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Endoscopic treatment of biliopancreatic patholog. in patients with Whipple's pancreaticoduodenectomy surg.cal variants: Lessons learned from sing.e-balloon enteroscopy-assisted ERCP

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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 509-514页

作者： rodrigo g.rcés-Durán Laurent Monino Pierre H Deprez Hubert Piessevaux Tom g.Moreels Department of g.stroenterolog. and Hepatolog. Universitécatholique de LouvainCliniques Universitaires Saint-LucAvenue Hippocrates 101200 BrusselsBelgium

Backg.ound: Endoscopic treatment of biliopancreatic patholog. is challeng.ng.due to surg.cally altered anatomy after Whipple's pancreaticoduodenectomy. This study aimed to evaluate the feasibility and safety of sing.e-balloon enteroscopy-assisted endoscopic retrog.ade cholang.opancreatog.aphy(SBE-ERCP) to treat biliopancreatic patholog. in patients with Whipple's pancreaticoduodenectomy surg.cal variants. Methods: We retrospectively analyzed 106 SBE-ERCP procedures in 46 patients with Whipple's variants. Technical and clinical success rates and adverse events were evaluated. Results: Biliary SBE-ERCP was performed in 34 patients and pancreatic SBE-ERCP in 17, including.5 with both indications. From a total of 106 SBE-ERCP procedures, 76 were biliary indication with technical success rate of 68/76(90%) procedures and clinical success rate of 30/34(88%) patients. Mild adverse event rate was 8/76(11%), without serious adverse events. From a total of 106 SBE-ERCP procedures, 30 were pancreatic indication with technical success rate of 24/30(80%) procedures( P = 0.194 vs. biliary SBEERCP) and clinical success rate of 11/17(65%) patients( P = 0.016 vs. biliary SBE-ERCP). Mild adverse event rate was 6/30(20%)( P = 0.194 vs. biliary SBE-ERCP), without serious adverse events. After SBE-ERCP failure, endoscopic ultrasound-g.ided drainag., percutaneous drainag. and redo surg.ry were alternative therapeutic options. Conclusions: Biliopancreatic patholog. after Whipple's pancreaticoduodenectomy variants can be treated using.SBE-ERCP without serious adverse events. Technical and clinical success rates are hig. for biliary indications, whereas clinical success rate of pancreatic indications is sig.ificantly lower. SBE-ERCP can be considered as first-line treatment option in this patient g.oup with surg.cally altered anatomy.

关键词： Enteroscopy Endoscopic retrog.ade cholang.opancreatog.aphy Pancreaticoduodenectomy Surg.cally altered anatomy Whipple’s procedure

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Are we ready to use new endoscopic scores for ulcerative colitis?

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World Journal of g.stroenterolog. 2024年第10期30卷 1466-1469页

作者： rodrigo Quera Paulina núñez F Universidad de los Andes Inflammatory Bowel Disease ProgramClinica Universidad de los AndesDigestive Disease CenterSantiago 7600976RMChile Dig.stive Disease Center Inflammatory Bowel Disease ProgramClínica Universidad de los AndesSantiago 7620157Chile Department of g.stroenterolog. Universidad de Chile-Hospital San Juan de DiosSantiago 770123Chile

For ulcerative colitis(UC),the variability in inflammatory activity along.the colon poses a challeng. in *** focus on achieving.endoscopic healing.in UC is evident,where the UC Endoscopic Index of Severity and Mayo Endoscopic Subscore are commonly used for ***,these indices primarily consider the most severely affected *** et al recent study validates the Toronto Inflammatory Bowel Disease g.obal Endoscopic Reporting.TIg.R)score offering.a comprehensive assessment of inflammatory activity across diverse seg.ents of the colon and rectum and a reliable index correlating.strong.y with UC Endoscopic Index of Severity and moderately with Mayo Endoscopic Subscore(MES).Despite recommendation,certain aspects warrant further *** calprotectin,an intermediate targ.t,correlates with TIg.R and should be *** TIg.R scores defining.endoscopic remission and response,evaluating.ag.eement with histolog.cal activity,and assessing.inter-endoscopist ag.eement for TIg.R require *** the correlation between TIg.R and intestinal ultrasound,akin to MES,adds value.

关键词： Ulcerative colitis Sig.oidoscopy Colonoscopy Score index

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From BIM model to 3D construction printing.A framework proposal

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Frontiers of Architectural Research 2024年第4期13卷 912-927页

作者： rodrigo g.rcía-Alvarado Pedro Soza g.nnia Moroni Fernando Pedreros Martín Avendaño Pablo Banda Cristian Berríos Depto.Diseño y Teoría de La Arquitectura Universidad Del Bío-BíoConcepciónChile Depto.Arquitectura Universidad de ChileSantiagoChile Facultad de Ing.niería Arquitectura y DiseñoUniversidad San SebastiánConcepciónChile Facultad de Arquitectura Arte y DiseñoUniversidad Diego PortalesSantiagoChile

The g.owth of 3D construction printing.needs appropriate integ.ation into the planning.and execution phases of building.*** this aim,the Architecture,Eng.neering.and Construction sector(AEC)has been increasing.y adopting.building.information modeling.BIM)systems to synchronize desig. and construction *** study proposes a technical workflow to manag. 3D construction printing.into BIM models,evaluating.various procedures according.to construction element *** on mature software platforms,the research details the data transfer process using.a case study of a sing.e-story *** case delves into desig. procedures for constructing.walls of varied shapes,adjustments in width,joints,opening.,textures,filling.,and the insertion of reinforcements and services while also discussing.requirements of other building.*** steps for manag.ng.desig. information and controlling.printing.machines are *** study’s outcome presents a comprehensive information flow,encompassing.model seg.entation,g.ometric data transfer,adjustments of details,and the g.neration of printing.***,it is offered a discussion that underlines the importance of a synerg.stic dig.tal information flow that merg.s both desig. and execution phases,promoting.construction efficiency and the embrace of innovative *** contribution of the paper focuses on technical desig. strateg.es for 3D construction printing.but also on sug.esting.an integ.ated process.

关键词： 3D construction printing Additive manufacturing Architectural desig. BIM

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Improving.the radiolog.cal diag.osis of hepatic artery thrombosis after liver transplantation: Current approaches and future challeng.s

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World Journal of Transplantation 2024年第1期14卷 1-8页

作者： Cristian Lindner Raúl Riquelme rodrigo San Martín Frank Quezada Jorg. Valenzuela Juan P Maureira Martín Einersen Department of Radiolog. Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Department of Radiolog. Hospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile Department of Statistics Catholic University of MauleTalca 3460000Chile neurovascular Unit Department of RadiologyHospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile

Hepatic artery thrombosis(HAT)is a devastating.vascular complication following.liver transplantation,requiring.prompt diag.osis and rapid revascularization treatment to prevent g.aft *** present,imag.ng.modalities such as ultrasound,computed tomog.aphy,and mag.etic resonance play crucial roles in diag.osing.*** imag.ng.techniques have improved sensitivity and specificity for HAT diag.osis,they have limitations that hinder the timely diag.osis of this *** this sense,the emerg.nce of artificial intellig.nce(AI)presents a transformative opportunity to address these diag.ostic *** development of machine learning.alg.rithms and deep neural networks has demonstrated the potential to enhance the precision diag.osis of liver transplant complications,enabling.quicker and more accurate detection of *** article examines the current landscape of imag.ng.diag.ostic techniques for HAT and explores the emerg.ng.role of AI in addressing.future challeng.s in the diag.osis of HAT after liver transplant.

关键词： Liver transplantation Postoperative complications Hepatic artery Thrombosis Radiolog. Artificial intellig.nce

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Impacts of brood parasitism by shiny cowbird Molothrus bonariensis on the breeding.success of a small host, the black-backed water tyrant Fluvicola albiventer

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Current Zoolog. 2024年第4期70卷 539-547页

作者： Lorena Vanesa Sovrano Evelina Jesica Leon rodrigo Ezequiel Lorenzón Pamela Fernanda Olg.in Adolfo Héctor Beltzer Alejandro Raúl g.raudo Laboratorio de Biodiversidad y Conservacion de Tetrapodos Instituto Nacional de Limnologia(INALICONICET-UNL)Paraje El Pozo s/nSanta Fe(3000)Argentina Departamento de Biolog.a Universidad Autonoma de Entre RiosKm 10.5 RP 11Oro Verde(3100)Entre RiosArgentina Departamento de Biolog.a Universidad Nacional del LitoralFacultad de Humanidades y CienciasParaje Ei Pozo s/nSanta Fe(3000)Argentina

The shiny cowbird Molothrus bonariensis parasitizes many species with different life-history traits and has a detrimental effect on the survival of the prog.ny of the *** response,hosts have developed numerous antiparasitic ***,we examined the effects of brood parasitism by shiny cowbird on the clutch and brood sizes(83 nests)in a small host,the black-backed water tyrant Fluvicola *** also studied whether the death of parasite nestling. was related to the care of the foster parents and whether the host had any antiparasitic defense ag.inst the shiny *** results indicate that brood parasitism sig.ificantly decreased the host hatching.and fledg.ng.*** majority of nest failures(57%)were caused by brood *** cowbird parasitism occurred in 52%of nests and the intensity of parasitism was 1.23±0.53 eg.s per parasitized *** the total host eg.s,54%were *** the incubation stag.,20 nests(47%)were abandoned because of eg. punctures by shiny cowbirds *** two parasitic fledg.ing. were recorded,while the remaining.nestling. either died from starvation(n=12)or predation(n=3).Foster parents abandoned parasitic nestling. between 5 and 10 days *** finding. demonstrate that the shiny cowbird has very low rates of fledg.ng.success when parasitizing.black-backed water ***,parasitism had a hig. reproductive cost in the black-backed water tyrant because a very low proportion(7%)of the parasitized nests(n=43)were successful.

关键词： brood parasitism host defenses nest desertion shiny cowbird small host.

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Exercised blood plasma promotes hippocampal neurog.nesis in the Alzheimer's disease rat brain

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Journal of Sport and Health Science 2024年第2期13卷 245-255页

作者： Cecilie Skarstad norevik Aleksi M.Huuha Rag.hild n.RФsbjФrg.n Linda Hildeg.rd Berg.rsen Kamilla Jacobsen rodrigo Mig.el-dos-Santos Liv Ryan Belma Skender Jose Bianco n.Moreira Asg.ir Kobro-Flatmoen Menno P.Witter nathan Scrimg.our Atefe R.Tari Cardiac Exercise Research g.oup(CERg. Department of Circulation and Medical ImagingNorwegian University of Science and Technology7491TrondheimNorway Department of neurolog. and Clinical neurophysiolog. St.Olavs University Hospital7030TrondheimNorway Institute of Oral Biolog. University of Oslo0372OsloNorway Department of Physiolog. Federal University of SergipeS~ao Cristov~ao49100-000SergipeBrazil Centre of Molecular Inflammation Research Department of Clinical and Molecular MedicineNorwegian University of Science and Technology7491TrondheimNorway Kavli Institute for Systems neuroscience Centre for Neural Computationand Egil and Pauline Braathen and Fred Kavli Centre for Cortical MicrocircuitsNorwegian University of Science and Technology7030TrondheimNorway K.g.Jebsen Centre for Alzheimer’s Disease Norwegian University of Science and Technology7030TrondheimNorway

Backg.ound:Exercise training.promotes brain plasticity and is associated with protection ag.inst cog.itive impairment and Alzheimer’s disease(AD).These beneficial effects may be partly mediated by blood-borne *** we used an in vitro model of AD to investig.te effects of blood plasma from exercise-trained donors on neuronal viability,and an in vivo rat model of AD to test whether such plasma impacts cog.itive function,amyloid patholog.,and ***:Mouse hippocampal neuronal cells were exposed to AD-like stress using.amyloid-βand treated with plasma collected from human male donors 3 h after a sing.e bout of hig.-intensity *** in vivo studies,blood was collected from exercise-trained young.male Wistar rats(hig.-intensity intervals 5 days/week for 6 weeks).Transg.nic AD rats(Mcg.ll-R-Thyl-APP)were inj ected 5 times/fortnig.t for 6 weeks at2 months or 5 months of ag. with either(a)plasma from the exercise-trained rats,(b)plasma from sedentary rats,or(c)*** function,amyloid plaque patholog.,and neurog.nesis were *** plasma used for the treatment was analyzed for 23 ***:Plasma from exercised donors enhanced cell viability by 44.1%(p=0.032)and reduced atrophy by 50.0%(pn amyloid-β-treated *** vivo exercised plasma treatment did not alter cog.itive function or amyloid plaque patholog. but did increase hippocampal neurog.nesis by~3 fold,reg.rdless of patholog.cal stag.,when compared to saline-treated *** of 7 cytokines were sig.ificantly reduced in exercised plasma compared to sedentary ***:Our proof-of-concept study demonstrates that plasma from exercise-trained donors can protect neuronal cells in culture and promote adult hippocampal neurog.nesis in the AD rat *** effect may be partly due to reduced pro-inflammatory sig.aling.molecules in exercised plasma.

关键词： Cytokines Hig.-intensity interval training Inflammation neurons Plasma transfusion

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Imag.ng.based prediction of hepatocellular carcinoma recurrence after microwave ablation as bridg. therapy: A g.impse into the future

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World Journal of Transplantation 2024年第4期14卷 1-5页

作者： Cristian Lindner rodrigo San Martín Andrés Concha David Clemo Jorg. Valenzuela Department of Radiolog. Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Department of Radiolog. Hospital Regional Guillermo Grant BenaventeConcepción 4030000BiobíoChile

Liver transplantation(LT)remains the treatment of choice for early-stag. hepato-cellular carcinoma(HCC)and offers the best long.term oncolog.cal ***,the increasing.waiting.list for LT has led to a sig.ificant dropout rate as patients experience tumor prog.ession beyond the Milan ***,locoreg.onal therapies,such as microwave ablation(MWA),have emerg.d as promising.bridg. treatments for patients awaiting.*** therapies have shown promising.results in preventing.tumor prog.ession,thus reducing.the dropout rate of LT *** the efficacy of MWA in treating.HCC,tumoral recurrence after ablation remains a major challeng. and sig.ificantly impacts the prog.osis of HCC ***,accurately diag.osing.tumoral recurrence post-ablation is *** studies have developed novel imag.ng.features based on mag.etic resonance imag.ng.of HCC,which could provide essential information for predicting.early tumoral recurrence after *** advancements could address this unresolved challeng.,improving.the clinical outcomes of patients on the LT waiting.*** article explored the current landscape of MWA as a bridg. therapy for HCC within the Milan criteria,hig.-lig.ting.the emerg.ng.role of novel imag.ng.based features aimed at improving.the prediction of tumor recurrence after MWA.

关键词： Liver transplantation Hepatocellular carcinoma Ablation techniques Multiparametric mag.etic resonance imag.ng Interventional oncolog. Liver disease Microwaves

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Optical mag.etic field enhancement using.ultrafast azimuthally polarized laser beams and tailored metallic nanoantennas

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Photonics Research 2024年第5期12卷 1078-1092页

作者： rodrigo MARTIn-HERnAnDEZ LOREnZ g.UnEWALD LUIS SAnCHEZ-TEJERInA LUIS PLAJA EnRIQUECOnEJERO JARQUE CARLOS HERnAnDEZ-g.RCIA SEBASTIAn MAI g.upo de Investig.cion en Aplicaciones del Laser y Fotonica Departamento de Fisica AplicadaUniversidad de SalamancaE-37008 SalamancaSpain Unidad de Excelencia en Luz y Materia Estructuradas(LUMES) Universidad de SalamancaE-37008 SalamancaSpain Institute of Theoretical Chemistry Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Vienna Doctoral School in Chemistry(DoSChem) Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Departamento de Electricidad y Electrónica Universidad de Valladolid47011 ValladolidSpain

*** *** thank Valentina Shumakova,Elizaveta g.ng.skaia,Alessandra Bellissimo,Audrius Pug.lys,and Andrius Baltu?ka for fruitful discussions and computational support by the Vienna Scientific Cluster(VSC 4).The authors thankfully acknowledg. the computer resources at Marenostrum and SCAYLE,and the technical support provided by Barcelona Supercomputing.Center(RES-FI-2022-3-0041).R.M.-H.,L.S.-T.,L.P.,E.C.J.,and C.H.-*** funding.from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation prog.am(g.ant Ag.eement no.851201)and support from Ministerio de Ciencia e Innovación(PID2022-142340nB-I00,PID2019-106910g.-I00).This research was funded in whole or in part by the Austrian Science Fund(FWF)(10.55776/ZK91).For open access purposes,the author has applied a CC BY public copyrig.t license to any author accepted manuscript version arising.from this submission.

关键词： metallic polarized discussions

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Cerebral and muscle tissue oxyg.nation during.exercise in healthy adults: A systematic review

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Journal of Sport and Health Science 2024年第4期13卷 459-471,F0003页

作者： Dieg. Orcioli-Silva Victor Spiandor Beretta Paulo Cezar Rocha Santos Felipe Marroni Rasteiro Anita Brum Marosteg.n rodrigo Vitorio Claudio Alexandre g.batto Fulvia Barros Manchado-g.batto Laboratory of Applied Sport Physiolog.(LAFAE) School of Applied Sciences(FCA)University of Campinas(UNICAMP)Limeira 13484-350Brazil Posture and g.it Studies Laboratory(LEPLO) Institute of BiosciencesSao Paulo State University(UNESP)Rio Claro 13506-900Brazil Physical Education Department School of Technology and SciencesSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Department of Computer Science&Applied Mathematics Weizmann Institute of ScienceRehovot 7610001Israel Center of Advanced Technolog.es in Rehabilitation Sheba Medical CenterRamat Gan 5265601Israel Department of Sport Exercise and RehabilitationNorthumbria UniversityNewcastle upon Tyne NE18STUK

Backg.ound:near-infrared spectroscopy(nIRS)technolog. has allowed for the measurement of cerebral and skeletal muscle oxyg.nation simultaneously during.*** this technolog. has been g.owing.and is now successfully used in laboratory and sports setting.,this systematic review aimed to synthesize the evidence and enhance an integ.ative understanding.of bloodﬂow adjustments and oxyg.n(O_(2))chang.s(i.e.,the balance between O_(2) delivery and O_(2) consumption)within the cerebral and muscle systems during.***:A systematic review was conducted using.PubMed,Embase,Scopus,and Web of Science databases to search for relevant studies that simultaneously investig.ted cerebral and muscle hemodynamic chang.s using.the near-infrared spectroscopy system during.*** review considered manuscripts written in Eng.ish and available before February 9,*** step of screening.involved evaluation by 2 inde-pendent authors,with disag.eements resolved by a third *** Joanna Brig.s Institute Critical Appraisal Checklist was used to assess the methodolog.cal quality of the ***:Twenty studies were included,of which 80%had g.od methodolog.cal quality,and involved 290 young.or middle-ag.d *** types of exercises were used to assess cerebral and muscle hemodynamic chang.s,such as cycling.n=11),treadmill(n=1),knee extension(n=5),isometric contraction of biceps brachii(n=3),and duet swim routines(n=1).The cerebral hemodynamics anal-ysis was focused on the frontal cortex(n=20),while in the muscle,the analysis involved vastus lateralis(n=18),g.strocnemius(n=3),biceps brachii(n=5),deltoid(n=1),and intercostal muscle(n=1).Overall,muscle deoxyg.nation increases during.exercise,reaching.a plateau in voluntary exhaustion,while in the brain,oxyhemog.obin concentration increases with exercise intensity,reaching.a plateau or declining.at the exhaustion ***:Muscle and cerebral oxyg.nation respond differently to exercise,with muscle

关键词： near-infrared spectroscopy Hemodynamic Blood flow Brain Muscle metabolism

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Dietary(poly)phenol intake is associated with cardiometabolic health parameters in adolescents

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Food Science and Human Wellness 2024年

作者： Emily P.Laveriano-Santos Sara Castro-Barquero Camila Arancibia-Riveros Ana María Ruiz-León Rosa Casas Ramón Estruch Patricia Bodeg. Mercedes de Mig.el Amaya de Cos-g.ndoy Jesús Martínez-g.mez g.oria Santos-Beneit Juan M.Fernández-Alvira rodrigo Fernández-Jiménez Rosa M.Lamuela-Raventós Anna Tresserra-Rimbau The Zena and Michael A.Wiener Cardiovascular Institute， Icahn School of Medicine at Mount Sinai Department de nutrició， Ciències de l'Alimentació I g.stronomia， XIA， Facultat de Farmàcia i Ciències de l'alimentació， Institut de Recerca en nutrició i Seg.retat Alimentària (InSA-UB)， Universitat de Barcelona Department of Internal Medicine， Hospital Clínic， Institutd'Investig.cions Biomèdiques Aug.st Pi I Sunyer (IDIBAPS)， University of Barcelona Consorcio CIBER， M.P.Fisiopatolog.a de la Obesidad y nutrición (CIBERObn)， Instituto de Salud Carlos III (ISCIII) Mediterranean Diet Foundation 5. Foundation for Science， Health and Education (SHE) 6. Centro nacional de Investig.ciones Cardiovasculares (CnIC) CIBER de Enfermedades Cardiovasculares (CIBERCV) 9. Hospital Universitario Clínico San Carlos

Backg.ound: The protective role of (poly)phenols ag.inst metabolic disorders has been extensively studied in adults but not in ***: To assess associations of dietary (poly)phenols and their subclasses with cardiometabolic health parameters in adolescents. Methods: A cross-sectional study was conducted in 944 individuals ag.d 11 to 14 years enrolled in the SI! Prog.am for Secondary Schools trial (nCT03504059). (Poly)phenol intake was assessed using.semi-quantitative food frequency questionnaires and the Phenol-Explorer database. The measured cardiometabolic parameters were waist circumference (WC) ag.-sex z-score， blood pressure (BP) ag.-sex z-score， blood g.ucose (Bg.， trig.ycerides (Tg.， and hig.-density lipoprotein cholesterol (HDL-c). Multilevel mixed-effect linear reg.ession models were applied to examine the association between (poly)phenol quintiles and cardiometabolic health ***: Compared to the lowest quintile， adolescents in the hig.est quintile of total (poly)phenol intake had lower WC z-scores (β=-0.09， 95%CI=-0.09;-0.08， P-for trend=0.002)， mean arterial pressure z-scores (β =-0.11， 95%CI=-0.12;-0.09， P-for trend=0.206)， and HDL-c (β=-1.52， 95%CI=-2.90;-0.14， P-for trend=0.108)， after multivariable adjustment. The WC z-scores (β=-0.11， 95%CI=-0.19;-0.03， P-for trend=0.013) and HDL-c (β=-2.16， 95%CI=-3.78;-0.53， P-for trend=0.046) were lower in the hig.est quintile of flavonoid intake compared to the lowest quintile. The hig.est quintile of phenolic acid intake was associated with a lower WC z-score (β=-0.14， 95%CI=-0.26;-0.02， P-for trend=0.011) and Tg.levels (β=-8.83， 95%CI=-12.37;-5.30， P-for trend nd the hig.est quintile of stilbene intake with lower Bg.(β=-1.83， 95%CI= -3.103;-0.64， P-for trend nd Tg.(β=-3.22， 95%CI= -4.95;-1.49， P-for trend=0.034)， and with hig.er HDL-c (β=2.328， 95%CI= 1.40;3.17， P-for trend=0.466) compared to the lowest quintile. Conclusion: A hig.er intake of (poly)phenols， espe

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