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International journal of Disaster Risk Science 2013年第2期4卷 77-88页

作者： Bob Alexander linda j.cox junko Mochizuki Rural Livelihood Risk Management Consulting P.O.Box 1251HonoluluHI 96807USA Department of Natural Resource and Environmental Management University of Hawai`i at ManoaHonoluluHI 96822USA

Many methodologies identify, analyze, and assess static risks to quantify potential disaster losses based on past and current events. Static methodologies will not, however, capture how climate change and adaptation are rapidly affecting the natural and social systems in many areas. Local and global changes such as those associated with development investments, livelihood pressures, political stability, and demographic trends are also affecting many areas, especially in emerging economies. Risk identification, analysis, and assessment methodologies must integrate all changes dynamically so that risk reduction and development decisions can be based on future needs. After a theoretical explanation of how to integrate dynamic changes, a static Household Economy Analysis(HEA) completed for a rapidly changing area of East Timor was altered using current trends to make the analysis more dynamic. Some inherent difficulties exist with a more dynamic approach and recommendations for overcoming them are presented. Research, government, and nongovernment personnel interested in integrated approaches to risk reduction and development decision-making in areas subject to rapid change will find the study useful.

关键词： integrate disaster interested

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William j.Flerlage Mark L.Dell’Acqua Brian M.cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

Burnout in the emergency department: Randomized controlled trial of an attention-based training program

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journal of Integrative Medicine 2019年第3期17卷 173-180页

作者： Pádraic j.Dunne julie Lynch Lucia Prihodova Caoimhe O'Leary Atiyeh Ghoreyshi Sharee A.Basdeo Donal j.cox Rachel Breen Ali Sheikhi áine Carroll Cathal Walsh Geraldine McMahon Barry White Trinity Translational Medicine Institute Trinity College Research Department Royal College of Physicians of Ireland Department of Innovation Fitbit Inc. Health Research Institute Main BuildingUniversity of Limerick Health Service Executive Dr Steevens' Hospital Department of Emergency Medicine St.James' s Hospital National Centre for Hereditary Coagulation Disorders St.James' s Hospital

Background: Burnout(encompassing emotional exhaustion, depersonalization and personal accomplishment) in healthcare professionals is a major issue worldwide. Emergency medicine physicians are particularly affected, potentially impacting on quality of care and attrition from the ***: The aim of this study was to apply an attention-based training(ABT) program to reduce burnout among emergency multidisciplinary team(MDT) members from a large urban ***, setting, participants and interventions: Emergency MDT members were randomized to either a notreatment control or an intervention group. Intervention group participants engaged in a four session(4 h/session) ABT program over 7 weeks with a practice target of 20 min twice-daily. Practice adherence was measured using a smart phone application together with a wearable Charge 2 *** outcome measures: The primary outcome was a change in burnout, comprising emotional exhaustion, depersonalization and personal achievement. The secondary outcomes were changes in other psychological and biometric ***: The ABT program resulted in a significant reduction(P < 0.05; T1 [one week before intervention]vs T3 [follow-up at two months after intervention]) in burnout, specifically, emotional exhaustion, with an effect size(probability of superiority) of 59%. Similar reductions were observed for stress(P < 0.05) and anxiety(P < 0.05). Furthermore, ABT group participants demonstrated significant improvements in heart rate variability, resting heart rate, sleep as well as an increase in pro-inflammatory cytokine ***: This study describes a positive impact of ABT on emergency department staff burnout compared to a no-treatment control group.

关键词： Burnout Emotional exhaustion Meditation Healthcare professional Sleep Stress Cytokines Cortisol Randomized controlled trial

Mapping of a dominantly inherited spinocerebellar ataxia with azoospermia to chromosome 7q32.3

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Mapping of a dominantly inherited spinocerebellar ataxia wit...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Nancy j.cox Christopher M.Gomez Section of Genetic Medicine Department of MedicineUniversity of ChicagoChicago60637USA Department of Neurology University of Chicago Medical CenterChicagoIllinois 60637USA

＜正＞The dominantly inherited spinocerebellar ataxias（SCA） are a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by progressive imbalance,dysarthria and motor *** distinct SCA subtypes can only be distinguished consistently by genetic *** identified a five-generation kindred of french ancestry inherited as an autosomal dominant trait that is associated with a novel form of progressive ataxia and cognitive impairment,in which all affected males are *** disorder is inherited only from affected or presymptomatic *** affected individuals including 9 females and 11 males,particularly females,have a broad range of age of onset, which is significantly much later than male *** neuropsychological evaluations demonstrated cognitive impairment with borderline IQ scores for those with onset of ataxia before 40 years *** magnetic resonance imaging demonstrates cerebellar *** males had testicular atrophy and *** biopsy from one sterile male demonstrated complete absence of germ cells and *** exclusion of mutations in or linkage to known SCA loci and genes,fragile X,X-linkage,Y-chromosome microdeletion,we carried out a genome-wide genetic linkage scan and located the disease locus to chromosome 7q32.3 by two-point analysis（a maximal two-point LOD score of 3.59,9=0） and haplotype-based *** of one candidate disease-causing gene（transiently secret） within the region using a recombinant DNA sequencing approach including TA clone method,which carried（ATTCT）n pentanucleotide repeat units in intron 31,revealed an interesting small difference in the size of repeat between affected and normal individuals in the pedigree,for which more normal controls should be detected and confirmed for co-segregation in the *** of the gene responsible for this complex phenotype may shed additional light into the pa

关键词： dominantly inherited spinocerebellar ataxia kindred clinical characteristics mapping

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江苏化工 1984年第S1期 6-7页

作者： j.cox 法国罗素—优克福公司市场部部长

溴氰菊酯,作为新一代的拟除虫菊醣农药在农业上的开发应用,十年前始于法国并很快地推广到全世界。1979年在中华人民共和国也开始了大规模的田间试验,就世界范围而言,溴氰菊酯已经在一百多个国家的40多种作物上进行了卓有成效的试验。法... 详细信息

溴氰菊酯,作为新一代的拟除虫菊醣农药在农业上的开发应用,十年前始于法国并很快地推广到全世界。1979年在中华人民共和国也开始了大规模的田间试验,就世界范围而言,溴氰菊酯已经在一百多个国家的40多种作物上进行了卓有成效的试验。法国罗素—优克福公司生产的2.5％溴氰菊酯乳油,商品名称为敌杀死(Decis~),其突出的特点是对害虫具有极高的生物活性以及极低的使用剂量,每亩只用有效成份0.2—1.0

关键词：福公司优克敌杀死克福罗素除虫菊宿根花卉

Heat Transfer to Foods: Modelling and Validation

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journal of Thermal Science 2002年第4期11卷 320-330页

作者： P.W.cox P.j.Fryer Centre for Formulation Engineering Chemical Engineering University of BirminghamCentre for Formulation Engineering Chemical Engineering University of Birmingham Edgbaston Birmingham UK Edgbaston Birmingham UK

The food industry uses a wide variety of processes which are not well understood. Current modelling and measurement approaches are reviewed, with specific reference to work at Birmingham on Particle tracking (PEPT) an... 详细信息

关键词： heat transfer food processing.

Molecular advances in pancreatic cancer:A genomic,proteomic and metabolomic approach

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World journal of Gastroenterology 2021年第31期27卷 5171-5180页

作者： Srujan Rajesh Michael j.cox Franscois Runau Department of General Surgery Leicester General HospitalLeicester LE54PWUnited Kingdom

Pancreatic ductal adenocarcinoma(PDAC)represents a challenging pathology with very poor outcomes and is increasing in incidence within the general *** majority of patients are diagnosed incidentally with insidious symptoms and hence present late in the disease *** significantly affects patient outcomes:the only cure is surgical resection but only up to 20%of patients present with resectable disease at the time of clinical *** use of“omic”technology is expanding rapidly in the field of personalised medicine-using genomic,proteomic and metabolomic approaches allows researchers and clinicians to delve deep into the core molecular processes of this difficult *** review gives an overview of the current findings in PDAC using these“omic”approaches and summarises useful markers in aiding clinicians treating *** strategies incorporating these findings and potential application of these methods are presented in this review article.

关键词： Pancreatic ductal adenocarcinoma,Pancreatic adenocarcinoma Genomic Proteomic Metabolomic

采用薄膜过滤系统回收制浆造纸厂的副产品及有机化学药品

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Paper And Biomaterials 1983年第5期 44-45页

作者： j.cox 刘贤增

在制浆生产过程中,不少木材固体物最终溶于制浆废液之中。此种废液主要通过蒸发、燃烧来回收热能和无机化学药品,其结果导致有价值的有机化学品及其他有用的物质损失。为过滤溶解的固体物而设计的薄膜系统,证明是一种通过从废液中回收... 详细信息

在制浆生产过程中,不少木材固体物最终溶于制浆废液之中。此种废液主要通过蒸发、燃烧来回收热能和无机化学药品,其结果导致有价值的有机化学品及其他有用的物质损失。为过滤溶解的固体物而设计的薄膜系统,证明是一种通过从废液中回收木素或其他有机物来处理废液行之有效的方法。

关键词：反渗透法预浓缩固体物废液无机物废物反渗透设备多效蒸发器薄膜过滤副产品药品

Closed 3-stop Center and Periphery in Graphs

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Acta Mathematica Sinica,English Series 2012年第3期28卷 439-452页

作者： linda EROH Ralucca GERA Steven j. WINTERS Department of Mathematics University of Wisconsin Oshkosh Department of Applied Mathematics Naval Postgraduate School

A delivery person must leave the central location of the business, deliver packages at a number of addresses, and then return. Naturally, he/she wishes to reduce costs by finding the most efficient route. This motivates the following： Given a set of k distinct vertices S = {x1, x2,..., xk } in a simple graph G, the closed k-stop-distance of set S is defined to be

关键词： Central appendage number peripheral appendage number Steiner distance

Case-control study of factors that trigger inflammatory bowel disease flares

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World journal of Gastroenterology 2014年第15期20卷 4329-4334页

作者： linda A Feagins Ramiz Iqbal Stuart j Spechler VA North Texas Healthcare System DallasTX 75216United States Division of Gastroenterology University of Texas Southwestern Medical CenterDallasTX 75216United States

AIM: To explore the association between inflammatory bowel diseases (IBD) flares and potential triggers.

关键词： Inflammatory bowel diseases, Flare, Non-adherence, Crohn’ s disease, Ulcerative colitis