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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： Xiaodong Yang Haochen Shen Xiaoming Xiao Zhichao li Qi Zhou wei Yang Bin Jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting

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铁路企业出资者所有权监管问题研究

铁道运输与经济 2004年第8期26卷 25-29页

作者：王芸李冬伟华东交通大学经济管理学院江西南昌330013

随着我国铁路企业改革的深入,一些非运输企业按照现代企业制度的要求进行公司制改组。对此铁路出资者应按照“两权”分离原则,行使出资者的所有权管理职能,并对其出资承担监管和保值增值的责任。通过分析铁路企业出资者所有权监管存在... 详细信息

随着我国铁路企业改革的深入,一些非运输企业按照现代企业制度的要求进行公司制改组。对此铁路出资者应按照“两权”分离原则,行使出资者的所有权管理职能,并对其出资承担监管和保值增值的责任。通过分析铁路企业出资者所有权监管存在的问题,提出相应的解决对策。

关键词：铁路企业出资者所有权监管管理职能中国改制

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汽车标准视角下必要专利问题应对机制研究

标准科学 2022年第2期 6-12页

作者：李云伟李维菁陆春中国汽车技术研究中心有限公司

本文通过分析标准必要专利内涵及其对汽车标准化的影响,研究国外标准化组织标准必要专利问题处置方法,结合我国国情,以汽车标准管理流程为主体,提出汽车标准必要专利问题应对机制,完善汽车标准管理制度,填补汽车标准必要专利领域研究空白。

关键词：汽车标准必要专利应对机制

基于体验视角的文化旅游深度开发策略研究——以浙江金华为例

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金华职业技术学院学报 2013年第5期13卷 39-43页

作者：王蕊李维云江苏师范大学江苏徐州221116 金华职业技术学院浙江金华321007

体验经济时代要求文化旅游产品的开发要遵循个性化、情境化、真实性、创新性、高度参与性的原则。而目前金华市文化旅游产品除了一些节事类旅游产品外,绝大多数文化旅游产品仍停留在观光游览阶段,难以满足体验时代游客的需求。在对金华... 详细信息

体验经济时代要求文化旅游产品的开发要遵循个性化、情境化、真实性、创新性、高度参与性的原则。而目前金华市文化旅游产品除了一些节事类旅游产品外,绝大多数文化旅游产品仍停留在观光游览阶段,难以满足体验时代游客的需求。在对金华市的文化旅游资源及其开发模式进行梳理的基础上,提出要进一步深层次挖掘文化旅游产品内涵,打造节事活动精品,创新文化旅游产品形式,将隐形文化旅游资源外显化并注重提高文化旅游产品科技含量等建议策略。

关键词：体验文化旅游金华

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跳频卫星通信同步技术研究

无线通信技术 2012年第1期21卷 33-36页

作者：员利卫王喆兰州交通大学电子与信息工程学院兰州730070

跳频同步是跳频通信技术的关键。考虑到抗干扰的需要,将跳频体制引入到卫星通信中。比较常规跳频同步实现方法的优缺点,根据设备低复杂度以及同步捕获时间短的要求,将同步头+TOD的同步方法引入到跳频卫星通信系统中,研究了同步序列格式... 详细信息

跳频同步是跳频通信技术的关键。考虑到抗干扰的需要,将跳频体制引入到卫星通信中。比较常规跳频同步实现方法的优缺点,根据设备低复杂度以及同步捕获时间短的要求,将同步头+TOD的同步方法引入到跳频卫星通信系统中,研究了同步序列格式,同步头的结构,同步频率的算法,设计了初始同步的方案。

关键词：跳频同步同步头 TOD

Precise gradient separation of nanoparticles using reduced graphene oxide-polyoxomolybdate membranes

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Science China Chemistry 2025年第01期 209-216页

作者： Yixin Yang Wanlei Zhao Ruoxuan Zheng Hongqiang li wei Chen Yu-Fei Song State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Quzhou Institute for Innovation in Resource Chemical Engineering

The purification and size sieving of nanoparticles （NPs） represents a significant scientific ***,the r GO-polyoxometalates (POMs=PMo12,Mo132and Mo368) membranes were fabricated successfully via a simple and scalable POMsassisted in-situ photoreduction *** the mass ratio of r GO to PMo12was 1:30,the resultant r GO-PMo12membranes with highly ordered and uniform nanochannels of 1.0 nm can be obtained,which showed an accurate carbon quantum dots（CQDs） separation with a cut-off size approximately 1.0 *** increase of the size of the interlayered POMs from PMo12（1.0 nm）,{Mo132}（2.9 nm） to{Mo368}（3.8 nm）,the resultant r GO-PMo12,r GO-Mo132and r GO-Mo368exhibited precise gradient separation of CQDs and Au nanoparticles by size exclusion *** results pave a promising way to construct new twodimensional （2D） membranes for highly efficient size-selective separation.

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A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi li Yang wei Kang Zhou Xin Huang Xing Zhou Jie Xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （lic *** three-sodium storage mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting li wei Zhang Jian Wu Hui Hong wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong liu Xiaolin li Xiaowei Zhou wei Chen Aidong Wen Minna liu Yi Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics

5-羟色胺转运体基因多态性与慢性阻塞性肺疾病相关性研究

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中国药理学通报 2017年第5期33卷 681-684页

作者：李雪芹李运景赵伟国缪炯燏王怀良中山市人民医院药学部广东中山528403 中山市人民医院呼吸内科广东中山528403 中国医科大学临床药理学教研室辽宁沈阳110001

目的探讨5-羟色胺转运体(SERT)基因多态性与慢性阻塞性肺疾病(COPD)的相关性。方法按入选、排除标准,选择COPD患者51例,对照组为同期健康体检者49例。用PCR方法检测SERT基因多态性;用Real-time RT-PCR方法检测SERT基因mRNA表达。对COPD... 详细信息

目的探讨5-羟色胺转运体(SERT)基因多态性与慢性阻塞性肺疾病(COPD)的相关性。方法按入选、排除标准,选择COPD患者51例,对照组为同期健康体检者49例。用PCR方法检测SERT基因多态性;用Real-time RT-PCR方法检测SERT基因mRNA表达。对COPD组患者进行肺功能检查,记录第1秒用力呼气量(FEV1)、用力肺活量(FVC)和FEV1/FVC%。结果无论COPD组还是健康对照组,均发现3种SERT基因型L/L(528/528)、L/S(528/484)和S/S(484/484),其中SS基因型为主要基因型;COPD组SERT基因表达明显高于对照组;COPD组伴有肺动脉高压(PAH)患者的L等位基因频率明显高于对照组;COPD组LS基因型患者COPD发病年龄小于SS基因型患者。结论 SERT基因多态性与COPD的遗传易感性相关,对促进COPD形成及诱发PAH有一定作用。

关键词： 5-羟色胺 5-羟色胺转运体基因多态性慢性阻塞性肺疾病肺动脉高压遗传易感性