiogenesis(10 mg/L) and the cell cycle and cell division(500 mg/L). Pathway Enrichment analysis showed that DEGs were involved in the phosphatidylinositol 3-kinase and protein kinase B(PI3K-Akt), gonadotropin-releasing hormone(Gn RH), estrogen, and insulin signaling pathways(10 mg/L). Pathway Enrichment analysis showed that DEGs were involved in the oocyte meiosis, Gn RH, and oxytocin signaling pathways(500 mg/L). RNA-sequencing analysis identified 809 DEGs when comparing the 500 and 10 mg/L IAA groups(FDR < 0.1). DEGs were related to ribosome, translation, m RNA processing, oxidative phosphorylation, chromosome, cell cycle, cell division, protein folding, and the oxytocin signaling pathway. Moreover, IAA exposure significantly decreased estradiol levels(500 mg/L) compared to control. This study identified key candidate genes and pathways involved in IAA toxicity and can help to further understand the molecular mechanisms of IAA toxicity in ovarian follicles.

关键词： Disinfection byproducts Iodoacetic acid Ovary Ovarian follicles Steroidogenesis Endocrine disruptors

A primer on stochastic epidemic models:Formulation,numerical simulation,and analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Disease Modelling 2017年第2期2卷 128-142页

作者： linda j.S.Allen Department of Mathematics and Statistics Texas Tech UniversityLubbockTX 79409-1042USA

Some mathematical methods for formulation and numerical simulation of stochastic epidemic models are ***,models are formulated for continuous-time Markov chains and stochastic differential *** well-known examples are used for illustration such as an SIR epidemic model and a host-vector malaria *** methods for approximating the probability of a disease outbreak are also discussed.

关键词： Branching process Continuous-time Markov chain Minor outbreak Stochastic differential equation

Harnessing memory adaptive regulatory T cells to control autoimmunity in type 1 diabetes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

分子细胞生物学报:英文版 2012年第1期4卷 38-47页

作者： Cheng-Rui Li Bas j.G.Baaten linda M.Bradley Infectious and Inflammatory Disease Center Sanford-Burnham Medical Research Institute10901 North Torrey Pines RoadLa JollaCA 92037USA

Type 1 diabetes(T1D)results from autoimmune destruction of insulin-producing b-cells in the pancreatic *** is an immediate need to restore both b-cell function and immune tolerance to control disease progression and ultimately cure ***,there is no effective treatment strategy to restore glucose regulation in patients with ***3-expressing CD4^(+) regulatory T cells(Tregs)are potential candidates to control autoimmunity because they play a central role in maintaining ***,deficiencies in either naturally occurring Tregs(nTregs)themselves and/or their ability to control pathogenic effector T cells have been associated with ***,we hypothesize that nTregs can be replaced by FoxP3^(+) adaptive Tregs(aTregs),which are uniquely equipped to combat autoreactivity in *** nTregs,aTregs are stable and provide long-lived *** this review,we summarize the current understanding of aTregs and their potential for use as an immunological intervention to treat T1D.

关键词： type 1 diabetes adaptive regulatory T cells autoimmunity immunotherapy