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Communications in Mathematical Research 2012年第2期28卷 97-107页

作者： li wen-jin PANG YAN-NI School of Management Jilin University Changchun 130025 School of Mathematics Jilin University Changchun 130012

This paper develops an extended newsboy model and presents a formula- tion for this model. This new model has solved the budget contained multi-product newsboy problem with the reactive production. This model can be used to describe the status of entrepreneurial network construction. We use the Lagrange multiplier procedure to deal with our problem, but it is too complicated to get the exact solu-tion. So we introduce the homotopy method to deal with it. We give the flow chart to describe how to get the solution via the homotopy method. We also illustrate our model in both the classical procedure and the homotopy method. Comparing the two methods, we can see that the homotopy method is more exact and efficient.

关键词： newsboy problem entrepreneurial network construction multi-product budget constrained reactive production homotopy method

Robust global motion estimation

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Optoelectronics Letters 2007年第4期3卷 303-307页

作者： DING Jia-rui li Zhong-jian AN jin-wen College of Automation Nonhwestern Polytechnical UniversityXi’an710072China

A global motion estimation method based on robust statistics is presented in this paper. By using tracked feature points instead of whole image pixels to estimate parameters the process speeds up. To further speed up the process and avoid numerical instability, an alterative description of the problem is given, and three types of solution to the problem are compared. By using a two step process, the robustness of the estimator is also improved. Automatic initial value selection is an advantage of this method. The proposed approach is illustrated by a set of examples, which shows good results with high speed.

关键词：运动估计鲁棒性鲁棒统计学轨迹特征点

A novel ophthalmic viscosurgical devicefree phakic intraocular lens implantation makes myopic surgery safer

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Eye and Vision 2020年第1期7卷 171-179页

作者： An-Peng Pan li-jin wen Xu Shao Kai-jing Zhou Qin-Mei Wang Jia Qu A-Yong Yu The Eye Hospital of wenzhou Medical University 270 Xueyuan West Road

Purpose:To assess the efficacy and safety of a novel ophthalmic viscosurgical device-free(OVD-free)method for posterior chamber phakic intraocular lens(PIOL)implantation in myopic ***:In this retrospective cohort study,the medical records of myopic eyes that underwent PIOL(Implantable Collamer Lens,ICL)implantation for myopia correction at the Eye Hospital of wenzhou Medical University between May 2015 and March 2017 were reviewed.A total of 49 eyes with complete data that met follow up requirements(2 h,1 day,1 week,3 months postoperatively)were *** on the surgical techniques used,the eyes were divided into the OVD-free method group and the standard method *** clinical data,including intraocular pressure(IOP),corrected distance visual acuity(CDVA)and spherical equivalent(SE),at each follow-up were collected for *** cell loss and complications were also ***:Twenty-one eyes received the standard method,and 28 eyes received the OVD-free method.A rise in IOP>22 mmHg at 2 h was noted in 14 eyes(66.7%)in the standard group and none(0%)in the OVD-free group(pline was significantly higher at 2 h in the standard group(10.5±5.2 mmHg vs.2.2±3.3 mmHg,difference:8.3,95%CI 5.8 to 10.8;plial cell loss was 4.6%at 3 months(2522±281 vs.2407±226 cells/mm^(2),difference:-115,95%CI−295 to 65;p=0.187).No complications were reported in both groups except for the early IOP elevation in the standard

关键词： Phakic intraocular lens implantation Ophthalmic viscosurgical device-free Intraocular pressure Complications

Underlying mechanism of ASIC1a involved in acidosis-induced cytotoxicity in rat C6 glioma cells

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Acta Pharmacologica Sinica 2007年第11期28卷 1731-1736页

作者： Xie-chuan wenG,Jian-quan ZHENG~2,jin li,wen-bin XIAOBeijing Institute of Pharmacology and Toxicology,Beijing 100850,China g Institute of Pharmacology and Toxicology Beijing 100850 China. wengxc2002@***.

Aim:To investigate the underlying mechanism of acid-sensing ion channel (ASIC)la involved in the acidosis-induced cytotoxicity of rat C6 glioma ***:The stable ASIC 1 a-silenced C6 cells built with the RNA interference technologywere confirmed by RT-PCR and Western blot *** calcium([Ca2+]i) in both the wild-type rat C6 glioma cells and the ASIC 1a-silenced C6 cellswere analyzed before and after acid application/exposure with the calcium ***:The rapid extracellular pH drop induced the increase of[Ca2+]iin the wild-type C6 cells,but not in the ASIC1a-silenced C6 *** prolonged acid exposure,[Ca2+]iwas lower in the ASIC 1 a-silenced C6 cellsthan that in the control ***:The resultant toxicity of [Ca2+]imightcontribute to the acidosis-induced cytotoxicity.

关键词： acid-sensing ion channel calcium calcium imaging Fluo-3

Mechanism underlying blockade of voltage-gated calcium channels by agmatine in cultured rat hippocampal neurons

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Acta Pharmacologica Sinica 2004年第3期 27-31页

作者： Jian-quan ZHENG2,Xie-chuan wenG,Xiao-dan GAI,jin li,wen-bin XIAO Beijing Institute of Pharmacology & Toxicology,Beijing 100850,China

AIM: To investigate whether agmatine could selectively block a given type of the voltage-gated calcium channels (VGCC) and whether related receptors are involved in the blocking effect of agmatine on VGCC. METHODS: The whole-cell patch recording technique was performed to record VGCC currents in the cultured neonatal rat hippo- campal neurons. RESULTS: Verapamil (100 μmol/L), a selective blocker of L-type calcium channel, significantly inhibited VGCC current by 80 %± 7 %. Agmatine (100 μmol/L) could further depress the remained currents by 25 %±6 %. The α2-adrenoceptor antagonist yohimbine (10 μmol/L) and the I2 imidazoline receptor antagonist idazoxon (10 and 40 μmol/L) had no significant effect on VGCC currents when used respectively. When the mixture of yohimbine and agmatine was applied, VGCC currents were still depressed remarkably. However, the blocking effect of agmatine was decreased by 29 %± 8 % in the presence of idazoxon (10 μmol/L). The effect of idazoxon did not increase at a higher concentration (40 μmol/L). CONCLUSION: Agmatine could block the L- and other types of VGCC currents in the cultured rat hippocampal neurons. Blocking effect of agmatine on VGCC was partially related to I2 imidazoline receptor and had no relationship with α2-adrenoceptors.

关键词： agmatine patch-clamp techniques calcium channels imidazoline receptors α adrenergic recep- tors

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复视45例的病因分析

国际眼科杂志 2010年第5期10卷 1017-1018页

作者：金丽文中国辽宁省阜新市第二人民医院眼科 123000

目的:探讨复视的病因及临床特点。方法:对复视患者45例进行视力、眼位、眼球运动及复视检查,并进行血液生化和影像学检查,分析复视的发病原因。结果:复视患者45例中单眼复视3例(7%),双眼复视42例(93%)。其中伴眼肌运动障碍的双眼复视40... 详细信息

目的:探讨复视的病因及临床特点。方法:对复视患者45例进行视力、眼位、眼球运动及复视检查,并进行血液生化和影像学检查,分析复视的发病原因。结果:复视患者45例中单眼复视3例(7%),双眼复视42例(93%)。其中伴眼肌运动障碍的双眼复视40例,病因包括:神经源性29例(64%)(其中脑血栓12例,脑出血7例,颅内肿瘤4例,流感3例,颅内血管瘤1例,颅脑外伤1例,鼻咽癌1例),肌源性3例(7%),神经肌肉接头处病变1例(2%),机械性5例(11%),原因不明2例(4%)。结论:本组患者复视的主要病因为脑血管病,脑肿瘤和眶壁骨折。

关键词：复视病因

An efficient quantum proactive incremental learning algorithm

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 49-57页

作者： lingxiao li jing li Yanqi Song Sujuan Qin Qiaoyan wen Fei Gao State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications School of Cyberspace Security Beijing University of Posts and Telecommunications

In scenarios where a large amount of data needs to be learned, incremental learning can make full use of old knowledge, significantly reduce the computational cost of the overall learning process, and maintain high performance. In this paper, taking the MaxCut problem as our example, we introduce the idea of incremental learning into quantum computing, and propose a Quantum Proactive Incremental Learning algorithm(QPIL). Instead of a one-off training of quantum circuit, QPIL contains a multi-phase training on gradually-increased subgraphs of all vertices, proactively reducing large-scale problems to smaller ones to solve in steps, providing an efficient solution for MaxCut. Specifically, some vertices and corresponding edges are randomly selected for training to obtain optimized parameters of the quantum circuit at first. Then, in each incremental phase, the remaining vertices and corresponding edges are gradually added and the parameters obtained from the previous phase are reused in the parameter initialization of the current phase. We perform experiments on 120 different small-scale graphs, and it shows that QPIL performs superior to prevalent quantum and classical baselines in terms of approximation ratio(AR), time cost, anti-forgetting, and solving stability. In particular, QPIL's AR surpasses 20% of mainstream quantum baselines, and the time cost is less than 1/5 of them. The idea of QPIL is expected to inspire efficient and high-quality solutions in large-scale Max Cut and other combinatorial optimization problems.

关键词： variational quantum algorithm incremental learning multi-phase training MaxCut quantum computing

High precision measurement of formaldehyde in air with differential optical absorption spectroscopy

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Optoelectronics Letters 2007年第6期3卷 451-454页

作者： PENG Fu-min, XIE Pin-hua, liN Yi-hui, li Yu-jin, li Su-wen, QIN Min, and liU wen-qing Key Laboratory of Environmental Optics and Technology, Chinese Academy of Sciences Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031, China Key Laboratory of Environmental Optics and Technology Chinese Academy of Sciences Hefei China

The formaldehyde (HCHO) measurement is described by differential optical absorption spectroscopy (DOAS) technique and the data processing method is discussed in detail, including the selection of retrieval wavelength band, the removing of interfering structures, the steps of data processing and the spectrum dealing with nonlinear method. The HCHO concentra- tion retrieved in different wavelength bands were compared, including relative error, repeatability and detection limit. As a result, the band from 314 to 332 nm was most suitable for the retrieval of HCHO. With these methods, high measurement precision of 1.9% was obtained and the detection limit of HCHO is less than 1.5 ppb. In addition, high linear relativity 0.9999 is achieved by measuring five different concentrations of HCHO with this system.

关键词：光检测技术精密度甲醛微分光学

纳米金标记抗体增强SPR检测大肠杆菌O157∶H7

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高等学校化学学报 2013年第6期34卷 1333-1338页

作者：刘霞李蓉卓李蕾李文进周春娇湖南农业大学食品科技学院食品科学与生物技术湖南省重点实验室湖南农业大学理学院长沙410128

将金纳米粒子(AuNPs)标记的大肠杆菌O157∶H7(*** O157∶H7)的多克隆抗体(PAb)作为二抗,采用氨基偶联法将PAb固定在传感器表面作为一抗,通过三明治方法用双通道表面等离子体子共振(SPR)传感器对*** O157∶H7进行检测,并与SPR直接法检测... 详细信息

将金纳米粒子(AuNPs)标记的大肠杆菌O157∶H7(*** O157∶H7)的多克隆抗体(PAb)作为二抗,采用氨基偶联法将PAb固定在传感器表面作为一抗,通过三明治方法用双通道表面等离子体子共振(SPR)传感器对*** O157∶H7进行检测,并与SPR直接法检测进行了比较.结果表明,直接法的检出限为103cfu/mL,线性范围为103～109cfu/mL;AuNPs增强三明治法的检出限为10 cfu/mL,线性范围为10～1010cfu/mL,灵敏度比直接法提高了100倍,且具有更宽的检测范围.本方法不仅检测时间短,而且具有良好的选择性和重现性.

关键词：金纳米粒子大肠杆菌O157∶H7 表面等离子体子共振标记检测

都市边缘农村地区环境问题成因及其整治对策——以上海市华新镇为例

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浙江农业学报 2014年第1期26卷 247-253页

作者：李金文上海市环境科学研究院环境健康与农村生态研究所上海200233

都市边缘农村地区因其独特的地理位置、社会经济及人口结构而呈现出不同于一般农村地区的环境问题,一般农村以农业生产为主,农业面源污染所占负荷较大,而都市边缘农村承接了都市中心区的产业转移,工业污染负荷远超农业面源污染;一般农... 详细信息

都市边缘农村地区因其独特的地理位置、社会经济及人口结构而呈现出不同于一般农村地区的环境问题,一般农村以农业生产为主,农业面源污染所占负荷较大,而都市边缘农村承接了都市中心区的产业转移,工业污染负荷远超农业面源污染;一般农村以本地人口为主,而都市边缘农村承接大量外来人口,生活污水、生活垃圾产生量较大,环境管理难以展开。本文以典型的都市边缘农村地区——上海市青浦区华新镇为例,从产业发展与外来人口导入的角度,剖析该地区环境问题产生的原因,并针对都市边缘农村地区生活污水、垃圾突出的问题,提出连片处置对策,为类似地区环境整治提供参考。

关键词：都市边缘农村城镇化农村环境问题新二元结构