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Use of artificial intelligence in the field of pain medicine

World Journal of Clinical Cases 2024年第2期12卷 236-239页

作者： Min Cheol chang Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaegu 705-717South Korea

In this editorial we comment on the article“Potential and limitations of ChatGPT and generative artificial intelligence in medial safety education”published in the recent issue of the World Journal of Clinical *** article described the usefulness of artificial intelligence(AI)in medial safety ***,we focus specifically on the use of AI in the field of pain *** technology has emerged as a powerful tool,and is expected to play an important role in the healthcare sector and significantly contribute to pain medicine as further developments are *** may have several applications in pain ***,AI can assist in selecting testing methods to identify causes of pain and improve diagnostic *** of a patient’s symptoms into the algorithm can prompt it to suggest necessary tests and possible *** on the latest medical information and recent research results,AI can support doctors in making accurate diagnoses and setting up an effective treatment ***,AI assists in interpreting medical *** neural and musculoskeletal disorders,imaging tests are of vital *** can analyze a variety of imaging data,including that from radiography,computed tomography,and magnetic resonance imaging,to identify specific patterns,allowing quick and accurate image ***,AI can predict the outcomes of pain treatments,contributing to setting up the optimal treatment *** predicting individual patient responses to treatment,AI algorithms can assist doctors in establishing a treatment plan tailored to each patient,further enhancing treatment *** efficient utilization of AI in the pain medicine field,it is crucial to enhance the accuracy of AI decision-making by using more medical data,while issues related to the protection of patient personal information and responsibility for AI decisions will have to be *** the future,AI technology is expected to be innovatively applied in the field of

关键词： Artificial intelligence Pain medicine Diagnosis Prediction Image

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Chronic venous insufficiency, could it be one of the missing pieces in the puzzle of treating pain?

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World Journal of Clinical Cases 2024年第1期12卷 232-235页

作者： Min Cheol chang Department of Physical Medicine and Rehabilitation Yeungnam University HospitalDaegu 705-717South Korea

Pain is a common complaint among patients seeking medical *** left un-treated,pain can become chronic,significantly affecting patients’quality of *** accurate diagnosis of the underlying cause of pain is crucial for effective *** venous insufficiency(CVI)is frequently overlooked by pain ***,many pain physicians lack sufficient knowledge about *** is a common condition resulting from malfunctioning or damaged valves in lower limb *** of CVI,ranging from mild to severe,include pain,heaviness,fatigue,itching,swelling,skin color changes,and ulcers in the lower ***,it has become more widely known that these symptoms can be attributed to *** slight or mild CVI can cause related *** physicians primarily consider neuromusculoskeletal disorders when assessing patients with leg pain,and often neglect the possibility of *** clinical practice,when pain physicians encounter patients with unresolved leg pain,they must assess whether the patients exhibit symptoms of CVI and conduct tests to differ-entiate CVI from other potential causes.

关键词： Pain Chronic venous insufficiency Diagnosis Treatment Vein

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Palladium-catalyzed multi components oxy-aminofluorination and aminofluorination of gem-difluoroalkenes

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Chinese Chemical Letters 2024年第2期35卷 420-425页

作者： Fen Wu Xin Li Junbiao chang Dachang Bai State Key Laboratory of Antiviral Drugs NMPA Key Laboratory for Research and Evaluation of Innovative DrugKey Laboratory of Green Chemical Media and ReactionsMinistry of EducationSchool of Chemistry and Chemical EngineeringPingyuan LaboratoryHenan Normal UniversityXinxiang 453007China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

Organofluorine compounds are widely used in the realm of drug discovery and material ***,we developed palladium catalyzed intermolecular aminofluorination and oxy-aminofluorination of gem‑difluoroalkenes with N-fluorobenzenesulfonimide(NFSI),in which NFSI was used as the nitrogen source and *** reaction provides an efficient and straightforward synthesis route of a series ofα-trifluoromethyl benzylic ***,three/four components oxy-aminofluorination processes were realized to giveα-trifluoromethyl benzylic ether with a terminal amino group,which proceed through C(sp^(3))-O bond cleavage of easily available ether and simultaneous introduced a fluorine,an amino and an oxy substituent in one pot with excellent *** divergent reactivity not only included the incorporation of one ether molecular,but also much more challenged two ether insertion with excellent selectivity through succession C(sp^(3))-O bonds *** protocol allows for concise synthesis of high value amines with fluoroalkyl-substituents and selectively transformation of easily available ethers by high-valent palladium catalysis.

关键词： Palladium Multi components Aminofluorination Oxy-aminofluorination C(sp^(3))-O bond cleavage

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Energy-efficient reconfigurable processor for QC-LDPC via adaptive coding-voltage-frequency tuning

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The Journal of China Universities of Posts and Telecommunications 2024年第2期31卷 72-84页

作者： chang Libo Hu Yiqing Du Huimin Wang Jihe School of Electronic Engineering Xi'an University of Posts and TelecommunicationsXi'an 710121China School of Computer Science Northwestern Polytechnical UniversityXi'an 710072China

To apply a quasi-cyclic low density parity check(QC-LDPC)to different scenarios,a data-stream driven pipelined macro instruction set and a reconfigurable processor architecture are proposed for the typical QC-LDPC *** data-level parallelism is improved by instructions to dynamically configure the multi-core computing ***,an intelligent adjustment strategy based on a programmable wake-up controller(WuC)is designed so that the computing mode,operating voltage,and frequency of the QC-LDPC algorithm can be *** adjustment can improve the computing efficiency of the *** QC-LDPC processors are verified on the Xilinx ZCU102 field programmable gate array(FPGA)board and the computing efficiency is *** experimental results indicate that the QC-LDPC processor can support two encoding lengths of three typical QC-LDPC algorithms and 20 adaptive operating modes of operating voltage and *** maximum efficiency can reach up to 12.18 Gbit/(s·W),which is more flexible than existing state-of-the-art processors for QC-LDPC.

关键词： quasi-cyclic low density parity check(QC-LDPC) dynamic voltage and frequency scaling(DVFS) reconfigurable computing coarse-grained reconfigurable arrays(CGRAs)

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Advances in the study of auxin early response genes:Aux/IAA,GH3,and SAUR

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The Crop Journal 2024年第4期12卷 964-978页

作者： Dongfang Bao Senqiu chang Xiaodong Li Yanhua Qi Key Laboratory of Herbage&Endemic Crop Biology of Ministry of Education Inner Mongolia Key Laboratory of Herbage&Endemic Crop BiotechnologySchool of Life SciencesInner Mongolia UniversityHohhot 010000Inner MongoliaChina

Auxin plays a crucial role in all aspects of plant growth and *** can induce the rapid and efficient expression of some genes,which are named auxin early response genes(AERGs),mainly including the three families:auxin/indole-3-acetic acid(Aux/IAA),Gretchen Hagen 3(GH3),and small auxin-up RNA(SAUR).Aux/IAA encodes the Aux/IAA protein,which is a negative regulator of auxin ***/IAA and auxin response factor(ARF)form a heterodimer and participate in a variety of physiological processes through classical or non-classical auxin signaling *** GH3 encodes auxin amide synthetase,which catalyzes the binding of auxin to acyl-containing small molecule substrates(such as amino acids and jasmonic acid),and regulates plant growth and stresses by regulating auxin *** is a class of small auxin up-regulated *** response to auxin is complex,and the process may occur at the transcriptional,post-transcriptional and protein *** the development of multi-omics,significant progress has been made in the study of Aux/IAA,GH3,and SAUR genes,but there are still many *** review offers insight into the characteristics of Aux/IAA,GH3,and SAUR gene families,and their roles in roots,hypocotyls,leaves,leaf inclinations,flowers,seed development,stress response,and phytohormone crosstalk,and provides clues for future research on phytohormone signaling and the molecular design breeding of crops.

关键词： Auxin Aux/IAA GH3 SAUR Stress

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Controlled Synthesis of Metal-Nanoparticles Decorated Block Copolymer Hybrid Particles via Emulsion Confined Self-assembly and Their Catalytic Applications

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Chinese Journal of Chemistry 2024年第8期42卷 835-840页

作者： Xiaohua chang Qunli Yu Dan Ji Yutian Zhu College of Material Chemistry and Chemical EngineeringKey Laboratory of Organosilicon Chemistry and Material TechnologyMinistry of EducationHangzhou Normal UniversityHangzhouZhejiang311121 China

Comprehensive Summary Metal nanoparticles(NPs)decorated block copolymer(BCP)hybrid nanoparticles have attracted enormous attention for their actual value in catalysis,medical therapy,and *** confined assembly of BCPs within evaporative emulsion droplet is verified as an effective method to provide polymeric scaffolds to load metal ***,to date,it remains challenging to generate different types of metal NPs decorated BCP hybrid ***,we employed the emulsion confined self-assembly of poly(styrene-b-2-vinylpyridine)(PS-b-P2VP)and the followed seed-mediated growth of Au and palladium(Pd)NPs onto well-defined BCP particles to design a series of Au/Pd decorated BCP hybrid nanoparticles,which exhibited excellent catalytic activity for the reduction of 4-nitrophenol to 4-aminophenol with the reductant of *** work may inspire more researchers to investigate the selective decoration of different metal NPs onto the polymeric scaffolds,broadening the potential applications of the inorganic/organic hybrid nanoparticles.

关键词： Block copolymers Emulsion confined self-assembly Hybrid nanoparticles Catalytic activity Recyclability

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电流密度对含Ca和P镁合金微弧氧化膜性能的影响

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兵器材料科学与工程 2013年第4期36卷 33-37页

作者：刘伟常立民段小月徐丹丹吉林师范大学环境科学与工程学院吉林四平136000 吉林师范大学化学学院吉林四平136000

在含有EDTA-Ca和Na2HPO4的电解液中,以恒电流方式制备富含Ca和P的镁合金微弧氧化陶瓷膜,研究电流密度对陶瓷膜结构及耐蚀性的影响。利用涂层测厚仪、X-射线荧光光谱仪(XRF)、X-射线衍射仪(XRD)、扫描电子显微镜(SEM)及电化学工作站对陶... 详细信息

在含有EDTA-Ca和Na2HPO4的电解液中,以恒电流方式制备富含Ca和P的镁合金微弧氧化陶瓷膜,研究电流密度对陶瓷膜结构及耐蚀性的影响。利用涂层测厚仪、X-射线荧光光谱仪(XRF)、X-射线衍射仪(XRD)、扫描电子显微镜(SEM)及电化学工作站对陶瓷膜厚度、元素组成、相组成、表面形貌及膜层在Hank溶液中的耐蚀性进行了测试。结果表明:随着电流密度的增加,膜层的厚度及Ca/P均呈现先增加后减小的趋势;膜层主要由MgO及MgAl2O4组成,膜层中的Ca,P以非晶形式存在;陶瓷膜均呈现典型的微弧氧化形貌,随着电流密度的增加,孔径逐渐增大,分布逐渐趋于不均匀,甚至出现裂痕;电流密度为100 mA/cm2,MgAl2O4含量最高,膜层的耐蚀性最佳。

关键词：镁合金微弧氧化电流密度 Ca和P 耐蚀性

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Low carbon alcohol fuel electrolysis of hydrogen generation catalyzed by a novel and effective Pt–CoTe/C bifunctional catalyst system

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Green Energy & Environment 2024年第4期9卷 758-770页

作者： Yang Zhou Lice Yu Jinfa chang Ligang Feng Jiujun Zhang School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou225002JiangsuChina NanoScience Technology Center University of Central FloridaOrlandoFL32826USA College of Sciences&Institute for Sustainable Energy Shanghai UniversityShanghai200444China

Low carbon alcohol fuels electrolysis under ambient conditions is promising for green hydrogen generation instead of the traditional alcohol fuels steam reforming technique,and highly efficient bifunctional catalysts for membrane electrode fabrication are required to drive the electrolysis ***,the efficient catalytic promotion effect of a novel catalyst promoter,CoTe,on Pt is demonstrated for low carbon alcohol fuels of methanol and ethanol electrolysis for hydrogen *** and density functional theory calculation results indicate that the optimized electronic structure of Pt–CoTe/C resulting from the synergetic effect between Pt and CoTe further regulates the adsorption energies of CO and H*that enhances the catalytic ability for methanol and ethanol ***,the good water activation ability of CoTe and the strong electronic effect of Pt and CoTe increased the tolerance ability to the poisoning species as demonstrated by the CO-stripping *** high catalytic kinetics and stability,as well as the promotion effect,were also carefully ***,71.9%and 75.5%of the initial peak current density was maintained after 1000 CV cycles in acid electrolyte for methanol and ethanol oxidation;and a low overpotential of 30 and 35 mV was required to drive the hydrogen evolution reaction in methanol and ethanol solution at the current density of 10 mA cm^(-2).In the two-electrode system for alcohol fuels electrolysis,using the optimal Pt–CoTe/C catalyst as bi-functional catalysts,the cell potential of 0.66 V(0.67 V)was required to achieve 10 mA cm^(-2) for methanol(ethanol)electrolysis,much smaller than that of water electrolysis(1.76 V).The current study offers a novel platform for hydrogen generation via low carbon alcohol fuel electrolysis,and the result is helpful to the catalysis mechanism understanding of Pt assisted by the novel promoter.

关键词： Methanol electrolysis Ethanol electrolysis Cobalt telluride Pt-based electrocatalyst Hydrogen evolution reaction

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A comprehensive research on wear resistance of GH4169 superalloy in longitudinal-torsional ultrasonic vibration side milling with tool wear and surface quality

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Chinese Journal of Aeronautics 2024年第4期37卷 556-573页

作者： Baoqi chang Zhaoxi YI Fen ZHANG Lian DUAN Ji-an DUAN School of Mechanical and Electrical Engineering Central South UniversityChangsha 410083China State Key Laboratory of High Performance and Complex Manufacturing Central South UniversityChangsha 410083China School of Physics and Electronics Central South UniversityChangsha 410083China

To improve the service and machining performance of the workpiece, the tool wear mechanisms, surface machining quality, and wear resistance in conventional side milling(CSM)and longitudinal-torsional ultrasonic vibration side milling(LTUVSM) of GH4169 superalloy at different cutting lengths are investigated systematically. Tool wear mechanisms are revealed and the correlation between machined surface quality with tool wear is analyzed correspondingly. Tool wear patterns mainly include adhesive wear, diffusion wear, abrasive wear, and chipping *** surface quality is achieved in LTUVSM due to a maximum reduction of flank wear bandwidth and wear rate by 71.9% and 71.5%, respectively, compared to CSM. The friction coefficient,initial wear stage time, and wear volume of dry sliding wear were measured to evaluate the workpiece wear resistance. The maximum reductions in friction coefficient and wear volume in LTUVSM are 18.2% and 15.8% compared to CSM. The regular ultrasonic vibration textures suppress the friction and the growth of contact nodes in the contact area, decreasing the degree of surface wear, which is demonstrated by a 38.8% increase in initial wear stage time compared to *** conclusion, the workpiece in LTUVSM exhibits higher wear resistance because of the improvement of tool wear and the guarantee of surface quality.

关键词： Dry sliding wear Surface quality Tool wear Ultrasonic vibration Wear resistance

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Ionic Liquid-Enhanced Assembly of Nanomaterials for Highly Stable Flexible Transparent Electrodes

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Nano-Micro Letters 2024年第7期16卷 441-455页

作者： Jianmin Yang Li chang Xiqi Zhang Ziquan Cao Lei Jiang Key Laboratory of Bio-Inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China College of Chemistry and Chemical Engineering Chongqing University of TechnologyChongqing 400054People’s Republic of China Binzhou Institute of Technology Binzhou 256600People’s Republic of China Nanomics Biotechnology Co. Ltd.HangzhouPeople’s Republic of China

The controlled assembly of nanomaterials has demon-strated significant potential in advancing technological ***,achieving highly efficient and low-loss assembly technique for nanomate-rials,enabling the creation of hierarchical structures with distinctive func-tionalities,remains a formidable ***,we present a method for nanomaterial assembly enhanced by ionic liquids,which enables the fabrication of highly stable,flexible,and transparent electrodes featuring an organized layered *** utilization of hydrophobic and non-volatile ionic liquids facilitates the production of stable interfaces with water,effectively preventing the sedimentation of 1D/2D nanomaterials assembled at the ***,the interfacially assembled nanomaterial monolayer exhibits an alternate self-climbing behavior,enabling layer-by-layer transfer and the formation of a well-ordered MXene-wrapped silver nanowire network *** resulting composite film not only demonstrates exceptional photoelectric performance with a sheet resistance of 9.4Ωsq^(-1) and 93%transmittance,but also showcases remarkable environmental stability and mechanical *** noteworthy is its application in transparent electromagnetic interference shielding materials and triboelectric nanogenerator *** research introduces an innovative approach to manufacture and tailor functional devices based on ordered nanomaterials.

关键词： Ionic liquids Assembly Silver nanowires MXene nanosheets Flexible transparent electrodes

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