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Risk factors of infected pancreatic necrosis secondary to severe acute pancreatitis

Hepatobiliary & Pancreatic Diseases International 2016年第4期15卷 428-433页

作者： Liang Ji Jia-Chen Lv Zeng-Fu Song mai-Tao Jiang le Li Bei Sun Department of Pancreatic and Biliary Surgery First Affiliated Hospital of Harbin Medical University

BACKGROUND： Severe acute pancreatitis（SAP） remains a clinical challenge with considerable morbidity and *** early identification of infected pancreatic necrosis（IPN）, a life-threatening evolution secondary to SAP, is obliged for a more preferable prognosis. Thus, the present study was conducted to identify the risk factors of IPN secondary to SAP. METHODS： The clinical data of patients with SAP were retrospectively analyzed. Univariate and multivariate logistic regression analyses were sequentially performed to assess the associations between the variables and the development of IPN secondary to SAP. A receiver operating characteristic（ROC） curve was created for each of the qualified independent risk factors. RESULTS： Of the 115 eligible patients, 39（33.9%） progressed to IPN, and the overall in-hospital mortality was 11.3%（13/115）.The early enteral nutrition（EEN）（P=0.0092, OR=0.264）, maximum intra-abdominal pressure（IAP）（P=0.0398, OR=1.131）and maximum D-dimer level（P=0.0001, OR=1.006） in the first three consecutive days were independent risk factors associated with IPN secondary to SAP. The area under ROC curve（AUC） was 0.774 for the maximum D-dimer level in the first three consecutive days and the sensitivity was 90% and the specificity was 58% at a cut-off value of 933.5 μg/L; the AUC was 0.831 for the maximum IAP in the first three consecutive days and the sensitivity was 95% and specificity was 58%at a cut-off value of 13.5 mm Hg. CONCLUSIONS： The present study suggested that the maximum D-dimer level and/or maximum IAP in the first three consecutive days after admission were risk factors of IPN secondary to SAP; an EEN might be helpful to prevent the progression of IPN secondary to SAP.

关键词： D-dimer enteral nutrition infected pancreatic necrosis intra-abdominal pressure risk factor severe acute pancreatitis

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圆叶青藤内生真菌Phlebiopsis crassa次生代谢产物研究

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化学研究与应用 2024年第8期36卷 1915-1921页

作者：赵冕唐蓉蓉冯子迈刘玉衡王意浓蔡乐贾庆忠河北医科大学教学实验中心河北石家庄050017 云南大学化学科学与工程学院云南昆明650091 河北医科大学药学院河北石家庄050017

本文对分离自圆叶青藤(Illigera orbiculata ***)的一株内生真菌Phlebiopsis crassa MYYJ-5-1的次生代谢产物进行了研究,从其土豆固体发酵物中分离得到9个化合物,分别鉴定为:benzophenone(1)、p-hydroxybenzoic acid(2)、p-hydroxybenzaldehyde(3)、indole-3-carboxaldehyde(4)、indole-3-carboxylic acid(5)、thymidine(6)、uracil(7)、thymine(8)、mono-methyl succinate(9)。同时采用二倍稀释法对化合物进行体外抗植物病原菌活性测定,结果显示:化合物1和3对黄瓜萎蔫球菌具有中等抑制活性,MIC值均为32μg·mL^(-1);化合物5对人参链格孢菌具有中等抑制活性,MIC值为32μg·mL^(-1);化合物6对黑曲霉菌具有显著抑制活性,活性等同于阳性对照制霉素,MIC值均为16μg·mL^(-1)。

关键词：圆叶青藤 Phlebiopsis crassa 次生代谢产物抗植物病原菌活性

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Anti-inflammatory effects of Solanum procumbens on a low dose complete Freund's adjuvant-induced arthritis rat model

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Asian Pacific Journal of Tropical Biomedicine 2023年第5期13卷 214-221页

作者： Xuan-Hai Do Trong Nghia Nguyen Thanh Chung Dang thi Thanh mai Nguyen Trung Nhan Nguyen Van Nhat Truong Do Huu Tho le Xuan Hai Nguyen Hoan. Phu Dang Giang-Linh Nguyen Dinh-Khanh Hoan. Van-Quan le Van-Mao Can Department of Practical and Experimental Surgery Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Reconstructive and Microsurgery Craniofacial and Reconstructive Surgery CentreMilitary Central Hospital 108Hanoi 10000Vietnam Department of Anatomic Pathology Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Faculty of Chemistry University of ScienceVietnam National University Ho Chi Minh CityHo Chi Minh City 70000Vietnam Faculty of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi 10000Vietnam Department of Ultrasound Imaging Diagnostics CentreMilitary Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Functional Diagnostics Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Pathophysiology Vietnam Military Medical UniversityHanoi 10000Vietnam

Objective:To investigate the anti-inflammatory and analgesic effects of Solanum procumbens on complete Freund’s adjuvantinduced arthritis rat ***:We isolated and identified five compounds in the ethanolsoluble Solanum procumbens extract(SP)with anti-inflammatory effects,including ursolic acid,β-sitosterol,hexadecanoic acid,cisvaccenic acid,and vanillic ***,we investigated the anti-inflammatory effects of SP on rheumatoid arthritis symptoms,including paw volumes,local temperatures,withdrawal latency,and mechanical withdrawal threshold at the hind paw and white blood cell(WBC)number from complete Freund’s adjuvant-induced arthritis rat ***:We have successfully established a complete Freund’s adjuvant-induced arthritis rat model at a low dose(1 mg/mL).SP extract significantly reduced paw volumes(P<0.05),prolonged withdrawal latencies(P<0.05),decreased local temperature,and increased the mechanical withdrawal threshold(P<0.05),but only SP extract at the dose of 300 mg/kg significantly decreased WBC ***:SP extract could be a potential medication candidate with anti-inflammatory effects for arthritis,but it requires further investigation into the mechanism of the SP and its effectiveness on other models as well as clinical trials.

关键词： Solanum procumbens Arthritis Anti-inflammation Complete Freund's adjuvant Rats

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Effect of Fabrication Process on the Hydrophilic Properties of Porous TiO2 thin Films for Self-Cleaning Application

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材料科学与工程（中英文B版） 2016年第3期6卷 126-130页

作者： Nguyen thi mai Huong Nguyen Thanh Binh le thi Thu Huong Nguyen Dinh Dung Nguyen Trong Tinh Institute of Applied Physics and Scientific Instruments Vietnam Academy of Science and Technology Cau Giay Dist Hanoi Vietnam

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New Information and Communication Technologies and University Education Renovation in Vietnam

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Journalism and Mass Communication 2012年第9期2卷 917-924页

作者： le mai Huong Vietnam National University Hanoi Vietnam

The introduction of new information and communication technologies in Vietnam has had significant impacts on every sector, and changed the face of the whole Vietnamese society. New cultures, customs, and norms have been introduced to compete with the country＇s traditional values. In the context of Vietnamese sustained economic growth and social development, university education in Vietnam falls behind those from regional countries, partly because the influences of＇ information and communication technologies to the society as well as the education system at the paradigm levels have not been properly understood. In order to reverse this trend, a comprehensive renovation in university education must be carried out, and one of the first issues to be addressed is to reach a national consensus on the traditional and emerging social and educational values in Vietnam.

关键词： university education information and communication intemet impacts Vietnam

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Integrated Coastal Flood Risk Management as a Means to Build Resilient Communities

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Journal of Hydraulic Engineering 2016年第1期2卷 52-59页

作者： Huynh thi Lan Huong Nguyen mai Dang W. Grabs le Huu Ti M. Marchand Institute of Meteorology Hydrology and Climate Change (IMHEN) Viet Nam Water Resources University Viet Nam Associated Programme on Flood Management World Meteorological Organization Federal Institute of Hydrology Germany Deltares the Netherlands

There is a clear trend in the increase of damages and loss of lives and livelihoods in coastal areas as a result of rapid increase in coastal populations, and overall socio-economic development in coastal regions resulting in an increase in vulnerability of populations exposed to coastal floods and exposed infrastructure. Coastal flooding as a result of i.e. storm surges are difficult to predict and cannot be prevented, however there are means to apply integrated flood risk management approaches aiming to reduce the impact of coastal floods. A measure of the effectiveness of such approaches is the awareness and response of coastal communities to coastal flood risks. The paper introduces best practices and methods to lower coastal flood risk at the level of provinces, districts and the community level. this includes advances in coastal flood forecasting and early warning practices, improvement of institutional preparedness and integrated flood management practices as well as measures at the community level aiming to strengthen their resilience to coastal floods. The paper provides a showcase for the historical development and achievements to pave ways for the eventual implementation of a pilot project on integrated flood risk management in coastal areas in central Viet Nam.

关键词： Coastal flood management communities integrated flood management resilience Viet Nam.

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The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis

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Journal of Integrative Plant Biology 2022年第10期64卷 1916-1934页

作者： Yi Yang Fang Liu le Liu Mingyue Zhu Jinfeng Yuan Yan‐Xia mai Jun‐Jie Zou Jie le Yonghong Wang Klaus Palme Xugang Li Yong Wang Long Wang State Key Laboratory of Crop Biology College of Life SciencesShandong Agricultural UniversityDaizong Street 61Tai'an 271018China Shandong Provincial Key Laboratory of Biophysics Institute of BiophysicsDezhou UniversityDezhou 253023China Sino‐German Joint Research Center on Agricultural Biology College of Life SciencesShandong Agricultural UniversityDaizong Street 61Tai'an 271018China Faculty of Biology Institute of Biology II/Molecular Plant PhysiologyAlbert‐Ludwigs‐University of FreiburgSchänzlestrasse 1Freiburg D‐79104Germany National Key Laboratory of Plant Molecular Genetics(NKLPMG) CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and Ecology(SIPPE)Chinese Academy of Sciences(CAS)Shanghai 200032China Biotechnology Research Institute Chinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory of Plant Molecular Physiology CAS Center for Excellence in Molecular Plant SciencesInstitute of BotanyChinese Academy of SciencesBeijing 100093China University of Chinese Academy of Sciences Beijing 100049China

Gravity-induced root curvature involves the asymmetric distribution of the phytohormone *** response depends on the concerted activities of the auxin transporters such as PIN-FORMED(PIN)proteins for auxin efflux and AUXIN RESISTANT 1(AUX1)for auxin ***,how the auxin gradient is established remains *** we identified a new mutant with a short root,strong auxin distribution in the lateral root cap and an impaired gravitropic *** causal gene encoded an Arabidopsis homolog of the human unconventional prefoldin RPB5 interactor(URI).At URI interacted with prefoldin 2(PFD2)and PFD6,twoβ-type PFD members that modulate actin and tubulin patterning in *** auxin reporter DR5_(rev):GFP showed that asymmetric auxin redistribution after gravistimulation is disordered in aturi-1 root *** with the endomembrane protein trafficking inhibitor brefeldin A indicated that recycling of the auxin transporter PIN2 is disrupted in aturi-1 roots as well as in pfd *** propose that At URI cooperates with PFDs to recycle PIN2and modulate auxin distribution.

关键词： Arabidopsis auxin cytoskeleton PIN2 prefoldin(PFD) unconventional prefoldin RPB5 interactor(URI)

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Organic photovoltaic devices with high open-circuit voltage based on oligothiophene derivatives

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Chinese Chemical letters 2007年第4期18卷 437-440页

作者： Ping Liu Jia le Huang Wan Zhang Pan Ming Sheng Huang Wen Ji Deng Yu Liang mai An Bo Luan Research Institute of Materials Science South China University of Technology Guangzhou 510640 China Department of Applied Physics South China University of Technology Guangzhou 510640 China Gungdong Province Petroleum Chemicals Institute Guangzhou 510665 China

For the purpose of developing organic photovoltaic devices with good performance characteristics, we have fabricated two devices using 4T-CHO, 5T-CHO and PTCDA. The ITO/4T-CHO/PTCDA/Al device has a Voc of 2.45 V and photoelectric conversion efficiency of 2.76%. The ITO/ST-CHO/PTCDA/Al device has a Voc of 2.1 3V and photoelectric conversion efficiency of 2.90%. The two devices have higher Voc （2.45 and 2.13 V）. It is possible that intennolecular hydrogen bonding between -CHO group of nT-CHO and carboxylic dianhydride of PTCDA contribute to enhance the efficiency by promoting interracial electron transfer and eliminating the subconducting band trap sites.

关键词： Oligothiophene Organic photovoltaic property Device

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Antineoplastic Drug Handling:Higher Risk for Healthcare Workers in Tunisia than in France?

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Biomedical and Environmental Sciences 2020年第10期33卷 803-806页

作者： Kaouther Zribi Laetitia Minh mai le Asok Rajkumar Hail Aboudagga Mounir Frikha Amandine Dietrich Emna Zribi Fathi Safta Eric Caudron Faculty of Pharmacy of Monastir-University of Monastir Rue Avicenne Monastic Tunisie Service de Pharmacie Hopital europeen Georges PompidouAssistance Publique-Hopitaux de Paris Centre Universite-Paris20 rue LeblancParis 75015France Universite Paris-Saclay LipidesSystemes Analytiques et BiologiquesChatenay-Malabry 92296France Oncolgy department Centre hospitalo-universitaire Habib BourguibaRue Ferdaous SfaxTunisie Oncology Department Hopital europeen Georges PompidouAssistance Publique-Hopitaux

In 2018,the World Health Organization(WHO)reported 9.6 million cancer deaths worldwide,in accordance with the data collected by the International Agency for Research on Cancer(IARC).The fight against cancer and other ... 详细信息

关键词： cancer Cancer diseases

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Isolation and Identification of Arbuscular Mycorrhizal Fungi from Agricultural Fields of Vietnam

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American Journal of Plant Sciences 2012年第12期3卷 1796-1801页

作者： Zita Sasvári Franco Magurno Dóra Galanics Tran thi Nhu Hang Tran thi Hong Ha Nguyen Dinh Luyen le mai Huong Katalin Posta Microbiology and Environmental Toxicology Group Institute of Plant ProtectionSzent István UniversityGodolloHungary Experimental Biology Laboratory Institute of Natural Products Chemistry(INPC)Vietnam Academy of Science and Technology(VAST)HanoiVietnam

The rising claim for more environmental friendly and healthy agriculture is a strong incentive to find alternative strategies to replace the use of mineral fertilizer and pesticide. Arbuscular mycorrhizal fungi (AMF), a main component of soil microbiota, represent a promising tool as providers of key ecological services. The present work represented one of the first attempts to study, under a morphological and molecular point of view, the AMF communities associated to some strategic crops in Vietnam. The findings about the AMF morphotypes dominant in different crop systems could be a starting point for the development of well performing and adapted inocula suitable for the application in field.

关键词： Arbuscular mycorrhizal Fungi Spore Density Vietnam Crops

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