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Restimate:Recovery Estimation Tool for Resilience Planning

Journal of Safety Science and Resilience 2024年第1期5卷 47-63页

作者： Scott Miles Megan ly Nick Terry Youngjun Choe Department of Human Centered Design&Engineering Campus Box 352315University of WashingtonSeattleWA 98195United States of America Department of Industrial&Systems Engineering Box 352650University of WashingtonSeattleWA 98195United States of America

The *** Institute of Standards and Technology(NIST)published the Community Resilience Planning Guide in *** NIST Guide advocates for a participatory process for developing a performance measurement framework for the jurisdiction’s resilience against a scenario *** framework centers around tables of expected and desired recovery times for selected community assets,such as electricity,water,and natural gas *** NIST Guide does not provide a method for estimating the expected recovery ***,building high-fidelity computer models for such estimations requires substantial resources that even larger ju-risdictions cannot *** most promising approach to recovery time estimation is to systematically use data elicited from people to tap into the wisdom of the(knowledgeable)*** paper describes a novel research-through-design project to enable the computer-supported elicitation of recovery time series *** work is the first in the literature to examine people’s ability to estimate recovery curves and how design in-fluences such *** main contribution to resilience planning is three-fold:development of a new elicitation tool called Restimate,understanding its potential user base,and providing insights into how it can facilitate resilience *** is the first tool to enable evidence-based expert elicitation in any community with limited resources for resilience *** resilience planning,those who facilitate high-stakes planning activities under large uncertainties(e.g.,mission-critical system design and planning)will benefit from a similar research-through-design process.

关键词： expert elicitation disaster natural hazard infrastructure community resilience restoration user-centered design computer-supported cooperative work

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Projective Hilbert modules and sequential approximations

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Science China Mathematics 2025年第01期 137-168页

作者： Lawrence G.Brown Huaxin lin Department of Mathematics Purdue University Department of Mathematics East China Normal University Department of Mathematics University of Oregon Shanghai Institute for Mathematics and Interdisciplinary Sciences

We show that when A is a separable C*-algebra,every countably generated Hilbert A-module is projective（with bounded module maps as morphisms）.We also study the approximate extensions of bounded module *** the case where A is a σ-unital simple C*-algebra with strict comparison,and every strictly positive lower semicontinuous affine function on quasitraces can be realized as the rank of an element in the Cuntz semigroup,we show that the Cuntz semigroup is equivalent to unitarily equivalent classes of countably generated Hilbert A-modules if and only if A has stable rank one.

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Stochastic ordering by g-expectations

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Probability, Uncertainty and Quantitative Risk 2021年第1期6卷 61-98页

作者： Sel ly Nicolas Privault School of Physical and Mathematical Sciences Division of Mathematical SciencesNanyang Technological UniversitySingapore 637371

We derive sufficient conditions for the convex and monotonic g-stochastic ordering of diffusion processes under nonlinear g-expectations and *** approach relies on comparison results for forward-backward stochastic differential equations and on several extensions of convexity,monotonicity,and continuous dependence properties for the solutions of associated semilinear parabolic partial differential *** to contingent claim price comparison under different hedging portfolio constraints are provided.

关键词： Stochastic ordering g-expectation g-evaluation g-risk measures Forward-backward stochastic differential equations Parabolic PDEs Propagation of convexity

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Integrating immunoinformatics and computational epitope prediction for a vaccine candidate against respiratory syncytial virus

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Infectious Disease Modelling 2024年第3期9卷 763-774页

作者： Truc ly Nguyen Heebal Kim Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences Seoul National UniversitySeoul08826Republic of Korea Interdisciplinary Program in Bioinformatics Seoul National UniversitySeoul08826Republic of Korea eGnome Inc.Seoul05836Republic of Korea

Respiratory syncytial virus(RSV)poses a significant global health threat,especially affecting infants and the *** this,the present study proposes an innovative approach to vaccine design,utilizing immunoinformatics and computational *** analyzed RSV's structural proteins across both subtypes A and B,identifying potential helper T lymphocyte,cytotoxic T lymphocyte,and linear B lymphocyte *** such as antigenicity,allergenicity,toxicity,and cytokine-inducing potential were rigorously ***,we evaluated the conservancy of these epitopes and their population coverage across various RSV *** comprehensive analysis identified six major histocompatibility complex class I(MHC-I)binding,five MHC-II binding,and three B-cell *** were integrated with suitable linkers and adjuvants to form the ***,molecular docking and molecular dynamics simulations demonstrated stable interactions between the vaccine candidate and human Toll-like receptors(TLR4 and TLR5),with a notable preference for *** simulation analysis underscored the vaccine's potential to elicit a strong immune *** study presents a promising RSV vaccine candidate and offers theoretical support,marking a significant advancement in vaccine development ***,the promising in silico findings need to be further validated through additional in vivo studies.

关键词： Respiratory syncytial virus Multiepitope vaccine Immunoinformatics Docking molecular Molecular dynamics simulation Immune simulation

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Experimental investigation on phase transformation type micropump

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Chinese Science Bulletin 2002年第6期47卷 518-522页

作者： Li, ZX Wang, MR Tan, ly Tsing Hua Univ Dept Engn Mech Beijing 100084 Peoples R China

The phase transformation type micropump without moving parts was experimentally studied in this note. To analyze the pumping mechanism of the micropump, a simplified physical model was presented. The experimental results indicate that the pump characteristic is mainly dependent on the heating and cooling conditions. For a given system, there exist an optimal combination of heating current and switch time with which the flow rate reaches maximum. Comparing with the natural cooling, the forced con-vective cooling needs larger heating current to obtain the same flow rate. In our experiments, the maximum flow rate is 33μL/min when the inner diameter of the micropump is 200μm, and the maximum pumping pressure reaches over 20 kPa. The theoretical analysis shows that the pumping mechanism of the micropump mainly lies in the large density difference between liquid and gas phases and the effect of gas chocking.

关键词： micropump phase transformation pumping character-istic.

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Enzymohistochemical study on burn effect on rat intestinal NOS

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World Journal of Gastroenterology 2000年第3期6卷 421-423页

作者： Wang QG He ly Chen YW Hu SL Xianning Med Coll Dept Neurobiol Xianning 437100 Hubei Province Peoples R China

INTRODUCTION The blood irrigate flow obstruction,especially thegastrointestinal(GI)ischemia,is the main factorof the damage to the digestive tract caused byserious *** effect of GI ischemia on thewhole body is extensive and profound,which notonly causes the increase of intestinal permeabilityand the movement of bacteria and toxin in theintestinal cavity,but releases a large quantity ofinflammatory *** element

关键词： nitric oxide burn intestines superoxide dismutase MDA GSH-PX

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Do aeolian deposits and sand encroachment intensity shape patterns of vegetation diversity and plant functional traits in desert pavements?

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Journal of Arid Land 2023年第6期15卷 667-694页

作者： M'hammed BOUALLALA Souad NEFFAR lyès BRADAI Haroun CHENCHOUNI Laboratory of Saharan Natural Resources Faculty of Sciences and TechnologyUniversity of Ahmed DraiaAdrar 01000Algeria Department of Nature and Life Sciences Faculty of Exact Sciences and Nature and Life SciencesUniversity of TebessaTebessa 12002Algeria Laboratory Water and Environment University of TebessaTebessa 12002Algeria Laboratory of Saharan Bioresources Preservation and Valorization Faculty of Nature and Life SciencesUniversity of Kasdi MerbahOuargla 30000Algeria Department of Forest Management Higher National School of ForestsKhenchela 40000Algeria Laboratory of Natural Resources and Management of Sensitive Environments University of Oum-El-BouaghiOum-El-Bouaghi 04000Algeria

The effects of sand encroachment on composition,diversity,and functional patterns of vegetation in drylands are rarely studied,and yet addressing these aspects is important to deepen our understanding of the biodiversity *** study aimed to investigate the effect of sand encroachment on plant functional biodiversity of desert pavements(gravel deserts)in the Sahara Desert of *** were sampled and analyzed in three desert pavements with different levels of sand encroachment(LSE)and quantity of aeolian deposits(low,LLSE;medium,MLSE;and high,HLSE).Within the sample-plot area(100 m^(2)),density of every plant species was identified and total vegetation cover was *** taxonomic and functional diversity were analyzed and compared between *** showed that 19 plant species in desert pavements were classified into 18 genera and 13 *** and Poaceae were the most important *** species Anabasis articulata(Forssk)*** LLSE desert pavements with 11 species,whereas Thymelaea microphylla Coss.&Durieu ex *** Calobota saharae(C&D)Boatwr.&van Wyk were dominant species of desert pavements with MLSE(14 species)and HLSE(10 species),*** highest values of species richness and biodiversity were recorded in desert pavements with MLSE,while low values of these ecological parameters were obtained in desert pavements with *** pavements with LLSE were characterized with the highest values of species *** communities were dominated by chamaephytes,anemochorous,arido-active,and competitive stress-tolerant *** increase in LSE along the gradient from LLSE to HLSE induced significant changes in plant community variables including decreases in plant density,plant rarity,lifeform composition,morphological type,and aridity *** pavements with HLSE favor the degradation of vegetation and trigger biodiversity erosion.

关键词： desert pavements hot and arid rangeland plant diversity land degradation sand encroachment plant functional trait Sahara Desert

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Interface effect on the giant magnetoresistance for different magnetic multilayers systems

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Chinese Science Bulletin 1997年第9期42卷 729-733页

作者： Zhang, ly Sun, H Li, BZ Pu, FK Institute of Physics Chinese Academy of Sciences Beijing China State Key Laboratory of Molecular Reaction Dynamics Institute of Chemistry Chinese Academy of Sciences Beijing China

THE giant magnetoresistance(GMR)effect in magnetic multilayer has been the subject of in-tense investigation since its *** theories,including semiclassical theoryand quantum theory,have been developed to deal with the... 详细信息

关键词： magnetic multilayer interface effect giant magnetoresistance Anderson model.

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Trend and Characteristics of Variation on the Runoff of the …

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中国沙漠 2000年第3期20卷 273-277页

作者： Chao,ly jun,JH

根据唐乃亥等有关台站的水文气象观测资料，对黄河上唐乃亥以上流域的径注琢演变规律进行了分析探讨，并在此基础上用灰色拓扑、混合门限自回归及周期外延－逐步回归等数学模型对其未来的变化趋势进行了预测。结果表明，黄河上游唐乃... 详细信息

根据唐乃亥等有关台站的水文气象观测资料，对黄河上唐乃亥以上流域的径注琢演变规律进行了分析探讨，并在此基础上用灰色拓扑、混合门限自回归及周期外延－逐步回归等数学模型对其未来的变化趋势进行了预测。结果表明，黄河上游唐乃亥以上流域径流目前正处于一个枯水段的底部，并且从现在超的今后若干年里将呈现一个波动状上升的变化趋势。

关键词：径流特性演变规律变化规律趋势预测周期分析

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磁性纳米材料与磁场效应加速骨损伤修复

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中国组织工程研究 2025年第4期29卷 827-838页

作者：肖放黄雷王琳华中科技大学同济医学院附属协和医院组织工程与再生医学研究中心湖北省武汉市430022 华中科技大学同济医学院附属协和医院检验科湖北省武汉市430022

背景:磁性纳米材料具有促进干细胞成骨分化和抑制破骨细胞形成等生物活性,并在磁场协同下有效促进损伤骨组织愈合,在骨损伤修复中具有广阔的应用前景。目的:综述磁性纳米材料与磁场促进骨修复的作用机制,及其在骨损伤修复领域的研究进... 详细信息

背景:磁性纳米材料具有促进干细胞成骨分化和抑制破骨细胞形成等生物活性,并在磁场协同下有效促进损伤骨组织愈合,在骨损伤修复中具有广阔的应用前景。目的:综述磁性纳米材料与磁场促进骨修复的作用机制,及其在骨损伤修复领域的研究进展。方法:在PubMed和Web of Science数据库中进行相关文献检索,检索词为“magnetic nanomaterials,magnetic field,bone repair,bone tissue engineering,stem cell,osteoblast,osteoclast”。检索文献时限为2003-2023年,将其进行筛选和分析,最终纳入98篇文献进行分析。结果与结论:①磁性纳米材料具有促成骨细胞分化、抑制破骨细胞形成和调节免疫微环境等生物效应;此外,磁性纳米材料可调节组织工程支架的机械性能和表面形貌等理化性质,并赋予其磁性,有利于调控干细胞的黏附、增殖与成骨分化。②磁场具有调控细胞内多条信号通路发挥促成骨细胞分化、抑制破骨细胞形成和刺激血管生成等生物学效应,从而加速损伤的骨组织愈合。③磁性纳米材料与磁场的联合应用,通过激活机械转导、增加细胞内磁性纳米粒子含量、增强微磁场效应等加速骨损伤修复,为骨组织工程的研究提供了新的思路。④磁场在临床骨折、骨质疏松症和骨关节炎疾病的治疗中展现出确切疗效,促进骨组织生长、减轻骨质流失和缓解疼痛,改善患者的生活质量。⑤磁性纳米材料与磁场在骨损伤修复与再生中应用潜力大,但磁性纳米材料、磁场和细胞之间的相互作用机制尚未完全阐明,而且磁场调控细胞内分子事件的关键参数,包括磁场类型、强度、频率、作用时间和作用方式等,以及特定磁场对骨细胞的精确生物效应和潜在机制仍有待明确。⑥未来需要进一步关注其对损伤组织微环境中的破骨细胞、神经、血管和免疫细胞的影响,而关于磁性材料用于人体安全性问题,有待系统性研究其分布、代谢以及急性和慢性毒性等。

关键词：磁性纳米材料磁场骨修复骨组织工程干细胞成骨细胞破骨细胞

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