Synthesis and Insecticidal Evaluation of Novel Anthranilic Diamides Derivatives Containing 4-Chlorine Substituted N-Pyridylpyrazole

作     者：Huangong Li Yangyang Zhao Pengwei Sun Li Gao Yuxin Li Lixia Xiong Na Yang Sha Zhou Zhengming Li Huangong Li;Yangyang Zhao;Pengwei Sun;Li Gao;Yuxin Li;Lixia Xiong;Na Yang;Sha Zhou;Zhengming Li

作者机构：State Key Laboratory of Elemento-Orgonic ChemistryResearch Institute of Elemento-Orgonic ChemistryCollege of ChemistryNonkai UniversityTianjin 300071China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2021年第39卷第1期

页      面：75-80页

核心收录：

学科分类：090403[农学-农药学(可授农学、理学学位）] 09[农学] 0904[农学-植物保护] 

基　　金：The project was supported by the National Key Research Program-The Innovation of Eco-Modulator of Insect Ryanodine Re-ceptor(Nos.2018YFD0200100,2017YFD0200505) the National Natural Science Foundation of China(Nos.31972287,21602118) 

主　　题：Synthesis design Anthranilic diamides Insecticidal activity RyRs Structure-activity relationships 

摘      要：To search for potent insecticides targeting at ryanodine receptors(RyRs),a series of novel anthranilic diamides analogs containing 4-chlorine N-pyridylpyrazole were designed and *** insecticidal activities were evaluated and the preliminary struc ture-activity relationships(SARs)were *** insecticidal results showed that some of the compounds(8a-8h,8m,8n)exhibited good larvicidal activities against oriental armyworm at 2.5 mg·L^(-1),and compound 8m possessed 60%insecticidal activityat 0.5 mg·L^(-1).For diamondback moth,8m exhibited better activity than Chlorantraniliprole at a hundred fold preference.