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Biomechanics of Musculoskeletal System and Its Biomimetic Implications： A Review

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Journal of Bionic Engineering 2014年第2期11卷 159-175页

作者： lei ren Zhihui Qian Luquan ren School of Mechanical Aerospace and Civil Engineering University of Manchester Manchester M13 9PL UK Key Laboratory of Bionic Engineering (Ministry of Education China) Jilin University Changchun 130022 P. R. China

Biological musculoskeletal system （MSK）, composed of numerous bones, cartilages, skeletal muscles, tendons, ligaments etc., provides form, support, movement and stability for human or animal body. As the result of million years of selection and evolution, the biological MSK evolves to be a nearly perfect mechanical mechanism to support and transport the human or animal body, and would provide enormously rich resources to inspire engineers to innovate new technology and methodology to develop robots and mechanisms as effective and economical as the biological systems. This paper provides a general review of the current status of musculoskeletal biomechanics studies using both experimental and computational methods. This includes the use of the latest three-dimensional motion analysis systems, various medical imaging modalities, and also the advanced rigid-body and continuum mechanics musculoskeletal modelling techniques. Afterwards, several representative biomimetic studies based on ideas and concepts inspired from the structures and biomechanical functions of the biological MSK are dis- cussed. Finally, the major challenges and also the future research directions in musculoskeletal biomechanics and its biomimetic studies are proposed.

关键词： musculoskeletal system biomechanics multi-scale biomimetics biologically inspired robots and mechanisms

The influence of different functional areas on customers’thermal comfort-A Field study in shopping complexes of North China

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Energy and Built Environment 2023年第3期4卷 297-307页

作者： Xingyu Zang Kuixing Liu Ye Qian Guanhua Qu Ye Yuan lei ren Gang Liu Tianjin International Engineering Institute Tianjin UniversityTianjin 300072China School of Architecture Tianjin UniversityTianjin 300072China Tianjin Key Laboratory of Architectural Physical Environment and Ecological Technologies Tianjin UniversityTianjin 300072China

Shopping complexes are widely built for their convenience and multiple ***,their complex func-tional areas,result in significantly different thermal environments and various customers’thermal *** explain the influence of functional related parameters on the thermal perception of customers in shopping com-plexes,we selected two typical functional related parameters,including customers’thermal expectation level of indoor environment in their current area and the area where the customer was ten minutes before taking the sur-vey.851 valid questionnaires were obtained in two typical shopping complexes during ***’thermal neutral temperature,thermal preference temperature and thermal comfort temperature range were calculated in different functional ***’thermal expectation level was quantified by using expectancy *** results showed that customers’thermal expectation level in entertainment areas was the highest,followed by food courts,retail areas,and transition ***’thermal expectation level would influence their thermal neutral temperature and thermal *** with different thermal experience differed sig-nificantly in their thermal sensation voting(p<0.01).The highest thermal sensitivity,about 0.41/°C,was found in customers moving from high-temperature areas to low-temperature *** findings help to clarify how functional related parameters affect the thermal comfort of customers and provide the guidance for designing the indoor temperature in shopping complexes.

关键词： Shopping complexes Field study Thermal comfort Thermal expectation level Expectancy factor Thermal experience

高密度电法在秦皇岛地区岩溶勘察工作中的应用

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矿产勘查 2024年第S01期15卷 358-363页

作者：李春波张丽任磊于蒙代涛李福庆华北地质勘查局五一九大队河北保定071051 河北九华勘查测绘有限责任公司河北保定071051

高密度电法是一种技术成熟、抗干扰能力强、分辨率高、成本低、施工方便的物探方法,被广泛应用于岩溶勘察工作中。为查明秦皇岛某施工场地的岩溶分布及发育情况,采用高密度电法进行岩溶探测,同时进行了钻探验证。结果表明:通过高密度电... 详细信息

高密度电法是一种技术成熟、抗干扰能力强、分辨率高、成本低、施工方便的物探方法,被广泛应用于岩溶勘察工作中。为查明秦皇岛某施工场地的岩溶分布及发育情况,采用高密度电法进行岩溶探测,同时进行了钻探验证。结果表明:通过高密度电法能较好地识别地层结构、浅部低阻异常,以石灰岩高阻界面上呈现的“下凹”趋势或“凹槽”为岩溶特征共圈定出岩溶异常22处,对其中的2处异常进行了钻探验证,钻探结果与物探解译结果对应良好,可见在秦皇岛地区利用高密度电法进行岩溶勘察是有效的。本研究可为秦皇岛地区岩溶勘察提供一定的借鉴。

关键词：高密度电法岩溶勘察溶洞钻探验证秦皇岛

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老年重症肺炎并发ARDS患者血清miR-27a、FOXO3与疾病严重程度及预后的关系

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疑难病杂志 2024年第3期23卷 302-307,322页

作者：金娴邵振华何梅姜俊王志安任蕾上海市静安区中心医院重症医学科 200040 上海市同济医院呼吸与危重症科 200065 上海市第四康复医院呼吸康复科 200040

目的分析老年重症肺炎并发急性呼吸窘迫综合征(ARDS)患者血清微小核糖核酸(miRNA)-27a、叉头框蛋白O3(FOXO3)与疾病严重程度及预后的关系。方法选取2022年10月—2023年9月上海市静安区中心医院重症医学科收治老年重症肺炎并发ARDS患者10... 详细信息

目的分析老年重症肺炎并发急性呼吸窘迫综合征(ARDS)患者血清微小核糖核酸(miRNA)-27a、叉头框蛋白O3(FOXO3)与疾病严重程度及预后的关系。方法选取2022年10月—2023年9月上海市静安区中心医院重症医学科收治老年重症肺炎并发ARDS患者108例(ARDS组)和老年重症肺炎未并发ARDS患者72例(非ARDS组),ARDS组患者再根据氧合指数分为轻度亚组26例、中度亚组34例、重度亚组48例,并根据28 d预后情况分为死亡亚组33例、存活亚组75例;另选取同期体检健康志愿者60例为健康对照组。采用实时荧光定量聚合酶链式反应检测血清miR-27a、FOXO3水平,TargetScan数据库预测miR-27a与FOXO3的结合位点。通过Pearson/Spearman相关性分析血清miR-27a与FOXO3 mRNA水平的相关性,多因素Logistic回归分析老年重症肺炎并发ARDS患者预后的影响因素,受试者工作特征(ROC)曲线分析血清miR-27a、FOXO3 mRNA水平对老年重症肺炎并发ARDS患者死亡的预测价值。结果健康对照组、非ARDS组、ARDS组血清miR-27a水平依次降低,FOXO3 mRNA水平依次升高(F/P=77.352/<0.001、62.956/<0.001);轻度亚组、中度亚组、重度亚组血清miR-27a水平依次降低,FOXO3 mRNA水平依次升高(F/P=83.597/<0.001、111.833/<0.001);miR-27a与FOXO3的3’-非翻译区3257~3264处存在结合位点。老年重症肺炎并发ARDS患者血清miR-27a与FOXO3 mRNA水平呈负相关(r/P=-0.736/<0.001),氧合指数与血清miR-27a水平呈正相关,与FOXO3 mRNA水平呈负相关(r/P=0.751/<0.001、-0.785/<0.001)。老年重症肺炎并发ARDS患者28 d死亡率为30.56%(33/108)。年龄增加、机械通气时间延长、FOXO3 mRNA升高为影响老年重症肺炎并发ARDS患者预后的独立危险因素[OR(95%CI)=1.199(1.033~1.393)、1.547(1.009~2.373)、1.108(1.040~1.180)],氧合指数升高、miR-27a升高为独立保护因素[OR(95%CI)=0.973(0.958~0.989)、0.903(0.844~0.965)];血清miR-27a、FOXO3 mRNA水平及二者联合预测老年重症肺炎并发ARDS患者死亡的曲线下面积分别为0.784、0.786、0.879,二者联合的AUC大于血清miR-27a、FOXO3 mRNA水平单独预测(Z/P=2.550/0.011、2.963/0.003)。结论老年重症肺炎并发ARDS患者血清miR-27a水平降低,FOXO3 mRNA水平升高,与疾病加重和预后不良密切相关,二者联合预测老年重症肺炎并发ARDS患者死亡的价值较高。

关键词：重症肺炎急性呼吸窘迫综合征微小核糖核酸-27a 叉头框蛋白O3 疾病严重程度预后老年人

全方位优化护理在经桡动脉穿刺行CAG检查及PCI患者中的应用效果

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保健医学研究与实践 2024年第6期21卷 123-127页

作者：郝春艳高纯纯唐丽丽宁彬任磊安徽省阜阳市人民医院/安徽医科大学附属阜阳人民医院心脏重症监护病区安徽阜阳236000 安徽省阜阳市人民医院/安徽医科大学附属阜阳人民医院心血管内科安徽阜阳236000

目的探讨全方位优化护理预防经桡动脉穿刺行冠状动脉造影(CAG)检查及经皮冠状动脉介入治疗(PCI)患者术后穿刺部位渗血的效果。方法选取2021年2月—2023年3月阜阳市人民医院收治的118例经桡动脉穿刺行CAG检查及PCI的患者作为研究对象,采... 详细信息

目的探讨全方位优化护理预防经桡动脉穿刺行冠状动脉造影(CAG)检查及经皮冠状动脉介入治疗(PCI)患者术后穿刺部位渗血的效果。方法选取2021年2月—2023年3月阜阳市人民医院收治的118例经桡动脉穿刺行CAG检查及PCI的患者作为研究对象,采用随机数字表法分为对照组和观察组,每组59例。对照组患者围手术期接受常规护理干预,观察组患者围手术期接受全方位优化护理干预,比较2组患者术后出血情况、疼痛程度、舒适度以及护理满意度。结果观察组患者术后出血发生率为3.38%(2/59),低于对照组的13.55%(8/59),差异有统计学意义(χ2=3.933,P=0.047)。2组患者干预前疼痛数字评分法(NRS)评分比较,差异无统计学意义(P>0.05);2组患者干预后NRS评分均高于干预前,但观察组低于对照组,差异均有统计学意义(P0.05);2组患者干预后GCQ各维度评分及总分均高于干预前,且观察组均高于对照组,差异均有统计学意义(P<0.05)。观察组患者住院病人护理满意度量表的服务质量、环境设施、结果3个维度评分及总分均高于对照组,差异均有统计学意义(P<0.05)。结论全方位优化护理可显著减少经桡动脉穿刺行CAG及PCI患者术后穿刺部位渗血情况、减轻疼痛程度并提升患者舒适度及护理满意度,具有良好的临床应用价值。

关键词：经桡动脉穿刺经皮冠状动脉介入治疗冠状动脉造影穿刺部位渗血

Enhancing betavoltaic nuclear battery performance with 3D P^(+)PNN^(+)multi-groove structure via carrier evolution

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Nuclear Science and Techniques 2023年第12期34卷 1-16页

作者： Hou‑Jun He Yun‑Cheng Han Xiao‑Yu Wang Yu‑Min Liu Jia‑Chen Zhang lei ren Ming‑Jie Zheng Hefei Institutes of Physical Science Chinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China School of Nuclear Technology and Chemistry and Biology Hubei University of Science and TechnologyXianning 437100China

Betavoltaic nuclear batteries offer a promising alternative energy source that harnesses the power of beta particles emitted by *** satisfy the power demands of microelectromechanical systems(MEMS),3D structures have been proposed as a potential ***,this paper introduces a novel 3D^(63)Ni–SiC-based P^(+)PNN^(+)structure with a multi-groove design,avoiding the need for PN junctions on the inner surface,and thus reducing leakage current and power *** Carlo simulations were performed considering the fully coupled physical model to extend the electron–hole pair generation rate to a 3D structure,enabling the efficient design and development of betavoltaic batteries with complex 3D *** a result,the proposed model produces the significantly higher maximum output power density of 19.74μW/cm^(2) and corresponding short-circuit current,open-circuit voltage,and conversion efficiency of 8.57μA/cm^(2),2.45 V,and4.58%,respectively,compared with conventional planar *** analysis of the carrier transport and collection characteristics using the COMSOL Multiphysics code,we provide deep insights regarding power increase,and elucidate the discrepancies between the ideal and simulated performances of betavoltaic *** work offers a promising approach for the design and optimization of high-output betavoltaic nuclear batteries with a unique 3D design,and serves as a valuable reference for future device fabrication.

关键词： Betavoltaic nuclear battery High-output power density Three-dimensional structure Carrier drift–diffusion Carrier recombination Carrier collection efficiency

In vivo noninvasive study of diabetic peripheral neuropathy plantar morphology and mechanical properties based on ultrasound

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Chinese Medical Journal 2023年第22期136卷 2762-2764页

作者： Qiang Zhou Ying Li lei ren Boxin Yu Xiao Zhang Zhihui Qian Jianan Wu Ruixia Xu Jing Liu Luquan ren Key Laboratory of Bionic Engineering Ministry of EducationJilin UniversityChangchunJilin 130025China Department of General Practice The First Hospital of Jilin UniversityChangchunJilin 130021China Editorial Department of Journal of Bionic Engineering Jilin UniversityChangchunJilin 130022China School of Medical Informatics and Engineering Xuzhou Medical UniversityXuzhouJiangsu 221004China

To the Editor:The incidence of diabetes complications increases with the increase in diabetes *** peripheral neuropathy(DPN)is one of the most common complications in diabetes *** is very harmful and is an important cause of diabetic foot and *** amputation rate of DPN patients is 10-20 times higher than that of nondiabetic *** 30 s,somewhere in the world,a patient’s lower limb or part of a lower limb will be surgically amputated due to DPN.[1]DPN seriously interferes with the physical and mental health of *** the same time,the high cost of treatment and rehabilitation care also causes huge economic pressure on ***,it is particularly important to identify,diagnose,and prevent DPN in the early or ultra-early stage.

关键词： diabetic neuropathy patients

Dynamic Stability of Passive Bipedal Walking on Rough Terrain： A Preliminary Simulation Study

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Journal of Bionic Engineering 2012年第4期9卷 423-433页

作者： Parsa Nassiri Afshar lei ren School of Mechanical Aerospace and Civil Engineering University of Manchester Manchester M13 9PL UK Key Laboratory of Bionic Engineering (Ministry of Education China) Jilin University Changehun 130022 P.R. China

A simplified 2D passive dynamic model was simulated to walk down on a rough slope surface defined by deterministic profiles to investigate how the walking stability changes with increasing surface roughness. Our results show that the passive walker can walk on rough surfaces subject to surface roughness up to approximately 0.1% of its leg length. This indicates that bipedal walkers based on passive dynamics may possess some intrinsic stability to adapt to rough terrains although the maxi- mum roughness they can tolerate is small. Orbital stability method was used to quantify the walking stability before the walker started to fall over, It was found that the average maximum Floquet multiplier increases with surface roughness in a non-linear form. Although the passive walker remained orbitally stable for all the simulation cases, the results suggest that the possibility of the bipedal model moving away from its limit cycle increases with the surface roughness if subjected to additional perturbations. The number of consecutive steps before falling was used to measure the walking stability after the passive walker started to fall over. The results show that the number of steps before falling decreases exponentially with the increase in surface roughness. When the roughness magnitude approached to 0.73% of the walker＇s leg length, it fell down to the ground as soon as it entered into the uneven terrain. It was also found that shifting the phase angle of the surface profile has apparent affect on the system stability. This is probably because point contact was used to simulate the heel strikes and the resulted variations in system states at heel strikes may have pronounced impact on the passive gaits, which have narrow basins of attraction. These results would provide insight into how the dynamic stability of passive bipedal walkers evolves with increasing surface roughness.

关键词： bipedal walking rough terrain dynamic stability human locomotion

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可实现隐私保护的容错聚合签名方案

宝鸡文理学院学报（自然科学版） 2024年第2期44卷 12-19页

作者：任蕾杜红珍尤毅晨刘珂何利平宝鸡文理学院数学与信息科学学院陕西宝鸡721013

目的为车联网中车辆与路边单元之间的通信提供高效的认证和隐私保护,使聚合签名的验证过程不因个别无效签名的存在而导致所聚合的所有签名验证失败,提高聚合签名的验证效率。方法将无证书密码体制和聚合签名算法相结合设计应用在车联... 详细信息

目的为车联网中车辆与路边单元之间的通信提供高效的认证和隐私保护,使聚合签名的验证过程不因个别无效签名的存在而导致所聚合的所有签名验证失败,提高聚合签名的验证效率。方法将无证书密码体制和聚合签名算法相结合设计应用在车联网场景下的具有容错性质的无证书聚合签名方案。方案采用实时更新的伪身份为车辆提供隐私保护。结果在随机预言机模型下将方案的安全性规约到椭圆曲线离散对数问题上,证明了签名方案满足不可伪造性。结论与同类型方案对比分析表明,本文方案有较高的效率和良好的性能。

关键词：无证书密码体制容错聚合签名车联网隐私保护