检索结果-南通市图书馆

Research progress of microwave plasma ignition and assisted combustion

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2023年第12期36卷 53-76页

作者： liming he Yunwei ZHANG Hao ZENG Bingbing ZHAO Aviation Engineering School Air Force Engineering UniversityXi’an 710038China

As the low temperature non-equilibrium plasma,microwave plasma has the same effects with the plasma produced by the traditional high voltage electrode,which has the function of widening ignition boundary and improving combustion.Microwave has the advantages of uniformity,particle selectivity and no electrode.It can generate a large range of non-equilibrium plasma with relatively low power without electrode ablation.Therefore,how to maximize its effectiveness has become the research hotspot of ignition and combustion in engines.At present,the related research mainly focuses on microwave plasma discharge and microwave assisted spark ignition.The results show that it can broaden lean and rich burn flammability limits,improve combustion efficiency,accelerate flame propagation speed,and reduce pollutant emissions.This paper summarizes the related research at home and abroad in recent years,the main conclusion is that how the microwave plasma affects the turbulence intensity of flow field will be the promising research,and the research trend of microwave plasma ignition and assisted combustion in future will be the research of microwave assisted plasma igniter.

关键词： Combustion Engines Ignition Microwave technology Plasma

Targeting the resolution pathway of inflammation using Ac2–26 peptide-loaded PEGylated lipid nanoparticles for the remission of rheumatoid arthritis

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2021年第4期16卷 483-493页

作者： Xianyan Qin liming he Donghao Fan Wenlang Liang Qin Wang Jiyu Fang Key Laboratory of Advanced Technologies of Materials Ministry of Education and School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China Advanced Materials Processing and Analysis Center and Department of Materials Science and Engineering University of Central FloridaFlorida 32816United State

Rheumatoid arthritis(RA)is a common autoimmune disease characterized by joint inflammation and immune dysfunction.Although various therapeutic approaches have been utilized for the treatment of RA in clinical applications,the low responsiveness of RA patients and undesired systemic toxicity are still unresolved problems.Targeting the resolution pathway of inflammation with pro-resolving mediators would evoke the protective actions of patient for combating the inflammation.Ac2–26,a 25-amino acid peptide derived from Annexin A(a pro-resolving mediator),has shown good efficacy in the treatment of inflammatory disorders.However,the low bioavailability of Ac2–26 peptides hinders their efficacy in vivo.In this paper,we formed PEGylated lipid nanoparticles(LDNPs)by the co-assembly of l-ascorbyl palmitate(L-AP)and N-(carbonyl methoxypolyethylene glycol-2000)-1,2-distearoyl-sn–glycero-3-phosphoethanolamine(DSPE-PEG 2 k)to encapsulate and deliver Ac2–26 peptides to the arthritic rats.They showed good stability and biocompatibility.After being intravenously administrated,Ac2–26 peptide-loaded PEGylated lipid nanoparticles(ADNPs)showed the prolonged in vivo circulation time and enhanced accumulation in inflamed sites.In vivo therapeutic evaluations revealed that ADNPs could attenuate synovial inflammation and improve joint pathology.Therefore,the pro-resolving therapeutic strategy using ADNPs is effective in RA treatment.

关键词： Pegylated lipid nanoparticles Drug delivery Pro-resolving therapy Ac2–26 peptide Rheumatoid arthritis

Biomechanical evaluation of two fusion techniques based on finite element analysis:Percutaneous endoscopic and minimally invasive transforaminal lumbar interbody fusion

在线全文

学校读者我要写书评

暂无评论

Medicine in Novel Technology and Devices 2022年第4期16卷 17-25页

作者： Yang Yan Jiarui Li Jianhao Yu Yan Wang Hao Dong Yuqin Sun Xiaogang Wu liming he Weiyi Chen Haoyu Feng College of Biomedical Engineering Taiyuan University of TechnologyTaiyuan030024China Shanxi Bethune Hospital Shanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuan030032China

As a novel minimally invasive technique,percutaneous endoscopic transforaminal lumbar interbody fusion(PETLIF)has been widely used in the treatment of lumbar degenerative diseases.The purpose of this study was to analyze these two operation types’biomechanical performances of PE-TLIF and traditional minimally invasive transforaminal lumbar interbody fusion(MIS-TLIF)using the finite element(FE)method.The intact FE models of L4-L5 were established and validated based on the CT images.On this basis,the FE models of MIS-TLIF and PETLIF were established and analyzed.It is demonstrated that for lumbar interbody fusion with the oblique asymmetrically implanted cage under bilateral pedicle screws and rods fixation,such as MIS-TLIF and PE-TLIF,different degrees of articular process resection have no significant effect on the cage subsidence,and the surgical segment can achieve similar stability.In addition,the maximum stress of the L4 inferior endplate of MIS-TLIF and PE-TLIF is greater than that of the L5 superior endplate,which indicates that MIS-TLIF and PE-TLIF can cause cage subsidence in the L4 inferior endplate.

关键词： Percutaneous endoscopic transforaminal lumbar interbody fusion Minimally invasive surgery Degenerative lumbar diseases Finite element analysis Biomechanics

The influence of radial entrance width of the circular cavity on incident shock wave focusing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Propulsion and Power Research 2018年第2期7卷 120-128页

作者： Xin Chen Chuan Wang Sheng Tan liming he Qiang Zhang Aeronautics and Astronautics Engineering College Air Force Engineering UniversityXi’an 710038China Aerospace Science and Engineering College National University of Defense TechnologyChangsha 410071China

Despite the achievement of shock wave focusing with certain reflectors,the influence of the radial entrance width of a circular cavity on the flow field has yet to be addressed.In this study,we systematically investigated the effects of the shock wave focusing process in a cavity based on the radial entrance widths.An experimental system was installed to research the evolution of the flow field under conditions with different radial entrance widths of 3.0,11.1,19.5,and 33.0 mm.A schlieren system was used to photograph the structures of the flow field in the cavity,and a data acquisition system was used to record the dynamic pressure histories of different points.A numerical simulation was carried out to investigate greater details of the shock wave focusing process.A third-order strong stability-preserving Runge-Kutta method,third-order weighed essential non-oscillation scheme,and an adaptive mesh refinement algorithm were adopted to simulate the shock wave reflection,diffraction,and focus process.Good agreement between the experimental and numerical results was observed.By comparing the evolution process of the flow field under the conditions of four different entrance cavity widths,we found that when the entrance width was 19.5 mm,there was the stronger intensity of the shock wave focusing in the focal region,and the larger pressure value at the apex of the cavity than the other three entrance widths,occur.This study improves our understanding of shock wave focusing.

关键词： Shock wave focusing Radial entrance widths Cavity Schlieren system Weighed essential nonoscillation

Experimental study of rotating gliding arc discharge plasma-assisted combustion in an aero-engine combustion chamber

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2019年第2期32卷 337-346页

作者： liming he Yi CheN Jun DENG Jianping LEI Li FEI Pengfei LIU Science and Technology on Plasma Dynamics Laboratory Aeronautics and Astronautics Engineering CollegeAir Force Engineering University

The combustion chamber is the core component of an aero-engine, and affects its reliability and security operation, even the performance of the aircraft. In this work, a Plasma-Assisted Combustion(PAC) test platform was developed to validate the feasibility of using PAC actuators to enhance annular combustor performance. Two plans of PAC(rotating gliding arc discharge plasma) were designed, Assisted Combustion from Primary Holes(ACPH) and Assisted Combustion from Dilution Holes(ACDH). Comparative experiments and analysis between conventional combustion and PAC were conducted to study the effects of ACPH and ACDH on the performances including average outlet temperature, combustion efficiency, pattern factor under four different excessive air coefficients(0.8, 1, 2, and 4), and lean blowout performance at different inlet airflow velocities. Experimental results show that the combustion efficiency is improved after PAC compared with that in normal conditions, and the combustion efficiency of ACPH increases2.45%, 1.49%, 1.04%, and 0.47%, while it increases 2.75%, 1.67%, 1.36%, and 0.36% under ACDH conditions. The uniformity of the outlet temperature field and the lean blowout performance are improved after PAC. Especially for ACPH, the widening of the lean blowout limit is8.3%, 12.4%, 12.8%, and 25% respectively when the inlet velocity ranges from 60 m/s to120 m/s. These results offer new perspectives for using PAC devices to enhance aero-engine combustors' performances.

关键词： Aero-engine Assisted combustion actuator Combustion chambers Plasma-Assisted Combustion Rotating gliding arc discharge

在线全文

学校读者我要写书评

暂无评论

一种灵芝菌种液氮保藏方法的研究

北方园艺 2024年第10期 92-98页

作者：蔡凌贺黎铭谢欣刘林秋罗霞四川省中医药科学院菌类药材研究所菌类药材系统研究与开发实验室四川成都610041 中药材品质及创新中药研究四川省重点实验室四川成都610041

以“药灵芝1号”为试材,采用三因素三水平的液氮保藏正交实验,对萌发率、恢复时间、菌丝生长速率、菌丝体干质量4个指标进行保藏效果综合评价,以期建立一种灵芝菌种液氮保藏方法,再以10个不同灵芝菌种使用该保藏方法进行保藏效果的验证... 详细信息

以“药灵芝1号”为试材,采用三因素三水平的液氮保藏正交实验,对萌发率、恢复时间、菌丝生长速率、菌丝体干质量4个指标进行保藏效果综合评价,以期建立一种灵芝菌种液氮保藏方法,再以10个不同灵芝菌种使用该保藏方法进行保藏效果的验证。结果表明:最优保藏方案为采用-80℃液氮的降温方式,10%甘油作为保护剂,常温解冻复苏。10个不同灵芝菌种应用该保藏方法后均可萌发,恢复时间范围在1~7 d,80%菌种菌丝生长速率保藏前后无显著变化、100%菌种菌丝体干质量保藏前后无显著变化,ISSR共扩增出611条片段,大小范围在300~3000 bp,保藏前菌种和保藏后菌种在相同引物下的扩增条带一致,未发现变异现象。因此,该研究的液氮保藏方法可保障保藏菌种的萌发率、恢复时间、菌丝生长速率、菌丝体干质量等指标,适用于多种灵芝菌种的保藏,普适性强,应用范围广,且操作简便,具有良好的应用前景。

关键词：灵芝液氮保藏 ISSR

内镜下单侧椎板切开双侧减压技术治疗脊柱退行性疾病的研究进展

在线全文

学校读者我要写书评

暂无评论

河北医药 2024年第9期46卷 1403-1406,1411页

作者：李亚坤何李明冯皓宇山西医科大学第三医院(山西白求恩医院山西医学科学院同济山西医院) 太原市030032

近年来,单侧椎板切开双侧减压(unilateral laminotomy for bilateral decompression,ULBD)技术在脊柱外科领域已经成为一种新兴的手术技术,得到越来越多研究者的认可。内镜辅助下行ULBD技术,术中可以获得更加清晰的视野而避免损伤硬膜... 详细信息

近年来,单侧椎板切开双侧减压(unilateral laminotomy for bilateral decompression,ULBD)技术在脊柱外科领域已经成为一种新兴的手术技术,得到越来越多研究者的认可。内镜辅助下行ULBD技术,术中可以获得更加清晰的视野而避免损伤硬膜囊及神经根,在保留脊柱的生理解剖结构的同时增大了术后脊柱稳定性,提高患者满意度及生活质量。该技术要求术者对解剖结构、手术步骤及器械有足够的认知,所以陡峭的学习曲线已然是该技术的一个难点。本文针对内镜下ULBD技术的发展历史、临床应用、应用前景,以及适应证、禁忌证和并发症等多个方面进行综述。

关键词：单侧椎板切开双侧减压内镜腰椎管狭窄症腰椎滑脱症融合微创

不同补播模式对荒漠草原植物群落特征及土壤养分的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中国草地学报 2024年第5期46卷 14-22页

作者：姚敏赵佳乐王忠武韩国栋赫黎明侯东杰王海明内蒙古农业大学草原与资源环境学院/草地资源教育部重点实验室内蒙古呼和浩特010011 内蒙古自治区农牧业科学院内蒙古呼和浩特010031

为了解补播对荒漠草原草地植被恢复的影响及作用,在短花针茅(Stipa breviflora)荒漠草原开展了围封补播试验,设置5个处理,分别为对照(补播机械不加种子作业一次,CK)、单播新麦草(Psathyrostachys juncea,XX)、单播冰草(Agropyron crista... 详细信息

为了解补播对荒漠草原草地植被恢复的影响及作用,在短花针茅(Stipa breviflora)荒漠草原开展了围封补播试验,设置5个处理,分别为对照(补播机械不加种子作业一次,CK)、单播新麦草(Psathyrostachys juncea,XX)、单播冰草(Agropyron cristatum,BB)、单播黄花苜蓿(Medicago falcata,HH)以及混播新麦草、冰草、黄花苜蓿(BXH),于植物生长季(8月)进行植物群落调查,并对土壤以及植物进行取样分析。结果表明,补播能够显著提高植物地上生物量,且单播新麦草处理有显著影响(P<0.05)。补播对多年生杂类草高度、密度有抑制作用,使Margalef丰富度指数有所升高,而使Shannon-Wiener多样性指数和Pielou均匀度指数下降,但均无显著影响,并且补播处理下土壤养分无显著变化。在植物群落特征指标与土壤养分指标相关性分析中发现,植物平均高度和盖度是影响植物地上生物量的显著因子,土壤全磷含量对植物高度影响显著,且土壤全氮含量与土壤全磷含量显著正相关(P<0.05)。结果初步表明补播措施对于荒漠草原草地植被以及土壤的改善具有积极意义,可为后续补播对荒漠草原草地的影响研究提供参考。

关键词：荒漠草原补播群落特征土壤养分植物功能群

万古霉素治疗儿童革兰阳性球菌感染的疗效及安全性分析

在线全文

学校读者我要写书评

暂无评论

中国感染与化疗杂志 2024年第3期24卷 257-264页

作者：何丽明范亚新闫钢风王一雪张菁陆国平陶金好复旦大学附属儿科医院重症医学科上海201102 复旦大学附属华山医院抗生素研究所

目的分析革兰阳性球菌感染患儿应用万古霉素治疗后的药物浓度和暴露量,以及临床疗效和安全性,为临床提供合理应用参考。方法前瞻性收集2012年1月至2021年3月复旦大学附属儿科医院87例革兰阳性球菌感染患儿的临床和实验室资料,进行万古... 详细信息

目的分析革兰阳性球菌感染患儿应用万古霉素治疗后的药物浓度和暴露量,以及临床疗效和安全性,为临床提供合理应用参考。方法前瞻性收集2012年1月至2021年3月复旦大学附属儿科医院87例革兰阳性球菌感染患儿的临床和实验室资料,进行万古霉素治疗药物监测(TDM),并计算24 h药时曲线下面积(AUC_(0-24h))和AUC_(0-24h)/最低抑菌浓度(AUC_(0-24h)/MIC)指数。结果研究纳入的患儿年龄中位数为3.60(1.20,20.00)月龄,万古霉素给药日剂量中位数为39.23(30.00,46.51)mg/kg,血药谷浓度中位数为3.30(1.50,7.10)mg/L,在5~15 mg/L范围的达标率为26.4%(23/87)。AUC_(0-24h)中位数为213(174,293)mg·h/L,AUC_(0-24h)/MIC中位数为221(128,349),其中日剂量>60 mg/kg患儿AUC_(0-24h)中位数≥400 mg·h/L、AUC_(0-24h)/MIC中位数≥400,对应年龄中位数为28.50(6.85,36.00)月龄。多因素logistic分析显示谷浓度与AUC_(0-24h)具有较好的相关性(P=0.002)。所有患儿在治疗结束时临床有效率85.1%(74/87),细菌学清除率95.4%(83/87),治疗过程中无肾功能损伤发生。结论纳入患儿万古霉素给药日剂量、血药谷浓度、AUC_(0-24h)/MIC中位数均低于国内外推荐范围,但万古霉素低暴露量下儿童患者仍具有较好的临床和微生物学疗效。当万古霉素日剂量>60 mg/kg(对应年龄中位数28.50月龄)或Cmin≥5 mg/L时,AUC_(0-24h)≥400 mg·h/L及AUC_(0-24h)/MIC≥400的达标率增加。

关键词：万古霉素治疗药物监测药物浓度儿童疗效