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Prostate magnetic resonance imaging and the value of experience:An intrareader variability study

Asian Journal of Urology 2023年第4期10卷 488-493页

作者： Thomas Whish-Wilson Jo-Lynn Tan William Cross lih-ming wong Tom Sutherland Department of Surgery St Vincent's Hospital Melbourne41 Victoria PdeFitzroy VICAustralia Department of Surgery The University of MelbourneMelbourne VICAustralia Faculty of Medicine The University of MelbourneMelbourne VICAustralia Medical Imaging Department St Vincent's Hospital Melbourne41 Victoria PdeFitzroy VICAustralia

Objective To measure the intraobserver concordance of an experienced genitourinary radiologist reporting of multiparametric magnetic resonance imaging of the prostate(mpMRIp)scans over *** An experienced genitourinary radiologist re-reported his original 100 consecutive mpMRIp scans using Prostate Imaging-Reporting and Data System version 2(PI-RADS v2)after 5 years of further experience comprising>1000 *** agreement was measured using Cohen's ***,specificity,negative predictive value(NPV),positive predictive value(PPV),and accuracy were calculated,and comparison of sensitivity was performed using McNemar's *** Ninety-six mpMRIp scans were included in our final *** the 96 patients,53(55.2%)patients underwent subsequent biopsy(n=43)or prostatectomy(n=15),with 73 lesions *** agreement(Cohen's kappa 0.55)was seen in the number of lesions identified at initial reporting and on re-reading(81 vs.39 total lesions;and 71 vs.37 number of PI-RADS≥3 lesions).For clinically significant prostate cancer,re-reading demonstrated an increase in specificity(from 43%to 89%)and PPV(from 62%to 87%),but a decrease in sensitivity(from 94%to 72%,p=0.01)and NPV(from 89%to 77%).Conclusion The intraobserver agreement for a novice to experienced radiologist reporting mpMRIp using PI-RADS v2 is *** sensitivity is off-set by improved specificity and PPV,which validate mpMRIp as a gold standard for prebiopsy screening.

关键词： Prostate cancer Magneticresonance imaging Prostate Imaging-Reporting and Data System Intrareader Prostate biopsy

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Deep residual learning for denoising Monte Carlo renderings

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Computational Visual Media 2019年第3期5卷 239-255页

作者： Kin-ming wong Tien-Tsin wong Artixels Hong Kong S.A.R.China Department of Computer Science and Engineering the Chinese University of Hong KongHong Kong S.A.R.China

Learning-based techniques have recently been shown to be effective for denoising Monte Carlo rendering methods. However, there remains a quality gap to state-of-the-art handcrafted denoisers. In this paper, we propose a deep residual learning based method that outperforms both state-of-the-art handcrafted denoisers and learning-based *** the indirect nature of existing learning-based methods(which e.g., estimate the parameters and kernel weights of an explicit feature based filter), we directly map the noisy input pixels to the smoothed output. Using this direct mapping formulation, we demonstrate that even a simple-and-standard ResNet and three common auxiliary features(depth, normal,and albedo) are sufficient to achieve high-quality denoising. This minimal requirement on auxiliary data simplifies both training and integration of our method into most production rendering pipelines. We have evaluated our method on unseen images created by a different renderer. Consistently superior quality denoising is obtained in all cases.

关键词： Monte Carlo rendering denoising deep learning deep residual learning filter-free denoising

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The electroweak monopole–antimonopole pair in the standard model

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Communications in Theoretical Physics 2024年第3期76卷 113-119页

作者： Dan Zhu Khai-ming wong Guo-Quan wong School of Physics Universiti Sains Malaysia11800 USMPenangMalaysia

We present the first numerical solution that corresponds to a pair of Cho–Maison monopoles and antimonopoles(MAPs) in the SU(2) × U(1) Weinberg–Salam(WS) *** monopoles are finitely separated,while each pole carries a magnetic charge ±4π/*** positive pole is situated in the upper hemisphere,whereas the negative pole is in the lower *** Cho–Maison MAP is investigated for a range of Weinberg angles,0.4675≤ tan θ_(W)≤10,and Higgs self-coupling,0 ≤ β ≤ *** magnetic dipole moment(μm) and pole separation(d_(z)) of the numerical solutions are calculated and *** total energy of the system,however,is infinite due to point singularities at the locations of monopoles.

关键词： magnetic monopole Cho-Maison monopole Weinberg-Salam model

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Airborne transmission during short-term events: Direct route over indirect route

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Building Simulation 2022年第12期15卷 2097-2110页

作者： Xiujie Li Zhengtao Ai Jinjun Ye Cheuk ming Mak Hai ming wong Department of Building Environment and Energy Engineering The Hong Kong Polytechnic UniversityHong KongChina Department of Civil Engineering Hunan UniversityChangshaChina National Center for International Research Collaboration in Building Safety and Environment Hunan UniversityChangshaChina Faculty of Dentistry The University of Hong KongHong KongChina

Numerous short-term exposure events in public spaces were reported during the COVID-19 pandemic,especially during the spread of Delta and ***,the currently used exposure risk assessment models and mitigation measures are mostly based on the assumption of steady-state and complete-mixing *** present study investigates the dynamics of airborne transmission in short-term events when a steady state is not reached before the end of the ***-eddy simulation(LES)is performed to predict the airborne transmission in short-term events,and three representative physical distances between two occupants are *** time-averaged and phase-averaged exposure indices are used to evaluate the exposure *** results present that the exposure index in the short-term events constantly varies over time,especially within the first 1/ACH(air changes per hour)hour of exposure between occupants in close proximity,posing high uncertainty to the spatial and temporal evolutions of the risk of *** decoupling analysis of the direct and indirect airborne transmission routes indicates that the direct airborne transmission is the predominated route in short-term *** suggests also that the general dilution ventilation has a relatively limited efficiency in mitigating the risk of direct airborne transmission,but determines largely the occurrence time of the indirect *** the randomness,discreteness,localization,and high-risk characteristics of direct airborne transmission,a localized method that has a direct interference on the respiratory flows would be better than dilution ventilation for short-term events,in terms of both efficiency and cost.

关键词： airborne transmission short-term events direct exposure transient computational fluid dynamics(CFD) exposure risk

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Development and accuracy of artificial intelligence-generated prediction of facial changes in orthodontic treatment:a scoping review

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第11期24卷 974-984页

作者： Jiajun ZHU Yuxin YANG Hai ming wong Stomatology Hospital School of StomatologyZhejiang University School of MedicineZhejiang Provincial Clinical Research Center for Oral DiseasesKey Laboratory of Oral Biomedical Research of Zhejiang ProvinceCancer Center of Zhejiang UniversityEngineering Research Center of Oral Biomaterials and Devices of Zhejiang ProvinceHangzhou310000China Faculty of Dentistry The University of Hong KongHong KongChina

Artificial intelligence(AI)has been utilized in soft-tissue analysis and prediction in orthodontic treatment planning,although its reliability has not been systematically *** scoping review was conducted to outline the development of AI in terms of predicting soft-tissue changes after orthodontic treatment,as well as to comprehensively evaluate its prediction *** electronic databases(PubMed,EBSCOhost,Web of Science,Embase,Cochrane Library,and Scopus)were searched up to March 14,*** studies investigating the performance of AI-based systems in predicting post-orthodontic soft-tissue alterations were *** Quality Assessment of Diagnostic Accuracy Studies-2(QUADAS-2)and Joanna Briggs Institute(JBI)appraisal checklist for diagnostic test accuracy studies were applied to assess risk of bias,while the Grading of Recommendation,Assessment,Development,and Evaluation(GRADE)assessment was conducted to evaluate the certainty of *** screening 2500 studies,four non-randomized clinical trials were finally included for full-text *** found a low level of evidence indicating an estimated high overall accuracy of AI-generated prediction,whereas the lower lip and chin seemed to be the least predictable ***,the facial morphology simulated by AI via the fusion of multimodality images was considered to be reasonably *** all of the included studies that were not randomized clinical trials(non-RCTs)showed a moderate to high risk of bias,more well-designed clinical trials with sufficient sample size are needed in future work.

关键词： Facial morphology Soft-tissue changes Artificial intelligence(AI) Orthodontic treatment

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Biomechanical comparison of locking plate and crossing metallic and absorbable screws fixations for intra-articular calcaneal fractures

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Science China(Life Sciences) 2016年第9期59卷 958-964页

作者： ming Ni Duo Wai-Chi wong Jiong Mei Wenxin Niu ming Zhang Tongji Hospital Tongji University School of Medicine Shanghai 200065 China Pudong New Area People's Hospital Shanghai 201299 China Interdisciplinary Division of Biomedical Engineering The Hong Kong Polytechnic University Hong Kong SAR China Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center) Shanghai 201619 China

The locking plate and percutaneous crossing metallic screws and crossing absorbable screws have been used clinically to treat intra-articular calcaneal fractures, but little is known about the biomechanical differences between them. This study compared the biomechanical stability of calcaneal fractures fixed using a locking plate and crossing screws. Three-dimensional finite-element models of intact and fractured calcanei were developed based on the CT images of a cadaveric sample. Surgeries were simulated on models of Sanders type III calcaneal fractures to produce accurate postoperative models fixed by the three implants. A vertical force was applied to the superior surface of the subtalar joint to simulate the stance phase of a walking gait. This model was validated by an in vitro experiment using the same calcaneal sample. The intact calcaneus showed greater stiffness than the fixation models. Of the three fixations, the locking plate produced the greatest stiffness and the highest von Mises stress peak. The micromotion of the fracture fixated with the locking plate was similar to that of the fracture fixated with the metallic screws but smaller than that fixated with the absorbable screws. Fixation with both plate and crossing screws can be used to treat intra-articular calcaneal fractures. In general, fixation with crossing metallic screws is preferable because it provides sufficient stability with less stress shielding.

关键词： finite-element analysis in vitro experiment calcaneal fracture plate fixation absorbable screw biomechanics

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Effect of Earthworm(Pheretimasp.) Density on Revegetation of Lead/zinc Metal Mine Tailings Amended with Soil

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Chinese Journal of Population,Resources and Environment 2008年第2期6卷 43-48页

作者： Cheng Jiemin ming H wong College of Population Resources and Environment Shandong Normal University Jinan Shandong 210014 China Croucher Institute for Environmental Sciences Department of Biology Hong Kong Baptist University Hong Kong China

The objective of this study was to investigate the ef- fects of earthworm density on the availability of nutrients and heavy metals in metal contaminated ***/Zn mine tailings were mixed throughly with a red yellow podzolic soil at the ratio (w/w) of 75:*** (Pheretima sp.) were introduced to the mixture at four different densities,zero,three,six and nine individuals per pot planted with ryegrass (Loliun multiflorum). The results indicated that earthworm activity significantly en- hanced ryegrass shoot ***,as denser earthworm population was introduced,shoot biomass tended to decrease. Earthworm activity significantly increased soil pH and availability of N,P and K in the tailings and soil *** was a general tendency that uptake of Zn by ryegrass increased after earthworm inoculation,although the increase in extractable Zn in tailings and soil mixture was not *** the contrary,there seemed to be a lower uptake of Pb by ryegrass under earthworm inoclation, despite the fact that higher extractable Pb concentrations were *** present project indicated that the improved growth of ryegrass was due to improved nutrient availability and other soil conditions,by inoculation of earthworms at an appropriate *** studies are needed to illustrate the relationship be- tween metal availability and earthworm activity in the field.

关键词： lead zinc nitrogen phosphorus phytostabilization Pb/Zn mine tailings

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Optimization of control parameters for petroleum waste composting

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Journal of Environmental Sciences 2001年第4期13卷 385-390页

作者： MA Ying ZHANG Jia yao wong ming Hung WU Wen zhong Department of Biology and Institute for Natural Resource and Waste Management Hong Kong Baptist UniversityKowloon TongHong KongChina Department of Environmental Science Wuhan UniversityWuhan 430072China State Key Laboratory for Freshwater Ecology and Biotechnology Institute of HydrobiologyChinese Academy of SciencesWuhan 430072China

Composting is being widely employed in the treatment of petroleum waste. The purpose of this study was to find the optimum control parameters for petroleum waste in-vessel composting. Various physical and chemical parameters were monitored to evaluate their influence on the microbial communities present in composting. The CO2 evolution and the number of microorganisms were measured as the activity of composting. The results demonstrated that the optimum temperature, pH and moisture content were 56.5 - 59.5 degreesC, 7.0 - 8.5 and 55 % - 60%, respectively. Under the optimum conditions, the removal efficiency of petroleum hydrocarbon reached 83.29% after 30 days composting.

关键词： optimization control parameters petroleum waste composting

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Evolutionary Mode of Metallothioneins Inferred from Cd-MT Genes of Tetrahymena

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Wuhan University Journal of Natural Sciences 2005年第5期10卷 925-930页

作者： WAN ming-liang FENG Wei-song MIAO Wei wong ming-hong State Key Laboratory of Freshwater Ecology and Biotechnology Institute of Hydrobiology Chinese Academyof Sciences Wuhan 430072 Hubei China Institute for Natural Resources and Environmental Management Hong Kong Baptist University Kowloon Tong Hong Kong China

From Tetrahymena thermophila （strain BF5）, the coding region of Cd-MT gene was cloned and sequenced. and identified as MTT1 isoform. A serial duplicate structure is discovered in its amino acid sequence, which separates the coding region into three parts （Part 1：7-61; Part 2：64-118; Part 3：122-162）. The alignments among them and comparison with the corresponding parts of MT1 isoform suggest that MT1 and MTT1 isoforms both come from the same ancient gene that is homologous to Part 1, and Cd-MTs of Tetrahymena are aroused by such ancient gene duplication. The prediction of secondary structures and the analysis of the disulfide-bonding state of cysteine show that there are a lot of differences between MT1 and MTT1 isoforms, which maybe relate to their function mechanism.

关键词： Tetrahymena tkermopkila metallothioneins evolutionary mode gene duplication protein spatial structure metal-binding sites

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Monolithic full-color active-matrix micro-LED microdisplay using InGaN/AlGaInP heterogeneous integration

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Light(Science & Applications) 2023年第11期12卷 2459-2467页

作者： Longheng Qi Peian Li Xu Zhang Ka ming wong Kei May Lau Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

A prototype of full-color active-matrix micro-light-emitting diode(micro-LED)micro-display with a pixel density of 391 pixel per inch(ppi)using InGaN/AlGaInP heterogeneous integration is *** blue/green dual-color micro-LED arrays realized on a single metal organic chemical vapor deposition(MOCVD)-grown GaN-on-Si epiwafer and AlGaInP red micro-LED arrays are both monolithically fabricated,followed by the integration with a common complementary metal oxide semiconductor(CMOS)backplane via flip-chip bonding technology to form a doublelayer thin-film display ***-color images with decent color gamut and brightness are successfully displayed through the fine adjustment of driving current densities of RGB *** full-color display combines the advantages of high quantum efficiency of InGaN material on blue/green light and AlGaInP material on red light through heterogeneous integration and high pixel density through monolithic fabrication approach,demonstrating the feasibility and prospects of high brightness,good color performance,and high-resolution micro-LED microdisplays in future metaverse applications.

关键词： AlGaInP integration matrix

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