检索结果-南通市图书馆

Towards fully automated GW band structure calculations:What we can learn from 60.000 self-energy evaluationsTowards fully automated GW band structure calculations:What we can learn from 60.000 self-energy evaluations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

npj Computational Materials 2021年第1期7卷 189-197页

作者： Asbjørn rasmussen Thorsten Deilmann Kristian SThygesen CAMD Department of PhysicsTechnical University of Denmark2800 Kongens LyngbyDenmark Center for Nanostructured Graphene(CNG) Technical University of Denmark2800 Kongens LyngbyDenmark Institut für Festkörpertheorie Westfälische Wilhelms-Universität Münster48149 MünsterGermany

We analyze a data set comprising 370 GW band structures of two-dimensional(2D)materials covering 14 different crystal structures and 52 chemical *** band structures contain a total of 61716 quasiparticle(QP)energies obtained from plane-wavebased one-shot G0W0@PBE calculations with full frequency *** investigate the distribution of key quantities,like the QP self-energy corrections and QP weights,and explore their dependence on chemical composition and magnetic *** linear QP approximation is identified as a significant error source and we propose schemes for controlling and drastically reducing this error at low computational *** analyze the reliability of the 1/N basis set extrapolation and find that is well-founded with a narrow distribution of coefficients of determination(r^(2))peaked very close to ***,we explore the accuracy of the scissors operator approximation and conclude that its validity is very *** work represents a step towards the development of automatized workflows for high-throughput G0W0 band structure calculations for solids.

关键词： structure approximation weights

Management of Gestational Trophoblast Disease: A Review Integrative National and International Guidelines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health 2022年第12期14卷 1321-1333页

作者： Marcela Curvêllo Beltrão Maira de lima Oliveira Mota Elizabeth Bacha Lusitania Maria de Barros Livia Helena Gomes de Barros Brandão Nelson Henriky Felix Mascarenhas Tallys leandro Barbosa da Silva Maria Fernanda Telles Pires de Souza Séfora Maria Fragoso Braga Victoria de Oliveira Carmo Borges Centro Universitário Tiradentes (UNIT) Maceió Brasil Instituto de Medicina Integral Professor Fernando Figueira (IMIP) Pernambuco Brasil Estácio de Juazeiro do Norte (FMJ) Ceará Brasil Universidade Federal de Alagoas (UFAL) Maceió Brasil Sã o Leopoldo Mandic Campinas Brasil Hospital Regional de Arapiraca Arapiraca Brasil

GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdeveloped countries, colliding with the economic barrier. The frequent absence of clear protocols and guidelines for the correct diagnosis and treatment of the aforementioned pathology results in inadequate risk classification, imprecise treatment and failed post-therapeutic observation, increasing the risk of relapses, morbidity and mortality. The present study aims to compare the different national and international guidelines in the management of GTD, through an integrative review. Nine articles were selected and it was observed that the main international reference centers are agreed with the management suggested by the IFGO (International Federation of Gynecology and Obstetrics), being the conduct in the Hydatidiform Mole (HM): evacuation by suction and curettage under ultrasound guidance, followed by hCG monitoring every 1 - 2 weeks until normalized;in low-risk GTN (Gestational Trophoblastic Neoplasm): chemotherapy with methotrexate or actinomycin D, in high-risk: EMA/CO protocol, in ultra-high-risk EMA/PE, methotrexate with radiotherapy for brain metastases. All medical societies recommend the registration of these patients in GTD screening centers, endorse the use of the IFGO scoring system (2000) and recommend the surgical management of placental site trophoblastic or epithelioid tumors, as chemotherapy is less effective in these cases. The controversies are in the proper follow-up after the treatment of HM, use of ultrasound to evacuate the uterus, administration of anti-D immunoglobulin, time of oxytocin infusion and rescue regimens that can be used in cases of resistant or recurrent GTN. Establishing and complying with consistent guidelines can improve patient care, with early diagnosis of the pathology and its complications, reducing the rate of

关键词： Guidelines Gestational Trophoblastic Disease Treatment

B-1 cells modulate the murine macrophage response to Leishmania major infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Biological Chemistry 2017年第2期8卷 151-162页

作者： Angelica F Arcanjo Marise P Nunes Elias B Silva-Junior Monique leandro Juliana Dutra Barbosa da Rocha Alexandre Morrot Debora Decote-Ricardo Celio Geraldo Freire-de-lima Instituto de Biofísica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Instituto Oswaldo Cruz FIOCRUZ Instituto de Microbiologia Paulo de Góes Universidade Federal do Rio de Janeiro Instituto de Veterinária Universidade Federal Rural do Rio de Janeiro

AIM To investigate the modulatory effect of B-1 cells on murine peritoneal macrophages infected with Leishmania major(L. major) in *** Peritoneal macrophages obtained from BALB/c andBALB/c XID mice were infected with L. major and cultured in the presence or absence of B-1 cells obtained from wild-type BALB/c mice. Intracellular amastigotes were counted, and interleukin-10(IL-10) production was quantified in the cellular supernatants using an enzymelinked immunosorbent assay. The levels of the lipid mediator prostaglandin E2(PGE2) were determined using a PGE2 enzyme immunoassay kit(Cayman Chemical, Ann Arbor, MI), and the number of lipid bodies was quantified in the cytoplasm of infected macrophages in the presence and absence of B-1 cells. Culturing the cells with selective PGE2-neutralizing drugs inhibited PGE2 production and confirmed the role of this lipid mediator in IL-10 production. In contrast, we demonstrated that B-1 cells derived from IL-10 KO mice did not favor the intracellular growth of L. *** We report that B-1 cells promote the growth of L. major amastigotes inside peritoneal murine macrophages. We demonstrated that the modulatory effect was independent of physical contact between the cells, suggesting that soluble factor(s) were released into the cultures. We demonstrated in our co-culture system that B-1 cells trigger IL-10 production by L. major-infected macrophages. Furthermore, the increased secretion of IL-10 was attributed to the presence of the lipid mediator PGE2 in supernatants of L. major-infected macrophages. The presence of B-1 cells also favors the production of lipid bodies by infected macrophages. In contrast, we failed to obtain the same effect on parasite replication inside L. major-infected macrophages when the B-1 cells were isolated from IL-10 knockout mice. CONCLUSION Our results show that elevated levels of PGE2 and IL-10 produced by B-1 cells increase L. major growth, as indicated by the number of parasites

关键词： Leishmania major Macrophages B-1 cells Interleukin-10 Prostaglandin E2 Infection

Medium carbon steel deep drawing:a study on the evolution of mechanical properties,texture and simulations,from cold rolling to the end product

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medium carbon steel deep drawing:a study on the evolution of...

Identification of New Genes Related to Virulence of Xanthomonas axonopodisPv. Citriduring Citrus Host Interactions

第五届国际材料与热加工物理模拟及数值模拟学术会议

作者： Ronald L. Plaut Angelo F. Padilha Nelson. B. lima Clara Herrera Antenor Ferreira Filho leandro H.Yoshimura University of So Paulo Brazil Professor IPEN-CNEN/SP So Paulo Brazil Professor Max-Planck-Institut für Eisenforschung Germany PhD Industrial Director Brasmetal Waelzholz S/A Diadema Brazil PhD Tech Manager CCS Consulting- So Paulo Brazil

Medium carbon steels are mostly used for simple applications;nevertheless new applications have been developed for which good sheet formability is required. This class of steels has an inherent low formability. A medium carbon hot rolled SAE 1050 steel has been selected for this study. It has been cold rolled with reductions in the 7 to 80% range. Samples have been used to assess the cold work hardening curve. For samples with a 50 and 80% thickness reduction, an annealing heat treatment has been performed to obtain recrystallization. The material has been characterized in the "as received", cold rolled and annealed conditions, using several methods: optical microscopy, X-ray diffraction (texture), Vickers hardness and tensile testing. The 50% cold rolled and recrystallized material has been further studied in terms of sheet metal formability and texture evolution during the actual stamping of a steel toe cap that has been used to validate the FEM simulations.

关键词： medium carbon steels texture mechanical properties deep drawing forming limit diagram FEM simulations.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Advances in Microbiology 2017年第1期7卷 22-46页

作者： Cristiano B. Ferreira leandro M. Moreira Joice B. Brigati Lonjoré L. lima Jesus A. Ferro Maria I. T. Ferro Julio C. F. de Oliveira Department of Technology Faculty of Agricultural Sciences and Veterinary S&atilde o Paulo State University (UNESP) Jaboticabal SP Brazil Citriculture Research Center Sylvio Moreira (IAC-Campinas) SP Brazil Department of Biological Sciences Institute of Exact and Biological Sciences Federal University of Ouro Preto Ouro Preto MG Brazil Research Center in Biological Sciences (NUPEB) Department of Biological Sciences Institute of Exact and Biological Sciences Federal University of Ouro Preto Ouro Preto MG Brazil Plant Healthy Department Faculty of Agricultural Sciences and Veterinary S&atilde o Paulo State University (UNESP) Jaboticabal SP Brazil Department of Biological Sciences Federal University of S&atilde o Paulo (UNIFESP) Diadema SP Brazil

A mutant library of the bacterium Xanthomonas citri subsp. citri strain 306 pathotype A (Xac), the causative agent of most aggressive Asiatic type A citrus canker, was screened regarding altered canker symptoms after inoculations into Citrus sinensis and Citrus limonia host leaves. Twenty-six mutants have shown phenotypic virulence changes and have respectively knocked out gene identified by sequencing. In vivo growth curves were obtained for nine mutants to quantify how the mutations could affect pathogen’s adaptability to growth inside and attack host plant infected tissue. Among identified genes in mutated strains, we could find those that until now had not been reported as being involved in Xac adaptation and/or virulence, such as predicted to encode for xylose repressor-like protein (XACΔxylR), Fe-S oxidoredutase (XACΔaslB), helicase IV (XACΔhelD), ubiquinol cytochrome c oxidoreductase iron-sulfur subunit (XACΔpetA), chromosome partitioning protein (XACΔparB) and cell division protein FtsB (XACΔftsB), in addition to genes predicted to encode for hypothetical proteins. The new genes found in this study as being relevant to adaptation and virulence, improve the understanding of Xac fitness during citrus plant attack and canker symptoms development.

关键词： Xanthomonas axonopodis Pv. Citri Mutants Impaired Virulence

Sward Structural Characteristics and Performance of Beef Heifers Reared under Rotational Grazing Management on Campos Grassland

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2014年第7期5卷 1020-1029页

作者： Cezar Wancura Barbieri Fernando Luiz F. de Quadros Felipe Jochims émerson Mendes Soares leandro Bittencourt de Oliveira Régis Maximiliano R. Carvalho Gabriela Machado Dutra Felipe Xavier de lima Franciele Gusatto Natural Grassland Ecology Research Group (LEPAN-UFSM) Universidade Federal de Santa Maria Animal Science Department Santa Maria Brazil

This study aimed to evaluate the effect of two rest intervals on structural sward characteristics and productive performance of beef heifers reared on Campos grassland managed on rotational grazing. The treatments were two intervals between grazing of 375 and 750 DD (degree days), based on thermal cumulative sum for leaf expansion of native grasses belonging to two functional groups. The experimental design was a randomized complete block design with two treatments and three replications. The tested animals were beef heifers with initial age of 12 months and average weight of 185.2 ± 17.4 kg. Measures in the pasture were: herbage mass, mass of green leaf blades, stem mass, dead material mass and green leaf allowance. The 750 DD rest interval presented higher herbage mass (24%), higher green herbage mass and 19% more leaves in the canopy. This rest interval also presents a high proportion of dead material and stems in the sward structure. In the other way, the 375 DD rest interval presents better chemical characteristics, with 20% more crude protein in the hand plucking samples. Heifers’ dry matter intake was similar between the rest intervals (2.04% of live weight) and the bite mass was also similar (0.22 g DM per bite) but the animal performance was higher in the 375 DD rest interval. The stocking density showed similarity between treatments with an average of 875 kg/LW/ha. The live weight gain per area was higher in 40 kg/LW/ha (P = 0.117) for 375 DD rest interval, reaching 251 kg/LW/ha produced over the 149 experimental days. Based on these results, we can conclude that the treatment of shortest interval between defoliation gave the highest gain individual animals in warm seasons.

关键词： Average Daily Gain Duration of Leaf Expansion Herbage Mass Rotational Grazing Stocking Rate

Prevalence of Helicobacter pylori vacA,cagA,dupA and oipA Genotypes in Patients with Gastric Disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Microbiology 2017年第1期7卷 1-9页

作者： Mayara Luciana Sallas Jessica lima Melchiades Luanna Munhoz Zabaglia Juliana Ribeiro do Prado Moreno Wilson Aparecido Orcini Elizabeth Suchi Chen Marilia de Arruda Cardoso Smith Spencer Luiz Marques Payao Lucas Trevizani rasmussen Sagrado Coracao University(USC) BauruBrazil Federal University of Sao Paulo(UNIFESP) Sao PauloBrazil

Gastric diseases such as chronic gastritis and gastric cancer are most commonly caused by virulence factors of Helicobacter pylori (H. pylori), such as the vacA, cagA, dupA and oipA genes. Therefore, this study investigated the prevalence and the combination of these virulence factors from patients with gastric diseases. The endoscopic biopsies were obtained from 516 patients with gastric symptoms, 101 of which were from patients with normal gastric tissue, 365 of which were from patients with chronic gastritis, and 50 of which were from patients with gastric cancer. H. pylori and the virulence factors were detected by PCR. The oipA gene exhibited an increased risk for chronic gastritis (p = 0.0296), and the vacA gene demonstrated a risk for gastric cancer from chronic gastritis (p = 0.0002). Based on the combination of the virulence factors, cagA, vacA, dupA and oipA genes exhibited a high prevalence in patients with chronic gastritis and gastric cancer. The cagA+/dupA+ genotype demonstrated a significant correlation in patients with normal gastric mucosa (p = 0.0278). In the chronic gastritis group, a significant association was observed between the cagA+ and the vacA s1m1 genotypes (p cagA+/dupA+ genotypes (p = 0.0183), the dupA+/oipA+ genotypes (p cagA, vacA, dupA, and oipA genes, which contributed to the risk of developing gastroduodenal diseases. Furthermore, this is the first study to reveal a high prevalence of the oipA gene in H. pylori isolates in Brazil.

关键词： Helicobacter pylori Virulence Factors cagA dupA oipA vacA

Major Approaches on the Piezoelectric Device, Drills and Saws to Orthognathic Surgery: A Systematic Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health 2019年第6期11卷 783-791页

作者： Diego César Marques Vanessa Gabriela Gonzáles Pinto Rogério Luiz de Araújo Vian Regis Manzini leandro Aparecido Irrazabal Priscilla Janaína de lima Borelli Bovo Idiberto José Zotarelli Filho Elias Naim Kassis University Center North Paulista (Unorp) S&#227 o José do Rio Preto (SP) Brazil Post Graduate and Continuing Education (Unipos) S&#227 o José do Rio Preto (SP) Brazil Cristo Redentor Hospital Iporá Goáis Brazil Santa Casa de Misericórdia Hospital Servi&#231 o de Cirurgia e Traumatologia Bucomaxilofacial Ribeir&#227 o Preto (SP) Brazil Universida de Federal do Pampa (Unipampa) Campus Uruguaiana (RS) Brazil

Introduction: The incidence of lesions of sensory and motor nerves associated with oral and maxillofacial surgery is often underestimated, representing around 32.0% of all lesions, and orthognathic surgery contributes 12.3% to these lesions. Thus, the use of piezosurgery (PiZCi) has been indicated in several procedures within oral and maxillofacial surgery due to a number of advantages over conventional drill and saw techniques. Objective: to analyze the main literature on the use of the piezoelectric device in relation to the use of drills and to orthognathic surgery in dentistry. Methods: A total of 41 articles were found involving Orthognathic Surgery, Piezoelectric Device, Drills Device, Saws Device, and Efficiency. Initially, it was held the exclusion existing title and duplications following the interest described this work. After this process, the summaries were evaluated, and a new exclusion was held. 29 articles were included and discussed in this study. Initially, the keywords were determined by searching the DeCS tool (Descriptors in Health Sciences, BIREME base) and later verified and validated by MeSh system (Medical Subject Headings, the US National Library of Medicine). Results and conclusion: It was concluded that the piezoelectric device has excelled with an effective surgical technique, being able to be indicated in the most diverse areas of the oral surgery, providing accurate, clean and minimally traumatic osteotomies for the soft tissues, intraoperative bleeding, when compared to conventional surgery using drills and/or saws.

关键词： Orthognathic Surgery Piezoelectric Device Drills Device Saws Device Efficiency

Bacterial Fecal Microbiota in Healthy Subjects and Inpatients with Clostridium difficileInfection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Microbiology 2017年第1期7卷 10-21页

作者： Thaís Flecher Barbosa Danielle Angst Secco Raquel Silva Peixoto Alexandre Soares Rosado Flavia lima do Carmo Hugo Emiliano de Jesus leandro Araujo Lobo Luis Caetano Martha Antunes Karla Rodrigues Miranda Geraldo Renato de Paula Regina Maria Cavalcanti Pilotto Domingues Instituto de Microbiologia Paulo de Goes Universidade Federal do Rio de Janeiro Rio de Janeiro RJ Brazil Escola Nacional de Saúde Pública Sergio Arouca Fundacao Oswaldo Cruz Rio de Janeiro RJ Brazil Faculdade de Farmácia Universidade Federal do Rio de Janeiro—Campus Macaé Macaé RJ Brazil Departamento de Tecnologia Farmacêutica Universidade Federal Fluminense Niterói RJ Brazil

Clostridium difficile is a nosocomial enteric pathogen, considered the main etiological agent of antibiotic-associated diarrhea in hospitals. C. difficile is resistant to several antimicrobial agents used in empiric treatment protocols, which confers selective advantages to this species as compared with other members of the intestinal microbiota. The aim of this study was to evaluate and identify possible alterations of the intestinal microbiota population resulting from the use of antimicrobials associated with infections by C. difficile (CDI). Denaturing Gradient Gel Electrophoresis (DGGE) was used to evaluate fecal samples from two groups: healthy subjects and patients with C. difficile-associated diarrhea (CDAD). A decrease in bacterial diversity was highlighted by the low number of bands in samples from CDAD patients, compared with healthy subjects. This may indicate that antibiotic treatment would affect bacterial diversity, leading to a significant difference between the intestinal microbiota of these two groups, but further studies are still needed. Firmicutes and Verrucomicrobia phyla were detected mainly in healthy individuals, and these could be related to protection factors against the CDI. Klebsiella variicola/K. pneumoniae were found mostly in samples from CDI patients. This study shows the effects of antimicrobials and the CDI itself on human intestinal microbiota.

关键词： Clostridium difficile DGGE Microbiota CDAD Antimicrobials