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A MIXED FINITE ELEMENT METHOD FOR THE CONTACT PROBLEM IN ELASTICITY

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Journal of Computational Mathematics 2005年第4期23卷 441-448页

作者： Dong-ying Hua lie-heng wang ICMSEC Academy of Mathematics and System Sciences Chinese Academy of Sciences Beijing 100080 China Graduate School of the Chinese Academy of Science Beijing 100080 China LSEC ICMSEC Academy of Mathematics and System Sciences Chinese Academy of Sciences Beijing 100080 China

Based on the analysis of [7] and [10], we present the mixed finite element approximation of the variational inequality resulting from the contact problem in elasticity. The convergence rate of the stress and displacement field are both improved from O（h3/4） to quasi-optimal O（h│logh│^1/4）. If stronger but reasonable regularity is available, the convergence rate can be optimal O（h）.

关键词： Contact problem Mixed finite element method

Quantitative conditions for time evolution in terms of the von Neumann equation

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Science China(Physics,Mechanics & Astronomy) 2018年第7期61卷 54-60页

作者： WenHua wang HuaiXin Cao ZhengLi Chen lie wang School of Ethnic Education Shaanxi Normal University Xi'an 710062 China School of Mathematics and In Cbrmatton Sctence Shaanxi Normal University Xi 'an 710062 China

The adiabatic theorem describes the time evolution of the pure state and gives an adiabatic approximate solution to the Schrrdinger equation by choosing a single eigenstate of the Hamiltonian as the initial state. In quantum systems, states are divided into pure states （unite vectors） and mixed states （density matrices, i.e., positive operators with trace one）. Accordingly, mixed states have their own corresponding time evolution, which is described by the von Neumann equation. In this paper, we discuss the quantitative conditions for the time evolution of mixed states in terms of the von Neumann equation. First, we introduce the definitions for uniformly slowly evolving and δ-uniformly slowly evolving with respect to mixed states, then we present a necessary and sufficient condition for the Hamiltonian of the system to be uniformly slowly evolving and we obtain some upper bounds for the adiabatic approximate error. Lastly, we illustrate our results in an example.

关键词： quantitative condition time evolution uniformly slowly evolving δ-uniformly slowly evolving upper bound

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Batteries for wearables

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National Science Review 2023年第1期10卷 9-11页

作者： lie wang Ye Zhang Peter G.Bruce National Laboratory of Solid State Microstructures Jiangsu Key Laboratory of Artificial Functional Materials Chemistry and Biomedicine Innovation Center (Chem BIC) Collaborative Innovation Center of Advanced Microstructures College of Engineering and Applied Sciences Nanjing University Departments of Materials and Chemistry University of Oxford

Batteries that convert the stored chemical energy directly into electricity have been known for hundreds of *** the lithium-ion battery as representative because of its high energy-conversion efficiency and long cycle *** is widely used as a power accessory for electronic devices and has become an important part of modern electronics.

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Transcriptional regulation of the immune checkpoints PD-1 and CTLA-4

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Cellular & Molecular Immunology 2022年第7期19卷 861-862页

作者： Jing Guo Zhonghui Xue lie wang Institute of Immunology and Bone Marrow Transplantation Center The First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang310006China Department of Microbiology and Immunology Stanford University School of MedicineStanfordCA94305USA Research Center of Clinical Medicine Affiliated Hospital of Nantong UniversityNantongJiangsu226001China Liangzhu Laboratory Zhejiang University Medical CenterHangzhouZhejiang311121China

Immunotherapy targeting immune checkpoints(ICs)has revolutionized the field of cancer *** are a group of proteins that provide stimulatory or inhibitory signals to regulate T-cell activation,tolerance,and *** date,some immune checkpoint inhibitors(ICIs)targeting TIM-3,LAG-3,TIGIT,and VISTA are under investigation for their clinical ***,only ICIs against CTLA-4,PD-1,and PD-L1 are approved by the FDA and widely used as first-line or second-line treatments for multiple cancer ***-4 and PD-1 are coinhibitory receptors that are mainly expressed by T cells.

关键词： immune cancer clinical

ON THE ORIGIN OF TURBULENT SECONDARY FLOW IN A STRAIGHT DUCT OF NON-CIRCULAR CROSS-SECTION

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Journal of Hydrodynamics 1993年第3期5卷 98-111页

作者： Zhao, lie wang, Famin Bian, Yungui Yu, Xin Inst of Mechanics Academia Sinica Beijing China

The origin of turbulent secondary flow in a straight duct of non-circular cross-section was discussed from a theoretical standpoint and examined from a numerical simulation of the turbulent flow in a square duct. It was reached that the driving force of such secondary flow comes from the second-order terms of the difference in gradients of normal and transverse Reynolds stresses in the axial vorticity equation. The present results obtained compare well with available experimental results for both primary and secondary flow quantities.

关键词： Ducts Pipe flow Simulation

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Endopeptidase Isoenzyme Characteristics in Cucumis sativus Leaves During Dark-induced Senescence

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Journal of Integrative Plant Biology 2007年第4期49卷 507-514页

作者： Peng Zhang Fei wang lie-Feng Zhang Qi Rui Lang-Lai Xu College of Life Sciences Nanjing Agricultural University Nanjing 210095 China

The changes and characteristics of endopeptidase （EP） isoenzymes in cucumber （Cucumis sativus L.） leaves during dark-induced senescence were investigated by activity staining after gradient-polyacrylamide gel electrophoresis （G-PAGE） containing co-polymerized gelatin as substrate. The results showed that both the chlorophyll and the protein contents of leaves were decreased, and the protein degradation was correlated with the increase of proteolytic activity during the course of leaf senescence. Meanwhile, nine cucumber endopeptidases isoenzymes （CEP） with 140, 120, 106, 94, 76, 55, 46, 39 and 35 kDa molecular weights were detected. Four of these, CEP2, 3, 4 and CEP9 appeared all the time, but the changes of the activity were different during incubation. Another four CEPs （CEP5, 6, 7 and CEP8） whose activities increased with dark-induced time were only detected in senescent leaves. Furthermore, the biochemical properties of these nine CEP were also characterized. All the CEPs had high activities from 35 ℃ to 45 ℃, and the optimum temperature was found to be 40 ℃. However, the activities of CEPs were not detected below 25 ℃ or over 60 ℃. The activity bands appeared at a wide range of pH from 5.0 to 9.0, but the optimum pH was found at 7.0. No CEPs were detected at pH 4 or pH 10. By inhibition analysis we concluded that CEP2, 3, 4 and CEP9 were serine endopeptidases and CEP6 was a kind of cysteine protease. It is suggested that serine endopeptidases might play a major role in cucumber leaf senescence, and for the first time, six senescencerelated endopeptidases （CEP1, 5, 6, 7, 8 and 9） were found in cucumber leaves.

关键词： Cucumis sativus cucumber endopeptidase leaf senescence.

Clinical effect of spleen aminopeptide on improving liver function damage and immune function in children with infant hepatitis syndrome

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1742-1748页

作者： Xiao-Qing Fang Tian Gan lie-Min wang Department of Pediatrics General Hospital of Central Theater Command of PLAWuhan 430061Hubei ProvinceChina Department of Pharmacy The First People’s Hospital of Jiangxia DistrictWuhan 430200Hubei ProvinceChina Department of Neonatal Central Hospital of EnshiEnshi 445000Hubei ProvinceChina

BACKGROUND Infant hepatitis syndrome(IHS)is a clinical syndrome in infants less than one year of age with generalized skin jaundice,abnormal liver function,and hepato-megaly due to various etiologies such as *** To investigate the effect of IHS patients,after treatment with arsphenamine-based peptides,on patients'liver function damage and immune *** Of 110 patients with IHS treated in our hospital from January 2019 to January 2021 were grouped according to the randomized residual grouping method,with 5 cases in each group shed due to transfer,***,50 cases remained in each *** control group was treated with reduced glutathione,and the treat-ment group was treated with sesquiterpene peptide based on the control *** and compare the differences in indicators after *** The comparison of serum total bilirubin,direct bilirubin,and serum alanine transferase after treatment was significantly different and lower in the treatment group than in the control group(P<0.05).The comparison of CD4+,CD3+,CD4+/CD8+after treatment was significantly different and higher in the treatment group than in the control group,and the comparison was statist-ically significant(P<0.05).The complication of the two groups showed that the rash,cough and sputum,elevated platelets,and gastrointestinal reactions in the treatment group were significantly lower than those in the control group,and the differences were statistically significant by test(P<0.05).CONCLUSION The comparative study of IHS treated with arsphenamine combined with reduced glutathione is more effective.

关键词： Infant hepatitis syndrome Splenamin Reduced glutathione Liver function Immune function Complication

Kinetic Phase Transition in A_2+2B_2→2B_2A Reaction System with Particle Diffusion

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Communications in Theoretical Physics 2008年第4期49卷 960-964页

作者： HUA Da-Yin WENG Xiao-Yan wang lie-Yan CHEN Ting Physics Department Ningbo University Ningbo 315211 China

A lattice gas model is presented for the A2 ＋2B2 → 2B2A reaction system with particle diffusion in two dimensions. In the model, B2 dissociates in the random dimer-filling mechanism and A2 dissociates in the end-on dimer filling mechanism. A reactive window appears and the system exhibits a continuous phase transition from a reactive state to a ＂B ＋ vacancy＂ covered state with infinitely many absorbing states. When the diffusion of particle B is considered, there are only two absorbing states. It is found that the critical behavior of the continuous phase transition changes from the directed percolation （DP） class to the pair contact process with diffusion （PCPD） class.

关键词： non-equilibrium phase transition reaction diffusion system

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Cellular & Molecular Immunology 2014年第3期11卷 232-244页

作者： Xia Liu Shengxia Yin Wenqiang Cao Wei Fan Lei Yu Li Yin lie wang Jianli wang Institute of Immunology Zhejiang University School of Medicine Hangzhou China

The interplay between the CD4-1ineage transcription factor ThPok and the CD8-iineage transcription factor, runt-related transcription factor 3 （Runx3）, in T-cell development has been extensively documented. However, little is known about the roles of these transcription factors in invariant natural killer T （iNKT） cell development. CDld-restricted iNKT cells are committed to the CD4＋CD8- and CD4-CD8- sublineages, which respond to antigen stimulation with rapid and potent release of T helper （Th） 1 and Th2 cytokines. However, previous reports have demonstrated a new population of CD8~ NKT cells in ThPok-deficient mice. In the current study, we sought to determine whether Runx3 was involved in the re-expression of CD8 and function of iNKT cells in the absence of ThPok. We used mice lacking Runx3, ThPok or both and verified that Runx3 was partially responsible for the appearance of CD8^＋ iNKT cells in ThPok knockout mice. Additionally, Runx3 participated in the immune response mediated by iNKT cells in a model of α-galactosylceramide-induced acute hepatitis. These results indicate that Runx3 is crucial for the phenotypic and functional changes observed in ThPok-deficient iNKT cells.

关键词： α-galactosylceramide iNKT cells liver Runx3 ThPok