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Chinese Journal of Chemistry 2021年第1期39卷 75-80页

作者： Huangong li Yangyang Zhao Pengwei Sun li Gao Yuxin li lixia Xiong Na Yang Sha Zhou Zhengming li State Key Laboratory of Elemento-Orgonic Chemistry Research Institute of Elemento-Orgonic ChemistryCollege of ChemistryNonkai UniversityTianjin 300071China

To search for potent insecticides targeting at ryanodine receptors(RyRs),a series of novel anthranilic diamides analogs containing 4-chlorine N-pyridylpyrazole were designed and *** insecticidal activities were evaluated and the preliminary struc ture-activity relationships(SARs)were *** insecticidal results showed that some of the compounds(8a-8h,8m,8n)exhibited good larvicidal activities against oriental armyworm at 2.5 mg·L^(-1),and compound 8m possessed 60%insecticidal activityat 0.5 mg·L^(-1).For diamondback moth,8m exhibited better activity than Chlorantraniliprole at a hundred fold preference.

关键词： Synthesis design Anthranilic diamides Insecticidal activity RyRs Structure-activity relationships

A perspective on off-policy evaluation in reinforcement learning

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Frontiers of Computer Science 2019年第5期13卷 911-912页

作者： lihong li Google Brain Kirkland WA 98033 USA

The goal of reinforcement learning (RL) is to build an autonomous agent that takes a sequence of actions to maximize a utility function by interacting with an external, unknown environment. It is a very general learning paradigm that can model a wide range of problems, such as games, robotics, autonomous driving, humancomputer interactions, recommendation, healthcare, and many others. In recent years, powered by advances in deep learning and computing power, RL has seen great successes, with AlphaGo/AlphaZero as a prominent example. Such impressive outcomes have sparked fast growing interests in using RL to solve real-life problems.

关键词： evaluation reinforcement learning

Interface-Optical-Phonon Modes in Quasi-one-dimensional Wurtzite Rectangular Quantum Wires

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Communications in Theoretical Physics 2006年第6X期46卷 1109-1112页

作者： ZHANG li Department of Mechanism and Electron Panyu Polytechnic Panyu 511483~ China

By employing the dielectric continuum model and Loudon＇s uniaxial crystal model, the interface optical （IO） phonon modes in a freestanding quasi-one-dimensional （Q1D） wurtzite rectangular quantum wire are derived and analyzed. Numerical calculation on a freestanding wurtzite GaN quantum wire is performed. The resulte reveal that the dispersion frequencies of IO modes sensitively depend on the geometric structures of the Q1D wurtzite rectangular quantum wires, the free wave-number kz in z-direction and the dielectric constant of the nonpolar matrix. The degenerating behavior of the IO modes in Q1D wurtzite rectangular quantum wire has been clearly observed in the case of small wave-number kz and Iarge ratio of length to width of the rectangular crossing profile. The limited frequency behaviors of IO modes have been analyzed deeply, and detailed comparisons with those in wurtzite planar quantum wells and cylindrical quantum wires are also done. The present theories can be looked on as a generalization of that in isotropic rectangular quantum wires, and it can naturally reduce to the case of Q1D isotropic quantum wires once the anisotropy of the wurtzite material is ignored.

关键词： interface phonon modes polarization eigenvectors rectangular quantum wire

Performance verification and comparison of TianLong automatic hypersensitive hepatitis B virus DNA quantification system with Roche CAP/CTM system

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World Journal of Gastroenterology 2017年第37期23卷 6845-6853页

作者： Ming li lin Chen li-Ming liu Yong-li li Bo-An li Bo li Yuan-li Mao li-Fang Xia Tong Wang Ya-Nan liu Zheng li Tong-Sheng Guo School of Mechanical Engineering Xi'an Jiaotong University Xi'an Tian Long Science and Technology Co. Ltd. Center of Clinical Laboratory Medicine 302 Military Hospital of China Department of Laboratory Medicine Beijing Xiaotangshan Hospital

AIM To investigate and compare the analytical and clinical performance of Tian Long automatic hypersensitive hepatitis B virus(HBV) DNA quantification system and Roche CAP/CTM *** Two hundred blood samples for HBV DNA testing, HBV-DNA negative samples and high-titer HBV-DNA mixture samples were collected and prepared. National standard materials for serum HBV and a worldwide HBV DNA panel were employed for performance verification. The analytical performance, such as limit of detection, limit of quantification, accuracy, precision, reproducibility, linearity, genotype coverage and cross-contamination, was determined using the Tian Long automatic hypersensitive HBV DNA quantification system(TL system). Correlation and Bland-Altman plot analyses were carried out to compare the clinical performance of the TL system assay and the CAP/CTM system. RESULTS The detection limit of the TL system was 10 IU/m L, and its limit of quantification was 30 IU/m L. The differences between the expected and tested concentrations of the national standards were less than ± 0.4 Log10 IU/m L, which showed high accuracy of the system. Results of the precision, reproducibility and linearity tests showed that the multiple test coefficient of variation(CV) of the same sample was less than 5% for 102-106 IU/m L; and for 30-108 IU/m L, the linear correlation coefficient r2 = 0.99. The TL system detected HBV DNA(A-H) genotypes and there was no cross-contamination during the "checkerboard" test. When compared with the CAP/CTM assay, the two assays showed 100% consistency in both negative and positive sample results(15 negative samples and 185 positive samples). No statistical differences between the two assays in the HBV DNA quantification values were observed(P > 0.05). Correlation analysis indicated a significant correlation between the two assays, r2 = 0.9774. The Bland-Altman plot analysis showed that 98.9% of the positive data were within the 95% acceptable range, and the maximum di

关键词： Analytical performance Hepatitis B virus DNA quantification Clinical performance Hepatitis B virus Real-time quantification PCR

Implementation of Disaster Reduction Measures and Enhancement of Integrated Risk Governance in China

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International Journal of Disaster Risk Science 2013年第2期4卷 101-104页

作者： li Jiang Ministry of Civil Affairs of China Academy of Disaster Reduction and Emergency Management Beijing Normal University

Summary of the Remarks at the High-Level Dialogue,Official Statement,and Plenary Session of the Fourth Session of the Global Platform on Disaster Risk Reduction,21–23 May 2013,Geneva,*** past several years have witnessed the toughest period of natural disasters in Chinese history,in terms of frequency and concurrency,as well as variability in damage and *** Chinese government takes action quickly and engages in disaster emergency response and disaster relief work with huge human resource and material inputs.

关键词： disaster tough Reduction

A mini review on oxidative dehydrogenation of propane over boron nitride catalysts

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Petroleum Science 2023年第4期20卷 2488-2498页

作者： Zhu Fu De-Zheng li li-Dai Zhou Yu-Ming li Jia-Wen Guo Yu-Qiao li Hui-Min liu Qi-Jian Zhang School of Chemical and Environmental Engineering Liaoning University of TechnologyJinzhouLiaoning121001China State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China

Oxidative dehydrogenation of propane is an attractive route for the synthesis of propylene due to its favorable thermodynamic and kinetic characteristics, however, it is challenging to realize high selectivity towards propylene. Recently, it has been discovered that boron nitride (BN) is a promising catalyst that affords superior selectivity towards propylene in oxidative dehydrogenation of propane. Summarizing the progress and unravelling the reaction mechanism of BN in oxidative dehydrogenation of propane are of great significance for the rational design of efficient catalysts in the future. Herein, in this review, the underlying reaction mechanisms of oxidative dehydrogenation of propane over BN are extracted;the developed BN catalysts are classified into pristine BN, functionalized BN, supported BN and others, and the applications of each category of BN catalysts in oxidative dehydrogenation of propane are summarized;the challenges and opportunities on oxidative dehydrogenation of propane over BN are pointed out, aiming to inspire more studies and advance this research field.

关键词： Oxidative dehydrogenation of propane Boron nitride Propylene Reaction mechanism

Behind the Artemisinin, efforts and persistence from numerous scientists

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Protein & Cell 2011年第11期2卷 862-863页

作者： Ming li Beijing Institutes of life Science Chinese Academy of SciencesBeijing 100101China

Professor Youyou Tu(China Academy of Chinese Medical Sciences,Beijing)was awarded the 2011 Lasker~DeBakey Clinical Medical Research Award for her contribution toward the discovery of Artemisinin,also known as Qinghaos... 详细信息

关键词： Medical Clinical 青蒿素

Stable soliton propagation in a coupled (2+1) dimensional Ginzburg-Landau system

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Chinese Physics B 2020年第7期29卷 265-268页

作者： li-li Wang Wen-Jun liu State Key Laboratory of Information Photonics and Optical Communications and School of ScienceBeijing University of Posts and TelecommunicationsBeijing 100876China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China

A coupled(2+1)-dimensional variable coefficient Ginzburg-Landau equation is *** virtue of the modified Hirota bilinear method,the bright one-soliton solution of the equation is *** phenomena of soliton propagation are analyzed by setting different dispersion *** influences of the corresponding parameters on the solitons are also *** results can enrich the soliton theory,and may be helpful in the manufacture of optical devices.

关键词： soliton modified Hirota bilinear method Ginzburg-Landau equation bright soliton solution

Three-stage niobium mineralization at Bayan Obo, China

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National Science Review 2024年第4期11卷 102-110页

作者： Yan Yu Yang li Yu liu Xiao-Xiao ling li-Guang Wu li Yang Lan Yang Bo Yang Yong-Gang Zhao Xian-Hua li State Key Laboratory of lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences College of Earth and Planetary Science University of Chinese Academy of Sciences Ministry of Education Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking University Mining Research Institute Baotou Iron and Steel(Group) Co.LTD State Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization

The Chinese Bayan Obo deposit is a world-class rare earth element(REE) deposit with considerable niobium(Nb) and iron(Fe) resources. A complete genetic understanding on all metals is fundamental for establishing genetic models at Bayan Obo. With extensive research being focused on REE enrichment, the timing and controls of Nb enrichment remain unresolved at Bayan Obo, which is mainly due to the challenges in dating, i.e. multistage thermal events, fine-grained minerals with complex textures and the rare occurrence of uranium-enriched minerals with mature dating methods. Based on robust geological and petrographic frameworks, here we conducted ion probe uranium-lead(U-Pb) dating of ferrocolumbite to unravel the timing, hence the genesis of Nb mineralization. Three types of hydrothermal ferrocolumbites—key Nb-bearing minerals—are identified based on their textures and mineral assemblages. They yield U-Pb ages of 1312 ± 47 Ma(n = 99), 438 ± 7 Ma(n = 93), and 268 ± 5 Ma(n = 19), respectively. In line with deposit geology, we tentatively link the first, second and third stage Nb mineralization to Mesoproterozoic carbonatite magmatism, ubiquitous early Paleozoic hydrothermal activity, and Permian granitic magmatism, respectively. While quantifying the contribution of metal endowment from each stage requires further investigation, our new dates highlight that multi-stage mineralization is critical for Nb enrichment at Bayan Obo, which may also have implications for the enrichment mechanism of Nb in REE deposits in general.

关键词： niobium mineralization U-Pb dating ferrocolumbite Bayan Obo

Blood nitric oxide data reveals a new adaptive strategy of Tibetans to hypobaric hypoxia

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National Science Review 2018年第4期5卷 530-531页

作者： li Jin School of life Sciences Fudan University NSR

The study of‘Blunted nitric oxide regulation in Tibetans under high altitude hypoxia’provides important physiological data of native Tibetans,which has been interpreted as a previously unknown mechanism for the adaptation of Tibetans to highaltitude hypoxia[1].Tibetans are among the world’s high-altitude natives(the other example is Andeans)who have developed genetic adap-

关键词： Blood nitric oxide data reveals a new adaptive strategy of Tibetans to hypobaric hypoxia