检索结果-南通市图书馆

The regulatory role of m^(6)A modification in the maintenance and differentiation of embryonic stem cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & diseases 2024年第5期11卷 126-139页

作者： Jin zhang lingling Tong Yuchen liu Xiang li Jiayi Wang Ruoxin lin Ziyu Zhou Yunbing Chen Yanxi Chen Yirong liu di Chen Center for Reproductive Medicine of the Second Affiliated Hospital Center for Regeneration and Cell Therapy of Zhejiang University-University of Edinburgh Institute(ZJU-UoE Institute)Zhejiang University School of MedicineZhejiang UniversityHangzhouZhejiang 310003China Zhejiang University-University of Edinburgh Institute(ZJU-UoE Institute) Zhejiang University School of MedicineZhejiang UniversityHangzhouZhejiang 310003China College of Materials and Chemical Engineering Minjiang UniversityFuzhouFujian 350108China National Key Laboratory of Biobased Transportation Fuel Technology HainingZhejiang 314400China

As the most prevalent and reversible internal epigenetic modification in eukaryotic mRNAs,N6-methyladenosine(m^(6)A)post-transcriptionally regulates the processing and metabolism of mRNAs involved in diverse biological processes.m^(6)A modification is regulated by m^(6)A writers,erasers,and *** evidence suggests that m^(6)A modification plays essential roles in modulating the cell-fate transition of embryonic stem *** investigation of embryonic stem cell maintenance and differentiation is critical for understanding early embryonic development,which is also the premise for the application of embryonic stem cells in regenerative *** review highlights the current knowledge of m^(6)A modification and its essential regulatory contribution to the cell fate transition of mouse and human embryonic stem cells.

关键词： Cell-fate transition Embryonic stem cell Epigenetic modification m^(6)A modification Post-transcriptional regulation

Engineering tantalum nitride for efficient photoelectrochemical water splitting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第7期67卷 2171-2180页

作者： Beibei zhang Zeyu Fan Yanbo li Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

Photoelectrochemical(PEC)water splitting is a promising energy conversion strategy for directly converting solar energy into green hydrogen *** an efficient PEC device,finding an efficient photoanode material with a suitable band gap and favorable band-edge positions is *** nitride(Ta_(3)N_(5))meets these fundamental requirements,and its theoretical maximum solar-to-hydrogen(STH)conversion efficiency can reach 15.9%.Consequently,it has been widely applied as a photoanode material for the PEC oxygen evolution reaction(OER).However,severe bulk and interface charge recombination,along with sluggish water oxygen kinetics,seriously limits its STH conversion efficiency for PEC water ***,this feature article briefly reviews recent advances by our research group in improving the STH conversion efficiency of the Ta_(3)N_(5)photoanode using various strategies,including defect engineering,construction of a gradient band structure,interface engineering,and surface modification of self-healing OER *** to now,the obtained half-cell STH efficiency has exceeded 4%,providing a solid foundation for the development of tandem PEC devices for unbiased solar-driven overall water splitting toward practical application.

关键词： Photoelectrochemical water splitting tantalum nitride defect engineering interface engineering oxygen evolution cocatalyst

High strength mullite-bond SiC porous ceramics fabricated by digital light processing

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2024年第1期13卷 53-62页

作者： Jian Sun Jingde zhang Xu zhang Zihe li Jianzhang li Sijie Wei Weibin zhang Weili Wang Guifang Han Key Laboratory for liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) School of Materials Science and EngineeringShandong UniversityJinan 250061China Key Laboratory of Special Functional Aggregated Materials Ministry of EducationShandong UniversityJinan 250100China Materials and Structures Research Centre Department of Mechanical EngineeringUniversity of BathBath BA27AYUK National Engineering Research Centre of Ceramic Matrix Composite Manufacture Technology Xi’an Golden Mountain Ceramic Composites Co.Ltd.Xi’an 710118China School of Physics and Materials Science Changji UniversityChangji 831100China

Fabricating SiC ceramics via the digital light processing(DLP)technology is of great challenge due to strong light absorption and high refractive index of deep-colored SiC powders,which highly differ from those of resin,and thus significantly affect the curing performance of the photosensitive SiC *** this paper,a thin silicon oxide(SiO_(2))layer was in-situ formed on the surface of SiC powders by pre-oxidation *** method was proven to effectively improve the curing ability of SiC *** SiC photosensitive slurry was fabricated with solid content of 55 vol%and viscosity of 7.77 Pa·s(shear rate of 30 s^(−1)).The curing thickness was 50μm with exposure time of only 5 ***,a well-designed sintering additive was added to completely convert low-strength SiO_(2) into mullite reinforcement during *** mullite-bond SiC ceramics were successfully *** flexural strength of SiC ceramics sintered at 1550℃in air reached 97.6 MPa with porosity of 39.2 vol%,as high as those prepared by spark plasma sintering(SPS)techniques.

关键词： digital light processing(DLP) SiC ceramics pre-oxidation mullite-bond SiC mechanical properties

light-based 3D printing of stimulus-responsive hydrogels forminiature devices:recent progress and perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2024年第5期7卷 721-746页

作者： Chen Xin Neng Xia li zhang Department of Mechanical and Automation Engineering The Chinese University of Hong KongHong Kong 999077China Multi-Scale Medical Robotics Center Hong Kong Science ParkShatin NTHong Kong 999077China Chow Yuk Ho Technology Center for Innovative Medicine The Chinese University of Hong KongHong Kong 999077China Department of Surgery The Chinese University of Hong KongHong Kong 999077China CUHK T Stone Robotics Institute The Chinese University of Hong KongHong Kong 999077China

Miniature devices comprising stimulus-responsive hydrogels with high environmental adaptability are now considered competitive candidates in the fields of biomedicine,precise sensors,and tunable *** and advanced fabricationmethods are critical formaximizing the application capabilities ofminiature ***-based three-dimensional(3D)printing technology offers the advantages of a wide range of applicable materials,high processing accuracy,and strong 3D fabrication capability,which is suitable for the development of miniature devices with various *** paper summarizes and highlights the recent advances in light-based 3D-printed miniaturized devices,with a focus on the latest breakthroughs in lightbased fabrication technologies,smart stimulus-responsive hydrogels,and tunable miniature devices for the fields of miniature cargo manipulation,targeted drug and cell delivery,active scaffolds,environmental sensing,and optical ***,the challenges in the transition of tunable miniaturized devices from the laboratory to practical engineering applications are *** opportunities that will promote the development of tunable microdevices are elaborated,contributing to their improved understanding of these miniature devices and further realizing their practical applications in various fields.

关键词： 3D printing Stimulus-responsive hydrogels Miniature devices Shape-morphing

Joint fuzzy background and adaptive foreground model for moving target detection

在线全文

学校读者我要写书评

暂无评论

Frontiers of Computer Science 2024年第2期18卷 93-106页

作者： Dawei zhang Peng WANG Yongfeng DONG linhao li Xin li School of Artificial Intelligence Hebei University of TechnologyTianjin 300401China Lane Department of Computer Science and Electrical Engineering West Virginia UniversityMorgantownWV 26506-6109USA

Moving target detection is one of the most basic tasks in computer *** conventional wisdom,the problem is solved by iterative optimization under either Matrix Decomposition(MD)or Matrix Factorization(MF)*** utilizes foreground information to facilitate background *** uses noise-based weights to fine-tune the *** both noise and foreground information contribute to the recovery of the *** jointly exploit their advantages,inspired by two framework complementary characteristics,we propose to simultaneously exploit the advantages of these two optimizing approaches in a unified framework called Joint Matrix Decomposition and Factorization(JMDF).To improve background extraction,a fuzzy factorization is *** fuzzy membership of the background/foreground association is calculated during the factorization process to distinguish their contributions of both to background *** describe the spatio-temporal continuity of foreground more accurately,we propose to incorporate the first order temporal difference into the group sparsity constraint *** temporal constraint is adjusted *** foreground and the background are jointly estimated through an effective alternate optimization process,and the noise can be modeled with the specific probability *** experimental results of vast real videos illustrate the effectiveness of our *** with the current state-of-the-art technology,our method can usually form the clearer background and extract the more accurate ***-noise experiments show the noise robustness of our method.

关键词： matrixdecomposition matrix factorization generalized sparsity noise modeling

Evidence of ancient rock-ice avalanches along the China-Bhutan Chomolhari Range,and their implications for demise of the summit

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第9期21卷 2876-2890页

作者： HU Kaiheng zhang Qiyuan li Pu zhang Xiaopeng liU Shuang li Hao Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610299China University of Chinese Academy of Sciences Beijing 100149China

Large-scale rock-ice avalanches resulting from the interaction of tectonics and climate are characterized with high mobility,huge volumes of sediment,and rapid denudation,being a major agent of landscape evolution in high altitude mountainous ***,the extreme glaciated slope failures often transform into extraordinarily large and mobile debris flows,resulting in disastrous consequences such as sedimentation and *** to a dearth of on-site observation data and experimental data collection,our comprehension of the geomorphic and kinematic characteristics of rock-ice avalanches remains *** we report a cluster of ancient rock-ice avalanches spreading along the Chomolhari range of the China-Bhutan *** integrating remote sensing image interpretation with detailed field investigations,we demonstrate the geomorphic and sedimentary characteristics of four events among the *** estimated volumes of the four are 23.73 Mm³,39.69 Mm³,38.43 Mm³,and 38.25 Mm³,*** presence of pre-existing moraines or alluvial fans constrained their movement,resulting in deposition features such as marginal digitated lobes at higher elevations and large depressed areas in the *** the Savage-Hutter theory,we calculate the basal friction angle and travel angle of these ancient rock-ice avalanches that are both less than 10°,affirming the similarity of these avalanches in the study area to those occurring in other *** study significantly contributes to understanding the geomorphic and kinematic characteristics of rock-ice avalanches in high-altitude mountainous regions,providing valuable insights into their response to the disproportionate growth of Himalayan peaks.

关键词： Rock-ice avalanche Himalayas Southern Yadong-Gulu rift Vertical slip-rate Landscape evolution

Semi-supervised remote sensing image scene classification with prototype-based consistency

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第2期37卷 459-470页

作者： Yang li zhang li Zi WANG Kun WANG Qifeng YU College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China

Deep learning significantly improves the accuracy of remote sensing image scene classification,benefiting from the large-scale ***,annotating the remote sensing images is time-consuming and even tough for *** neural networks trained using a few labeled samples usually generalize less to new unseen *** this paper,we propose a semi-supervised approach for remote sensing image scene classification based on the prototype-based consistency,by exploring massive unlabeled *** this end,we,first,propose a feature enhancement module to extract discriminative *** is achieved by focusing the model on the foreground ***,the prototype-based classifier is introduced to the framework,which is used to acquire consistent feature *** conduct a series of experiments on NWPU-RESISC45 and Aerial Image Dataset(AID).Our method improves the State-Of-The-Art(SOTA)method on NWPU-RESISC45 from 92.03%to 93.08%and on AID from 94.25%to 95.24%in terms of accuracy.

关键词： Semi-supervised learning Remote sensing Scene classification Prototype network Deep learning

Effect of Interface Form on Creep Failure and life of dissimilar Metal Welds Involving Nickel-Based Weld Metal and Ferritic Base Metal

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2024年第1期37卷 265-285页

作者： Xiaogang li Junfeng Nie Xin Wang Kejian li Haiquan zhang Institute of Nuclear and New Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of EducationTsinghua UniversityBeijing 100084China Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China

For dissimilar metal welds(DMWs)involving nickel-based weld metal(WM)and ferritic heat resistant steel base metal(BM)in power plants,there must be an interface between WM and BM,and this interface suffers mechanical and microstructure mismatches and is often the rupture location of premature *** this study,a new form of WM/BM interface form,namely double Y-type interface was designed for the *** behaviors and life of DMWs containing double Y-type interface and conventional I-type interface were compared by finite element analysis and creep tests,and creep failure mechanisms were investigated by stress-strain analysis and microstructure *** applying double Y-type interface instead of conventional I-type interface,failure location of DMW could be shifted from the WM/ferritic heat-affected zone(HAZ)interface into the ferritic HAZ or even the ferritic BM,and the failure mode change improved the creep life of *** interface premature failure of I-type interface DMW was related to the coupling effect of microstructure degradation,stress and strain concentrations,and oxide notch on the WM/HAZ *** creep failure of double Y-type interface DMW was the result of Type IV fracture due to the creep voids and micro-cracks on fine-grain boundaries in HAZ,which was a result of the matrix softening of HAZ and lack of precipitate pinning at fine-grain *** double Y-type interface form separated the stress and strain concentrations in DMW from the WM/HAZ interface,preventing the trigger effect of oxide notch on interface failure and inhibiting the interfacial microstructure *** is a novel scheme to prolong creep life and enhance reliability of DMW,by means of optimizing the interface form,decoupling the damage factors from WM/HAZ interface,and then changing the failure mechanism and shifting the failure location.

关键词： dissimilar metal weld Nickel-based weld metal Ferritic heat resistant steel Interface Creep strain Microstructure Failure mechanism Creep life

Lyapunov Conditions for Finite-Time Input-to-State Stability of Impulsive Switched Systems

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 1057-1059页

作者： Taixiang zhang Jinde Cao Xiaodi li the School of Mathematics Southeast UniversityNanjing 210096China the School of Mathematics and Statistics Shandong Normal UniversityJinan 250014Chi

Dear Editor,This letter studies finite-time input-to-state stability(FTISS)for impulsive switched systems.A set of Lyapunov-based conditions are established for guaranteeing FTISS *** constituent modes governing continuous dynamics are FTISS and discrete dynamics involving impulses are destabilizing,the FTISS can be retained if impulsive-switching signals satisfy an average dwell-time(ADT)condition.

关键词： property impulsive satisfy