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Reconstruction of Smoke Plume Concentration Peaks Based on Modified MAX-DOAS Tomography

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Chinese Journal of Chemical Physics 2015年第6期28卷 -页

作者： min-hong Wei min-ming Tong Su-wen li School of Physics and Electronic Information Huaibei Normal University Huaibei 235000 ChinaSchool of Information and Electrical Engineering China University of Mining and Technology Xuzhou 221116 China School of Information and Electrical Engineering China University of Mining and Technology Xuzhou 221116 China School of Physics and Electronic Information Huaibei Normal University Huaibei 235000 China

Optical tomographysystem based on modified simultaneous iterative reconstruction technique is designed to real-time monitor spatial distribution and diffusion process of smoke plume in a power plant. Concentration profiles, rather than just a point value, of smoke plume concentrations are the goal of this method, and the tomography algorithm is analyzed. According to incomplete projection data in the process of reconstruction and exiting noise interference, the modified simultaneous iterative reconstruction technique (SIRT) is adopted to extract the information of the trace gas concentration by a fan beam scanning and is compared to the conventional SIRT. Three evaluation indexes show that the reconstruction effect is the best by choosing proper relaxation factor, which reduces the index d to 0.044 from 0.435 and reduces the index r to 0.044 from 0.376 for 5500 iterations. Hence, the modified algorithm performs better in estimating the shape of the plume, this method is used to process the measured spectra in field campaign, the reconstruction results and the measured data are basically consistent, which is further confirmed by the experimental results.

关键词： Reconstruction DOAS tomography Retrieval Modified simultaneous iterative reconstruction technique

On a class of quantum Turing machine halting deterministically

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Science China(Physics,Mechanics & Astronomy) 2013年第5期56卷 941-946页

作者： liANG min YANG li State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of Sciences

We consider a subclass of quantum Turing machines (QTM), named stationary rotational quantum Turing machine (SR-QTM), which halts deterministically and has deterministic tape head position. A quantum state transition diagram (QSTD) is proposed to describe SR-QTM. With QSTD, we construct a SR-QTM which is universal for all near-trivial transformations. This indicates there exists a QTM which is universal for the above subclass. Finally we show that SR-QTM is computational equivalent with ordinary QTM in the bounded error setting. It can be seen that SR-QTMs have deterministic tape head position and halt deterministically, and thus the halting scheme problem will not exist for this class of QTMs.

关键词： quantum Turing machine quantum circuit halting scheme quantum computational complexity

Factorization of simple modules for certain restricted two-parameter quantum groups

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Frontiers of Mathematics in China 2013年第1期8卷 169-190页

作者： min li Xiuling WANG School of Mathematical Sciences Nankai University Tianjin 300071 China

We study the representations of the restricted two-parameter quantum groups of types B and G. For these restricted two-parameter quantum groups, we give some explicit conditions which guarantee that a simple module can be factored as the tensor product of a one-dimensional module with a module that is naturally a module for the quotient by central group-like elements. That is, given θ a primitive eth root of unity, the factorization of simple uθy,θz（g）-modules is possible, if and only if （2（y - z）,e） = 1 for 9 = SO2n＋l; （3（y- z）,g） = 1 for 9 = G2.

关键词： Hopf algebra Drinfel'd double restricted two-parameter quantumgroup

Protein interaction networks:centrality,modularity,dynamics,and applications

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Frontiers of Computer Science 2021年第6期15卷 1-17页

作者： Xiangmao MENG Wenkai li Xiaoqing PENG Yaohang li min li School of Computer Science and Engineering Central South UniversityChangsha 410083China School of life Science Central South UniversityChangsha 410083China Department of Computer Science Old Dominion UniversityNorfolk 23529-016USA

In the post-genomic era,proteomics has achieved significant theoretical and practical advances with the development of high-throughput *** the rapid accumulation of protein-protein interactions(PPIs)provides a foundation for constructing protein interaction networks(PINs),which can furnish a new perspective for understanding cellular organizations,processes,and functions at network *** this paper,we present a comprehensive survey on three main characteristics of PINs:centrality,modularity,and dynamics.1)Different centrality measures,which are used to calculate the importance of proteins,are summarized based on the structural characteristics of PINs or on the basis of its integrated biological information;2)Different modularity definitions and various clustering algorithms for predicting protein complexes or identifying functional modules are introduced;3)The dynamics of proteins,PPIs and sub-networks are discussed,***,the main applications of PINs in the complex diseases are reviewed,and the challenges and future research directions are also discussed.

关键词： protein interaction networks network centrality modularity dynamics complex diseases

Distribution of cube-free numbers with form [n^c]

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Frontiers of Mathematics in China 2017年第6期12卷 1515-1525页

作者： min ZHANG Jinjiang li Department of Mathematics China University of Mining and Technology Beijing 100083China

We prove that there are infinite cube-free numbers of the form [n^c] for any fixed real number c E （1, 11/6）.

关键词： Cube-free number exponential sum asymptotic formula

Universal quantum circuit of near-trivial transformations

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Science China(Physics,Mechanics & Astronomy) 2011年第10期54卷 1819-1827页

作者： liANG min YANG li State Key Laboratory of Information Security Graduate University of Chinese Academy of Sciences Beijing 100049 China

Any unitary transformation can be decomposed into a product of a group of near-trivial transformations. We investigate in detail theconstruction of universal quantum circuit of near trivial transformations. We first construct two universal quantum circuits whichcan implement any single-qubit rotation Ry(θ) and Rz(θ) within any given precision, and then we construct universal quantum circuitimplementing any single-qubit transformation within any given precision. Finally, a universal quantum circuit implementing anyn-qubit near-trivial transformation is constructed using the universal quantum circuits of Ry(θ) and Rz(θ). In the universal quantumcircuit presented, each quantum transformation is encoded to a bit string which is used as ancillary inputs. The output of the circuitconsists of the related bit string and the result of near-trivial transformation. Our result may be useful for the design of universalquantum computer in the future.

关键词： quantum computation quantum circuit universal quantum circuit near-trivial transformation

Topoisomerase I in Human Disease Pathogenesis and Treatments

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Genomics, Proteomics & Bioinformatics 2016年第3期14卷 166-171页

作者： min li Yilun liu Department of Cancer Genetics and Epigenetics Beckman Research Institute

Mammalian topoisomerase 1（TOP1） is an essential enzyme for normal ***1 relaxes supercoiled DNA to remove helical constraints that can otherwise hinder DNA replication and transcription and thus block cell ***,this exact activity can covalently trap TOP1 on the DNA that could lead to cell death or mutagenesis,a precursor for *** is therefore important for cells to find a proper balance between the utilization of the TOP1 catalytic activity to maintain DNA topology and the risk of accumulating the toxic DNA damages due to TOP1 trapping that prevents normal cell *** an apparent contradiction to the negative attribute of the TOP1 activity to genome stability,the detrimental effect of the TOP1-induced DNA lesions on cell survival has made this enzyme a prime target for cancer therapies to kill fast-growing cancer *** addition,cumulative evidence supports a direct role of TOP1 in promoting transcriptional progression independent of its topoisomerase *** involvement of TOP1 in transcriptional regulation has recently become a focus in developing potential new treatments for a subtype of autism spectrum ***,the impact of TOP1 on human health is *** this review,we will summarize our current understandings on how TOP1 contributes to human diseases and how its activity is targeted for disease treatments.

关键词： Topoisomerase 1 Cancer Autism Scleroderma DNA replication Transcription

Histone variants: the artists of eukaryotic chromatin

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Science China(life Sciences) 2015年第3期58卷 232-239页

作者： li min FANG YuDa National Key Laboratory of Plant Molecular Genetics Shanghai Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences

The eukaryotic genome is packaged into a complex nucleoprotein structure named chromatin, balancing the compactness of genome and the accessibility of regulatory proteins and RNA polymerases to DNA. The mechanisms of the regulation of chromatin dynamics include the post-translational modification of histones, alteration of nucleosome positions by chromatin remodelers, replacement of canonical histones by histone variants with the aid of histone chaperones, and dynamic organization of the three-dimensional genome in the small nucleus. Histone variants are different from canonical histones by substitution of several amino acid residues or changes in amino acid sequence. Histone variants perform specialized functions such as altering nucleosome stability, dynamics, structure, as well as playing critical roles in a range of biological processes like transcriptional regulation, DNA repair and recombination, development and immune responses. Here we discuss how histone variants, their modification and specific loading to chromatin are involved in transcriptional regulation, DNA repair and plant development.

关键词： histone variants histone modification gene regulation DNA repair stress responsiveness

Natural killer cells in hepatocellular carcinoma： current status and perspectives for future immunotherapeutic approaches

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Frontiers of Medicine 2017年第4期11卷 509-521页

作者： min Yu Zonghai li State Key Laboratory of Oncogenes and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiao Tong University School ofMedicine Shanghai 200032 China

Hepatocellular carcinoma （HCC） is currently the fifth most common malignancy and the third leading cause of cancer-related mortalities worldwide. In the last few years, treatments for HCC have significantly improved from a mere surgical resection to a series of minimally invasive therapies and targeted drugs. However, recurrence frequently occurs even upon curative therapeutics, and drug therapies generally produce disappointing results, with the overall prognosis dismal. This challenging clinical scenario warrants new effective and life-prolonging strategies for patients with HCC. Compelling evidence suggests that NK cells play a critical role in the immune function of the fiver and in the immune defenses against HCC, indicating that HCC might be an ideal target for NK cell-based immunotherapies. To obtain comprehensive insights into the putative influence of NK cells on HCC, this paper summarizes current knowledge on NK cells in HCC and discusses the usefulness and prospects of NK cell-based immunotherapies. Critical issues that require consideration for the successful clinical translation of NK cell-based therapies are also addressed. If appropriately used and further optimized, NK cell- based therapies could dominate important roles in the future immunotherapeutic market of HCC.

关键词： natural killer cell hepatocellular carcinoma immunotherapy