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Chinese Medical Journal 2006年第10期119卷 871-874页

作者： FAN Jun MA Wei-hang YANG Mei-fang XUE Han GAO Hai-nü li lan-juan Key Laboratory of Ministry Infectious Disease Institute ofInfectious Diseases First Affiliated Hospital Zhejiang UniversitySchool of Medicine Hangzhou 310003 China

Cytomegalovirus （CMV） infection is a major and often deadly complication of haematopoietic stem cell （HSC） transplantation. Successful preemptive CMV therapy in transplant patients depends on the availability of sensitive, specific, and timely diagnostic tests for CMV infections. The pp65 antigenemia assay has been used for this purpose with considerable success but has disadvantages of being time-consuming and labor-intensive .

关键词： haematopoietic stem cell transplantation cytomegalovirus real-time systems polymerase chain reaction

Fully distributed dynamic event-triggered formation-containment tracking for multiagent systems with multiple types of disturbances

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Science China(Information Sciences) 2024年第1期67卷 168-186页

作者： Weihua li Huaguang ZHANG juan ZHANG Rui WANG College of Information Science and Engineering Northeastern University State Key Laboratory of Synthetical Automation for Process Industries Northeastern University

This paper is dedicated to addressing the time-varying output formation-containment tracking(TVOFCT) problem for heterogeneous linear multiagent systems(MASs) with multiple types of disturbances under directed communication *** agents are divided into tracking leaders,formation leaders,and *** the output space,the formation leaders are required to form an expected geometric formation while tracking the tracking leader,and the followers are required to enter the convex hull spanned by formation ***,a disturbance observer is designed to observe the disturbance with deterministic ***,by combining adaptive technology with event-triggered technology,an independent fully distributed dynamic event-triggered(FDDET) compensator is designed to estimate the state of the tracking *** main advantages of this compensator lie in the following three aspects:(1) the adaptive weight does not increase unboundedly;(2) the interval time between events is expanded;(3) the design does not rely on any global *** to the design of this compensator,an independent FDDET convex hull observer is further designed to observe the convex hull spanned by formation ***,based on the designed disturbance observer,compensator,and convex hull observer,the adaptive disturbance rejection control input which can make the MASs achieve TVOFCT is ***,a numerical simulation is provided to clearly verify the validity of the theoretical results.

关键词： formation-containment tracking disturbance rejection multiagent systems fully distributed control dynamic event-triggered control

Multifunctional carbon materials from rugose rose for energy storage and water purification

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Frontiers of Chemical Science and Engineering 2024年第9期18卷 1-13页

作者： Peng-Hui li Hui Zhou Wen-juan Wu Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources Nanjing Forestry UniversityNanjing 210037China College of light Industry and Food Engineering Nanjing Forestry UniversityNanjing 210037China College of Chemical Engineering East China University of Science and TechnologyShanghai 200237China State Key Laboratory of Chemical Engineering Shanghai 200237China

With the advancement of social process,the resource problem is becoming more prominent,biomass materials come into being,and it is becoming more and more important to explore and prepare efficient and multifunctional biomass materials to alleviate the problems of energy storage and water *** this paper,nitrogen-doped hierarchical porous carbon materials(NRRC)were produced by one-step carbonization of withered rose as raw material and melamine as nitrogen source with KOH-activated *** resulting nitrogen-doped porous carbon material had the most abundant pores and the best microspherical graded pore structure,with a specific surface area of up to 1393 m2·g^(-1),a pore volume of 0.68 cm3·g^(-1),and a nitrogen-doped content of 5.52%.Electrochemical tests showed that the maximum specific capacitance of NRRC in the three-electrode system was 346.4 F·g^(-1)(0.5 A·g^(-1)),which was combined with favorable capacitance retention performance and cycling *** NRRC//NRRC symmetric supercapacitors were further assembled,and the maximum energy density of a single device was 23.88 Wh·kg^(-1),which still maintains excellent capacitance retention and cyclic charging/discharging *** example,the capacitance retention rate was always close to 96.27%with almost negligible capacitance loss after 10000 consecutive charge/discharge cycles(current density:10 A·g^(-1)).Regardless of the three-electrode or two-electrode system,the super capacitive performance of NRRC porous carbon materials was comparable to the electrochemical performance of many reported biomass porous carbon materials,which showed better energy storage advantages and practical application *** addition,NRRC porous carbon materials had excellent water purification *** dye adsorption test confirmed that NRRC had a high adsorption capacity(491.47 mg·g^(-1))for methylene *** undoubtedly also showed a potential and promising avenue for high value-added utilization

关键词： rose carbon adsorption electrode material electrochemical performance

Discovery of CCDC188 gene as a novel genetic target for human acephalic spermatozoa syndrome

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Protein & Cell 2024年第9期15卷 704-709页

作者： Jing Wang Hui-juan Jin Yi Lu Zi-Han Wang Teng-Yan li lan Xia Hong-Jun li Bin-Bin Wang Su-Ren Chen Department of Medical Genetics and Developmental Biology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Key Laboratory of Cell Proliferation and Regulation Biology Ministry of EducationDepartment of BiologyCollege of Life SciencesBeijing Normal UniversityBeijing 100875China Graduate School Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100005China Department of Urology Peking Union Medical College HospitalBeijing 100005China Center for Genetics National Research Institute of Family PlanningBeijing 100081China NHC Key Laboratory of Reproductive Health Engineering Technology Research(NRIFP) Beijing 100081China

Dear Editor,Male infertility is a widespread health problem and affects approximately 6%–8%of the male population(Jiao et al.,2021).Acephalic spermatozoa syndrome(ASS),a rare but severe type of teratozoospermia,is ch... 详细信息

关键词： al. infertility finally

Design and synthesis of polyoxovanadate-based framework for efficient dye degradation

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Tungsten 2024年第2期6卷 447-453页

作者： Qing lan Su-juan Jin Zheng Wang Xu-Yang li Yan Xiong Zhuo-Cheng Wang Shan-Shan liu Zhi-Ming Zhang Qiang Zhao Engineering Technology Research Center of Henan Province for Solar Catalysis School of Chemical and Pharmaceutical EngineeringNanyang Normal UniversityNanyang 473061China Institute of New Energy Materials&Low Carbon Technology Tianjin University of TechnologyTianjin 300384China

A new polyoxovanadate-based framework material[Cu(en)_(2)]_(4)V_(18)O_(42)(H_(2)O)·6H_(2)O(1)was designed and synthesized by hydrothermal reaction of NaVO_(3),Cu(NO_(3))_(2)·6H_(2)O and 1,2-diaminoethane(en)via carefully adjusting the pH value of the reaction *** structure of the title compound has been determined by single-crystal X-ray diff raction analysis,thermogravimetric analysis,infrared spectra and elemental *** structural analysis demonstrate the three-dimensional(3D)framework structure of compound 1,which was composed of the[V_(18)O_(42)(H_(2)O)]_(8)−({V_(18)O_(42)(H_(2)O)})anions linked by the Cu^(2+)*** 1 represents the fi rst 3D framework based on{V_(18)O_(42)(H_(2)O)}polyoxoanions and copper ***-driven degradation of residual organic pollutants in industrial wastewater is still a major problem for human *** experiments reveal that compound 1 possesses of excellent photocatalytic activity for the degradation of methylene blue and rhodamine B.

关键词： Polyoxovanadate Framework Polyoxovanadate-based framework Photocatalytic Organic pollutants

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加强肝衰竭发病机制和人工肝治疗的研究

中华肝脏病杂志 2009年第5期17卷 321-323页

作者：李兰娟浙江大学医学院附属第一医院传染病诊治国家重点实验室杭州310003

重型病毒性肝炎（肝衰竭）严重危害我国人民的健康和生命，由于肝脏组织发生大块或亚大块坏死，乙型重型肝炎患者病情危笃，进展迅速，预后极差，病死率高达70％，是导致乙型肝炎患者死亡的主要原因。重型肝炎发病机制不明，缺乏敏感、... 详细信息

重型病毒性肝炎（肝衰竭）严重危害我国人民的健康和生命，由于肝脏组织发生大块或亚大块坏死，乙型重型肝炎患者病情危笃，进展迅速，预后极差，病死率高达70％，是导致乙型肝炎患者死亡的主要原因。重型肝炎发病机制不明，缺乏敏感、可靠的临床评估体系和特异、有效的治疗药物，是难以早期诊断、早期治疗和难以治愈的根本原因。

关键词：肝功能衰竭肝,人工肝细胞代谢组学

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肠道微生态改变对肝脏疾病的影响

中华肝脏病杂志 2013年第1期21卷 2-4页

作者：李兰娟浙江大学医学院附属第一医院传染病诊治国家重点实验室杭州310003

一、肠道微生态组成与改变在人体，肠道菌群是一个复杂的微生态系统，它们在机体出生时便开始形成，随后几天中逐步完善。

关键词：肝硬化肝性脑病肠道菌群益生菌

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努力提高我国病毒性肝炎的实验室诊断水平

中华检验医学杂志 2007年第8期30卷 845-849页

作者：李兰娟浙江大学医学院附属第一医院感染病中心杭州310003

提高实验室诊断水平对于病毒性肝炎的有效防治具有十分重要的作用。通过优化常规病毒性肝炎实验室诊断技术,使检测灵敏度、稳定性等方面达到国际水准。运用分子生物学、蛋白组学、代谢组学等平台,研发新型、快速、联合、多样化的病毒性... 详细信息

提高实验室诊断水平对于病毒性肝炎的有效防治具有十分重要的作用。通过优化常规病毒性肝炎实验室诊断技术,使检测灵敏度、稳定性等方面达到国际水准。运用分子生物学、蛋白组学、代谢组学等平台,研发新型、快速、联合、多样化的病毒性肝炎实验诊断技术。同时,按照循证医学要求,提高实验室数据的利用效率,切实改进我国病毒性肝炎的实验室诊断水平。

关键词：肝炎病毒实验室诊断

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肝衰竭临床治疗中的难点和热点

中华肝脏病杂志 2012年第6期20卷 405-407页

作者：李兰娟浙江大学医学院附属第一医院传染病诊治国家重点实验室杭州310003

肝衰竭是临床比较常见的严重肝病症候群，是临床治疗中的难点和热点。肝衰竭常由病毒、细菌感染以及药物、酒精中毒等各种不同病因引起，在我国尤以乙型肝炎病毒（HBV）导致的重型肝炎肝衰竭最为常见。由于肝脏组织发生大块或亚大块坏死，

关键词：肝功能衰竭治疗核苷(酸)类药物肝人工肝移植

Added Benefit of the Early-Morning-Orbit Satellite Fengyun-3E on the Global Microwave Sounding of the Three-Orbit Constellation

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Advances in Atmospheric Sciences 2024年第1期41卷 39-52页

作者： juan li Zhengkun QIN Guiqing liU Jing HUANG CMA Earth System Modeling and Prediction Centre Beijing 100081China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Joint Center for Data Assimilation Research and Applications School of Atmospheric SciencesNanjing University of Information Science&TechnologyNanjing 210044China

The three-orbit constellation can comprehensively increase the spatial coverage of polar-orbiting satellites,but the polar-orbiting satellites currently in operation are only mid-morning-orbit and afternoon-orbit ***-3E(FY-3E)was launched successfully on 5 July 2021 in *** an early-morning-orbit satellite,FY-3E can help form a complete three-orbit observation system together with the mid-morning and afternoon satellites in the current mainstream operational *** this study,we investigate the added benefit of FY-3E microwave sounding observations to the midmorning-orbit Meteorological Operational satellite-B(Met Op-B)and afternoon-orbit Fengyun-3D(FY-3D)microwave observations in the Chinese Meteorological Administration global forecast system(CMA-GFS).The results show that the additional FY-3E microwave temperature sounder-3(MWTS-3)and microwave humidity sounder-2(MWHS-2)data can increase the global coverage of microwave temperature and humidity sounding data by 14.8% and 10.6%,*** enables the CMA-GFS to achieve nearly 100% global coverage of microwave-sounding observations at each analysis ***,after effective quality control and bias correction,the global biases and standard deviations of the differences between observations and model simulations are also *** on the Advanced Microwave Sounding Unit A and the Microwave Humidity Sounder onboard Met Op-B,and the MWTS-2 and MWHS-2 onboard FY-3D,adding the microwave sounding data of FY-3E can further reduce the errors of analysis results and improve the global prediction skills of CMA-GFS,especially for the southern-hemisphere forecasts within 96 hours,all of which are significant at the 95% confidence level.

关键词： data assimilation microwave temperature sounder MWTS-3