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journal of Environmental Sciences 2024年第1期135卷 669-680页

作者： Meichen Wang Kelly j Rivenbark Timothy D phillips Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and aminomethylphosphonic acid(AMPA)in contaminated water,soil,sediment and plants is a cause for concern due to potential threats to the ecosystem and human health.A major route of exposure is through contact with contaminated soil and consumption of crops containing GLP and AMPA ***,clay-based sorption strategies for mixtures of GLP and AMPA in soil,plants and garden produce have been very *** this study,in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP and AMPA in soils and their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil and 0.5%-1%in plants)and duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium montmorillonite(CM)and acid processed montmorillonite(APM)clays at all doses significantly and consistently reduced the bioavailability of both chemicals from soils to plant roots and leaves in a dose-and time-dependent manner without detectable *** treated with 0.5%and 1%APM inclusion showed the highest growth rate(p≤0.05)and lowest chemical bioavailability with up to 76%reduction in roots and57%reduction in *** indicated that montmorillonite clays could be added as soil supplements to reduce hazardous mixtures of GLP and AMPA in soils and plants.

关键词： Glyphosate AMPA Adsorption Soil remediation Plant Hydroponic system

评估多氯联苯吸入所导致的健康风险:解决不确定性的研究需求

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环境与职业医学 2015年第6期32卷 534-534页

作者： Geniece M.Lehmann Krista Christensen Mark Maddaloni linda j.phillips

[背景]在一些建筑物内,多氯联苯(PCBs)的室内空气浓度要比背景值高出一个甚至更多的数量级。为此,人们试图评估吸入PCBs所造成的潜在健康风险。但是由于来源、暴露和暴露-反应的特征描述以及评估中存在着不确定性,这些尝试受到了阻碍。... 详细信息

[背景]在一些建筑物内,多氯联苯(PCBs)的室内空气浓度要比背景值高出一个甚至更多的数量级。为此,人们试图评估吸入PCBs所造成的潜在健康风险。但是由于来源、暴露和暴露-反应的特征描述以及评估中存在着不确定性,这些尝试受到了阻碍。[目的]简要介绍室内空气中PCBs的一些常见来源,并估计特定年龄组的吸入暴露对总PCBs暴露的贡献量。随后,确定需要进行重点研究的领域,以提高对PCBs吸入暴露和暴露反应的评估水平。[讨论]虽然美国在1979年就开始禁止生产PCBs,但在此之前建造的许多建筑中仍含有潜在的污染来源,造成室内空气PCBs污染。在一些室内条件下和一些年龄组中,吸入暴露对PCBs总暴露的贡献可能大于其他任何暴露途径。PCBs暴露与人体健康效应相关,但针对吸入途径的数据仍然很少。为了进行暴露-反应评估,在今后研究PCBs吸入的健康效应时要仔细考虑研究设计的一些方面,包括描述PCBs混合暴露的特征,这一点十分重要。[结论]在某些情况下,PCBs的吸入暴露对PCBs总暴露的贡献量可能比以前认为的更多。新的流行病学和毒理学研究致力于解决PCBs吸入对健康的潜在影响,可能有助于确定暴露-反应关系和进行风险评估。

关键词： PCBs 氯联苯背景值贡献量毒理学研究室内条件人体健康风险评估污染来源暴露途径

Extreme Antarctic Cold of Late Winter 2023

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Advances in Atmospheric Sciences 2024年第10期41卷 1873-1880页

作者： Anastasia j.TOMANEK David E.MIKOLAjCZYK Matthew A.LAZZARA Stefano DI BATTISTA Minghu DING Mariana FONTOLAN LITELL David H.BROMWICH Taylor P.NORTON linda M.KELLER Lee j.WELHOUSE Antarctic Meteorological Research and Data Center Space Science and Engineering CenterUniversity of Wisconsin-Madison Department of Physical Sciences School of Engineering Science and MathematicsMadison Area Technical College Meteogiornale State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences Byrd Polar and Climate Research Center The Ohio State University Department of Geography The Ohio State University

Extreme cold temperatures were observed in july and August 2023, coinciding with the WINFLY(winter fly-in)period of mid to late August into September 2023, meaning aircraft operations into Mc Murdo Station and Phoenix Airfield were adversely impacted. Specifically, with temperatures below-50℃, safe flight operation was not possible because of the risk of failing hydraulics and fuel turning to gel onboard the aircraft. The cold temperatures were measured across a broad area of the Antarctic, from East Antarctica toward the Ross Ice Shelf, and stretching across West Antarctica to the Antarctic Peninsula. A review of automatic weather station measurements and staffed station observations revealed a series of sites recording new record low temperatures. Four separate cold phases were identified, each a few days in duration and occurring from mid-july to the end of August 2023. A brief analysis of 500-hPa geopotential height anomalies shows how the mid-tropospheric atmospheric environment evolves in relation to these extreme cold temperatures. The monthly 500-hPa geopotential height anomalies show strong negative anomalies in August. Examination of composite geopotential height anomalies during each of the four cold phases suggests various factors leading to cold temperatures, including both southerly off-content flow and calm atmospheric conditions. Understanding the atmospheric environment that leads to such extreme cold temperatures can improve prediction of such events and benefit Antarctic operations and the study of Antarctic meteorology and climatology.

关键词： Antarctica extreme cold temperature automatic weather station networks

磷酸钙涂覆炭织物体外细胞毒性的评价(英文)

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新型炭材料 2008年第2期23卷 139-143页

作者：韩红梅 Gary j.phillips Sergey V．Mikhalovsky Andrew W．Lloyd 仲恺农业技术学院化工系广东广州510225 布来顿大学生物分子科学与药学院英国布来顿BN2 4GJ

医用植入体的成功与否常常取决于器件植入后细胞与材料表面间的相互作用。采用生物体外测试法考察了声电化学法制备的磷酸钙涂层对炭织物的骨细胞附着、增殖能力的影响。借助MTS检测技术、扫描电子显微镜,选择人类成骨细胞(MG63)作为细... 详细信息

医用植入体的成功与否常常取决于器件植入后细胞与材料表面间的相互作用。采用生物体外测试法考察了声电化学法制备的磷酸钙涂层对炭织物的骨细胞附着、增殖能力的影响。借助MTS检测技术、扫描电子显微镜,选择人类成骨细胞(MG63)作为细胞模型,通过测定细胞与炭织物、磷酸钙涂覆炭织物、以及其各自的提取液作用后的存活能力,研究了细胞/材料的相互作用,并对基底材料的细胞毒性进行了评价。结果表明,炭织物、磷酸钙涂覆炭织物均不具有细胞毒性,且磷酸钙涂层可提高成骨细胞的附着和增殖。SEM图像显示,细胞形貌正常,与对照组相比较生长增殖情况相似。

关键词：炭纤维磷酸钙细胞毒性生物体外测试

声电化学法在炭织物表面制备的磷酸钙涂层及其对成骨细胞活性的影响(英文)

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新型炭材料 2007年第2期22卷 121-125页

作者：韩红梅 Sergey V.Mikhalovsky Gary j.phillips Andrew W.Lloyd 布赖顿大学生物分子科学与药学院

为了研究炭纤维增强羟基磷灰石(HA)复合材料对骨修复的影响,采用声电化学沉积法在炭纤维织物表面直接制备磷酸钙涂层。电解液为含钙、磷离子的溶液,初始pH值4.7,沉积温度50℃。借助红外光谱、扫描电子显微镜及能谱分析对涂层的结构、形... 详细信息

为了研究炭纤维增强羟基磷灰石(HA)复合材料对骨修复的影响,采用声电化学沉积法在炭纤维织物表面直接制备磷酸钙涂层。电解液为含钙、磷离子的溶液,初始pH值4.7,沉积温度50℃。借助红外光谱、扫描电子显微镜及能谱分析对涂层的结构、形貌、组分就行了研究,并选择人类成骨细胞(MG63)检测了材料的体外细胞相容性。结果表明,超声波的迭加使用改变了磷酸钙沉积层的组分和形貌,与传统的电化学工艺相比更具优势。MTS检测证明,用声电法沉积的磷酸盐涂层更大幅度地提高了成骨细胞的附着和增殖。

关键词：炭纤维磷酸钙生物体外测试细胞活性扫描电镜

Storylines of family medicine Ⅴ:ways of thinking—honing the therapeutic self

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Family Medicine and Community Health 2024年第S3期12卷 43-51页

作者： William B Ventres Leslie A Stone johanna F Shapiro Cynthia Haq jéssica R B Leao Donald E Nease jr Liz Grant Stewart W Mercer john C M Gillies Pablo González Blasco Maria Auxiliadora C De Benedetto Graziela Moreto Marcelo R Levites jennifer E DeVoe William R phillips jane M Uygur Thomas R Egnew Colette S Stanley Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine University of California Irvine School of MedicineIrvineCaliforniaUSA Faculty of Medicine University of Sao PauloSao PauloBrazil Family Medicine University of Colorado Anschutz Medical Campus School of MedicineAuroraColoradoUSA Usher Institute Edinburgh Medical SchoolUniversity of EdinburghEdinburghUK SOBRAMFA-Medical Education and Humanism Sao PauloBrazil Family Medicine Oregon Health&Science University School of MedicinePortlandOregonUSA Family Medicine University of Washington School of MedicineSeattleWashingtonUSA General Practice Royal College of Surgeons in IrelandDublinIreland General Internal Medicine Geriatrics&Palliative MedicineTulane University School of MedicineNew OrleansLouisianaUSA

Storylines of Family Medicine is a 12-part series of thematically linked essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅴ:ways of thinking—honing the therapeutic self’,authors present the following sections:‘Reflective practice in action’,‘The doctor as drug—Balint groups’,‘Cultivating compassion’,‘Towards a humanistic approach to doctoring’,‘Intimacy in family medicine’,‘The many faces of suffering’,‘Transcending suffering’and‘The power of listening to stories.’May readers feel a deeper sense of their own therapeutic agency by reflecting on these essays.

关键词： illustration dimensions suffering

Time dependent integration of matrix metalloproteinases and their targeted substrates directs axonal sprouting and synaptogenesis following central nervous system injury

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Neural Regeneration Research 2014年第4期9卷 362-376页

作者： linda L.phillips julie L.Chan Adele E.Doperalski Thomas M.Reeves Department of Anatomy and Neurobiology Virginia Commonwealth UniversityRichmondVAUSA

Over the past two decades, many investigators have reported how extracellular matrix molecules act to regulate neuroplasticity. The majority of these studies involve proteins which are targets of matrix metalloproteinases. Importantly, these enzyme/substrate interactions can regulate degenerative and regenerative phases of synaptic plasticity, directing axonal and dendritic reorganization after brain insult. The present review first summarizes literature support for the prominent role of matrix metalloproteinases during neuroregeneration, followed by a discussion of data contrasting adaptive and maladaptive neuroplasticity that reveals time-dependent metalloproteinase/substrate regulation of postinjury synaptic recovery. The potential for these enzymes to serve as therapeutic targets for enhanced neuroplasticity after brain injury is illustrated with experiments demonstrating that metalloproteinase inhibitors can alter adaptive and maladaptive outcome. Finally, the complexity of metalloproteinase role in reactive synaptogenesis is revealed in new studies showing how these enzymes interact with immune molecules to mediate cellular response in the local regenerative environment, and are regulated by novel binding partners in the brain extracellular matrix. Together, these different examples show the complexity with which metalloproteinases are integrated into the process of neuroregeneration, and point to a promising new angle for future studies exploring how to facilitate brain plasticity.

关键词： neuroregeneration reactive synaptogenesis matrix metalloproteinases brain injury adaptive and maladaptive neuroplasticity metalloproteinase inhibition osteopontin lipocalin 2

The Potential for Homestead Pond Polyculture of Tilapia and Carps in Coastal Bangladesh

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journal of Fisheries Science 2019年第1期1卷 15-25页

作者： Md.Abdul Wahab Md.jimi Reza Mir Mohammad Ali Md.Nahiduzzaman Michael j.phillips WorldFish Bangladesh and South Asia OfficeBananiDhaka-1213Bangladesh Department of Aquaculture Sher-e-Bangla Agricultural UniversityDhaka-120Bangladesh WorldFish Head Quarter PenangMalaysia

A fishers’women-led Participatory Action Research(PAR)was conducted in 30 homestead ponds to assess the potential for polyculture of Tilapia(Oreochromis niloticus)and major carps Rohu(Labeo rohita)and Catla(Catla catla)in two coastal fishing villages of *** treatments,namely T1(Tilapia 200 fish per decimal;1 decimal=40 m^2),T2(Tilapia 200+Rohu 32+Catla 8 fish per decimal)and T3(Tilapia 200+Rohu 8+Catla 32 fish per decimal),each with 5 replicates,were tried in Hossainpur and Anipara *** commercial Mega-feed was applied to the ponds twice daily at an initial rate of 10%body weight(bw)/day of Tilapia down to 4%bw/day throughout the culture *** water quality parameters of ponds including transparency,salinity and dissolved oxygen significantly varied among treatments except temperature and pH and remained within optimum range for carp polyculture except *** survival rate,harvesting weight and yield of Tilapia were significantly highest in T1(85.63±05%,258.59±18.76 g&11073±805 kg/ha,respectively)in Anipara and lowest in T3(75.63±0.37%,136.97±10.63 g&5180±406 kg/ha,respectively)in *** gross fish production was the significantly highest in T1(11354±806 kg/ha)of Anipara and lowest in T1(6325±227 kg/ha)of ***,the highest net return(866,627±84874 BDT/ha)was found in T1 of Anipara and lowest in T3(279,389±46104 BDT/ha)of Hossainpur with a significantly higher benefit-cost ratio(BCR)obtained in T1(3.26±0.20)for Tilapia and lower in T3(1.58±0.10)for polyculture Tilapia and carp of ***,it may be concluded that Tilapia production in small homestead coastal ponds has a higher potential than its mix with carps in polyculture for generating food and supplemental income opportunity for coastal fishers’women in Bangladesh.

关键词： PAR Tilapia Carps Polyculture Bangladesh

Integrated Risk Identification, Analysis, and Assessment:A Dynamic Household Economy Analysis Methodology and Example

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International journal of Disaster Risk Science 2013年第2期4卷 77-88页

作者： Bob Alexander linda j.Cox junko Mochizuki Rural Livelihood Risk Management Consulting P.O.Box 1251HonoluluHI 96807USA Department of Natural Resource and Environmental Management University of Hawai`i at ManoaHonoluluHI 96822USA

Many methodologies identify, analyze, and assess static risks to quantify potential disaster losses based on past and current events. Static methodologies will not, however, capture how climate change and adaptation are rapidly affecting the natural and social systems in many areas. Local and global changes such as those associated with development investments, livelihood pressures, political stability, and demographic trends are also affecting many areas, especially in emerging economies. Risk identification, analysis, and assessment methodologies must integrate all changes dynamically so that risk reduction and development decisions can be based on future needs. After a theoretical explanation of how to integrate dynamic changes, a static Household Economy Analysis(HEA) completed for a rapidly changing area of East Timor was altered using current trends to make the analysis more dynamic. Some inherent difficulties exist with a more dynamic approach and recommendations for overcoming them are presented. Research, government, and nongovernment personnel interested in integrated approaches to risk reduction and development decision-making in areas subject to rapid change will find the study useful.

关键词： integrate disaster interested

Closed 3-stop Center and Periphery in Graphs

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Acta Mathematica Sinica,English Series 2012年第3期28卷 439-452页

作者： linda EROH Ralucca GERA Steven j. WINTERS Department of Mathematics University of Wisconsin Oshkosh Department of Applied Mathematics Naval Postgraduate School

A delivery person must leave the central location of the business, deliver packages at a number of addresses, and then return. Naturally, he/she wishes to reduce costs by finding the most efficient route. This motivates the following： Given a set of k distinct vertices S = {x1, x2,..., xk } in a simple graph G, the closed k-stop-distance of set S is defined to be

关键词： Central appendage number peripheral appendage number Steiner distance