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Zinc isotopic behavior of mafic rocks during continental deep subduction

Geoscience Frontiers 2021年第5期12卷 182-191页

作者： li-juan xu Sheng-Ao liu Shuguang li State Key Laboratory of Geological Processes and Mineral Resources School of Scientific ResearchChina University of GeosciencesBeijing 100083China

Zinc isotopes may act as a new tool of tracking recycling of crustal materials that causes compositional heterogeneity of the *** application relies on an investigation of Zn isotopic behaviors during slab *** this study,we report Zn isotopic compositions for a suite of metabasalts(greenschists,amphibolites,and coesitebearing eclogites)from the Dabie Orogen(China),which were formed via the subduction of mafic rocks into different depths and up to>200 *** out of eight greenschists are characterized by lighterδ^(66)ZnJMC-Lyon(0.10‰-0.16‰)than those of global basalts(0.28‰±0.05‰),which may be caused by crustal assimilation of the protoliths by sedimentary rocks due to their extremely high ^(87)Sr/^(86)Sr(up to 0.7130)and lowεNd values(down to−12.3).The remaining greenschists have relatively low ^(87)Sr/^(86)Sr and theirδ66Zn values(0.21‰-0.38‰)overlap the ranges of amphibolites(0.18‰-0.32‰)and coesite-bearing eclogites(0.18‰-0.36‰).There is no correlation betweenδ^(66)Zn and sensitive indicators of dehydration(Rb/TiO_(2),Ba/Yb,and H_(2)O+),suggesting that no detectable Zn isotope fractionation has occurred during the deep subduction of mafic rocks even into>200 km,which is attributed to the limited loss of Zn during prograde metamorphism and ***,Zn isotopic compositions of the deeply subducted mafic rocks are inherited from their *** that these metamorphosed rocks have higherδ66Zn than that of the mantle value by up to 0.2‰,the recycled/subducted mafic crust can incorporate isotopically heavy Zn into the *** subducted slabs may partially melt and generate a metasomatized mantle,resulting in changes of Zn isotopic composition of the hybridized mantle as have been observed in some mantle xenoliths and basaltic lavas.

关键词： Zn isotopes Metamorphosed rocks Dehydration Crustal deep subduction

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An Approach to Analyze Physical Memory Image File of Mac OS X

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Journal of Harbin Institute of Technology(New Series) 2014年第4期21卷 116-120页

作者： li-juan xu lian-Hai Wang Shandong Provincial Key Laboratory of Computer Network Shandong Computer Science Center( National Supercomputer Center in Jinan)

Memory analysis is one of the key techniques in computer live forensics. Especially,the analysis of a Mac OS X operating system's memory image file plays an important role in identifying the running status of an apple computer. However,how to analyze the image file without using extra"mach-kernel"file is one of the unsolved difficulties. In this paper,we firstly compare several approaches for physical memory acquisition and analyze the effects of each approach on physical memory. Then,we discuss the traditional methods for the physical memory file analysis of Mac OS X. A novel physical memory image file analysis approach without using extra"mach-kernel"file is proposed base on the discussion. We verify the performance of the new approach on Mac OS X 10. 8. 2. The experimental results show that the proposed approach is simpler and more practical than previous ones.

关键词： computer forensics live forensics Mac OS X operating system physical memory analysis

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Thermal Oxidation of Silicon Carbide Substrates

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Journal of Materials Science & Technology 2009年第1期25卷 115-118页

作者： Xiufang Chen liana Ning Yingmin Wang juan li Xiangang xu Xiaobo Hu Minhua Jiang State Key Laboratory of Crystal Materials Shandong University Jinan 250100 China

Thermal oxidation was used to remove the subsurface damage of silicon carbide （SIC） surfaces. The anisotropy of oxidation and the composition of oxide layers on Si and C faces were analyzed. Regular pits were observed on the surface after the removal of the oxide layers, which were detrimental to the growth of high quality epitaxial layers. The thickness and composition of the oxide layers were characterized by Rutherford backscattering spectrometry （RBS） and X-ray photoelectron spectroscopy （XPS）, respectively. Epitaxial growth was performed in a metal organic chemical vapor deposition （MOCVD） system. The substrate surface morphology after removing the oxide layer and gallium nitride （GaN） epilayer surface were observed by atomic force microscopy （AFM）. The results showed that the GaN epilayer grown on the oxidized substrates was superior to that on the unoxidized substrates.

关键词： SiC Thermal oxidation GaN epitaxy

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Clinical characteristics of acute non-varicose upper gastrointestinal bleeding and the effect of endoscopic hemostasis

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World Journal of Clinical Cases 2024年第9期12卷 1597-1605页

作者： Xiao-juan Wang Yu-Peng Shi li Wang Ya-Ni li li-juan xu Yue Zhang Shuang Han Department of Gastroenterology Honghui Hospital Affiliated to Medicine College of Xi’an Jiaotong UniversityXi'an 710054Shaanxi ProvinceChina

BACKGROUND Acute non-variceal upper gastrointestinal bleeding(ANVUGIB)constitutes a prevalent emergency within Gastroenterology,encompassing 80%-90%of all gastrointestinal hemorrhage *** condition is distinguished by its abrupt onset,swift progression,and notably elevated mortality *** To gather clinical data from patients with ANVUGIB at our hospital in order to elucidate the clinical characteristics specific to our institution and analyze the therapeutic effectiveness of endoscopic *** We retrospectively retrieved the records of 532 patients diagnosed with ANVUGIB by endoscopy at our hospital between March 2021 and March 2023,utilizing our medical record *** pertaining to general patient information,etiological factors,disease outcomes,and other relevant variables were meticulously collected and *** Among the 532 patients diagnosed with ANVUGIB,the male-to-female ratio was 2.91:1,with a higher prevalence among ***,43.6%of patients presented with black stool as their primary complaint,while 27.4%had hematemesis as their initial *** admission,17%of patients exhibited both hematemesis and black stool,while most ANVUGIB patients primarily complained of overt gastrointestinal *** routine blood examinations at admission revealed that 75.8%of patients had anemia,with 63.4%experiencing moderate to severe anemia,and 1.5%having extremely severe anemia(hemoglobin<30 g/L).With regard to etiology,53.2%of patients experienced bleeding without a definitive trigger,24.2%had a history of using gastric mucosa-irritating medications,24.2%developed bleeding after alcohol consumption,2.8%attributed it to improper diet,1.7%to emotional excitement,and 2.3%to fatigue preceding the bleeding ***-induced ANVUGIB was more prevalent in the elderly than middle-aged and young individuals,while bleeding due to alcohol consumption showed the opposite ***,diet-related bleeding was more common

关键词： Acute non-varicose upper gastrointestinal bleeding Clinical characteristics Cause of disease Endoscopic homeostatic therapy

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Hsa_circRNA_102610 upregulation in Crohn’s disease promotes transforming growth factor-β1-induced epithelial-mesenchymal transition via sponging of hsa-miR-130a-3p

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World Journal of Gastroenterology 2020年第22期26卷 3034-3055页

作者： juan Yin Yu-Lan Ye Tong Hu li-juan xu li-Ping Zhang Ru-Ning Ji Ping li Qian Chen Jian-Yun Zhu Zhi Pang Department of Digestive Disease and Nutrition Research Center the Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou 215008Jiangsu ProvinceChina Department of Gastroenterology the Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou 215008Jiangsu ProvinceChina Department of Biomedical Engineering the Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou 215008Jiangsu ProvinceChina

BACKGROUND The incidence of inflammatory bowel disease,a chronic intestinal inflammatory disorder that includes Crohn’s disease(CD)and ulcerative colitis,is *** RNAs are considered valuable diagnostic biomarkers for *** evidence supports the views that epithelial-mesenchymal transition(EMT)plays an important role in CD pathogenesis,and that hsa-miR-130a-3p can inhibit transforming growth factor-β1(TGF-β1)-induced *** previous study revealed that hsa_circRNA_102610 was upregulated in CD ***,we predicted an interaction between hsa_circRNA_102610 and ***,we hypothesized that hsa_circRNA_102610 may play roles in the proliferation and EMT of intestinal epithelial cells by sponging hsa-miR-130a-3p to participate in the pathogenesis of *** To explore the mechanism of hsa_circRNA_102610 in the pathogenesis of *** The relative expression levels of hsa_circRNA_102610 and hsa-miR-130a-3p in patients were detected by quantitative reverse transcription-polymerase chain *** proliferation of human intestinal epithelial cells(HIECs)and normal-derived colon mucosa cell line 460(NCM460)cells was detected by cell counting kit-8,5-ethynyl-2’-deoxyuridine staining and cell cycle assays following overexpression or downregulation of hsa_circRNA_*** proliferation assays were performed as described above in a rescue experiment with hsa-miR-130a-3p *** interaction of hsa_circRNA_102610 and hsa-miR-130a-3p was verified by fluorescence in situ hybridization and dual luciferase reporter *** relative expression levels of CyclinD1,mothers against decapentaplegic homolog 4(SMAD4),E-cadherin,N-cadherin and Vimentin were detected by western blotting following hsa_circRNA_102610 overexpression,TGF-β1-induced EMT or hsa-miR-130a-3p mimic transfection(in rescue experiments).RESULTS Upregulation of hsa_circRNA_102610 was determined to be positively correlated with elevated fecal calprotectin levels in CD(r=0.3

关键词： Hsa_circRNA_102610 Hsa-miR-130a-3p Epithelial-mesenchymal transition Crohn’s disease Mothers against decapentaplegic homolog 4 Transforming growth factor-β1

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Cloning and Characterization of a Novel cDNA Encoding Late Embryogenesis-Abundant Protein 5 like (LEA-5) Gene from Cara Cara Navel Orange Fruit (Citrus sinensis Osbeck)

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Agricultural Sciences in China 2006年第4期5卷 272-276页

作者： TAO Neng-guo YE Jun-li xu juan DENG Xiu-xin National Key Laboratory of Crop Genetic Improvement National Center of Crop Molecular Breeding Huazhong Agricultural University Wuhan 430070 P.R.China

LEA5 gene was postulated related with both stress and hormone responses. In an attempt to find genes exclusively expressed during fruit ripening of Cara Cara navel orange, a novel cDNA clone encoding late embryogenesis-abundant protein 5 like gene （CitLEA5-1） was obtained. It was 582 bp in length, containing 97 deduced amino acids. Compared with the stress-induced LEA5 from leaves of Citrus sinensis, CitLEA5-1 had a shorter 3′ untranslated region （UTR）. Semi-quantitative RT-PCR analysis revealed that CitLEA5-1 was transcriptional regulated during fruit ripening of Cara Cara navel orange.

关键词： Citrus cloning characterization late embryogenesis-abundant protein

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Microstructure characterization and tensile properties of a Ni-containing TiAl-based alloy with heat treatment

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Rare Metals 2016年第1期35卷 26-34页

作者： Jian-Chao Han Shu-Long Xiao Jing Tian Yu-Yong Chen li-juan xu Xiao-Peng Wang Yi Jia Shou-Zhen Cao School of Materials Science and Engineering Harbin Institute of Technology National Key Laboratory of Science and Technology on Precision Heat Processing of Metals Harbin Institute of Technology State Key Laboratory of Advanced Welding and Joining Harbin Institute of Technology

The effects of Ni addition on solidification micro structure and tensile properties of Ti-48Al-2Cr-2Nb alloy were investigated using differential scanning calorimetry（DSC）,X-ray diffraction（XRD）,scanning electron microscopy（SEM） equipped with energy-dispersive spectroscope（EDS） and transmission electron microscopy（TEM）.Results show that with 3 at%Ni addition,the as-cast micro structure is mainly composed of fine lamellar colonies（~50 μm）,γ grains and Ni-ridied τ_3 *** heat treatment at 1380℃,the Ni-containing alloy is characterized by fine fully lamellar micro structure（~90 μm）.The heat-treated Ni-containing specimen exhibits superior room temperature tensile properties than other *** tensile properties are discussed in light of the microstructure evolution and role of Ni-riched τ_3 phase.

关键词： TiAl-based intermetallics Solidificationmicrostructure Heat treatment Phase transformation Tensile properties

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Microstructure evolution of Ti–46Al–6Nb–(Si,B) alloys during heat treatment with W addition

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Rare Metals 2016年第1期35卷 85-92页

作者： Shou-Zhen Cao Shu-Long Xiao Yu-Yong Chen Jing Tian li-juan xu Xiao-Peng Wang Jian-Chao Han Yi Jia National Key Laboratory of Science and Technology on Precision Heat Processing of Metals Technology Harbin 150001China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China

The cast ingots of Ti-46Al-6Nb-0.25Si-0.2B and Ti-46Al-6Nb-0.5W-0.25Si-0.2B（at%） were made by induction skull melting（ISM） technique.A series of heat treatments（HTs） were conducted to research the microstructure evolution of both *** and tensile property were examined by scanning electron microscope（SEM）,X-ray diffraction（XRD）,transmission electron microscope（TEM）,and tensile testing *** results show that microsegregation（liquid segregation and solid segregation） is exacerbated by the addition of0.5 at%W;the addition of Nb,W in TiAl alloy makes the phase transition difficultly take place;then,the microstructures and tensile properties of both alloys are improved after certain HT processes;finally,the thicknesses of the γ/α_2 lamellae after a certain HT process are significantly affected by the number of residual γ phases before the furnace-cooling moment.

关键词： TiAl alloy Heat treatment W addition Microstructure evolution Microsegregation

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Adipose-derived stromal cells resemble bone marrow stromal cells in hepatocyte differentiation potential in vitro and in vivo

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World Journal of Gastroenterology 2017年第38期23卷 6973-6982页

作者： li-juan xu Shu-fang Wang De-Qing Wang lian-jun Ma Zheng Chen Qian-Qian Chen Jun Wang li Yan Department of Gastroenterology Institute of Geriatrics Chinese PLA General Hospital Department of Blood Transfusion Chinese PLA General Hospital Department of Endoscopics China-Japan Union Hospital of Jilin University Department of Gastroenterology Institute of Surgery Research Daping Hospital Third Military Medical University

AIM To investigate whether mesenchymal stem cells(MSCs) from adipose-derived stromal cells(ADSCs) and bone marrow stromal cells(BMSCs) have similar hepatic differentiation *** Mouse ADSCs and BMSCs were isolated and cultured. Their morphological and phenotypic characteristics, as well as their multiple differentiation capacity were compared. A new culture system was established to induce ADSCs and BMSCs into functional hepatocytes. Reverse transcription polymerase chain reaction, Western blot, and immunofluorescence analyses were performed to identify the induced hepatocytelike cells. CM-Dil-labeled ADSCs and BMSCs were then transplanted into a mouse model of CCl4-induced acute liver failure. fluorescence microscopy was used to track the transplanted MSCs. liver function was tested by an automatic biochemistry analyzer, and liver tissue histology was observed by hematoxylin and eosin(HE) *** ADSCs and BMSCs shared a similar morphology and multiple differentiation capacity, as well as a similar phenotype(with expression of CD29 and CD90 and no expression of CD11 b or CD45). Morphologically, ADSCs and BMSCs became round and epithelioid following hepatic induction. These two cell types differentiated into hepatocyte-like cells with similar expression of albumin, cytokeratin 18, cytokeratin 19, alpha fetoprotein, and cytochrome P450. fluorescence microscopy revealed that both ADSCs and BMSCs were observed in the mouse liver at different time points. Compared to the control group, both the function of the injured livers and HE staining showed significant improvement in the ADSC-and BMSC-transplanted mice. There was no significant difference between the two MSC *** ADSCs share a similar hepatic differentiation capacity and therapeutic effect with BMSCs in an acute liver failure model. ADSCs may represent an ideal seed cell type for cell transplantation or a bio-artificial liver support system.

关键词： Adipose-derived stromal cells Bone marrow stromal cells Cell differentiation Hepatocyte differentiation

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Effect of tumor size on dermoscopic features of pigmented basal cell carcinoma

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Chinese Medical Journal 2021年第15期134卷 1866-1868页

作者： li-juan xu ling-ling Zheng Wei Zhu Department of Dermatology Xuan Wu HospitalCapital Medical UniversityBeijing 100053China Department of Dermatology Beijing Luhe HospitalCapital Medical UniversityBeijing 101100China

Basal cell carcinoma(BCC)is the most common malignant tumor of the skin and the incidence increases yearly *** BCC is an indolent kind of tumor,it can grow into a large lesion and lost its classic *** addition,giant BCC has attracted the attention of researchers in recent years.111 Thus,BCC with a large tumor size also catches our *** is a useful adjuvant tool for the diagnosis and management of BCCs.[2].There are few literatures on BCC tumor size and BCC dermoscopic *** observed and analyzed 98 cases of BCCs and found that dermoscopic features of BCCs>1 cm in diameter were different from that of smaller BCCs.

关键词： diagnosis size features

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